Dyslipidemia is a risk factor for cardiovascular diseases（CVDs）in patients with diabetes,and non-high-density lipoprotein cholesterol（non-HDL-C）is a better predictor of CVDs than low-density lipoprotein cholestero...Dyslipidemia is a risk factor for cardiovascular diseases（CVDs）in patients with diabetes,and non-high-density lipoprotein cholesterol（non-HDL-C）is a better predictor of CVDs than low-density lipoprotein cholesterol（LDL-C）in patients with diabetes.Therefore,we aimed to investigate the distribution of non-HDL-C and the prevalence of high non-HDL-C level in Chinese patients with diabetes mellitus and identify the展开更多
Background:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis,especially in younger age groups,we undertook a series of active surveys among Qi...Background:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis,especially in younger age groups,we undertook a series of active surveys among Qinghai-Tibetan children in the Qinghai Province of Northwestern China in 2011 and 2012.The significant outcomes that resulted from this study emphasize the need to draw attention to echinococcosis,both alveolar echinococcosis(AE)and cystic echinococcosis(CE),so that policy development is promoted and suitable avenues for control are identified in the highly endemic areas on the Tibetan Plateau.Methods:A total of 19629 primary school students,aged 6-18 years,with a dominant Tibetan background underwent abdominal ultrasound examination,and 86.4%of the compliant students donated 2-5 ml of venous blood for serological tests.All the abnormal ultrasound results were recorded.If identified as echinococcosis,the disease lesion was assessed according to the WHO-Informal Working Group on Echinococcosis(WHO-IWGE)classification for AE and CE.Among the surveyed students,the prevalence by school was compared among geo-locations,sex and age groups.The clinical image presentations were analyzed according to lesion number,size,the location in the liver and the classification stage.Statistical significance was set at P-value<0.05 for comparisons among groups.Results:A total of 341 students(1.7%)were identified by ultrasound as having either CE(119,0.6%)or AE(222,1.1%).The highest prevalence rates of childhood AE cases occurred in the Tehetu(12.1%)and Moba(11.8%)townships in Dari County.There was a high seropositive rate(37.0%)and a heterogeneous distribution of cases,with a prevalence ranged from 0 to 12.1%for AE and 0-2.9%for CE.Moreover,the seropositive rate ranged from 0.7-45.1%across different schools.Conclusions:The high prevalence of echinococcosis in Qinghai-Tibetan primary school students reflects a lack of knowledge about Echinococcus spp.transmission.The combination of systematic education for children and regularly performed anthelmintic treatment for dogs could achieve the goal of sustainable hydatidosis control.展开更多
基金funded by the Scientific Research Foundation of the Health Bureau of Jilin Province,China(grant number:2011Z116)the National Natural Science Foundation of China with grant(grant number:81573230)
文摘Dyslipidemia is a risk factor for cardiovascular diseases（CVDs）in patients with diabetes,and non-high-density lipoprotein cholesterol（non-HDL-C）is a better predictor of CVDs than low-density lipoprotein cholesterol（LDL-C）in patients with diabetes.Therefore,we aimed to investigate the distribution of non-HDL-C and the prevalence of high non-HDL-C level in Chinese patients with diabetes mellitus and identify the
基金Our research was supported by the Natural Science Foundation of Qinghai,China for this project(No.2015-HZ-809).
文摘Background:As part of an ongoing program that aims to use early detection and timely treatment to improve the control of echinococcosis,especially in younger age groups,we undertook a series of active surveys among Qinghai-Tibetan children in the Qinghai Province of Northwestern China in 2011 and 2012.The significant outcomes that resulted from this study emphasize the need to draw attention to echinococcosis,both alveolar echinococcosis(AE)and cystic echinococcosis(CE),so that policy development is promoted and suitable avenues for control are identified in the highly endemic areas on the Tibetan Plateau.Methods:A total of 19629 primary school students,aged 6-18 years,with a dominant Tibetan background underwent abdominal ultrasound examination,and 86.4%of the compliant students donated 2-5 ml of venous blood for serological tests.All the abnormal ultrasound results were recorded.If identified as echinococcosis,the disease lesion was assessed according to the WHO-Informal Working Group on Echinococcosis(WHO-IWGE)classification for AE and CE.Among the surveyed students,the prevalence by school was compared among geo-locations,sex and age groups.The clinical image presentations were analyzed according to lesion number,size,the location in the liver and the classification stage.Statistical significance was set at P-value<0.05 for comparisons among groups.Results:A total of 341 students(1.7%)were identified by ultrasound as having either CE(119,0.6%)or AE(222,1.1%).The highest prevalence rates of childhood AE cases occurred in the Tehetu(12.1%)and Moba(11.8%)townships in Dari County.There was a high seropositive rate(37.0%)and a heterogeneous distribution of cases,with a prevalence ranged from 0 to 12.1%for AE and 0-2.9%for CE.Moreover,the seropositive rate ranged from 0.7-45.1%across different schools.Conclusions:The high prevalence of echinococcosis in Qinghai-Tibetan primary school students reflects a lack of knowledge about Echinococcus spp.transmission.The combination of systematic education for children and regularly performed anthelmintic treatment for dogs could achieve the goal of sustainable hydatidosis control.
