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Offshore high-grade limemud resources of west coast of India:Economic potential and industrial applications
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作者 Anil Kumar Adukadukkam Rachna Pillai Mamatha Puthiyathara Kanakamma 《Deep Underground Science and Engineering》 2024年第2期163-170,共8页
Limestone is one of the essential raw materials in the cement,paint,steel,ceramic,glass,chemical,pharmaceutical,paper,and fertilizer industries.In India,only 8%of the limestone resources are placed under the reserve c... Limestone is one of the essential raw materials in the cement,paint,steel,ceramic,glass,chemical,pharmaceutical,paper,and fertilizer industries.In India,only 8%of the limestone resources are placed under the reserve category,of which 97%is of cement grade.Thus,India depends on imports to bridge the demand‐supply gap of steel,blast furnace,and chemical‐grade limestone.Efforts of Geological Survey of India(GSI)to locate alternate sources for limestone led to the discovery of enormous quantities of carbonate minerals called limemud from the continental shelf margin of the west coast of India.GSI carried out systematic studies to explore the nature of the disposition,quality,quantity,and suitability of the offshore limemud for various industrial applications.A preliminary estimate of resources using high‐resolution subbottom profiling and sediment core sample studies established the occurrence of more than 172 billion tonnes of high‐grade(The content of CaCO3 is greater than 80 wt%)limemud in 0.4–28.0m thick stratified sediment layers spread over an area of 18000 km2.Chemical,physical,mineralogical,beneficiation,and agglomeration studies found the offshore limemud as a potential replacement for limestone in the cement,filler,blast furnace,steel melting shop,lime production,paint,and Grade‐I steel industries.An assessment of mining and transportation costs indicates that the offshore limemud(USD 5–6/ton)is more cost‐effective than that imported from other countries(USD16‐18/ton).With several advantageous factors like low impurity,mode of occurrence in overburden‐free stratified form,fine‐grained slurry nature,and shallow water depth,sustainable mining of offshore limemud could be a future reality with controllable technological,economic,and environmental challenges. 展开更多
关键词 BENEFICIATION industrial grade offshore limemud west coast of India
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High-grade pancreatic intraepithelial neoplasia diagnosed based on changes in magnetic resonance cholangiopancreatography findings:A case report 被引量:2
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作者 Nao Furuya Atsushi Yamaguchi +13 位作者 Naohiro Kato Syuhei Sugata Takuro Hamada Takeshi Mizumoto Yuzuru Tamaru Ryusaku Kusunoki Toshio Kuwai Hirotaka Kouno Kazuya Kuraoka Yoshiyuki Shibata Sho Tazuma Takeshi Sudo Hiroshi Kohno Shiro Oka 《World Journal of Clinical Cases》 SCIE 2024年第8期1487-1496,共10页
BACKGROUND High-grade pancreatic intraepithelial neoplasia(PanIN)exhibits no mass and is not detected by any examination modalities.However,it can be diagnosed by pancreatic juice cytology from indirect findings.Most ... BACKGROUND High-grade pancreatic intraepithelial neoplasia(PanIN)exhibits no mass and is not detected by any examination modalities.However,it can be diagnosed by pancreatic juice cytology from indirect findings.Most previous cases were diagnosed based on findings of a focal stricture of the main pancreatic duct(MPD)and caudal MPD dilatation and subsequent pancreatic juice cytology using endoscopic retrograde cholangiopancreatography(ERCP).We experienced a case of high-grade PanIN with an unclear MPD over a 20-mm range,but without caudal MPD dilatation on magnetic resonance cholangiopancreatography(MRCP).CASE SUMMARY A 60-year-old female patient underwent computed tomography for a follow-up of uterine cancer post-excision,which revealed pancreatic cysts.MRCP revealed an unclear MPD of the pancreatic body at a 20-mm length without caudal MPD dilatation.Thus,course observation was performed.After 24 mo,MRCP revealed an increased caudal MPD caliber and a larger pancreatic cyst.We performed ERCP and detected atypical cells suspected of adenocarcinoma by serial pancreatic juice aspiration cytology examination.We performed a distal pancreatectomy and obtained a histopathological diagnosis of high-grade PanIN.Pancreatic parenchyma invasion was not observed,and curative resection was achieved.CONCLUSION High-grade Pan-IN may cause MPD narrowing in a long range without caudal MPD dilatation. 展开更多
关键词 Pancreatic cancer Pancreatic intraepithelial neoplasm high-grade pancreatic intraepithelial neoplasm Magnetic resonance cholangiopancreatography Carcinoma in situ Case report
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Bulk geochemistry,Rb-Sr,Sm-Nd,and stable O-H isotope systematics of the Metzimevin high-grade iron ore deposit,Mbalam iron ore district,southern Cameroon
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作者 Samndong Cyril Tufoin Cheo Emmanuel Suh +1 位作者 Tabod Charles Tabod George Lemewihbwen Ngiamte 《Acta Geochimica》 EI CAS CSCD 2024年第4期677-706,共30页
Bulk geochemistry,Sr,Nd,and O-H isotope systematics are reported for the first time on banded iron formation(BIF)-hosted high-grade iron ore at the northwestern segment of Congo Craton(CC).Located in Mbalam iron ore d... Bulk geochemistry,Sr,Nd,and O-H isotope systematics are reported for the first time on banded iron formation(BIF)-hosted high-grade iron ore at the northwestern segment of Congo Craton(CC).Located in Mbalam iron ore district,Southern Cameroon,Metzimevin iron ore deposit is a hematite-magnetite BIF system,dominated by SiO_(2)+Fe_(2)O_(3)(97.1 to 99.84 wt%),with low concentrations of clastic elements e.g.,Al_(2)O_(3),TiO_(2),and HFSE,depicting a nearly pure chemical precipitate.The REE+Y signature of the iron deposit displays strong positive Eu anomaly,strong negative Ce anomaly,and chondritic to superchondritic Y/Ho ratios,suggestive of formation by mixed seawater-high temperature hydrothermal fluids in oxidising environment.The^(87)Sr/^(86)Sr ratios of the BIF are higher than the maximum^(87)Sr/^(86)Sr evolution curves for all Archean reservoirs(bulk silicate earth,Archean crust and Archean seawater),indicating involvement of continentally-derived components during BIF formation and alteration.TheƐ_(Nd)(t)(+2.26 to+3.77)and Nd model age indicate that chemical constituents for the BIF were derived from undifferentiated crustal source,between 3.002 and 2.88 Ga.The variable and diverse O and H isotope data(−1.9‰to 17.3‰and−57‰to 136‰respectively)indicate that the Metzimevin iron ore formed initially from magmatic plumes and later enriched by magmatic-metamorphic-modified meteoric fluids.Mass balance calculations indicate mineralisation by combined leaching and precipitation,with an average iron enrichment factor of>2.67 and SiO_(2)depletion factor of>0.99.This is associated with an overall volume reduction of 28.27%,reflecting net leaching and volume collapse of the BIF protholith. 展开更多
关键词 Bulk geochemistry RB-SR SM-ND Mitzimevin high-grade iron ore
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Management of retroperitoneal high-grade serous carcinoma of unknown origin:A case report
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作者 Wen-Lin Hsieh Dah-Ching Ding 《World Journal of Clinical Cases》 SCIE 2024年第6期1190-1195,共6页
BACKGROUND Retroperitoneal high-grade serous carcinoma(HGSC)of unknown origin is a sporadic tumor that can originate from ovarian cancer.Herein,we report the case of a woman with retroperitoneal HGSC of unknown origin... BACKGROUND Retroperitoneal high-grade serous carcinoma(HGSC)of unknown origin is a sporadic tumor that can originate from ovarian cancer.Herein,we report the case of a woman with retroperitoneal HGSC of unknown origin and describe how she was diagnosed and treated.CASE SUMMARY A 71-year-old female presented with the tumor marker CA125 elevated to 1041.9 U/mL upon a regular health examination.Computed tomography revealed retroperitoneal lymph node enlargement.Subsequently,positron emission tomography scanning revealed lesions with increased F-18 fluorodeoxyglucose uptake at the nodes.As a result,she underwent laparoscopic lymph node resection,and pathology revealed metastatic adenocarcinoma with CK7(+),PAX8(+),WT1(+),PR(-),and p53 mutational loss of expression,indicating that the origin may be from the adnexa.The patient was admitted to our ward and underwent laparoscopic staging;however,the pathological results were negative.Under the suspicion of retroperitoneal HGSC of unknown origin,chemotherapy and targeted therapy were initiated.Tumor marker levels decreased after treatment.CONCLUSION We present a case of HGSC of unknown origin managed using retroperitoneal lymphadenectomy,staging surgery,chemotherapy,and targeted therapy. 展开更多
关键词 high-grade serous carcinoma RETROPERITONEUM ORIGIN Chemotherapy Lymph node Case report
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Characteristics and risk factor analyses of high-grade intraepithelial neoplasia in older patients with colorectal polyps
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作者 Xin Zhang Ying Wang +2 位作者 Tong Zhu Jian Ge Jun-Hua Yuan 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第10期4129-4137,共9页
BACKGROUND According to the degree of intradermal neoplasia in the colorectal exhalation,it can be divided into two grades:Low-grade intraepithelial neoplasia(LGIN)and high-grade intraepithelial neoplasia(HGIN).Curren... BACKGROUND According to the degree of intradermal neoplasia in the colorectal exhalation,it can be divided into two grades:Low-grade intraepithelial neoplasia(LGIN)and high-grade intraepithelial neoplasia(HGIN).Currently,it is difficult to accurately diagnose LGIN and HGIN through imaging,and clinical diagnosis depends on postoperative histopathological diagnosis.A more accurate method for evaluating HGIN preoperatively is urgently needed in the surgical treatment and nursing intervention of colorectal polyps.AIM To explore the characteristics and risk factors of HGIN in older patients with colorectal polyps.METHODS We selected 84 older patients diagnosed with HGIN as the HGIN group(n=95 colonic polyps)and 112 older patients diagnosed with LGIN as the LGIN group(n=132 colonic polyps)from Shandong Provincial Hospital Affiliated to Shandong First Medical University.The endoscopic features,demographic characteristics,and clinical manifestations of the two patient groups were compared,and a logistic regression model was used to analyze the risk factors for HGIN in these patients.RESULTS The HGIN group was older and had a higher number of sigmoid colon polyps,rectal polyps,pedunculated polyps,polyps≥1.0 cm in size,polyps with surface congestion,polyps with surface depression,and polyps with villous/tubular adenomas,a higher proportion of patients with diabetes and a family history of colorectal cancer,patients who experienced rectal bleeding or occult blood,patients with elevated carcinoembryonic antigen(CEA)and cancer antigen 199(CA199),and lower nutritional levels and higher frailty levels.The polyp location(in the sigmoid colon or rectum),polyp diameter(≥1.0 cm),pathological diagnosis of(villous/tubular adenoma),family history of colorectal cancer,rectal bleeding or occult blood,elevated serum CEA and CA199 levels,lower nutritional levels and higher frailty levels also are independent risk factors for HGIN.CONCLUSION The occurrence of high-grade neoplastic transformation in colorectal polyps is closely associated with their location,size,villous/tubular characteristics,family history,elevated levels of tumor markers,and lower nutritional levels and higher frailty levels. 展开更多
关键词 ELDERLY Colorectal polyps high-grade intraepithelial neoplasia Low-grade intraepithelial neoplasia Risk factors
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High-grade serous carcinoma of the fallopian tube in a young woman with chromosomal 4q abnormality:A case report
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作者 Kai-Cheng Zhang Shao-Yin Chu Dah-Ching Ding 《World Journal of Clinical Cases》 SCIE 2024年第18期3539-3547,共9页
BACKGROUND Few studies have reported an association between an increased risk of acquiring cancers and survival in patients with 4q deletion syndrome.This study presents a rare association between chromosome 4q abnorm... BACKGROUND Few studies have reported an association between an increased risk of acquiring cancers and survival in patients with 4q deletion syndrome.This study presents a rare association between chromosome 4q abnormalities and fallopian tube highgrade serous carcinoma(HGSC)in a young woman.CASE SUMMARY A 35-year-old woman presented with acute dull abdominal pain and a known chromosomal abnormality involving 4q13.3 duplication and 4q23q24 deletion.Upon arrival at the emergency room,her abdomen appeared ovoid and distended with palpable shifting dullness.Ascites were identified through abdominal ultrasound,and computed tomography revealed an omentum cake and an enlarged bilateral adnexa.Blood tests showed elevated CA-125 levels.Paracentesis was conducted,and immunohistochemistry indicated that the cancer cells favored an ovarian origin,making us suspect ovarian cancer.The patient underwent debulking surgery,which led to a diagnosis of stage IIIC HGSC of the fallopian tube.Subsequently,the patient received adjuvant chemotherapy with carboplatin and paclitaxel,resulting in stable current condition.CONCLUSION This study demonstrates a rare correlation between a chromosome 4q abnormality and HGSC.UBE2D3 may affect crucial cancer-related pathways,including P53,BRCA,cyclin D,and tyrosine kinase receptors,thereby possibly contributing to cancer development.In addition,ADH1 and DDIT4 may be potential influencers of both carcinogenic and therapeutic responses. 展开更多
关键词 high-grade serous carcinoma Fallopian tube Young age Chromosomal abnormality Mental retardation AGING Case report
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Transformation of marginal zone lymphoma into high-grade B-cell lymphoma expressing terminal deoxynucleotidyl transferase:A case report
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作者 Zhi-Min Fan Dao-Lei Wu +4 位作者 Neng-Wen Xu Li Ye Li-Ping Yan Lin-Jie Li Jun-Yu Zhang 《World Journal of Clinical Cases》 SCIE 2024年第15期2655-2663,共9页
BACKGROUND High-grade B-cell lymphoma(HGBL)is an unusual malignancy that includes myelocytomatosis viral oncogene(MYC),B-cell lymphoma-2(BCL-2),and/or BCL-6 rearrangements,termed double-hit or triple-hit lymphomas,and... BACKGROUND High-grade B-cell lymphoma(HGBL)is an unusual malignancy that includes myelocytomatosis viral oncogene(MYC),B-cell lymphoma-2(BCL-2),and/or BCL-6 rearrangements,termed double-hit or triple-hit lymphomas,and HGBL-not otherwise specific(HGBL-NOS),which are morphologically characteristic of HGBL but lack MYC,BCL-2,or BCL-6 rearrangements.HGBL is partially transformed by follicular lymphoma and other indolent lymphoma,with few cases of marginal zone lymphoma(MZL)transformation.HGBL often has a poor prognosis and intensive therapy is currently mainly advocated,but there is no good treatment for these patients who cannot tolerate chemotherapy.CASE SUMMARY We reported a case of MZL transformed into HGBL-NOS with TP53 mutation and terminal deoxynucleotidyl transferase expression.Gene analysis revealed the gene expression profile was identical in the pre-and post-transformed tissues,suggesting that the two diseases are homologous,not secondary tumors.The chemotherapy was ineffective and the side effect was severe,so we tried combination therapy including venetoclax and obinutuzumab.The patient tolerated treatment well,and reached partial response.The patient had recurrence of hepatocellular carcinoma and died of multifunctional organ failure.He survived for 12 months after diagnosis.CONCLUSION Venetoclax combined with obinutuzumab might improve the survival in some HGBL patients,who are unsuitable for chemotherapy. 展开更多
关键词 Marginal zone lymphoma high-grade B-cell lymphoma Terminal deoxynucleotidyl transferase Venetoclax TP53 mutation Case report
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Development Level and Dynamic Analysis of the Integration of Three Rural Industries in the Context of Rural Revitalization
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作者 Longling LI Zijian LONG 《Asian Agricultural Research》 2024年第9期1-6,10,共7页
As a key measure to comprehensively promote the strategy of rural revitalization,especially in the field of industrial prosperity,the integration of rural three industries is of great strategic significance.In this st... As a key measure to comprehensively promote the strategy of rural revitalization,especially in the field of industrial prosperity,the integration of rural three industries is of great strategic significance.In this study,entropy method and TOPSIS method were employed to calculate the comprehensive evaluation index of integration of three industries and the ideal development value respectively.The development status of integration of three rural industries was systematically evaluated,and the development trend of different regions was compared and analyzed.The results indicate that the development index of integration of three industries showed a steady growth trend,among which the development level of Jiangsu Province ranked first,followed by Hubei Province,while the development level of Shaanxi Province was relatively low.When analyzing the Level I indicators of integration of three rural industries,the contribution of industrial integration behavior exceeded the performance of industrial integration.Among the behavioral indicators of industrial integration,the weight of agricultural multi-functionality and service integration was relatively large,which plays a significant role in promoting the development of integration of three rural industries.The scores and growth rates of Jiangsu Province in increasing farmers income,increasing agricultural production and rural economic development were higher than those of other regions,while Shaanxi Province still had a certain gap in rural industrial integration indicators compared with Jiangsu Province and Hubei Province.In view of this,we came up with some strategic recommendations for further promoting the development of integration of three rural industries. 展开更多
关键词 INTEGRATION of three industries Entropy METHOD TOPSIS METHOD RURAL REVITALIZATION
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Digitalization Enables Cultural,Commercial and Tourism Industries to Explore the Global Market
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作者 Zhao Ailing 《China's Foreign Trade》 2024年第3期52-54,共3页
The recent 2024 National Tour ism Development Conference has clearly pointed out that China’s tourism industry has grown into the world’s largest domestic tourism market and has become an important destination in th... The recent 2024 National Tour ism Development Conference has clearly pointed out that China’s tourism industry has grown into the world’s largest domestic tourism market and has become an important destination in the international tourism sector,marking the rise of the tourism industry as a strategic pillar industry for the country. 展开更多
关键词 Market TOURISM industry
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Science and Technology Promotion Policies of Strategic Emerging Industries in Anhui Province
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作者 Wenming SUN 《Meteorological and Environmental Research》 2024年第4期5-7,共3页
In recent years,based on advantages of industry,market,science and technology and other development environment,strategic emerging industries in Anhui Province are developing rapidly,and emerging industries such as ne... In recent years,based on advantages of industry,market,science and technology and other development environment,strategic emerging industries in Anhui Province are developing rapidly,and emerging industries such as new energy,new materials,new generation of information technology occupy an important market share in China and even the world.However,there are still a number of problems in the process of development,and the policy support has a greater impact.In this paper,the development status of strategic emerging industries in Anhui Province was discussed firstly,and then the challenges and problems of the development was discussed.Finally,some science and technology promotion policies of strategic emerging industries in Anhui Province were proposed. 展开更多
关键词 Strategic emerging industries Market competitiveness Policy support
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Evolution of Handicraft Industries in the Textile Sector in Saudi Arabia: A Comprehensive Analysis of Trends and Innovations
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作者 Mona A. Alfawaz 《Journal of Textile Science and Technology》 2024年第3期82-100,共19页
This review explores the evolution of the textile handicraft industry in Saudi Arabia, emphasizing its cultural and economic significance. The study highlights the transition from traditional practices to modern innov... This review explores the evolution of the textile handicraft industry in Saudi Arabia, emphasizing its cultural and economic significance. The study highlights the transition from traditional practices to modern innovations and examines the impact of globalization and technological advancements on the industry. Key innovations are discussed, demonstrating their role in enhancing textile production while preserving cultural heritage. Major challenges, such as competition from industrial textiles and the need for sustainable practices, are identified. Opportunities for growth are explored, including leveraging tourism and international markets to promote Saudi handicrafts. The social and cultural impacts of the sector are underscored, particularly in sustaining community traditions and providing economic opportunities for artisans. Strategic recommendations for supporting and advancing the industry are offered, ensuring its continued relevance and sustainability in a rapidly changing global market. This analysis provides a robust framework for understanding the current state and future potential of Saudi Arabia’s textile handicraft industry. 展开更多
关键词 Handicraft industries Textile Sector Saudi Arabia Cultural Heritage Traditional Crafts Modern Technology Sustainability Global Market Innovation Artisanal Products
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Steps Toward Industry 5.0:Building“6S”Parallel Industries With Cyber-Physical-Social Intelligence 被引量:16
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作者 Xingxia Wang Jing Yang +7 位作者 Yutong Wang Qinghai Miao Fei-Yue Wang Aijun Zhao Jian-Ling Deng Lingxi Li Xiaoxiang Na Ljubo Vlacic 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第8期1692-1703,共12页
Very recently,intensive discussions and studies on Industry 5.0 have sprung up and caused the attention of researchers,entrepreneurs,and policymakers from various sectors around the world.However,there is no consensus... Very recently,intensive discussions and studies on Industry 5.0 have sprung up and caused the attention of researchers,entrepreneurs,and policymakers from various sectors around the world.However,there is no consensus on why and what is Industry 5.0 yet.In this paper,we define Industry 5.0from its philosophical and historical origin and evolution,emphasize its new thinking on virtual-real duality and human-machine interaction,and introduce its new theory and technology based on parallel intelligence(PI),artificial societies,computational experiments,and parallel execution(the ACP method),and cyber-physical-social systems(CPSS).Case studies and applications of Industry 5.0 over the last decade have been briefly summarized and analyzed with suggestions for its future development.We believe that Industry 5.0 of virtual-real interactive parallel industries has great potentials and is critical for building smart societies.Steps are outlined to ensure a roadmap that would lead to a smooth transition from CPS-based Industry 4.0 to CPSS-based Industry 5.0 for a better world which is Safe in physical spaces,S ecure in cyberspaces,Sustainable in ecology,Sensitive in individual privacy and rights,Service for all,and Smartness of all. 展开更多
关键词 ACP artificial intelligence CPS CPSS Industry 4.0 Industry 5.0 parallel industries parallel intelligence
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Comparison of biological behavior of lacrimal gland adenoid cystic carcinoma with high-grade transformation cells 被引量:2
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作者 Chuan-Li Zhang Li-Min Zhu +3 位作者 Xun Liu Mei-Xia Jiang Ting-Ting Lin Yan-Jin He 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第2期163-171,共9页
AIM:To evaluate the differences between human lacrimal gland adenoid cystic carcinoma with high-grade transformation(LACC-HGT)primar y cells cultured by high-grade transformation tissue and non-high-grade transformati... AIM:To evaluate the differences between human lacrimal gland adenoid cystic carcinoma with high-grade transformation(LACC-HGT)primar y cells cultured by high-grade transformation tissue and non-high-grade transformation(non-HGT)primary cells cultured by non-highgrade transformation tissue in proliferation,metastasis,drug susceptibility,and genes.METHODS:LACC-HGT primary cells were established by tissue block culture,and the 4^(th)to 10^(th)generation primary cells were selected as research objects.The cells were preliminarily identified by immunofluorescent staining.The differences between non-HGT and LACC-HGT primary cells in terms of proliferation,metastasis,and drug susceptibility were compared by cell counting kit-8(CCK-8)assay,wound healing,and drug sensitivity experiments.Differentially expressed genes were screened using mRNA array.Gene expression was analyzed using real-time quantitative polymerase chain reaction(RT-qPCR).RESULTS:LACC-HGT primary cells were successfully cultured by tissue block culture.Immunofluorescence staining results showed that cytokeratin(CK)and CK7 expression levels were positive in LACC-HGT primary cells.CCK-8 results showed that the proliferation ability of LACCHGT cells was significantly higher than that of non-HGT cells.Wound healing experiment showed that the migration ability of LACC-HGT cells was significantly higher than that of non-HGT cells.LACC-HGT cells were also less sensitive to cisplatin and paclitaxel than non-HGT cells.Compared with non-HGT cells,9566 differentially expressed genes were found in LACC-HGT primary cells,of which 5162 were upregulated and 4404 were down-regulated.The expression of N-acetylneuraminate pyruvate lyase(NPL),MARVEL domain containing 3(MARVELD3),syntabulin(SYBU),and allograft inflammatory factor 1(AIF1)was higher in LACCHGT cells than in non-HGT cells,whereas that of periostin(POSTN)was lower.CONCLUSION:LACC-HGT primary cells have faster proliferation,stronger migration ability,and poorer sensitivity to chemotherapy drugs than non-HGT primary cells.The expression of mRNAs in non-HGT and LACC-HGT primary cells are significantly different.These features are speculated to be the reasons why high-grade transformation tissues exhibit higher malignant degree and poorer prognosis than their counterparts. 展开更多
关键词 lacrimal gland lacrimal gland adenoid cystic carcinoma high-grade transformation primary cell culture biological behavior mRNA array
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Leveraging Blockchain with Optimal Deep Learning-Based Drug Supply Chain Management for Pharmaceutical Industries 被引量:1
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作者 Shanthi Perumalsamy Venkatesh Kaliyamurthy 《Computers, Materials & Continua》 SCIE EI 2023年第11期2341-2357,共17页
Due to its complexity and involvement of numerous stakeholders,the pharmaceutical supply chain presents many challenges that companies must overcome to deliver necessary medications to patients efficiently.The pharmac... Due to its complexity and involvement of numerous stakeholders,the pharmaceutical supply chain presents many challenges that companies must overcome to deliver necessary medications to patients efficiently.The pharmaceutical supply chain poses different challenging issues,encompasses supply chain visibility,cold-chain shipping,drug counterfeiting,and rising prescription drug prices,which can considerably surge out-of-pocket patient costs.Blockchain(BC)offers the technical base for such a scheme,as it could track legitimate drugs and avoid fake circulation.The designers presented the procedure of BC with fabric for creating a secured drug supplychain management(DSCM)method.With this motivation,the study presents a new blockchain with optimal deep learning-enabled DSCM and recommendation scheme(BCODL-DSCMRS)for Pharmaceutical Industries.Firstly,Hyperledger fabric is used for DSC management,enabling effective tracking processes in the smart pharmaceutical industry.In addition,a hybrid deep belief network(HDBN)model is used to suggest the best or top-rated medicines to healthcare providers and consumers.The spotted hyena optimizer(SHO)algorithm is used to optimize the performance of the HDBN model.The design of the HSO algorithm for tuning the HDBN model demonstrates the novelty of the work.The presented model is tested on the UCI repository’s open-access drug reviews database. 展开更多
关键词 Drug supply chain pharmaceutical industry deep learning blockchain hyper ledger fabric SECURITY drug recommendation
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Application of convolutional neural network-based endoscopic imaging in esophageal cancer or high-grade dysplasia: A systematic review and meta-analysis
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作者 Jun-Qi Zhang Jun-Jie Mi Rong Wang 《World Journal of Gastrointestinal Oncology》 SCIE 2023年第11期1998-2016,共19页
BACKGROUND Esophageal cancer is the seventh-most common cancer type worldwide,accounting for 5%of death from malignancy.Development of novel diagnostic techniques has facilitated screening,early detection,and improved... BACKGROUND Esophageal cancer is the seventh-most common cancer type worldwide,accounting for 5%of death from malignancy.Development of novel diagnostic techniques has facilitated screening,early detection,and improved prognosis.Convolutional neural network(CNN)-based image analysis promises great potential for diagnosing and determining the prognosis of esophageal cancer,enabling even early detection of dysplasia.METHODS PubMed,EMBASE,Web of Science and Cochrane Library databases were searched for articles published up to November 30,2022.We evaluated the diagnostic accuracy of using the CNN model with still image-based analysis and with video-based analysis for esophageal cancer or HGD,as well as for the invasion depth of esophageal cancer.The pooled sensitivity,pooled specificity,positive likelihood ratio(PLR),negative likelihood ratio(NLR),diagnostic odds ratio(DOR)and area under the curve(AUC)were estimated,together with the 95%confidence intervals(CI).A bivariate method and hierarchical summary receiver operating characteristic method were used to calculate the diagnostic test accuracy of the CNN model.Meta-regression and subgroup analyses were used to identify sources of hetero-geneity.RESULTS A total of 28 studies were included in this systematic review and meta-analysis.Using still image-based analysis for the diagnosis of esophageal cancer or HGD provided a pooled sensitivity of 0.95(95%CI:0.92-0.97),pooled specificity of 0.92(0.89-0.94),PLR of 11.5(8.3-16.0),NLR of 0.06(0.04-0.09),DOR of 205(115-365),and AUC of 0.98(0.96-0.99).When video-based analysis was used,a pooled sensitivity of 0.85(0.77-0.91),pooled specificity of 0.73(0.59-0.83),PLR of 3.1(1.9-5.0),NLR of 0.20(0.12-0.34),DOR of 15(6-38)and AUC of 0.87(0.84-0.90)were found.Prediction of invasion depth resulted in a pooled sensitivity of 0.90(0.87-0.92),pooled specificity of 0.83(95%CI:0.76-0.88),PLR of 7.8(1.9-32.0),NLR of 0.10(0.41-0.25),DOR of 118(11-1305),and AUC of 0.95(0.92-0.96).CONCLUSION CNN-based image analysis in diagnosing esophageal cancer and HGD is an excellent diagnostic method with high sensitivity and specificity that merits further investigation in large,multicenter clinical trials. 展开更多
关键词 Esophageal cancer high-grade dysplasia Convolutional neural network Deep learning Systematic review META-ANALYSIS
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Analysis on Technical Structure and Competitiveness of ICT Manufacturing Industries
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作者 Xiaojie Tu Zhuofang Li +1 位作者 Minlin Wu Rongyi Yan 《China Communications》 SCIE CSCD 2023年第3期361-374,共14页
In order to analyze the technical structure and international comparative advantage of the information and communication technology(ICT)manufacturing industry,a complete set of ICT manufacturing product categories has... In order to analyze the technical structure and international comparative advantage of the information and communication technology(ICT)manufacturing industry,a complete set of ICT manufacturing product categories has been constructed by matching National Economical Industry Classification(GB/T4754-2017)with Harmonized System(HS)Codes,based on the relevant definitions in International Standard Industrial Classification(ISIC).The proposed definition overcomes inherent defects such as inaccurate scopes,lagging data and rough categories,which are characterized by commonly utilized product-level based classification approaches.Within the given framework,this paper has designed the technology content related indicators from the perspective of production distribution,and divided ICT product categories into high-end,medium-end and lowend manufacturing classifications according to respective global shares.Then,we have calculated international market shares(IMS),revealed comparative advantages(RCA),and market penetration rates(MPR)of ICT manufacturing exports for major economies from 2010 to 2021.Finally,development characterizations of ICT manufacturing industries for China’s Mainland are analyzed,and several practical suggestions are provided. 展开更多
关键词 ICT manufacturing industry TECHNICAL
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Government Role in Fostering Emerging Technological Industries:A New Perspective for Industrial Policy Research
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作者 He Jun 《China Economist》 2023年第5期14-33,共20页
Mainstream industrial policy research cannot fully explain how government interventions have helped China’s mobile communications industry catch up with and overtake those of advanced nations.China’s mobile communic... Mainstream industrial policy research cannot fully explain how government interventions have helped China’s mobile communications industry catch up with and overtake those of advanced nations.China’s mobile communications industry made breakthroughs in 3G,caught up with advanced nations in 4G,and gained a leadership position in 5G due to the implementation and improvement of a strategy of industrial competition that accommodates mainstream standards and prioritizes the mid-band spectrum based on the integrated“technology,standard and industry”deployment system and swift decision-making.The introduction of a perspective of a strategy of industrial competition may supplement industrial policy research in the following ways:First,when the concerted actions of numerous innovators are important for industrial competition performance,an effective strategy of industrial competition can be devised and overall coordinated by the government provided that is compatible with the catch-up development of emerging technological industries.Second,an industrial policy becomes effective when it is complementary with the strategic factors for long-term industrial performance such as the strategy of industrial competition and avoids serious disruptions to market-based mechanisms. 展开更多
关键词 Government intervention strategy of industrial competition overall coordination swift decision-making
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Arithmetic Optimization with Deep Learning Enabled Churn Prediction Model for Telecommunication Industries
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作者 Vani Haridasan Kavitha Muthukumaran K.Hariharanath 《Intelligent Automation & Soft Computing》 SCIE 2023年第3期3531-3544,共14页
Customer retention is one of the challenging issues in different business sectors,and variousfirms utilize customer churn prediction(CCP)process to retain existing customers.Because of the direct impact on the company ... Customer retention is one of the challenging issues in different business sectors,and variousfirms utilize customer churn prediction(CCP)process to retain existing customers.Because of the direct impact on the company revenues,particularly in the telecommunication sector,firms are needed to design effective CCP models.The recent advances in machine learning(ML)and deep learning(DL)models enable researchers to introduce accurate CCP models in the telecom-munication sector.CCP can be considered as a classification problem,which aims to classify the customer into churners and non-churners.With this motivation,this article focuses on designing an arithmetic optimization algorithm(AOA)with stacked bidirectional long short-term memory(SBLSTM)model for CCP.The proposed AOA-SBLSTM model intends to proficiently forecast the occurrence of CC in the telecommunication industry.Initially,the AOA-SBLSTM model per-forms pre-processing to transform the original data into a useful format.Besides,the SBLSTM model is employed to categorize data into churners and non-chur-ners.To improve the CCP outcomes of the SBLSTM model,an optimal hyper-parameter tuning process using AOA is developed.A widespread simulation analysis of the AOA-SBLSTM model is tested using a benchmark dataset with 3333 samples and 21 features.The experimental outcomes reported the promising performance of the AOA-SBLSTM model over the recent approaches. 展开更多
关键词 Customer churn prediction business intelligence telecommunication industry decision making deep learning
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Carbon emission efficiency of forest processing industries in China
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作者 GUAN Zhi-jie Yahaya Idris MUSA +1 位作者 ZHANG Ya-xin GUO Zhi-yuan 《Ecological Economy》 2023年第3期217-232,共16页
This paper uses an input-output table of China's provinces(2007-2016) to measure carbon emissions of these industries.It employs a Malmquist-Luenberger(ML) index with expected and undesired outputs,and an absolute... This paper uses an input-output table of China's provinces(2007-2016) to measure carbon emissions of these industries.It employs a Malmquist-Luenberger(ML) index with expected and undesired outputs,and an absolute β convergence and a conditional β convergence model,to conduct an in-depth analysis of dynamic changes and spatial convergence.Carbon emission efficiency of forest processing industries in 25 regions,including Shanghai,Chongqing,Zhejiang,and Jiangsu are increasing,whereas those of Tianjin,Liaoning,Heilongjiang,and Tibet are decreasing.The main contributing factors of carbon emission efficiency in three major regions vary over time.Further,carbon emission efficiency in the eastern,central,and western regions all have absolute β convergence and conditional β convergence,indicating that different regions are developing toward their own goals and industry,yet regions with lower efficiency are catching up with those where with more efficient strategies in place.Finally,this paper proposes according recommendations. 展开更多
关键词 input-output model ML index CONVERGENCE carbon emission efficiency forest industry production
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Can Industrial Structure Upgrading Restrain Industrial Land Expansion?Evidence from China
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作者 CHEN Wei LI Qiao +1 位作者 ZHANG Sun ZHOU Xue 《Chinese Geographical Science》 SCIE CSCD 2024年第3期504-518,共15页
China has made great achievements in industrial development and is transforming into a powerful manufacturing country.Meanwhile,the industrial land scale is also expanding.However,whether industrial structure upgradin... China has made great achievements in industrial development and is transforming into a powerful manufacturing country.Meanwhile,the industrial land scale is also expanding.However,whether industrial structure upgrading achieves the purpose of restraining industrial land expansion remains unanswered.By calculating the industrial land structure index(ILSI)and industrial land expansion scale(ILES),this study analyzed their temporal and spatial distribution characteristics at both regional and city levels from 2007to 2020 in China.Results show that industrial land expansion presents a different trend in the four regions,the ILES in the eastern region is the largest,and the speed of industrial land expansion has declined since 2013,but it has gradually increased since 2016.The ILSI of the eastern and central regions is higher than that of the western and northeastern regions.Furthermore,a spatial Durbin model(SDM)has been established to estimate the spatial effect of industrial structure upgrading on industrial land expansion from 2007 to2020.Notably,industrial structure upgrading has not slowed industrial land expansion.The eastern and western regions require a greater amount of industrial land while upgrading the industrial structure.The improvement of the infrastructure level and international trade level has promoted industrial land expansion. 展开更多
关键词 industrial development industrial structure upgrading industrial land expansion regional differences China
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