In view of the characteristics of physiology,anatomyand absorbability of the rectum,rectal administration seems tobe a new approach and an effective method for application ofChinese herbal medicine.Based on the experi...In view of the characteristics of physiology,anatomyand absorbability of the rectum,rectal administration seems tobe a new approach and an effective method for application ofChinese herbal medicine.Based on the experiential formula ofDr.He Shaoshan(a famous and veteran TCM doctor),thepharmaceutical department of our hospital has developed aseries of medicinal herbal products for gynecological use,yielding satisfactory therapeutic results.The No.4Gynecological Herbal Enema is one of the series,and it isbriefly introduced as follows.展开更多
Objective: Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder, and a symptom-based diagnosis. Because of the unclear mechanisms, the treatment available have not acquired the satisfied effe...Objective: Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder, and a symptom-based diagnosis. Because of the unclear mechanisms, the treatment available have not acquired the satisfied effect. We performed a meta-analysis to assess the effectiveness and safety of herbal enema in treating IBS compared to the calcium channel blocker administration. Methods: We searched for randomized controlled trials(RCTs) testing herbal enema in patients with IBS which compared to the calcium channel blocker administration in Pub Med, EMMBASE, the Chinese National Knowledge Infrastructure(CNKI), the Wan-fang Database and the VIP Database up to May 2016 with no language restrictions. Primary outcome was the global symptom improvement and secondary outcome was the symptom severity scale score. Safety was also assessed. We used Revman 5.3 to estimate the pooled mean difference(MD) for continuous outcomes and relative risk(RR) for binary outcome measures, with a 95% confidence interval(CI).Results: Five studies(230 patients in experimental group and 209 patients in control group) were included in the meta-analysis. The results showed that herbal enema as the sole intervention or combined with other treating methods could significantly promote the global symptom improvement and mucous stool scale and has potential to improve abdominal distention compared to the calcium channel blocker administration. But there was no difference between the two groups in abdominal pain. The recurrence rate was lower than the control group. Conclusions: The study indicated that herbal enema may be an effective assistant means for IBS.展开更多
文摘In view of the characteristics of physiology,anatomyand absorbability of the rectum,rectal administration seems tobe a new approach and an effective method for application ofChinese herbal medicine.Based on the experiential formula ofDr.He Shaoshan(a famous and veteran TCM doctor),thepharmaceutical department of our hospital has developed aseries of medicinal herbal products for gynecological use,yielding satisfactory therapeutic results.The No.4Gynecological Herbal Enema is one of the series,and it isbriefly introduced as follows.
基金supported by the Key Project of Shanghai 3-year plan (ZY3-CCCX-2-1002)
文摘Objective: Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder, and a symptom-based diagnosis. Because of the unclear mechanisms, the treatment available have not acquired the satisfied effect. We performed a meta-analysis to assess the effectiveness and safety of herbal enema in treating IBS compared to the calcium channel blocker administration. Methods: We searched for randomized controlled trials(RCTs) testing herbal enema in patients with IBS which compared to the calcium channel blocker administration in Pub Med, EMMBASE, the Chinese National Knowledge Infrastructure(CNKI), the Wan-fang Database and the VIP Database up to May 2016 with no language restrictions. Primary outcome was the global symptom improvement and secondary outcome was the symptom severity scale score. Safety was also assessed. We used Revman 5.3 to estimate the pooled mean difference(MD) for continuous outcomes and relative risk(RR) for binary outcome measures, with a 95% confidence interval(CI).Results: Five studies(230 patients in experimental group and 209 patients in control group) were included in the meta-analysis. The results showed that herbal enema as the sole intervention or combined with other treating methods could significantly promote the global symptom improvement and mucous stool scale and has potential to improve abdominal distention compared to the calcium channel blocker administration. But there was no difference between the two groups in abdominal pain. The recurrence rate was lower than the control group. Conclusions: The study indicated that herbal enema may be an effective assistant means for IBS.
