High-frequency oscillation(HFO)of gridconnected wind power generation systems(WPGS)is one of the most critical issues in recent years that threaten the safe access of WPGS to the grid.Ensuring the WPGS can damp HFO is...High-frequency oscillation(HFO)of gridconnected wind power generation systems(WPGS)is one of the most critical issues in recent years that threaten the safe access of WPGS to the grid.Ensuring the WPGS can damp HFO is becoming more and more vital for the development of wind power.The HFO phenomenon of wind turbines under different scenarios usually has different mechanisms.Hence,engineers need to acquire the working mechanisms of the different HFO damping technologies and select the appropriate one to ensure the effective implementation of oscillation damping in practical engineering.This paper introduces the general assumptions of WPGS when analyzing HFO,systematically summarizes the reasons for the occurrence of HFO in different scenarios,deeply analyses the key points and difficulties of HFO damping under different scenarios,and then compares the technical performances of various types of HFO suppression methods to provide adequate references for engineers in the application of technology.Finally,this paper discusses possible future research difficulties in the problem of HFO,as well as the possible future trends in the demand for HFO damping.展开更多
High-frequency oscillations, with periods of about 2 hours, are first identified by applying wavelet analysis to observed minutely wind speeds around the eye and eyewall of tropical cyclones(TCs). Analysis of a mode...High-frequency oscillations, with periods of about 2 hours, are first identified by applying wavelet analysis to observed minutely wind speeds around the eye and eyewall of tropical cyclones(TCs). Analysis of a model simulation of Typhoon Hagupit(2008) shows that the oscillations also occur in the TC intensity, vertical motion, convergence activity and air density around the eyewall. Sequences of oscillations in these variables follow a certain order.展开更多
There are several different nonlinearities in the turbine governor system, such as insensitivity, saturation of servo system, and frequency modulation dead band, which reduce the interaction between the governor syste...There are several different nonlinearities in the turbine governor system, such as insensitivity, saturation of servo system, and frequency modulation dead band, which reduce the interaction between the governor system and torsional oscillation, and thereby improve the torsional oscillation stability of shafts. This paper suggests intentional incorporation of appropriate nonlinearities in the governor system to improve the torsional oscillation stability of shafts.展开更多
In the present analysis torsional oscillation of a rigid disk in an infinite transversely isotropic elastic cylinder is considered. The effects of anisotropy in the stress intensity factor are shown graphically.
Variations in the high-frequency oscillations of tropical cyclones (TCs) over the western North Pacific (WNP) are studied in numerical model simulations. Power spectrum analysis of maximum wind speeds at 10 m (MW...Variations in the high-frequency oscillations of tropical cyclones (TCs) over the western North Pacific (WNP) are studied in numerical model simulations. Power spectrum analysis of maximum wind speeds at 10 m (MWS10) from an ensemble of 15 simulated TCs shows that oscillations are significant for all TCs. The magnitudes of oscillations in MWS10 are similar in the WNP and South China Sea (SCS); however, the mean of the averaged significant periods in the SCS (1.93 h) is shorter than that in the open water of the WNP (2.83 h). The shorter period in the SCS is examined through an ensemble of simulations, and a case simulation as well as a sensitivity experiment in which the continent is replaced by ocean for Typhoon Hagupit (2008). The analysis of the convergence efficiency within the boundary layer suggests that the shorter periods in the SCS are possibly due to the stronger terrain effect, which intensifies convergence through greater friction. The enhanced convergence strengthens the disturbance of the gradient and thermal wind balances, and then contributes to the shorter oscillation periods in the SCS.展开更多
In this paper,proposals in the following arcas of turbogenerator torsionaloscillation(TTO)researches in China are presented:* Concerning the focal points of TTO studies;* Concerning the modelling and data acquisition ...In this paper,proposals in the following arcas of turbogenerator torsionaloscillation(TTO)researches in China are presented:* Concerning the focal points of TTO studies;* Concerning the modelling and data acquisition of TTO;* Concerning the computation and analysis of TTO transients;* Concerning the monitoring and analyzing devices of TTO;* Concerning the countermeasures against TTO.It is concluded that researches centered on torsional oscillations caused by system dis-turbances and switching events should begin the carlier the better.展开更多
In this paper the explanation of the mechanism of high-frequency oscillation instability resulted from absorbing boundary conditions is further improved. And we analytically prove the proposition that for one dimensio...In this paper the explanation of the mechanism of high-frequency oscillation instability resulted from absorbing boundary conditions is further improved. And we analytically prove the proposition that for one dimensional discrete model of elastic wave motion, the module of reflection factor will be greater than 1 in high frequency band when artificial wave velocity is greater than 1.5 times the ratio of discrete space step to discrete time step. Based on the proof, the frequency band in which instability occurs is discussed in detail, showing such high-frequency waves are meaningless for the numerical simulation of wave motion.展开更多
To compare effect of high-frequency oscillation ventilation (HFOV) and conventional mandatory ventilation (CMV) on lung injury development in rabbit with acute respiratory distress syndrome ( ARDS). Methods Anim...To compare effect of high-frequency oscillation ventilation (HFOV) and conventional mandatory ventilation (CMV) on lung injury development in rabbit with acute respiratory distress syndrome ( ARDS). Methods Animals that underwent saline lung lavage to produce lung injury were randomized to one of the two treatment groups ( HFOV or CMV, n =6). PaCO2 was maintained between 35 -45mmHg and arterial oxygen saturation ( SaO2 ) was maintain 〉 88% by adjusting corresponding ventilator parameters. Ventilation period was 6h. Lung fluids were aspirated before and at the end of ventilation for cell analysis. Then the animals were euthanized, lung tissue was removed for wet/dry weight measurement, light and electron microscopic examination. Besults The difference of artery blood gas analyses(pH, PaO2, PaCO2 ) between HFOV and CMV was insignificant. The difference between HFOV and CMV in cytological examination of lung fluids, wet/dry weight measurement was also insignificant. But compared with CMV, HFOV not only reduced the area of lung injury, but also reduced lung injury score in light and electron microscopic examination. Conclusion When same artery blood gas analysis was obtained, HFOV significantly reduced lung injury development in ARDS animal than CMV. As a lung protection strategy, HFOV can be used in the treatment of ARDS.展开更多
Torsional vibration of roller oscillating tooth gear drive (ROTGD) is studied in this paper. On the basis of conservation law for kinetic energy and potential energy, the mathematical expressions are developed which d...Torsional vibration of roller oscillating tooth gear drive (ROTGD) is studied in this paper. On the basis of conservation law for kinetic energy and potential energy, the mathematical expressions are developed which describe transformation of moment of inertia of inertial components into input shaft. Also, the formula is derived which expresses transformation of contact stiffness of elastic components into input shaft torsional stiffness. Besides, torsional vibration model of ROTGD is presented by using the transfer matrix method, and natural frequencies and vibration mode shapes are determined. Eventually, an example is given.展开更多
Nowadays with the improvement in the degree of emphasis on new energy, the wind power system has developed more and more rapidly over the world. Usually the wind plants are located in the remote areas which are far fr...Nowadays with the improvement in the degree of emphasis on new energy, the wind power system has developed more and more rapidly over the world. Usually the wind plants are located in the remote areas which are far from the load centers. Generally series compensated AC transmission and high voltage DC transmission are made use of to improve the transmission capacity as two main effective ways which can solve the problem of large scale wind power transmission. The paper describes the three kinds of impact varieties and impact mechanisms in the sub-synchronous oscillation phenomena of wind power system based on doubly fed induction generator (DFIG) wind generators. At last, we point out the important problem that should be stressed in the wind power system.展开更多
Using a simple damped slab model, it was possible to show that a local wind induced 88% (15 of 17) of the near-inertial oscillations (NIO) observed in the mixed layer near the east coast of Korea from 1999 to 2004...Using a simple damped slab model, it was possible to show that a local wind induced 88% (15 of 17) of the near-inertial oscillations (NIO) observed in the mixed layer near the east coast of Korea from 1999 to 2004. The model, however, overestimated the energy level in about two-thirds of the simulated cases, because the slab model was forced with winds whose characteristic period was shorter than the damping time scale of the model at 1.5 d. At the observation site, due to typhoons and orographic effects, high-frequency wind forcing is quite common, as is the overestimation of the energy level in the slab model results. In short, a simple slab model with a damping time-scale of about 1.5 d would be enough to show that the local wind was the main energy source of the near-inertial energy in this area, but the model could not be used to accurately estimate the amount of the work done by the wind to the mixed layer.展开更多
This paper proposes a powerful subsynchronous component based (SSC) controller to mitigate the subsynchronous resonance (SSR) with statics synchronous series compensator (SSSC). The mitigation of SSR is achieved by in...This paper proposes a powerful subsynchronous component based (SSC) controller to mitigate the subsynchronous resonance (SSR) with statics synchronous series compensator (SSSC). The mitigation of SSR is achieved by increasing the network damping at those frequencies which are close to the torsional frequency of the turbine-generator shaft. The increase of network damping is done by the extraction of subsynchronous component of voltage and current from the measured signal of the system. From the knowledge of subsynchronous components, a series voltage is injected by SSSC into the transmission line to make the subsynchronous current to zero which is the main cause of turbine oscillations. To analyze the effectiveness of the proposed control scheme, IEEE first benchmark model has taken. The results show the accuracy of the proposed control scheme to mitigate the Torque amplification of SSR.展开更多
Background:The combination of high-frequency oscillations(HFOs)with single-mode imaging methods has been proved useful in identifying epileptogenic zones,whereas few studies have examined HFOs combined with multimodal...Background:The combination of high-frequency oscillations(HFOs)with single-mode imaging methods has been proved useful in identifying epileptogenic zones,whereas few studies have examined HFOs combined with multimodal imaging methods.The aim of this study was to evaluate the prognostic value of ripples,an HFO subtype with a frequency of 80 to 200 Hz is combined with multimodal imaging methods in predicting epilepsy surgery outcome.Methods:HFOs were analyzed in 21 consecutive medically refractory epilepsy patients who underwent epilepsy surgery.All patients underwent positron emission tomography(PET)and deep electrode implantation for stereo-electroencephalography(SEEG);11 patients underwent magnetoencephalography(MEG).Sensitivity,specificity,positive predictive value,negative predictive value,and accuracy in predicting surgical outcome were calculated for ripples combined with PET,MEG,both PET and MEG,and PET combined with MEG.Kaplan-Meier survival analyses were conducted in each group to estimate prognostic value.Results:The study included 13 men and 8 women.Accuracy for ripples,PET,and MEG alone in predicting surgical outcome was 42.9%,42.9%,and 81.8%,respectively.Accuracy for ripples combined with PET and MEG was the highest.Resection of regions identified by ripples,MEG dipoles,and combined PET findings was significantly associated with better surgical outcome(P<0.05).Conclusions:Intracranial electrodes are essential to detect regions which generate ripples and to remove these areas which indicate good surgical outcome for medically intractable epilepsy.With the assistance of presurgical noninvasive imaging examinations,PET and MEG,for example,the SEEG electrodes would identify epileptogenic regions more effectively.展开更多
A symmetric disc-shaped torsion pendulum was designed to study the nonlinear effects of the torsion fiber. It was showed that the period of the pendulum decreases with the amplitude of the oscillation. Determination o...A symmetric disc-shaped torsion pendulum was designed to study the nonlinear effects of the torsion fiber. It was showed that the period of the pendulum decreases with the amplitude of the oscillation. Determination of the unperturbed period through a fit to measured data of the period variation with amplitude shows that this systematic error in the measurement of Newtonian gravitational constant G by the time-of-swing method can be reduced by an order of the magnitude at least.展开更多
Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations(HFOs,>80 Hz)and the epileptogenic zone,suggesting that HFOs can be a po...Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations(HFOs,>80 Hz)and the epileptogenic zone,suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis.This consensus includes the definition and standard detection techniques of HFOs,the localizing value of pathological HFOs for epileptic foci,and different ways to distinguish physiological from epileptic HFOs.The latest clinical applications of HFOs in epilepsy and the related findings are also discussed.HFOs will advance our understanding of the pathophysiology of epilepsy.展开更多
High-frequency oscillations(HFOs)in the electroencephalography(EEG)have been extensively investigated as a potential biomarker of epileptogenic zones.The understanding of the role of HFOs in epilepsy has been advanced...High-frequency oscillations(HFOs)in the electroencephalography(EEG)have been extensively investigated as a potential biomarker of epileptogenic zones.The understanding of the role of HFOs in epilepsy has been advanced considerably over the past decade,and the use of scalp EEG facilitates recordings of HFOs.HFOs were initially applied in large scale in epilepsy surgery and are now being utilized in other applications.In this review,we summarize applications of HFOs in 3 subtopics:(1)HFOs as biomarkers to evaluate epilepsy treatment outcome;(2)HFOs as biomarkers to measure seizure propensity;(3)HFOs as biomarkers to reflect the pathological severity of epilepsy.Nevertheless,knowledge regarding the above clinical applications of HFOs remains limited at present.Further validation through prospective studies is required for its reliable application in the clinical management of individual epileptic patients.展开更多
基金supported in part by the Fundamental Research Funds for the Central Universities under Grant 2682023CX019National Natural Science Foundation of China under Grant U23B6007 and Grant 52307141Sichuan Science and Technology Program under Grant 2024NSFSC0115。
文摘High-frequency oscillation(HFO)of gridconnected wind power generation systems(WPGS)is one of the most critical issues in recent years that threaten the safe access of WPGS to the grid.Ensuring the WPGS can damp HFO is becoming more and more vital for the development of wind power.The HFO phenomenon of wind turbines under different scenarios usually has different mechanisms.Hence,engineers need to acquire the working mechanisms of the different HFO damping technologies and select the appropriate one to ensure the effective implementation of oscillation damping in practical engineering.This paper introduces the general assumptions of WPGS when analyzing HFO,systematically summarizes the reasons for the occurrence of HFO in different scenarios,deeply analyses the key points and difficulties of HFO damping under different scenarios,and then compares the technical performances of various types of HFO suppression methods to provide adequate references for engineers in the application of technology.Finally,this paper discusses possible future research difficulties in the problem of HFO,as well as the possible future trends in the demand for HFO damping.
基金supported by the National Natural Science Foundation of China (Grant Nos. 41375050, 41405048 and 41205032)the China National Basic Research Program (Grant Nos. 2011CB403500 and 2014CB953904)
文摘High-frequency oscillations, with periods of about 2 hours, are first identified by applying wavelet analysis to observed minutely wind speeds around the eye and eyewall of tropical cyclones(TCs). Analysis of a model simulation of Typhoon Hagupit(2008) shows that the oscillations also occur in the TC intensity, vertical motion, convergence activity and air density around the eyewall. Sequences of oscillations in these variables follow a certain order.
文摘There are several different nonlinearities in the turbine governor system, such as insensitivity, saturation of servo system, and frequency modulation dead band, which reduce the interaction between the governor system and torsional oscillation, and thereby improve the torsional oscillation stability of shafts. This paper suggests intentional incorporation of appropriate nonlinearities in the governor system to improve the torsional oscillation stability of shafts.
文摘In the present analysis torsional oscillation of a rigid disk in an infinite transversely isotropic elastic cylinder is considered. The effects of anisotropy in the stress intensity factor are shown graphically.
基金supported by the National Natural Science Foundation of China (Grant Nos. 41405048, 41675043, 41375050, 41205032 and 41775094)Independent Research Project Program of State Key Laboratory of Tropical Oceanography (Grant No. LTOZZ1603)
文摘Variations in the high-frequency oscillations of tropical cyclones (TCs) over the western North Pacific (WNP) are studied in numerical model simulations. Power spectrum analysis of maximum wind speeds at 10 m (MWS10) from an ensemble of 15 simulated TCs shows that oscillations are significant for all TCs. The magnitudes of oscillations in MWS10 are similar in the WNP and South China Sea (SCS); however, the mean of the averaged significant periods in the SCS (1.93 h) is shorter than that in the open water of the WNP (2.83 h). The shorter period in the SCS is examined through an ensemble of simulations, and a case simulation as well as a sensitivity experiment in which the continent is replaced by ocean for Typhoon Hagupit (2008). The analysis of the convergence efficiency within the boundary layer suggests that the shorter periods in the SCS are possibly due to the stronger terrain effect, which intensifies convergence through greater friction. The enhanced convergence strengthens the disturbance of the gradient and thermal wind balances, and then contributes to the shorter oscillation periods in the SCS.
文摘In this paper,proposals in the following arcas of turbogenerator torsionaloscillation(TTO)researches in China are presented:* Concerning the focal points of TTO studies;* Concerning the modelling and data acquisition of TTO;* Concerning the computation and analysis of TTO transients;* Concerning the monitoring and analyzing devices of TTO;* Concerning the countermeasures against TTO.It is concluded that researches centered on torsional oscillations caused by system dis-turbances and switching events should begin the carlier the better.
基金Basic Scientific Research-related Project from Institute of Engineering Mechanics (01180001 and 2007C01)
文摘In this paper the explanation of the mechanism of high-frequency oscillation instability resulted from absorbing boundary conditions is further improved. And we analytically prove the proposition that for one dimensional discrete model of elastic wave motion, the module of reflection factor will be greater than 1 in high frequency band when artificial wave velocity is greater than 1.5 times the ratio of discrete space step to discrete time step. Based on the proof, the frequency band in which instability occurs is discussed in detail, showing such high-frequency waves are meaningless for the numerical simulation of wave motion.
文摘To compare effect of high-frequency oscillation ventilation (HFOV) and conventional mandatory ventilation (CMV) on lung injury development in rabbit with acute respiratory distress syndrome ( ARDS). Methods Animals that underwent saline lung lavage to produce lung injury were randomized to one of the two treatment groups ( HFOV or CMV, n =6). PaCO2 was maintained between 35 -45mmHg and arterial oxygen saturation ( SaO2 ) was maintain 〉 88% by adjusting corresponding ventilator parameters. Ventilation period was 6h. Lung fluids were aspirated before and at the end of ventilation for cell analysis. Then the animals were euthanized, lung tissue was removed for wet/dry weight measurement, light and electron microscopic examination. Besults The difference of artery blood gas analyses(pH, PaO2, PaCO2 ) between HFOV and CMV was insignificant. The difference between HFOV and CMV in cytological examination of lung fluids, wet/dry weight measurement was also insignificant. But compared with CMV, HFOV not only reduced the area of lung injury, but also reduced lung injury score in light and electron microscopic examination. Conclusion When same artery blood gas analysis was obtained, HFOV significantly reduced lung injury development in ARDS animal than CMV. As a lung protection strategy, HFOV can be used in the treatment of ARDS.
文摘Torsional vibration of roller oscillating tooth gear drive (ROTGD) is studied in this paper. On the basis of conservation law for kinetic energy and potential energy, the mathematical expressions are developed which describe transformation of moment of inertia of inertial components into input shaft. Also, the formula is derived which expresses transformation of contact stiffness of elastic components into input shaft torsional stiffness. Besides, torsional vibration model of ROTGD is presented by using the transfer matrix method, and natural frequencies and vibration mode shapes are determined. Eventually, an example is given.
文摘Nowadays with the improvement in the degree of emphasis on new energy, the wind power system has developed more and more rapidly over the world. Usually the wind plants are located in the remote areas which are far from the load centers. Generally series compensated AC transmission and high voltage DC transmission are made use of to improve the transmission capacity as two main effective ways which can solve the problem of large scale wind power transmission. The paper describes the three kinds of impact varieties and impact mechanisms in the sub-synchronous oscillation phenomena of wind power system based on doubly fed induction generator (DFIG) wind generators. At last, we point out the important problem that should be stressed in the wind power system.
基金The Agency for Defense Development under contract Nos 609-83-01532,UD000008BD and UD970022ADKorea Institute of Science and Technology Evaluation and Planning under contract No.2000-N-NL-01-C-012+3 种基金the Korean Ministry of Environments under contract No.121-041-033Korean Ministry of Education under the BK21 ProgramKorea Research Foundation under the Free-doctoral scholars programKorean Ministry of Oceans and Fisheries under the projects"Development of Korea Operational Oceanographic System(KOOS)"and"Development of Technology for CO2Marine Geological Storage"
文摘Using a simple damped slab model, it was possible to show that a local wind induced 88% (15 of 17) of the near-inertial oscillations (NIO) observed in the mixed layer near the east coast of Korea from 1999 to 2004. The model, however, overestimated the energy level in about two-thirds of the simulated cases, because the slab model was forced with winds whose characteristic period was shorter than the damping time scale of the model at 1.5 d. At the observation site, due to typhoons and orographic effects, high-frequency wind forcing is quite common, as is the overestimation of the energy level in the slab model results. In short, a simple slab model with a damping time-scale of about 1.5 d would be enough to show that the local wind was the main energy source of the near-inertial energy in this area, but the model could not be used to accurately estimate the amount of the work done by the wind to the mixed layer.
文摘This paper proposes a powerful subsynchronous component based (SSC) controller to mitigate the subsynchronous resonance (SSR) with statics synchronous series compensator (SSSC). The mitigation of SSR is achieved by increasing the network damping at those frequencies which are close to the torsional frequency of the turbine-generator shaft. The increase of network damping is done by the extraction of subsynchronous component of voltage and current from the measured signal of the system. From the knowledge of subsynchronous components, a series voltage is injected by SSSC into the transmission line to make the subsynchronous current to zero which is the main cause of turbine oscillations. To analyze the effectiveness of the proposed control scheme, IEEE first benchmark model has taken. The results show the accuracy of the proposed control scheme to mitigate the Torque amplification of SSR.
文摘Background:The combination of high-frequency oscillations(HFOs)with single-mode imaging methods has been proved useful in identifying epileptogenic zones,whereas few studies have examined HFOs combined with multimodal imaging methods.The aim of this study was to evaluate the prognostic value of ripples,an HFO subtype with a frequency of 80 to 200 Hz is combined with multimodal imaging methods in predicting epilepsy surgery outcome.Methods:HFOs were analyzed in 21 consecutive medically refractory epilepsy patients who underwent epilepsy surgery.All patients underwent positron emission tomography(PET)and deep electrode implantation for stereo-electroencephalography(SEEG);11 patients underwent magnetoencephalography(MEG).Sensitivity,specificity,positive predictive value,negative predictive value,and accuracy in predicting surgical outcome were calculated for ripples combined with PET,MEG,both PET and MEG,and PET combined with MEG.Kaplan-Meier survival analyses were conducted in each group to estimate prognostic value.Results:The study included 13 men and 8 women.Accuracy for ripples,PET,and MEG alone in predicting surgical outcome was 42.9%,42.9%,and 81.8%,respectively.Accuracy for ripples combined with PET and MEG was the highest.Resection of regions identified by ripples,MEG dipoles,and combined PET findings was significantly associated with better surgical outcome(P<0.05).Conclusions:Intracranial electrodes are essential to detect regions which generate ripples and to remove these areas which indicate good surgical outcome for medically intractable epilepsy.With the assistance of presurgical noninvasive imaging examinations,PET and MEG,for example,the SEEG electrodes would identify epileptogenic regions more effectively.
基金the National Natural Science Foundation of China under Grant Nos.19425008 and 19835040.
文摘A symmetric disc-shaped torsion pendulum was designed to study the nonlinear effects of the torsion fiber. It was showed that the period of the pendulum decreases with the amplitude of the oscillation. Determination of the unperturbed period through a fit to measured data of the period variation with amplitude shows that this systematic error in the measurement of Newtonian gravitational constant G by the time-of-swing method can be reduced by an order of the magnitude at least.
基金the National Key R&D Program(No.2018YFC1314500)the National Natural Science Foundation of China(No.81701297,81801124).
文摘Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations(HFOs,>80 Hz)and the epileptogenic zone,suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis.This consensus includes the definition and standard detection techniques of HFOs,the localizing value of pathological HFOs for epileptic foci,and different ways to distinguish physiological from epileptic HFOs.The latest clinical applications of HFOs in epilepsy and the related findings are also discussed.HFOs will advance our understanding of the pathophysiology of epilepsy.
基金supported by grants from the National Key R&D Program of China(2017YFC1307500 to QW)the Capital Health Research and Development of Special Program(2016-1-2011 and 2020-1-2013 to QW)+2 种基金the Beijing-Tianjin-Hebei Cooperative Basic Research Program(H2018206435 to QW)the Beijing Natural Science Foundation(Z200024 to YGW and QW)the National Natural Science Foundation of China(81801280 to GR,81601126 to JR).
文摘High-frequency oscillations(HFOs)in the electroencephalography(EEG)have been extensively investigated as a potential biomarker of epileptogenic zones.The understanding of the role of HFOs in epilepsy has been advanced considerably over the past decade,and the use of scalp EEG facilitates recordings of HFOs.HFOs were initially applied in large scale in epilepsy surgery and are now being utilized in other applications.In this review,we summarize applications of HFOs in 3 subtopics:(1)HFOs as biomarkers to evaluate epilepsy treatment outcome;(2)HFOs as biomarkers to measure seizure propensity;(3)HFOs as biomarkers to reflect the pathological severity of epilepsy.Nevertheless,knowledge regarding the above clinical applications of HFOs remains limited at present.Further validation through prospective studies is required for its reliable application in the clinical management of individual epileptic patients.