This study focused on the mechanical behavior of a deep-buried tunnel constructed in horizontally layered limestone,and investigated the effect of a new combined rockboltecable support system on the tunnel response.Th...This study focused on the mechanical behavior of a deep-buried tunnel constructed in horizontally layered limestone,and investigated the effect of a new combined rockboltecable support system on the tunnel response.The Yujingshan Tunnel,excavated through a giant karst cave,was used as a case study.Firstly,a multi-objective optimization model for the rockboltecable support was proposed by using fuzzy mathematics and multi-objective comprehensive decision-making principles.Subsequently,the parameters of the surrounding rock were calibrated by comparing the simulation results obtained by the discrete element method(DEM)with the field monitoring data to obtain an optimized support scheme based on the optimization model.Finally,the optimization scheme was applied to the karst cave section,which was divided into the B-and C-shaped sections.The distribution range of the rockboltecable support in the C-shaped section was larger than that in the B-shaped section.The field monitoring results,including tunnel crown settlement,horizontal convergence,and axial force of the rockboltecable system,were analyzed to assess the effectiveness of the optimization scheme.The maximum crown settlement and horizontal convergence were measured to be 25.9 mm and 35 mm,accounting for 0.1%and 0.2%of the tunnel height and span,respectively.Although the C-shaped section had poorer rock properties than the B-shaped section,the crown settlement and horizontal convergence in the C-shaped section ranged from 46%to 97%of those observed in the B-shaped section.The cable axial force in the Bshaped section was approximately 60%of that in the C-shaped section.The axial force in the crown rockbolt was much smaller than that in the sidewall rockbolt.Field monitoring results demonstrated that the optimized scheme effectively controlled the deformation of the layered surrounding rock,ensuring that it remained within a safe range.These results provide valuable references for the design of support systems in deep-buried tunnels situated in layered rock masses.展开更多
The deformation control of surrounding rock in gobside roadway with thick and hard roof poses a significant challenge to the safety and efficiency of coal mining.To address this issue,a novel approach combining direct...The deformation control of surrounding rock in gobside roadway with thick and hard roof poses a significant challenge to the safety and efficiency of coal mining.To address this issue,a novel approach combining directional and non-directional blasting techniques,known as combined blasting,was proposed.This study focuses on the experimental investigation of the proposed method in the 122108 working face in Caojiatan Coal Mine as the engineering background.The initial phase of the study involves physical model experiments to reveal the underlying mechanisms of combined blasting for protecting gob-side roadway with thick and hard roof.The results demonstrate that this approach effectively accelerates the collapse of thick and hard roofs,enhances the fragmentation and expansion coefficient of gangue,facilitates the filling of the goaf with gangue,and provides support to the overlying strata,thus reducing the subsidence of the overlying strata above the goaf.Additionally,the method involves cutting the main roof into shorter beams to decrease the stress and disrupt stress transmission pathways.Subsequent numerical simulations were conducted to corroborate the findings of the physical model experiments,thus validating the accuracy of the experimental results.Furthermore,field engineering experiments were performed,affirming the efficacy of the combined blasting method in mitigating the deformation of surrounding rock and achieving the desired protection of the gob-side roadway.展开更多
Aiming at the characteristics of the poor steady ability, the short stable time and severe deformation behavior of weakly cemented soft surrounding rock around extraction roadway, a bolt–cable combined supporting tec...Aiming at the characteristics of the poor steady ability, the short stable time and severe deformation behavior of weakly cemented soft surrounding rock around extraction roadway, a bolt–cable combined supporting technology was proposed. Numerical simulation was performed by using FLAC3 D software to study the effects of different supporting systems. The simulation result proves that those supporting systems have good practical values. Based on real-time monitoring and analysis of the deformation of surrounding rock and the stress of supporting structure, real time information of deformation of surrounding rock and stress state of supporting structure of extraction roadway within weakly cemented strata was obtained. Monitoring results show that large deformation and failure of surrounding rock of extraction roadway within weakly cemented strata can be effectively controlled by the bolt–cable combined supporting technology, which ensures the long-term stability and safety of surrounding rock and supporting structure.展开更多
Power Quality (PQ) combined disturbances become common along with ubiquity of voltage flickers and harmonics. This paper presents a novel approach to classify the different patterns of PQ combined disturbances. The cl...Power Quality (PQ) combined disturbances become common along with ubiquity of voltage flickers and harmonics. This paper presents a novel approach to classify the different patterns of PQ combined disturbances. The classification system consists of two parts, namely the feature extraction and the automatic recognition. In the feature extraction stage, Phase Space Reconstruction (PSR), a time series analysis tool, is utilized to construct disturbance signal trajectories. For these trajectories, several indices are proposed to form the feature vectors. Support Vector Machines (SVMs) are then implemented to recognize the different patterns and to evaluate the efficiencies. The types of disturbances discussed include a combination of short-term dis-turbances (voltage sags, swells) and long-term disturbances (flickers, harmonics), as well as their homologous single ones. The feasibilities of the proposed approach are verified by simulation with thousands of PQ events. Comparison studies based on Wavelet Transform (WT) and Artificial Neural Network (ANN) are also reported to show its advantages.展开更多
Using the spatial structure of the external staggered split-level panel layout,a combined support technology for adjacent roadways was developed and analyzed for a rock bolt and anchor cable mechanism.The influence of...Using the spatial structure of the external staggered split-level panel layout,a combined support technology for adjacent roadways was developed and analyzed for a rock bolt and anchor cable mechanism.The influence of the side rock bolt and anchor cable parameters on the mechanical properties of the anchorage body and the support stress distribution of the lateral coal body were revealed using the FLAC3D software.The optimal support parameters of the side rock bolts and anchor cables were subsequently determined,and the support effect of gob-side entry in a mining scenario was verified.The results show that the support of the side rock bolts and anchor cables improves the mechanical properties and stress state of the anchorage body,producing a good protective effect on the coal body of the air-intake entry roof and side wall.This is beneficial to the stability of the side wall and the realization of the suspension effect for roof rock bolts and anchor cables,which in turn makes the surrounding rock maintenance of the gob-side entry to a thick coal seam more favorable.展开更多
In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses...In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high prestress.It is essential to study the support components performance under dynamic-static coupling conditions.Based on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so on.The bolt and cable mechanical tests are conducted by MAC system under different prestress levels.The results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly reduced.In the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress condition.In the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress condition.The MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system.展开更多
Our study group has developed a unique combined ters from the industries of dyestuff, pharmaceutical, chemical biological technology to treat high-strength organic wastewaengineering and zymolysis by using the princip...Our study group has developed a unique combined ters from the industries of dyestuff, pharmaceutical, chemical biological technology to treat high-strength organic wastewaengineering and zymolysis by using the principles of anaerobic ecological niche and bio-phase separation. The study obtained five national invention patents and eight patent equipments. This technology contains four kernel processes - two-phase anaerobic-aerobic process, hydrolysis-acidification-oxidation process, UASBAF-oxidation process, and internal cycling-hydrolysis-oxidation process. Fifteen pilot projects were accomplished in the basins of Tai Lake, Huai River, Liao River and Songhua River, and their total capital investment reached 185.214 million Yuan (RMB). Compared to conventional wastewater treatment technology, the innovative technology is more costeffective for high-strength organic wastewater treatment, can save capital investment by 15% - 30%, lessen land usage by 20% to 40% and decrease the operating cost by 10% to 25%. The operating cost of treatment per cubic meter industrial wastewater could be below 0.6 to 1.4 Yuan (RMB).展开更多
In this paper, a new spatial coherence model of seismic ground motions is proposed by a fitting procedure. The analytical expressions of modal combination (correlation) coefficients of structural response are develo...In this paper, a new spatial coherence model of seismic ground motions is proposed by a fitting procedure. The analytical expressions of modal combination (correlation) coefficients of structural response are developed for multi-support seismic excitations. The coefficients from both the numerical integration and analytical solutions are compared to verify the accuracy of the solutions. It is shown that the analytical expressions of numerical modal combination coefficients are of high accuracy. The results of random responses of an example bridge show that the analytical modal combination coefficients developed in this paper are accurate enough to meet the requirements needed in practice. In addition, the computational efficiency of the analytical solutions of the modal combination coefficients is demonstrated by the response computation of the example bridge. It is found that the time required for the structural response analysis by using the analytical modal combination coefficients is less than 1/20 of that using numerical integral methods.展开更多
Accurate fault prediction can obviously reduce cost and decrease the probability of accidents so as to improve the performance of the system testing and maintenance. Traditional fault prediction methods are always off...Accurate fault prediction can obviously reduce cost and decrease the probability of accidents so as to improve the performance of the system testing and maintenance. Traditional fault prediction methods are always offline that are not suitable for online and real-time processing. For the complicated nonlinear and non-stationary time series, it is hard to achieve exact predicting result with single models such as support vector regression (SVR), artifieial neural network (ANN), and autoregressive moving average (ARMA). Combined with the accurate online support vector regression (AOSVR) algorithm and ARMA model, a new online approach is presented to forecast fault with time series prediction. The fault trend feature can be extracted by the AOSVR with global kernel for general fault modes. Moreover, its prediction residual that represents the local high-frequency components is synchronously revised and compensated by the sliding time window ARMA model. Fault prediction with combined AOSVR and ARMA can be realized better than with the single one. Experiments on Tennessee Eastman process fault data show the new method is practical and effective.展开更多
Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons. Recombinant decorin suppresses inflammatory reactions, inhibit...Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons. Recombinant decorin suppresses inflammatory reactions, inhibits glial scar formation, and promotes axonal growth. Rat models of T8 spinal cord contusion were created with the NYU impactor and these models were subjected to combined transplantation of bone morphogenetic protein-4-induced glial-restricted precursor-derived astro- cytes and human recombinant decorin transplantation. At 28 days after spinal cord contusion, dou- ble-immunofluorescent histochemistry revealed that combined transplantation inhibited the early in- flammatory response in injured rats. Furthermore, brain-derived neurotrophic factor, which was se- creted by transplanted cells, protected injured axons. The combined transplantation promoted ax- onal regeneration and growth of injured motor and sensory neurons by inhibiting astrocyte prolif- eration and glial scar formation, with astrocytes forming a linear arrangement in the contused spinal cord, thus providing axonal regeneration channels.展开更多
One hundred patients with focal epilepsy were recruited for the present study and their seizures controlled with antiepileptic drugs. The patients then orally received a capsule of tall gastrodis tuber powder, a tradi...One hundred patients with focal epilepsy were recruited for the present study and their seizures controlled with antiepileptic drugs. The patients then orally received a capsule of tall gastrodis tuber powder, a traditional Chinese drug, and underwent single photon emission computed tomography, long-term electroencephalogram, and CT/MRI. Blood drug levels were monitored throughout the study. Before treatment with tall gastrodis tuber, 35 of the 100 cases had abnormal CT/MRI scans; 79 cases had abnormal single photon emission computed tomography images; 86 cases had abnormal electroencephalogram; and a total of 146 abnormal perfusion foci were observed across the 100 subjects. After treatment, the number of patients with normal single photon emission computed tomography images increased by 12; normal electroencephalogram was observed in an additional 27 cases and the number of patients with epileptiform discharge decreased by 29 (34% of 86); the total number of abnormal perfusion foci decreased by 52 (36%) and changes in abnormal loci were visible in 65 patients. These changes indicate that the administration of tall gastrodis tuber in combination with antiepileptic drugs repairs abnormal perfusion foci in patients with focal epilepsy Our results demonstrate that traditional Chinese drugs can repair abnormal perfusion foci and, as such, are a promising new pathway in the treatment of focal epilepsy.展开更多
基金supported by the Fundamental Research Funds for the Central Universities (Grant No.2023JBZY024)Beijing Natural Science Foundation (Grant No.9244040)opening Fund of State Key Laboratory of Geohazard Prevention and Geoenvironment Protection,Chengdu University of Technology (Grant No.SKLGP2023K015).
文摘This study focused on the mechanical behavior of a deep-buried tunnel constructed in horizontally layered limestone,and investigated the effect of a new combined rockboltecable support system on the tunnel response.The Yujingshan Tunnel,excavated through a giant karst cave,was used as a case study.Firstly,a multi-objective optimization model for the rockboltecable support was proposed by using fuzzy mathematics and multi-objective comprehensive decision-making principles.Subsequently,the parameters of the surrounding rock were calibrated by comparing the simulation results obtained by the discrete element method(DEM)with the field monitoring data to obtain an optimized support scheme based on the optimization model.Finally,the optimization scheme was applied to the karst cave section,which was divided into the B-and C-shaped sections.The distribution range of the rockboltecable support in the C-shaped section was larger than that in the B-shaped section.The field monitoring results,including tunnel crown settlement,horizontal convergence,and axial force of the rockboltecable system,were analyzed to assess the effectiveness of the optimization scheme.The maximum crown settlement and horizontal convergence were measured to be 25.9 mm and 35 mm,accounting for 0.1%and 0.2%of the tunnel height and span,respectively.Although the C-shaped section had poorer rock properties than the B-shaped section,the crown settlement and horizontal convergence in the C-shaped section ranged from 46%to 97%of those observed in the B-shaped section.The cable axial force in the Bshaped section was approximately 60%of that in the C-shaped section.The axial force in the crown rockbolt was much smaller than that in the sidewall rockbolt.Field monitoring results demonstrated that the optimized scheme effectively controlled the deformation of the layered surrounding rock,ensuring that it remained within a safe range.These results provide valuable references for the design of support systems in deep-buried tunnels situated in layered rock masses.
基金funding support from the National Natural Science Foundation of China(Grant Nos.52074298 and 52204164)Fundamental Research Funds for the Central Universities(Grant No.2022XJSB03).
文摘The deformation control of surrounding rock in gobside roadway with thick and hard roof poses a significant challenge to the safety and efficiency of coal mining.To address this issue,a novel approach combining directional and non-directional blasting techniques,known as combined blasting,was proposed.This study focuses on the experimental investigation of the proposed method in the 122108 working face in Caojiatan Coal Mine as the engineering background.The initial phase of the study involves physical model experiments to reveal the underlying mechanisms of combined blasting for protecting gob-side roadway with thick and hard roof.The results demonstrate that this approach effectively accelerates the collapse of thick and hard roofs,enhances the fragmentation and expansion coefficient of gangue,facilitates the filling of the goaf with gangue,and provides support to the overlying strata,thus reducing the subsidence of the overlying strata above the goaf.Additionally,the method involves cutting the main roof into shorter beams to decrease the stress and disrupt stress transmission pathways.Subsequent numerical simulations were conducted to corroborate the findings of the physical model experiments,thus validating the accuracy of the experimental results.Furthermore,field engineering experiments were performed,affirming the efficacy of the combined blasting method in mitigating the deformation of surrounding rock and achieving the desired protection of the gob-side roadway.
基金financially supported by the National Natural Science Foundation of China (Nos. 51174196, 51204168, 51109209 and 51309222)the Youth Fund Project of Jiangsu Province Natural Science Foundation (No. BK20130193)
文摘Aiming at the characteristics of the poor steady ability, the short stable time and severe deformation behavior of weakly cemented soft surrounding rock around extraction roadway, a bolt–cable combined supporting technology was proposed. Numerical simulation was performed by using FLAC3 D software to study the effects of different supporting systems. The simulation result proves that those supporting systems have good practical values. Based on real-time monitoring and analysis of the deformation of surrounding rock and the stress of supporting structure, real time information of deformation of surrounding rock and stress state of supporting structure of extraction roadway within weakly cemented strata was obtained. Monitoring results show that large deformation and failure of surrounding rock of extraction roadway within weakly cemented strata can be effectively controlled by the bolt–cable combined supporting technology, which ensures the long-term stability and safety of surrounding rock and supporting structure.
基金Project (No. 50437010) supported by the Key Program of the Na-tional Natural Science Foundation of China
文摘Power Quality (PQ) combined disturbances become common along with ubiquity of voltage flickers and harmonics. This paper presents a novel approach to classify the different patterns of PQ combined disturbances. The classification system consists of two parts, namely the feature extraction and the automatic recognition. In the feature extraction stage, Phase Space Reconstruction (PSR), a time series analysis tool, is utilized to construct disturbance signal trajectories. For these trajectories, several indices are proposed to form the feature vectors. Support Vector Machines (SVMs) are then implemented to recognize the different patterns and to evaluate the efficiencies. The types of disturbances discussed include a combination of short-term dis-turbances (voltage sags, swells) and long-term disturbances (flickers, harmonics), as well as their homologous single ones. The feasibilities of the proposed approach are verified by simulation with thousands of PQ events. Comparison studies based on Wavelet Transform (WT) and Artificial Neural Network (ANN) are also reported to show its advantages.
基金National Natural Science Foundation of Surface Project of China(Grant Nos.5177428952074291)+2 种基金The National Natural Science Foundation of the Youth Science Foundation of China(Grant No.51404270)The Fundamental Research Funds for the Central Universities(Grant No.2011QZ06)The Open Fund of State Key Laboratory of Coal Resources in Western China(Grant No.SKLCRKF1903).
文摘Using the spatial structure of the external staggered split-level panel layout,a combined support technology for adjacent roadways was developed and analyzed for a rock bolt and anchor cable mechanism.The influence of the side rock bolt and anchor cable parameters on the mechanical properties of the anchorage body and the support stress distribution of the lateral coal body were revealed using the FLAC3D software.The optimal support parameters of the side rock bolts and anchor cables were subsequently determined,and the support effect of gob-side entry in a mining scenario was verified.The results show that the support of the side rock bolts and anchor cables improves the mechanical properties and stress state of the anchorage body,producing a good protective effect on the coal body of the air-intake entry roof and side wall.This is beneficial to the stability of the side wall and the realization of the suspension effect for roof rock bolts and anchor cables,which in turn makes the surrounding rock maintenance of the gob-side entry to a thick coal seam more favorable.
基金supported by the National Natural Science Foundation of China(Nos.51927807,52074164,42277174,42077267 and 42177130)the Natural Science Foundation of Shandong Province,China(No.ZR2020JQ23)China University of Mining and Technology(Beijing)Top Innovative Talent Cultivation Fund for Doctoral Students(No.BBJ2023048)。
文摘In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high prestress.It is essential to study the support components performance under dynamic-static coupling conditions.Based on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so on.The bolt and cable mechanical tests are conducted by MAC system under different prestress levels.The results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly reduced.In the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress condition.In the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress condition.The MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system.
文摘Our study group has developed a unique combined ters from the industries of dyestuff, pharmaceutical, chemical biological technology to treat high-strength organic wastewaengineering and zymolysis by using the principles of anaerobic ecological niche and bio-phase separation. The study obtained five national invention patents and eight patent equipments. This technology contains four kernel processes - two-phase anaerobic-aerobic process, hydrolysis-acidification-oxidation process, UASBAF-oxidation process, and internal cycling-hydrolysis-oxidation process. Fifteen pilot projects were accomplished in the basins of Tai Lake, Huai River, Liao River and Songhua River, and their total capital investment reached 185.214 million Yuan (RMB). Compared to conventional wastewater treatment technology, the innovative technology is more costeffective for high-strength organic wastewater treatment, can save capital investment by 15% - 30%, lessen land usage by 20% to 40% and decrease the operating cost by 10% to 25%. The operating cost of treatment per cubic meter industrial wastewater could be below 0.6 to 1.4 Yuan (RMB).
基金National Natural Science Foundation of China Under Grant No. 50478112
文摘In this paper, a new spatial coherence model of seismic ground motions is proposed by a fitting procedure. The analytical expressions of modal combination (correlation) coefficients of structural response are developed for multi-support seismic excitations. The coefficients from both the numerical integration and analytical solutions are compared to verify the accuracy of the solutions. It is shown that the analytical expressions of numerical modal combination coefficients are of high accuracy. The results of random responses of an example bridge show that the analytical modal combination coefficients developed in this paper are accurate enough to meet the requirements needed in practice. In addition, the computational efficiency of the analytical solutions of the modal combination coefficients is demonstrated by the response computation of the example bridge. It is found that the time required for the structural response analysis by using the analytical modal combination coefficients is less than 1/20 of that using numerical integral methods.
文摘Accurate fault prediction can obviously reduce cost and decrease the probability of accidents so as to improve the performance of the system testing and maintenance. Traditional fault prediction methods are always offline that are not suitable for online and real-time processing. For the complicated nonlinear and non-stationary time series, it is hard to achieve exact predicting result with single models such as support vector regression (SVR), artifieial neural network (ANN), and autoregressive moving average (ARMA). Combined with the accurate online support vector regression (AOSVR) algorithm and ARMA model, a new online approach is presented to forecast fault with time series prediction. The fault trend feature can be extracted by the AOSVR with global kernel for general fault modes. Moreover, its prediction residual that represents the local high-frequency components is synchronously revised and compensated by the sliding time window ARMA model. Fault prediction with combined AOSVR and ARMA can be realized better than with the single one. Experiments on Tennessee Eastman process fault data show the new method is practical and effective.
基金supported by funding from the Ministry of Finance People’s Republic of ChinaChina Rehabilitation Research Center Research Program grants, No. 2008-2,2008-3, 2008-4, 2008-5
文摘Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons. Recombinant decorin suppresses inflammatory reactions, inhibits glial scar formation, and promotes axonal growth. Rat models of T8 spinal cord contusion were created with the NYU impactor and these models were subjected to combined transplantation of bone morphogenetic protein-4-induced glial-restricted precursor-derived astro- cytes and human recombinant decorin transplantation. At 28 days after spinal cord contusion, dou- ble-immunofluorescent histochemistry revealed that combined transplantation inhibited the early in- flammatory response in injured rats. Furthermore, brain-derived neurotrophic factor, which was se- creted by transplanted cells, protected injured axons. The combined transplantation promoted ax- onal regeneration and growth of injured motor and sensory neurons by inhibiting astrocyte prolif- eration and glial scar formation, with astrocytes forming a linear arrangement in the contused spinal cord, thus providing axonal regeneration channels.
基金funded by the Key Project of Gansu Province, No.2GS054-A43-014-19
文摘One hundred patients with focal epilepsy were recruited for the present study and their seizures controlled with antiepileptic drugs. The patients then orally received a capsule of tall gastrodis tuber powder, a traditional Chinese drug, and underwent single photon emission computed tomography, long-term electroencephalogram, and CT/MRI. Blood drug levels were monitored throughout the study. Before treatment with tall gastrodis tuber, 35 of the 100 cases had abnormal CT/MRI scans; 79 cases had abnormal single photon emission computed tomography images; 86 cases had abnormal electroencephalogram; and a total of 146 abnormal perfusion foci were observed across the 100 subjects. After treatment, the number of patients with normal single photon emission computed tomography images increased by 12; normal electroencephalogram was observed in an additional 27 cases and the number of patients with epileptiform discharge decreased by 29 (34% of 86); the total number of abnormal perfusion foci decreased by 52 (36%) and changes in abnormal loci were visible in 65 patients. These changes indicate that the administration of tall gastrodis tuber in combination with antiepileptic drugs repairs abnormal perfusion foci in patients with focal epilepsy Our results demonstrate that traditional Chinese drugs can repair abnormal perfusion foci and, as such, are a promising new pathway in the treatment of focal epilepsy.