Clinical efficacy of intradermal type Ⅰ collagen injections in treating skin photoaging in patients from high-altitude areas

BACKGROUND Photoaging,a result of chronic sun exposure,leads to skin damage and pigmentation changes.Traditional treatments may have limitations in high-altitude areas like Yunnan Province.Intradermal Col Ⅰ injections stimulate collagen production,potentially improving skin quality.This study aims to assess the efficacy and safety of this treatment for photoaging.AIM To evaluate the efficacy and safety of intradermal typeΙcollagen(ColΙ)injection for treating photoaging.METHODS This prospective,self-controlled study investigated the impact of intradermal injections of ColΙon skin photodamage in 20 patients from the Yunnan Province.Total six treatment sessions were conducted every 4 wk±3 d.Before and after each treatment,facial skin characteristics were quantified using a VISIA skin detector.Skin thickness data were assessed using the ultrasound probes of the Dermalab skin detector.The Face-Q scale was used for subjective evaluation of the treatment effect by the patients.RESULTS The skin thickness of the right cheek consistently increased after each treatment session compared with baseline.The skin thickness of the left cheek significantly increased after the third through sixth treatment sessions compared with baseline.The skin thickness of the right zygomatic region increased after the second to sixth treatment sessions,whereas that of the left zygomatic region showed a significant increase after the fourth through sixth treatment sessions.The skin thickness of both temporal regions significantly increased after the fifth and sixth treatment sessions compared with baseline(P<0.05).These findings were also supported by skin ultrasound images.The feature count for the red areas and wrinkle feature count decreased following the treatment(P<0.05).VISIA assessments also revealed a decrease in the red areas after treatment.The Face-QSatisfaction with Facial Appearance Overall and Face-Q-Satisfaction with Skin scores significantly increased after each treatment session.The overall appearance of the patients improved after treatment.CONCLUSION Intradermal ColΙinjection improves photoaging,with higher patient satisfaction and fewer adverse reactions,and could be an effective treatment method for populations residing in high-altitude areas.

Atmospheric transmission algorithm for pulsed X-rays from high-altitude nuclear detonations based on scattering correction

In high-altitude nuclear detonations,the proportion of pulsed X-ray energy can exceed 70%,making it a specific monitoring signal for such events.These pulsed X-rays can be captured using a satellite-borne X-ray detector following atmospheric transmission.To quantitatively analyze the effects of different satellite detection altitudes,burst heights,and transmission angles on the physical processes of X-ray transport and energy fluence,we developed an atmospheric transmission algorithm for pulsed X-rays from high-altitude nuclear detonations based on scattering correction.The proposed method is an improvement over the traditional analytical method that only computes direct-transmission X-rays.The traditional analytical method exhibits a maximum relative error of 67.79% compared with the Monte Carlo method.Our improved method reduces this error to within 10% under the same conditions,even reaching 1% in certain scenarios.Moreover,its computation time is 48,000 times faster than that of the Monte Carlo method.These results have important theoretical significance and engineering application value for designing satellite-borne nuclear detonation pulsed X-ray detectors,inverting nuclear detonation source terms,and assessing ionospheric effects.

BLOW-UP CONDITIONS FOR A SEMILINEAR PARABOLIC SYSTEM ON LOCALLY FINITE GRAPHS

In this paper, we investigate a blow-up phenomenon for a semilinear parabolic system on locally finite graphs. Under some appropriate assumptions on the curvature condition CDE’(n,0), the polynomial volume growth of degree m, the initial values, and the exponents in absorption terms, we prove that every non-negative solution of the semilinear parabolic system blows up in a finite time. Our current work extends the results achieved by Lin and Wu (Calc Var Partial Differ Equ, 2017, 56: Art 102) and Wu (Rev R Acad Cien Serie A Mat, 2021, 115: Art 133).

Optimization of the Physical Aperture of the Parabolic Reflector Antenna

In fields like astronomy and radar technology, high-gain antennas are required for long-distance communication. Due to its relatively large gain, the use of parabolic antennas has become very popular over time, because they can easily achieve gains of above 30 dB at microwave and higher frequencies. Today, most systems’ success depends on how well the antennas perform. These antennas are available in different types and sizes. Each antenna’s effective area usually has less than the actual physical area of the antenna surface. This means that the unused area of the antenna is massive, and a waste. The aim of the research is to show that the actual physical aperture of a parabolic antenna can be reduced as much as possible to equal the effective area, as given by the antenna formula, thereby saving manufacturing costs, improve the aesthetics. In other words, the focus of this work is to experimentally show that reflector antenna can be made of smaller sizes but better performance. Measurements were taken from different positions from a parabolic antenna, the signal level measured and compared with signal levels for optimal performance.

Global Existence and Decay of Solutions for a Class of a Pseudo-Parabolic Equation with Singular Potential and Logarithmic Nonlocal Source

This article investigates the well posedness and asymptotic behavior of Neumann initial boundary value problems for a class of pseudo-parabolic equations with singular potential and logarithmic nonlinearity. By utilizing cut-off techniques and combining with the Faedo Galerkin approximation method, local solvability was established. Based on the potential well method and Hardy Sobolev inequality, derive the global existence of the solution. In addition, we also obtained the results of decay.

Improving Heat Transfer in Parabolic Trough Solar Collectors by Magnetic Nanofluids

A parabolic trough solar collector(PTSC)converts solar radiation into thermal energy.However,low thermal efficiency of PTSC poses a hindrance to the deployment of solar thermal power plants.Thermal performance of PTSC is enhanced in this study by incorporating magnetic nanoparticles into the working fluid.The circular receiver pipe,with dimensions of 66 mm diameter,2 mm thickness,and 24 m length,is exposed to uniform temperature and velocity conditions.The working fluid,Therminol-66,is supplemented with Fe3O4 magnetic nanoparticles at concentrations ranging from 1%to 4%.The findings demonstrate that the inclusion of nanoparticles increases the convective heat transfer coefficient(HTC)of the PTSC,with higher nanoparticle volume fractions leading to greater heat transfer but increased pressure drop.The thermal enhancement factor(TEF)of the PTSC is positively affected by the volume fraction of nanoparticles,both with and without a magnetic field.Notably,the scenario with a 4%nanoparticle volume fraction and a magnetic field strength of 250 G exhibits the highest TEF,indicating superior thermal performance.These findings offer potential avenues for improving the efficiency of PTSCs in solar thermal plants by introducing magnetic nanoparticles into the working fluid.

Geostructures, dynamics and risk mitigation of high-altitude and long- runout rockslides

Long-runout rockslides at high altitude could cause disaster chain in river basins and destroy towns and major infrasturctures.This paper firstly explores the initiation mechanism of high-altitude and long-runout rockslides.Two types of sliding-prone geostructure models,i.e.the fault control type in orogenic belt and the fold control type in platform area,are proposed.Then,large-scale experimental apparatus and associated numerical simulations are conducted to understanding the chain-style dynamics of rockslide-debris avalanche-debris flow.The results reveal the fragmentation effects,the rheological behaviors and the boundary layer effect of long-runout avalanche-debris flow.The dynamic character-istics of quasi-static-transition-inertia state and solid-liquid coupling in rapid movement of rockslide-debris avalanche-debris flow are investigated.Finally,the risk mitigation strategy of the non-structure and structure for resilient energy dissipation are illustrated for initiation,transition and deposition zones.The structural prevention and mitigation methods have been successfully applied to the high-altitude and long-runout rockslides in Zhouqu and Maoxian of the Wenchuan earthquake zone,as well as the other major geohazards in Qinghai-Tibet Plateau and its adjacent areas.

Investigation and simulation of parabolic trough collector with the presence of hybrid nanofluid in the finned receiver tube

The present study discusses the thermal performance of the receiver tube,which contains a wall with various fin shapes in the parabolic trough collector.Inserted fins and bulge surfaces of the inner wall of the receiver tube increase the turbulent fluid flow.In pursuance of uniform distribution of heat transfer,various fin shapes such as square-shape,circle-shape,triangle-shape,and combined square-circle shapes were inserted,examined,and compared.A study of the temperature differences and fluid flow is meaningful for this project therefore finite volume method was used to investigate heat transfer.Also,hybrid Nano-Fluid AL_(2)O_(3-)CuO,TiO_(2-)Cu,and AgMgO were applied to increase thermal diffusivity.When the combined square-circle-shaped fin was inserted,the thermal peak of fluid flow in the receiver tube was lower than the other studied fin shapes by almost 1%.Besides,the hybrid nano-fluid Ag-MgO Syltherm-oil-800 has lower thermal waste in comparison to others by more than 3%.

ALMOST SURELY TIME-SPACE INTERMITTENCY FOR THE PARABOLIC ANDERSON MODEL WITH A LOG-CORRELATED GAUSSIAN FIELD

In this paper, we consider the continuous parabolic Anderson model with a logcorrelated Gaussian field, and obtain the precise quenched long-time asymptotics and spatial asymptotics. To overcome the difficulties arising from the log-correlated Gaussian field in the proof of the lower bound of the spatial asymptotics, we first establish the relation between quenched long-time asymptotics and spatial asymptotics, and then get the lower bound of the spatial asymptotics through the lower bound of the quenched long-time asymptotics.

Glancing incidence x-ray fluorescence spectrometry based on a single-bounce parabolic capillary

Glancing incidence x-ray fluorescence spectrometry using a single-bounce parabolic capillary is proposed for the analysis of layered samples.The divergence of the x-ray beam was 0.33 mrad.In this paper,we used this instrumental setup to analyze a Si single crystal and a 50 nm HfO_(2) single-layer film deposited on a Si substrate.

Construction Technology of Warm Mix Asphalt Pavement in Cold High-Altitude Areas

With the continuous development of domestic highway construction,highway civil engineering and service level quality have attracted much attention.Good pavement quality and high-quality service make people feel comfortable and smooth when traveling.High-quality pavement can significantly reduce the probability of traffic accidents.At present,there is a direct relationship between pavement quality and pavement construction operations.Carrying out pavement construction operations in cold high-altitude areas requires a reasonable selection of construction equipment and methods.The application of warm-mix asphalt pavement construction technology can ensure pavement quality.Therefore,this paper analyzes the advantages of warm-mix technology,the environmental characteristics of cold high-altitude areas,and construction preparations,and discusses the construction technology of warm-mix asphalt pavement in cold high-altitude areas in detail,to improve the overall road quality of cold high-altitude areas.

Settlement Control Technology of High Filled Soil-Rock Embankment in Alpine and High-Altitude Areas

China's infrastructure has gradually achieved large-scale development,and transportation construction has also shifted from east to west,transitioning from plains to mountainous areas.High-fill embankments of different sizes in mountainous areas are unavoidable,and the settlement of high-fill embankments is usually the most concerned issue in high-fill projects.According to the current research of highway projects,most of the high embankments in mountainous areas are soil-rock mixed embankments or rock-filled embankments,and their post-construction settlements are directly related to construction technology and the type of filler used.In this paper,the problems in the settlement control of earth-filled embankment and related factors are analyzed in detail.The settlement control technology of high-fill embankment in high-cold and high-altitude areas is also discussed,so as to ensure the overall quality of high-fill embankment.

Entropy Formulation for Triply Nonlinear Degenerate Elliptic-Parabolic-Hyperbolic Equation with Zero-Flux Boundary Condition

In this note, we investigated existence and uniqueness of entropy solution for triply nonlinear degenerate parabolic problem with zero-flux boundary condition. Accordingly to the case of doubly nonlinear degenerate parabolic hyperbolic equation, we propose a generalization of entropy formulation and prove existence and uniqueness result without any structure condition.

IDENTIFICATION OF PARAMETERS IN SEMILINEAR PARABOLIC EQUATIONS

An optimization theoretic approach of coefficients in semilinear parabolic equation is presented. It is based on convex analysis techniques. General theorems on existence are proved in L1 setting. A necessary condition is given for the solutions of the parameter estimatioll problem.

BLOW-UP AND GLOBAL EXISTENCE FOR A COUPLED SYSTEM OF DEGENERATE PARABOLIC EQUATIONS IN A BOUNDED DOMAIN

This article deals with the conditions that ensure the blow-up phenomenon or its absence for solutions of the system ut= △u^l ＋ u^p1v^q1 and vt = △v ^m ＋ u^p2 v^q2 with homogeneous Dirichlet boundary conditions. The results depend crucially on the sign of the difference p2q1 - （l -p1）（m- q2）, the initial data, and the domain Ω.

Blow-Up Phenomena for a Class of Parabolic Systems with Time Dependent Coefficients

Blow-up phenomena for solutions of some nonlinear parabolic systems with time dependent coefficients are investigated. Both lower and upper bounds for the blow-up time are derived when blow-up occurs.

Perfectly Matched Layer for an Elastic Parabolic Equation Model in Ocean Acoustics

The perfectly matched layer(PML) is an effective technique for truncating unbounded domains with minimal spurious reflections. A fluid parabolic equation(PE) model applying PML technique was previously used to analyze the sound propagation problem in a range-dependent waveguide(Lu and Zhu, 2007). However, Lu and Zhu only considered a standard fluid PE to demonstrate the capability of the PML and did not take improved one-way models into consideration. They applied a [1/1] Padé approximant to the parabolic equation. The higher-order PEs are more accurate than standard ones when a very large angle propagation is considered. As for range-dependent problems, the techniques to handle the vertical interface between adjacent regions are mainly energy conserving and single-scattering. In this paper, the PML technique is generalized to the higher order elastic PE, as is to the higher order fluid PE. The correction of energy conserving is used in range-dependent waveguides. Simulation is made in both acoustic cases and seismo-acoustic cases. Range-independent and range-dependent waveguides are both adopted to test the accuracy and efficiency of this method. The numerical results illustrate that a PML is much more effective than an artificial absorbing layer(ABL) both in acoustic and seismo-acoustic sound propagation modeling.

A lumped mass nonconforming finite element method for nonlinear parabolic integro-differential equations on anisotropic meshes

A lumped mass approximation scheme of a low order Crouzeix-Raviart type noncon- forming triangular finite element is proposed to a kind of nonlinear parabolic integro-differential equations. The L2 error estimate is derived on anisotropic meshes without referring to the traditional nonclassical elliptic projection.

THE SPACE-TIME FINITE ELEMENT METHOD FOR PARABOLIC PROBLEMS

Adaptive space-time finite element method, continuous in space but discontinuous in time for semi-linear parabolic problems is discussed. The approach is based on a combination of finite element and finite difference techniques. The existence and uniqueness of the weak solution are proved without any assumptions on choice of the spacetime meshes. Basic error estimates in L-infinity (L-2) norm, that is maximum-norm in time, L-2-norm in space are obtained. The numerical results are given in the last part and the analysis between theoretic and experimental results are obtained.

A REMARK OF THE HLDER ESTIMATE OFSOLUTIONS OF SOME DEGENERATE PARABOLICEQUATIONS

In this paper, the Cauchy problem of the degenerate parabolic equationsis studied for some cases, and the explicit Holder estimates of the solution u with respectto x is given.