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China's Imp.& Exp.of New and High-tech Products
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《中国经贸》 2002年第10期22-23,共2页
Import of New and High-tech Products Increases Rapidly The proportion of new and high-tech products in the total import continues to increase.Ever since 1991,the proportion of new and high-tech products in the total i... Import of New and High-tech Products Increases Rapidly The proportion of new and high-tech products in the total import continues to increase.Ever since 1991,the proportion of new and high-tech products in the total import has experienced a continuous growth.It took up only 14.8% of the total import in 1991.The figure reached 20.8% in 1998,and further rose to that of 26.3% in 2001.From January to June this year,the import of new and hightech products totaled 34.540 billion USD,up 18.1% over the same per... 展开更多
关键词 PR HIGH Exp.of New and high-tech products China’s Imp
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National Concentration of High-tech Products:The Second Great Diverqence?
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作者 Bing Lu Jiandong Ju Xinding Yu 《China & World Economy》 2023年第1期88-118,共31页
Based on the product-country level trade data from 2004 to 2017,as well as the High-Tech Products Catalog from the US Census Bureau,this paper examines empirically the current phenomenon of"national concentration... Based on the product-country level trade data from 2004 to 2017,as well as the High-Tech Products Catalog from the US Census Bureau,this paper examines empirically the current phenomenon of"national concentration"in high-tech exports.The results show that the phenomenon of"national concentration"not only exists but also tends to be self-reinforcing.Compared with other products,the exports of high-tech products tend to be concentrated in certain countries,and this concentration trends were further strengthened after the global financial crisis of2008-2009.The national concentration of R&D activities may be one of the important causes of the national concentration of high-tech products.This pattern remains robust when we further use the value-added export data and different definitions of high-tech products.We argue that the phenomenon of"national concentration"of high-tech exports may herald the arrival of the"Second Great Divergence"-the divergence between innovative and manufacturing activities-in the global economy. 展开更多
关键词 high-tech products national concentration R&D second great divergence
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Research on Risk Identification and Industrial Governance of Digital Education Products Based on Data Annotation Technology
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作者 Tong Lili Zeng Jia +1 位作者 Di Ying Wang Nan 《China Communications》 SCIE CSCD 2024年第3期273-282,共10页
The social transformation brought aboutby digital technology is deeply impacting various industries.Digital education products, with core technologiessuch as 5G, AI, IoT (Internet of Things),etc., are continuously pen... The social transformation brought aboutby digital technology is deeply impacting various industries.Digital education products, with core technologiessuch as 5G, AI, IoT (Internet of Things),etc., are continuously penetrating areas such as teaching,management, and evaluation. Apps, miniprograms,and emerging large-scale models are providingexcellent knowledge performance and flexiblecross-media output. However, they also exposerisks such as content discrimination and algorithmcommercialization. This paper conducts anevidence-based analysis of digital education productrisks from four dimensions: “digital resourcesinformationdissemination-algorithm design-cognitiveassessment”. It breaks through corresponding identificationtechnologies and, relying on the diverse characteristicsof governance systems, explores governancestrategies for digital education products from the threedomains of “regulators-developers-users”. 展开更多
关键词 digital education products industry governance risk identification
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Upcycling plastic wastes into value-added products via electrocatalysis and photoelectrocatalysis
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作者 Sungsoon Kim Dongjae Kong +1 位作者 Xiaolin Zheng Jong Hyeok Park 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第4期522-541,共20页
Plastic,renowned for its versatility,durability,and cost-effectiveness,is indispensable in modern society.Nevertheless,the annual production of nearly 400 million tons of plastic,coupled with a recycling rate of only ... Plastic,renowned for its versatility,durability,and cost-effectiveness,is indispensable in modern society.Nevertheless,the annual production of nearly 400 million tons of plastic,coupled with a recycling rate of only 9%,has led to a monumental environmental crisis.Plastic recycling has emerged as a vital response to this crisis,offering sustainable solutions to mitigate its environmental impact.Among these recycling efforts,plastic upcycling has garnered attention,which elevates discarded plastics into higher-value products.Here,electrocatalytic and photoelectrocatalytic treatments stand at the forefront of advanced plastic upcycling.Electrocatalytic or photoelectrocatalytic treatments involve chemical reactions that facilitate electron transfer through the electrode/electrolyte interface,driven by electrical or solar energy,respectively.These methods enable precise control of chemical reactions,harnessing potential,current density,or light to yield valuable chemical products.This review explores recent progress in plastic upcycling through electrocatalytic and photoelectrocatalytic pathways,offering promising solutions to the plastic waste crisis and advancing sustainability in the plastics industry. 展开更多
关键词 Plastic upcycling Electrocatalytic reaction Photoelectrocatalytic reaction Value-added product
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Dilation,discrimination and Uhlmann's theorem of link products of quantum channels
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作者 雷强 操刘桁 +1 位作者 Asutosh Kumar 武俊德 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期201-206,共6页
We establish the Stinespring dilation theorem of the link product of quantum channels in two different ways,discuss the discrimination of quantum channels,and show that the distinguishability can be improved by self-l... We establish the Stinespring dilation theorem of the link product of quantum channels in two different ways,discuss the discrimination of quantum channels,and show that the distinguishability can be improved by self-linking each quantum channel n times as n grows.We also find that the maximum value of Uhlmann's theorem can be achieved for diagonal channels. 展开更多
关键词 quantum channels link products Stinespring dilation theorem Uhlmann's theorem
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Quantifying the agreement and accuracy characteristics of four satellite-based LULC products for cropland classification in China
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作者 Jie Xue Xianglin Zhang +3 位作者 Songchao Chen Bifeng Hu Nan Wang Zhou Shi 《Journal of Integrative Agriculture》 SCIE CSCD 2024年第1期283-297,共15页
Various land use and land cover(LULC)products have been produced over the past decade with the development of remote sensing technology.Despite the differences in LULC classification schemes,there is a lack of researc... Various land use and land cover(LULC)products have been produced over the past decade with the development of remote sensing technology.Despite the differences in LULC classification schemes,there is a lack of research on assessing the accuracy of their application to croplands in a unified framework.Thus,this study evaluated the spatial and area accuracies of cropland classification for four commonly used global LULC products(i.e.,MCD12Q1V6,GlobCover2009,FROM-GLC and GlobeLand30)based on the harmonised FAO criterion,and quantified the relationships between four factors(i.e.,slope,elevation,field size and crop system)and cropland classification agreement.The validation results indicated that MCD12Q1 and GlobeLand30 performed well in cropland classification regarding spatial consistency,with overall accuracies of 94.90 and 93.52%,respectively.The FROMGLC showed the worst performance,with an overall accuracy of 83.17%.Overlaying the cropland generated by the four global LULC products,we found the proportions of complete agreement and disagreement were 15.51 and 44.72% for the cropland classification,respectively.High consistency was mainly observed in the Northeast China Plain,the Huang-Huai-Hai Plain and the northern part of the Middle-lower Yangtze Plain,China.In contrast,low consistency was detected primarily on the eastern edge of the northern and semiarid region,the Yunnan-Guizhou Plateau and southern China.Field size was the most important factor for mapping cropland.For area accuracy,compared with China Statistical Yearbook data at the provincial scale,the accuracies of different products in descending order were:GlobeLand30,FROM-GLC,MCD12Q1,and GlobCover2009.The cropland classification schemes mainly caused large area deviations among the four products,and they also resulted in the different ranks of spatial accuracy and area accuracy among the four products.Our results can provide valuable suggestions for selecting cropland products at the national or provincial scale and help cropland mapping and reconstruction,which is essential for food security and crop management,so they can also contribute to achieving the Sustainable Development Goals issued by the United Nations. 展开更多
关键词 global LULC products cropland mapping accuracy evaluation food security China
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Mixed Integer Robust Programming Model for Multimodal Fresh Agricultural Products Terminal Distribution Network Design
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作者 Feng Yang Zhong Wu Xiaoyan Teng 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第1期719-738,共20页
The low efficiency and high cost of fresh agricultural product terminal distribution directly restrict the operation of the entire supply network.To reduce costs and optimize the distribution network,we construct a mi... The low efficiency and high cost of fresh agricultural product terminal distribution directly restrict the operation of the entire supply network.To reduce costs and optimize the distribution network,we construct a mixed integer programmingmodel that comprehensively considers tominimize fixed,transportation,fresh-keeping,time,carbon emissions,and performance incentive costs.We analyzed the performance of traditional rider distribution and robot distribution modes in detail.In addition,the uncertainty of the actual market demand poses a huge threat to the stability of the terminal distribution network.In order to resist uncertain interference,we further extend the model to a robust counterpart form.The results of the simulation show that the instability of random parameters will lead to an increase in the cost.Compared with the traditional rider distribution mode,the robot distribution mode can save 12.7%on logistics costs,and the distribution efficiency is higher.Our research can provide support for the design of planning schemes for transportation enterprise managers. 展开更多
关键词 Fresh agricultural product terminal distribution network rider delivery robot delivery UNCERTAINTY
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Targeting oxidative stress with natural products: A novel strategy for esophageal cancer therapy
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作者 Fang Cao Han-Ling Zhang +2 位作者 Cui Guo Xue-Liang Xu Qiang Yuan 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第2期287-299,共13页
Esophageal cancer(ESC)is a malignant tumor that originates from the mucosal epithelium of the esophagus and is part of the digestive tract.Although the exact pathogenesis of ESC has not been fully elucidated,excessive... Esophageal cancer(ESC)is a malignant tumor that originates from the mucosal epithelium of the esophagus and is part of the digestive tract.Although the exact pathogenesis of ESC has not been fully elucidated,excessive oxidative stress is an important characteristic that leads to the development of many cancers.Abnormal expression of several proteins and transcription factors contributes to oxidative stress in ESCs,which alters the growth and proliferation of ESCs and promotes their metastasis.Natural compounds,including alkaloids,terpenes,polyphenols,and xanthine compounds,can inhibit reactive oxygen species production in ESCs.These compounds reduce oxidative stress levels and subsequently inhibit the oc-currence and progression of ESC through the regulation of targets and pathways such as the cytokine interleukins 6 and 10,superoxide dismutase,the NF-+ACY-kappa+ADs-B/MAPK pathway,and the mammalian Nrf2/ARE target pathway.Thus,targeting tumor oxidative stress has become a key focus in anti-ESC therapy.This review discusses the potential of Natural products(NPs)for treating ESCs and summarizes the application prospects of oxidative stress as a new target for ESC treatment.The findings of this review provide a reference for drug development targeting ESCs.Nonetheless,further high-quality studies will be necessary to determine the clinical efficacy of these various NPs. 展开更多
关键词 Oxidative stress Natural products Esophageal cancer Reactive oxygen species
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Identification of Antioxidant Additives in Food Products Sold in Dakar Markets
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作者 Alé Kane Papa Amadou Diakhaté +3 位作者 Sokhna Ndao Modou Dieng Mady Cisse Amadou Diop 《Open Journal of Applied Sciences》 2024年第1期51-62,共12页
The use of food additives in industrial production has the advantage of improving sensory properties, technological quality and extending the shelf life of foods. Among the most widely used additives are antioxidants,... The use of food additives in industrial production has the advantage of improving sensory properties, technological quality and extending the shelf life of foods. Among the most widely used additives are antioxidants, which prevent oxidation, browning and rancidity reactions in foods. However, the strong presence of these additives on the market is not without risks for human health, and should be controlled to guarantee food safety. Analysis of the risks associated with consumption of foods containing these additives requires, among other things, information on the frequency of use of these additives in various consumer products. The aim of this study is therefore to identify the antioxidants present in industrial food products distributed in Dakar. The methodology adopted consists of a qualitative analysis based on the identification of additives from food labels. Investigations were carried out in 9 stores, 4 superettes and 2 supermarkets located in different districts of Dakar. The results revealed the presence of 12 antioxidant additives, dominated by citric acid (53%) and ascorbic acid (29%). These studies have also highlighted the simultaneous use of several antioxidants in the same food product. Moreover, for some artificial antioxidants identified antioxydant such as BHA and BHT, health risks are associated with their consumption. The results of this study open up prospects for the development of information databases on food additives. 展开更多
关键词 ADDITIVES ANTIOXIDANT Food products MARKET RISK
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Regulatory role of peroxynitrite in advanced glycation end products mediated diabetic cardiovascular complications
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作者 Asis Bala 《World Journal of Diabetes》 SCIE 2024年第3期572-574,共3页
The Advanced Glycation End Products(AGE)binding with its receptor can increase reactive oxygen species(ROS)generation through specific signaling mediators.The effect of superoxide(O2-)and O2-mediated ROS and reactive ... The Advanced Glycation End Products(AGE)binding with its receptor can increase reactive oxygen species(ROS)generation through specific signaling mediators.The effect of superoxide(O2-)and O2-mediated ROS and reactive nitrogen species depends on their concentration and location of formation.Nitric oxide(NO)has anti-inflammatory and anticoagulant properties and a vasodilation effect,but NO can be deactivated by reacting with O_(2)^(-).This reaction between NO and O2-produces the potent oxidant ONOO−.Therefore,ONOO-'s regulatory role in AGEs in diabetic cardiovascular complications must considered as a regulator of cardiovascular complications in diabetes. 展开更多
关键词 DIABETES Cardiovascular complication Advanced glycation end products Reactive oxygen species Reactive nitrogen species PEROXYNITRITE
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A ratiometric fluorescent probe for hypoxanthine detection in aquatic products based on the enzyme mimics and fluorescence of cobalt-doped carbon nitride
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作者 Xin Wang Chengyi Hong +1 位作者 Zhengzhong Lin Zhiyong Huang 《Food Science and Human Wellness》 SCIE CSCD 2024年第2期879-884,共6页
A ratiometric fluorescent probe for hypoxanthine(Hx)detection was established based on the mimic enzyme and fluorescence characteristics of cobalt-doped graphite-phase carbon nitride(Co doped g-C_(3)N_(4)).In addition... A ratiometric fluorescent probe for hypoxanthine(Hx)detection was established based on the mimic enzyme and fluorescence characteristics of cobalt-doped graphite-phase carbon nitride(Co doped g-C_(3)N_(4)).In addition to emitting strong fluorescence,the peroxidase activity of Co doped g-C_(3)N_(4)can catalyze the reaction of O-phenylenediamine and H_(2)O_(2)to produce diallyl phthalate which can emit yellow fluorescence at 570 nm.Through the decomposition of Hx by xanthine oxidase,Hx can be indirectly detected by the generating hydrogen peroxide based on the measurement of fluorescent ratio I(F_(570)/F_(370)).The linear range was 1.7-272.2 mg/kg(R^(2)=0.997),and the detection limit was 1.52 mg/kg(3σ/K,n=9).The established method was applied to Hx detection in bass,grass carp,and shrimp,and the data were verified by HPLC.The result shows that the established probe is sensitive,accurate,and reliable,and can be used for Hx detection in aquatic products. 展开更多
关键词 Co doped g-C_(3)N_(4) Ratiometric fluorescent probe HYPOXANTHINE FRESHNESS Aquatic products
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Analysis on the Development Model of Relic and Museum Tourism Products Based on ERP Analysis:A Case Study on Shandong Province
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作者 WANG Xia 《Journal of Landscape Research》 2024年第1期77-82,共6页
In recent years, the trend of people choosing relic and museum tourism during their vacationand leisure time is growing day by day, mainly because it touches people's feelings about historical relicsand cultural h... In recent years, the trend of people choosing relic and museum tourism during their vacationand leisure time is growing day by day, mainly because it touches people's feelings about historical relicsand cultural heritage. The development of relic and museum tourism products is not only the inheritanceof culture and the protection of cultural relics, but also the promotion of tourism consumption under thebackground of cultural tourism integration, which has promoted the development of regional economy.With the relic and museum tourism resources in Shandong Province as the research object, through theanalysis of its resources, market and products, this paper put forward three applicable modes of relic andmuseum tourism product development, including independent development, joint development, and artauthorization, and proposed specific suggestions around the three modes. 展开更多
关键词 ERP analysis Relic and museum tourism product development Shandong Province
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Molecular engineering binuclear copper catalysts for selective CO_(2) reduction to C_(2) products
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作者 Qi Zhao Kai Lei +2 位作者 Bao Yu Xia Rachel Crespo-Otero Devis Di Tommaso 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第6期166-173,I0005,共9页
Molecular copper catalysts serve as exemplary models for correlating the structure-reaction-mechanism relationship in the electrochemical CO_(2) reduction(eCO_(2)R),owing to their adaptable environments surrounding th... Molecular copper catalysts serve as exemplary models for correlating the structure-reaction-mechanism relationship in the electrochemical CO_(2) reduction(eCO_(2)R),owing to their adaptable environments surrounding the copper metal centres.This investigation,employing density functional theory calculations,focuses on a novel family of binuclear Cu molecular catalysts.The modulation of their coordination configuration through the introduction of organic groups aims to assess their efficacy in converting CO_(2) to C_(2)products.Our findings highlight the crucial role of chemical valence state in shaping the characteristics of binuclear Cu catalysts,consequently influencing the eCO_(2)R behaviour,Notably,the Cu(Ⅱ)Cu(Ⅱ)macrocycle catalyst exhibits enhanced suppression of the hydrogen evolution reaction(HER),facilitating proton trans fer and the eCO_(2)R process.Fu rthermore,we explo re the impact of diverse electro n-withdrawing and electron-donating groups coordinated to the macrocycle(R=-F,-H,and-OCH_3)on the electron distribution in the molecular catalysts.Strategic placement of-OCH_3 groups in the macrocycles leads to a favourable oxidation state of the Cu centres and subsequent C-C coupling to form C_(2) products.This research provides fundamental insights into the design and optimization of binuclear Cu molecular catalysts for the electrochemical conversion of CO_(2) to value-added C_(2) products. 展开更多
关键词 Molecular catalyst design Selective CO_(2)reduction C_(2)products Density functional theory calculations
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Procyanidin A_1 and its digestive products alleviate acrylamide-induced IPEC-J2 cell damage through regulating Keap1/Nrf2 pathway
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作者 Fangfang Yan Qun Lu +1 位作者 Chengming Wang Rui Liu 《Food Science and Human Wellness》 SCIE CSCD 2024年第3期1475-1484,共10页
Our previous study has revealed that procyanidin A_(1)(A_(1))and its simulated digestive product(D-A,)can alleviate acrylamide(ACR)-induced intestine cell damage.However,the underlying mechanism remains unknown.In thi... Our previous study has revealed that procyanidin A_(1)(A_(1))and its simulated digestive product(D-A,)can alleviate acrylamide(ACR)-induced intestine cell damage.However,the underlying mechanism remains unknown.In this study,we elucidated the molecular mechanism for and D-A_(1) to alleviate ACR-stimulated IPEC-J2 cell damage.ACR slightly activated nuclear factor erythroid 2-related factor 2(Nrf2)signaling and its target genes,but this activation could not reduce intestine cell damage.A_(1) and D-A_(1) could alleviate ACR-induced cell damage,but the effect was abrogated in cells transiently transfected with Nrf2 small interfering RNA(siRNA).Further investigation confirmed that A_(1) and D-A_(1) interacted with Ketch-like ECH-associated protein 1(Keapl),which boosted the stabilization of Nrf2,subsequently promoted the translocation of Nrf2 into the nucleus,and further increased the expression of antioxidant proteins,thereby inhibiting glutathione(GSH)consumption,maintaining redox balance and eventually alleviating ACR-induced cell damage.Importantly,there was no difference between A_(1) and D-A_(1) treated groups,indicating that A_(1) can tolerate gastrointestinal digestion and may be a potential compound to limit the toxicity of ACR. 展开更多
关键词 Procyanidin A_1 Digestive products Acrylamide Nuclear factor erythroid 2-related factor 2(Nrf2) Intestinal cell damage
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The Customer Requirements Analysis Method of Engineering Products Based on Multiple Preference Information
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作者 Guo Mao 《Proceedings of Business and Economic Studies》 2024年第1期204-209,共6页
To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred ... To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred information form to evaluate the importance of each customer requirement.Secondly,a transfer function is employed to unify various forms of preference information into a fuzzy complementary judgment matrix.The ranking vector is then calculated using row and normalization methods,and the initial importance of customer requirements is obtained by aggregating the weights of decision members.Finally,the correction coefficients of initial importance and each demand are synthesized,and the importance of customer requirements is determined through normalization.The development example of the PE jaw crusher demonstrates the effectiveness and feasibility of the proposed method. 展开更多
关键词 product planning Customer requirements Importance ratings Multi-format information
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Research on Narrative Design of Creative Products Based on Regional Cultural Elements
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作者 Qiqiong Huang Mohd Mustafa Mohd Ghazali 《Journal of Contemporary Educational Research》 2024年第1期65-73,共9页
The research explored the ways and means of narrative design in which regional cultural elements are integrated into cultural and creative products.It also researched a new way of thinking and methods of creative prod... The research explored the ways and means of narrative design in which regional cultural elements are integrated into cultural and creative products.It also researched a new way of thinking and methods of creative product design based on regional cultural elements in order to satisfy consumers’emotional and cultural experiences.Narrative theory takes the perspective of narrative expression in the design of cultural and creative products.The regional cultural elements were used for better interactive communication with consumers in the form of cultural and creative products.In the narrative of cultural and creative product design,intervening in the development of regional cultural and creative design from the perspective of narratology can better exert and create the cultural value of the region itself,with cultural and creative products playing an important role in“local cultural stories.”This research adopted a qualitative approach and provided ideas and guidance for the narrative design and expression of regional cultural elements in creative products through comparative analysis of case studies.The research highlighted the role of narrative design in creating multi-layered experiences,weaving regional cultural stories into products,and the importance of deep understanding and effective use of regional cultural elements in design. 展开更多
关键词 Regional cultural elements Creative products Narrative design
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Research of Blockchain Technology in the Traceability of Characteristic Agricultural Products
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作者 Qian Zhang 《Journal of Electronic Research and Application》 2024年第3期60-65,共6页
With the increasingly prominent problem of food safety,the quality traceability of characteristic agricultural products has become a pressing issue.This study focuses on the application of blockchain technology in the... With the increasingly prominent problem of food safety,the quality traceability of characteristic agricultural products has become a pressing issue.This study focuses on the application of blockchain technology in the traceability of characteristic agricultural products,aiming to explore its potential and practical value in improving the efficiency and transparency of the traceability system of agricultural products.Through the combination of case analysis and model construction,a blockchain-based traceability system for characteristic agricultural products was established.The results showed that the traceability system could effectively record the whole process information of agricultural products from production and processing to sales,and greatly improve the immutability and traceability of data.Lastly,this paper also points out that the use of blockchain technology can improve the market trust in characteristic agricultural products,provide consumers with authentic and reliable product information,and provide new technical means for the quality management of agricultural products. 展开更多
关键词 Blockchain technology Characteristic agricultural products Traceability system Data immutability Market trust
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Advanced glycation end products:Key mediator and therapeutic target of cardiovascular complications in diabetes 被引量:1
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作者 Savita Bansal Archana Burman Asok Kumar Tripathi 《World Journal of Diabetes》 SCIE 2023年第8期1146-1162,共17页
The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns.Cardiovascular complications associated with diabetes are the leading cause o... The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns.Cardiovascular complications associated with diabetes are the leading cause of morbidity and mortality.The cardiovascular diseases that accompany diabetes include angina,myocardial infarction,stroke,peripheral artery disease,and congestive heart failure.Among the various risk factors generated secondary to hyperglycemic situations,advanced glycation end products(AGEs)are one of the important targets for future diagnosis and prevention of diabetes.In the last decade,AGEs have drawn a lot of attention due to their involvement in diabetic pathophysiology.AGEs can be derived exogenously and endogenously through various pathways.These are a nonhomogeneous,chemically diverse group of compounds formed nonenzymatically by condensation between carbonyl groups of reducing sugars and free amino groups of protein,lipids,and nucleic acid.AGEs mediate their pathological effects at the cellular and extracellular levels by multiple pathways.At the cellular level,they activate signaling cascades via the receptor for AGEs and initiate a complex series of intracellular signaling resulting in reactive oxygen species generation,inflammation,cellular proliferation,and fibrosis that may possibly exacerbate the damaging effects on cardiac functions in diabetics.AGEs also cause covalent modifications and cross-linking of serum and extracellular matrix proteins;altering their structure,stability,and functions.Early diagnosis of diabetes may prevent its progression to complications and decrease its associated comorbidities.In the present review,we recapitulate the role of AGEs as a crucial mediator of hyperglycemia-mediated detrimental effects in diabetes-associated complications.Furthermore,this review presents an overview of future perspectives for new therapeutic interventions to ameliorate cardiovascular complications in diabetes. 展开更多
关键词 Type 2 diabetes mellitus Cardiovascular complications HYPERGLYCEMIA Advanced glycation end products Reactive oxygen species Oxidative stress Endothelial cells Receptor of advanced glycation end products Anti-advanced glycation end products strategies
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Research of detonation products of RDX/Al from the perspective of composition 被引量:1
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作者 Xing-han Li Zhi-cong Yi +6 位作者 Qi-jun Liu Fu-sheng Liu Ze-teng Zhang Shen-yuan Hou Xian-xu Zheng Xu Zhang Hong-bo Pei 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第6期31-45,共15页
Aluminized explosives exhibit excellent performance because the oxidation of aluminum(Al)powders enhances the pressure and temperature of detonation products.However,the equation of state(EOS)of detonation products ha... Aluminized explosives exhibit excellent performance because the oxidation of aluminum(Al)powders enhances the pressure and temperature of detonation products.However,the equation of state(EOS)of detonation products has not been understood well.In the present study,we conducted long-time tests(approximately 1 ms)of a metal rod driven by detonation products of RDX,RDX/Li F,and RDX/Al.In addition,we used laser velocimetry(PDV)to measure the freesurface velocity of the rod.Thermochemical code DLCHEQ was successfully applied to the hydrodynamic program SSS to perform the roddriven test,and a novel method was established to study the EOS of detonation products from the perspective of composition.The reliability of DLCEHQ was validated by a small deviation(<10%)between the experimental rod free-surface velocity of RDX and the calculated results;the deviation was considerably less than that from the results obtained using the JWL EOS and ideal-gas EOS.The endothermic process and the reaction of Al powders(Al+H_(2)O+NO+CO_(2)→CO+H_(2)+N_(2)+Al_(2)O_(3))were analyzed by calculating the rod free-surface velocity of RDX/Li F and RDX/Al,respectively.The results of the present study demonstrated that the thermodynamic state of Al powders has notable influence on the EOS of aluminized detonation products,and the findings were compared with those of previous studies.First,the temperature equilibrium between Al powders and CHNO products is not always achieved,and the disequilibrium is more obvious when the reaction of Al powders is stronger.Second,the reaction rate of Al powders depends on pressure and Al content.Finally,the endothermic process of Al powders has a high contribution to the decrease in the work ability of RDX/Al instead of the gasconsumption mechanism of the Al reaction.More than half of the reaction heat of Al powders is used to heat itself,whereas the gas consumption during the reaction is negligible. 展开更多
关键词 Aluminized explosive Detonation products EOS Rod-driven test Compositional evolution
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Experimental study of Al agglomeration on solid propellant burning surface and condensed combustion products 被引量:1
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作者 Cheng-yin Tu Xiong Chen +2 位作者 Ying-kun Li Bei-chen Zhang Chang-sheng Zhou 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第8期111-122,共12页
Aluminum(Al) particles are commonly added to energetic materials including propellants,explosives and pyrotechnics to increase the overall energy density of the composite,but aluminum agglomeration on the combustion s... Aluminum(Al) particles are commonly added to energetic materials including propellants,explosives and pyrotechnics to increase the overall energy density of the composite,but aluminum agglomeration on the combustion surface may lower the combustion efficiency of propellants,resulting in a loss in twophase flow.Therefore,it is necessary to understand the agglomeration mechanism of aluminum particles on the combustion surface.In this paper,a high-pressure sealed combustion chamber is constructed,and high-speed camera is used to capture the whole process of aluminum accumulation,aggregation and agglomeration on the combustion surface,and the secondary agglomeration process near the combustion surface.The microscopic morphology and chemical composition of the condensed combustion products(CCPs) are then studied by using scanning electron microscopy coupled with energy dispersive(SEM-EDS) method.Results show that there are three main types of condensed combustion products:small smoke oxide particles oxidized by aluminum vapor,usually less than 1 μm;typical agglomerates formed by the combustion of aluminum agglomerates;carbonized agglomerates that are widely distributed,usually formed by irregular movements of aluminum agglomerates.The particle size of condensed combustion products is measured by laser particle size meter.As the pressure increases from 0.5 MPa to 1.0 MPa in nitrogen,the mass average particle size of aluminum agglomerates decreases by 49.7%.As the ambient gas is changed from 0.5 MPa nitrogen to 0.5 MPa air,the mass average particle size of aluminum agglomerates decreases by 67.3%.Results show that as the ambient pressure increases,the higher oxygen content can improve combustion efficiency and reduce the average agglomeration size of aluminum particles. 展开更多
关键词 Solid propellant Al particles Condensed combustion products AGGLOMERATION Microscopic morphology
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