To better understand the heterogeneity of deep-crust and mantle interfaces in the region of the Three Gorges, China, we used the Parker-Oldenburg iterative inversion method to invert existing Bouguer gravity data from...To better understand the heterogeneity of deep-crust and mantle interfaces in the region of the Three Gorges, China, we used the Parker-Oldenburg iterative inversion method to invert existing Bouguer gravity data from the Three Gorges area （ 1 ： 500000） , a new gravity map of the Three Gorges Dam （ 1 ： 200000） , and the results of deep seismic soundings. The inversion results show a Moho depth of 42 km be- tween Badong and Zigui and the depth of the B2 lower-crustal interface beneath the Jianghan Plain and sur- rounding areas at 21 -25 km. The morphology of crustal interfaces and the surface geology present an over- pass structure. The mid-crust beneath the Three Gorges Dam is approximately 9 km thick, which is the thin- nest in the Three Gorges area and may be related to the shallow low-density body near the Huangling anti- cline. The upper crust is seismogenic, and there is a close relationship between seismicity and the deep- crust and mantle interfaces. For example, the MS. 1 Zigui earthquake occurred where the gradients of the Moho and the B2 interface are the steepest, showing that deep structure has a very important effect on re- gional seismicity.展开更多
BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patien...BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patient outcomes can be easily complicated by high-altitude polycythemia(HAPC),which increases the difficulty of treatment and the risk of recurrent thrombosis.To prevent reaching this point,effective screening and targeted interventions are crucial.Thus,this study analyzes and provides a reference for the clinical prediction of thrombosis recurrence in patients with lower-extremity DVT combined with HAPC.AIM To apply the nomogram model in the evaluation of complications in patients with HAPC and DVT who underwent anticoagulation therapy.METHODS A total of 123 patients with HAPC complicated by lower-extremity DVT were followed up for 6-12 months and divided into recurrence and non-recurrence groups according to whether they experienced recurrence of lower-extremity DVT.Clinical data and laboratory indices were compared between the groups to determine the influencing factors of thrombosis recurrence in patients with lowerextremity DVT and HAPC.This study aimed to establish and verify the value of a nomogram model for predicting the risk of thrombus recurrence.RESULTS Logistic regression analysis showed that age,immobilization during follow-up,medication compliance,compliance with wearing elastic stockings,and peripheral blood D-dimer and fibrin degradation product levels were indepen-dent risk factors for thrombosis recurrence in patients with HAPC complicated by DVT.A Hosmer-Lemeshow goodness-of-fit test demonstrated that the nomogram model established based on the results of multivariate logistic regression analysis was effective in predicting the risk of thrombosis recurrence in patients with lowerextremity DVT complicated by HAPC(χ^(2)=0.873;P>0.05).The consistency index of the model was 0.802(95%CI:0.799-0.997),indicating its good accuracy and discrimination.CONCLUSION The column chart model for the personalized prediction of thrombotic recurrence risk has good application value in predicting thrombotic recurrence in patients with lower-limb DVT combined with HAPC after discharge.展开更多
基金supported by grant 201008001 from China Earthquake Ad-ministration201156085 from Institute of Seismology,China Earthquake Administration
文摘To better understand the heterogeneity of deep-crust and mantle interfaces in the region of the Three Gorges, China, we used the Parker-Oldenburg iterative inversion method to invert existing Bouguer gravity data from the Three Gorges area （ 1 ： 500000） , a new gravity map of the Three Gorges Dam （ 1 ： 200000） , and the results of deep seismic soundings. The inversion results show a Moho depth of 42 km be- tween Badong and Zigui and the depth of the B2 lower-crustal interface beneath the Jianghan Plain and sur- rounding areas at 21 -25 km. The morphology of crustal interfaces and the surface geology present an over- pass structure. The mid-crust beneath the Three Gorges Dam is approximately 9 km thick, which is the thin- nest in the Three Gorges area and may be related to the shallow low-density body near the Huangling anti- cline. The upper crust is seismogenic, and there is a close relationship between seismicity and the deep- crust and mantle interfaces. For example, the MS. 1 Zigui earthquake occurred where the gradients of the Moho and the B2 interface are the steepest, showing that deep structure has a very important effect on re- gional seismicity.
基金Supported by Guiding Project of Qinghai Provincial Health Commission,No.2021-wjzdx-89.
文摘BACKGROUND Patients with deep venous thrombosis(DVT)residing at high altitudes can only rely on anticoagulation therapy,missing the optimal window for surgery or thrombolysis.Concurrently,under these conditions,patient outcomes can be easily complicated by high-altitude polycythemia(HAPC),which increases the difficulty of treatment and the risk of recurrent thrombosis.To prevent reaching this point,effective screening and targeted interventions are crucial.Thus,this study analyzes and provides a reference for the clinical prediction of thrombosis recurrence in patients with lower-extremity DVT combined with HAPC.AIM To apply the nomogram model in the evaluation of complications in patients with HAPC and DVT who underwent anticoagulation therapy.METHODS A total of 123 patients with HAPC complicated by lower-extremity DVT were followed up for 6-12 months and divided into recurrence and non-recurrence groups according to whether they experienced recurrence of lower-extremity DVT.Clinical data and laboratory indices were compared between the groups to determine the influencing factors of thrombosis recurrence in patients with lowerextremity DVT and HAPC.This study aimed to establish and verify the value of a nomogram model for predicting the risk of thrombus recurrence.RESULTS Logistic regression analysis showed that age,immobilization during follow-up,medication compliance,compliance with wearing elastic stockings,and peripheral blood D-dimer and fibrin degradation product levels were indepen-dent risk factors for thrombosis recurrence in patients with HAPC complicated by DVT.A Hosmer-Lemeshow goodness-of-fit test demonstrated that the nomogram model established based on the results of multivariate logistic regression analysis was effective in predicting the risk of thrombosis recurrence in patients with lowerextremity DVT complicated by HAPC(χ^(2)=0.873;P>0.05).The consistency index of the model was 0.802(95%CI:0.799-0.997),indicating its good accuracy and discrimination.CONCLUSION The column chart model for the personalized prediction of thrombotic recurrence risk has good application value in predicting thrombotic recurrence in patients with lower-limb DVT combined with HAPC after discharge.
