Objective:CRRT in treatment of severe renal failure. Methods:A high flux dialyzer with a single pump was used to make an 100～200 ml/min flux and 10～20 ml/min ultrafiltration.The average treatment period was 8.4 hour...Objective:CRRT in treatment of severe renal failure. Methods:A high flux dialyzer with a single pump was used to make an 100～200 ml/min flux and 10～20 ml/min ultrafiltration.The average treatment period was 8.4 hours, while the longest treatment lasted 72 hours with 12～16 L/d of replacement-solution and 0.2～4.3 L/d of net ultrafiltration. CVVHD was applied to some patients with high level of toxin, with blood flow at 50~100 ml/min and ultrafiltration rate at 8～12 ml/min and hemodialysis flux at 10～20 ml/min; 1.5% glucose dialysis solution was used as the replacement-solution and the delivering rate was controlled at 20～30 ml/min. Most treatments continued for 9 hours. Results: 5 patients with severe hypotension cant tolerate the treatment, 13 traumas complicated with renal failure died, 4 septic shock patients with MODS died,16 patients recovered or shifted to regular dialysis. Conclusions: CRRT can pull the water from intracellular into the blood continuously, So it can reduce the interference on the stability of cardiovascular system. and it works effectively on correcting the pathogenic distribution of body fluid quickly and ameliorating tissue edema of lung and brain.展开更多
文摘Objective:CRRT in treatment of severe renal failure. Methods:A high flux dialyzer with a single pump was used to make an 100～200 ml/min flux and 10～20 ml/min ultrafiltration.The average treatment period was 8.4 hours, while the longest treatment lasted 72 hours with 12～16 L/d of replacement-solution and 0.2～4.3 L/d of net ultrafiltration. CVVHD was applied to some patients with high level of toxin, with blood flow at 50~100 ml/min and ultrafiltration rate at 8～12 ml/min and hemodialysis flux at 10～20 ml/min; 1.5% glucose dialysis solution was used as the replacement-solution and the delivering rate was controlled at 20～30 ml/min. Most treatments continued for 9 hours. Results: 5 patients with severe hypotension cant tolerate the treatment, 13 traumas complicated with renal failure died, 4 septic shock patients with MODS died,16 patients recovered or shifted to regular dialysis. Conclusions: CRRT can pull the water from intracellular into the blood continuously, So it can reduce the interference on the stability of cardiovascular system. and it works effectively on correcting the pathogenic distribution of body fluid quickly and ameliorating tissue edema of lung and brain.
