Owing to its heterogeneous and highly aggressive nature,hepatocellular carcinoma(HCC)has a high recurrence rate,which is a non-negligible problem despite the increasing number of available treatment options.Recent cli...Owing to its heterogeneous and highly aggressive nature,hepatocellular carcinoma(HCC)has a high recurrence rate,which is a non-negligible problem despite the increasing number of available treatment options.Recent clinical trials have attempted to reduce the recurrence and develop innovative treatment options for patients with recurrent HCC.In the event of liver remnant recurrence,the currently available treatment options include repeat hepatectomy,salvage liver transplantation,tumor ablation,transcatheter arterial chemoembolization,stereotactic body radiotherapy,systemic therapies,and combination therapy.In this review,we summarize the strategies to reduce the recurrence of high-risk tumors and aggressive therapies for recurrent HCC.Additionally,we discuss methods to prevent HCC recurrence and prognostic models constructed based on predictors of recurrence to develop an appropriate surveillance program.展开更多
目的探讨复发性鼻咽癌手术治疗前行改良颈内动脉栓塞术的有效性和安全性。方法本研究为回顾性研究。搜集2022年6月—2023年8月于福建中医药大学附属第二人民医院接受改良颈内动脉栓塞术治疗的13例复发性鼻咽癌患者的病例资料。记录围手...目的探讨复发性鼻咽癌手术治疗前行改良颈内动脉栓塞术的有效性和安全性。方法本研究为回顾性研究。搜集2022年6月—2023年8月于福建中医药大学附属第二人民医院接受改良颈内动脉栓塞术治疗的13例复发性鼻咽癌患者的病例资料。记录围手术期并发症,对比患者术前和术后30 d MRS评分,评估改良颈内动脉栓塞术的有效性和安全性。结果13例患者球囊封堵试验均为阴性,且都顺利完成改良颈内动脉栓塞术,完全闭塞颈内动脉。手术时长50.0~110.0 min,平均(63.7±15.3)min;均未出现弹簧圈逃逸。1例术后发生语言不清、肢体无力,给予升压等对症治疗症状消失;1例术后发生头痛、复视,出院前已恢复;1例由于对侧颈内动脉狭窄同期支架植入,术后植入支架侧出现高灌注脑出血表现,术后30 d MRS评分4分。其余患者均未发生围术期并发症,术后30 d MRS评分均为0分。结论针对复发性鼻咽癌侵犯颈内动脉的患者行改良颈内动脉栓塞术,可安全有效闭塞颈内动脉,降低后续鼻咽癌内镜手术中颈动脉出血发生率,提高患者生存预后。展开更多
文摘Owing to its heterogeneous and highly aggressive nature,hepatocellular carcinoma(HCC)has a high recurrence rate,which is a non-negligible problem despite the increasing number of available treatment options.Recent clinical trials have attempted to reduce the recurrence and develop innovative treatment options for patients with recurrent HCC.In the event of liver remnant recurrence,the currently available treatment options include repeat hepatectomy,salvage liver transplantation,tumor ablation,transcatheter arterial chemoembolization,stereotactic body radiotherapy,systemic therapies,and combination therapy.In this review,we summarize the strategies to reduce the recurrence of high-risk tumors and aggressive therapies for recurrent HCC.Additionally,we discuss methods to prevent HCC recurrence and prognostic models constructed based on predictors of recurrence to develop an appropriate surveillance program.
文摘目的探讨复发性鼻咽癌手术治疗前行改良颈内动脉栓塞术的有效性和安全性。方法本研究为回顾性研究。搜集2022年6月—2023年8月于福建中医药大学附属第二人民医院接受改良颈内动脉栓塞术治疗的13例复发性鼻咽癌患者的病例资料。记录围手术期并发症,对比患者术前和术后30 d MRS评分,评估改良颈内动脉栓塞术的有效性和安全性。结果13例患者球囊封堵试验均为阴性,且都顺利完成改良颈内动脉栓塞术,完全闭塞颈内动脉。手术时长50.0~110.0 min,平均(63.7±15.3)min;均未出现弹簧圈逃逸。1例术后发生语言不清、肢体无力,给予升压等对症治疗症状消失;1例术后发生头痛、复视,出院前已恢复;1例由于对侧颈内动脉狭窄同期支架植入,术后植入支架侧出现高灌注脑出血表现,术后30 d MRS评分4分。其余患者均未发生围术期并发症,术后30 d MRS评分均为0分。结论针对复发性鼻咽癌侵犯颈内动脉的患者行改良颈内动脉栓塞术,可安全有效闭塞颈内动脉,降低后续鼻咽癌内镜手术中颈动脉出血发生率,提高患者生存预后。
