The clinical effects of two different methods–high-viscosity cement percutaneous vertebroplasty（PVP） and low-viscosity cement percutaneous kyphoplasty（PKP） in the treatment of osteoporotic vertebral compression f...The clinical effects of two different methods–high-viscosity cement percutaneous vertebroplasty（PVP） and low-viscosity cement percutaneous kyphoplasty（PKP） in the treatment of osteoporotic vertebral compression fractures（OVCFs） were investigated. From June 2010 to August 2013, 98 cases of OVCFs were included in our study. Forty-six patients underwent high-viscosity PVP and 52 patients underwent low-viscosity PKP. The occurrence of cement leakage was observed. Pain relief and functional activity were evaluated using the Visual Analog Scale（VAS） and Oswestry Disability Index（ODI）, respectively. Restoration of the vertebral body height and angle of kyphosis were assessed by comparing preoperative and postoperative measurements of the anterior heights, middle heights and the kyphotic angle of the fractured vertebra. Nine out of the 54 vertebra bodies and 11 out of the 60 vertebra bodies were observed to have cement leakage in the high-viscosity PVP and low-viscosity PKP groups, respectively. The rate of cement leakage, correction of anterior vertebral height and kyphotic angles showed no significant differences between the two groups（P〉0.05）. Low-viscosity PKP had significant advantage in terms of the restoration of middle vertebral height as compared with the high-viscosity PVP（P〈0.05）. Both groups showed significant improvements in pain relief and functional capacity status after surgery（P〈0.05）. It was concluded that high-viscosity PVP and low-viscosity PKP have similar clinical effects in terms of the rate of cement leakage, restoration of the anterior vertebral body height, changes of kyphotic angles, functional activity, and pain relief. Low-viscosity PKP is better than high-viscosity PVP in restoring the height of the middle vertebra.展开更多
目的回顾性分析初次全膝关节置换术的合适病例,探讨抗生素骨水泥的应用是否可以降低其术后感染率。方法对1994年至2009年本组所有接受初次全膝关节置换术的患者按是否使用抗生素骨水泥分为两组,分析年龄、性别、BMI、糖尿病、基础疾病、...目的回顾性分析初次全膝关节置换术的合适病例,探讨抗生素骨水泥的应用是否可以降低其术后感染率。方法对1994年至2009年本组所有接受初次全膝关节置换术的患者按是否使用抗生素骨水泥分为两组,分析年龄、性别、BMI、糖尿病、基础疾病、HSS评分、手术时间的差别,对其中的差异项目进行Logistic回归分析以找出影响TKA术后感染的因素,并对感染病例进行感染时间、致病菌、药敏结果等分析。结果抗生素骨水泥组相比于非抗生素骨水泥组,其感染率方面并无统计学差异(8/945 vs 5/701,x2=0.0913,P>0.05)。相关性Logistic回归分析显示抗生素骨水泥应用并不能降低感染率[OR=1.241,95%CI(0.402,3.834),x2=0.140,P>0.05]。13例感染病例分析表明,凝固酶阴性葡萄球菌(CNS)占38%,传统的金黄色葡萄球菌(SA)仅占23%,临床常用的庆大霉素骨水泥无法完全覆盖。结论对抗生素骨水泥的使用仍应保持审慎的态度,避免过度使用造成的医疗资源浪费以及抗生素相关并发症发生率的增加。展开更多
基金supported by Development Center for Medical Science and Technology,National Health and Family Planning Commission of China(No.W2012ZT15)
文摘The clinical effects of two different methods–high-viscosity cement percutaneous vertebroplasty（PVP） and low-viscosity cement percutaneous kyphoplasty（PKP） in the treatment of osteoporotic vertebral compression fractures（OVCFs） were investigated. From June 2010 to August 2013, 98 cases of OVCFs were included in our study. Forty-six patients underwent high-viscosity PVP and 52 patients underwent low-viscosity PKP. The occurrence of cement leakage was observed. Pain relief and functional activity were evaluated using the Visual Analog Scale（VAS） and Oswestry Disability Index（ODI）, respectively. Restoration of the vertebral body height and angle of kyphosis were assessed by comparing preoperative and postoperative measurements of the anterior heights, middle heights and the kyphotic angle of the fractured vertebra. Nine out of the 54 vertebra bodies and 11 out of the 60 vertebra bodies were observed to have cement leakage in the high-viscosity PVP and low-viscosity PKP groups, respectively. The rate of cement leakage, correction of anterior vertebral height and kyphotic angles showed no significant differences between the two groups（P〉0.05）. Low-viscosity PKP had significant advantage in terms of the restoration of middle vertebral height as compared with the high-viscosity PVP（P〈0.05）. Both groups showed significant improvements in pain relief and functional capacity status after surgery（P〈0.05）. It was concluded that high-viscosity PVP and low-viscosity PKP have similar clinical effects in terms of the rate of cement leakage, restoration of the anterior vertebral body height, changes of kyphotic angles, functional activity, and pain relief. Low-viscosity PKP is better than high-viscosity PVP in restoring the height of the middle vertebra.
文摘目的回顾性分析初次全膝关节置换术的合适病例,探讨抗生素骨水泥的应用是否可以降低其术后感染率。方法对1994年至2009年本组所有接受初次全膝关节置换术的患者按是否使用抗生素骨水泥分为两组,分析年龄、性别、BMI、糖尿病、基础疾病、HSS评分、手术时间的差别,对其中的差异项目进行Logistic回归分析以找出影响TKA术后感染的因素,并对感染病例进行感染时间、致病菌、药敏结果等分析。结果抗生素骨水泥组相比于非抗生素骨水泥组,其感染率方面并无统计学差异(8/945 vs 5/701,x2=0.0913,P>0.05)。相关性Logistic回归分析显示抗生素骨水泥应用并不能降低感染率[OR=1.241,95%CI(0.402,3.834),x2=0.140,P>0.05]。13例感染病例分析表明,凝固酶阴性葡萄球菌(CNS)占38%,传统的金黄色葡萄球菌(SA)仅占23%,临床常用的庆大霉素骨水泥无法完全覆盖。结论对抗生素骨水泥的使用仍应保持审慎的态度,避免过度使用造成的医疗资源浪费以及抗生素相关并发症发生率的增加。
