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基于数据流的K-S变化检测的动态多目标规划算法 被引量:1
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作者 张涛 周晨 +2 位作者 杜锋 陈芳 刘瑞林 《长江大学学报(自然科学版)》 2024年第1期109-116,共8页
为了更加准确地判断环境是否发生变化并快速追踪动态多目标规划问题(dynamicmulti-objectiveoptimization problem,DMOP)当前时刻的Pareto前沿,提出了一种基于数据流的Kolmogorov-Smirnov(K-S)变化检测的动态多目标规划(DSK-SDMOP)算法... 为了更加准确地判断环境是否发生变化并快速追踪动态多目标规划问题(dynamicmulti-objectiveoptimization problem,DMOP)当前时刻的Pareto前沿,提出了一种基于数据流的Kolmogorov-Smirnov(K-S)变化检测的动态多目标规划(DSK-SDMOP)算法。该算法以NSGA-Ⅱ为基础,通过数据流建立2个时刻的检验窗口,再利用K-S检验基于数据流的Pareto最优前沿是否发生变化,检测2个窗口的数据是否服从同一分布来判断环境是否发生变化,并就环境变化的剧烈程度实行相应的应答机制,以提高对环境的适应程度。利用基于数据流的K-S检测方法,对环境变化不会过于敏感,而且不用提前假设对应目标值的分布,易于操作。通过5个动态多目标规划标准测试函数对该算法进行测试,并和现有的2种算法进行对比分析,结果表明该算法处理动态多目标规划问题具有良好的性能。 展开更多
关键词 动态多目标规划 数据流 K-s检验 NsGA-Ⅱ
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基于MRI影像组学构建PD-1/PD-L1抑制剂治疗dMMR/MSI-H直肠癌疗效的预测模型
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作者 张岚 周彦汝 +3 位作者 韩鼎盛 张嘉诚 何旭 刘鹏 《中国医学计算机成像杂志》 CSCD 北大核心 2024年第3期343-348,共6页
目的:探讨MRI影像组学模型在程序性细胞死亡蛋白-1(PD-1)/程序性细胞死亡-配体1(PD-L1)抑制剂联合全程新辅助治疗(TNT)局部进展期直肠癌(LARC)的疗效预测价值。方法:收集河南中医药大学第一附属医院PD-1/PD-L1抑制剂联合TNT治疗的80例... 目的:探讨MRI影像组学模型在程序性细胞死亡蛋白-1(PD-1)/程序性细胞死亡-配体1(PD-L1)抑制剂联合全程新辅助治疗(TNT)局部进展期直肠癌(LARC)的疗效预测价值。方法:收集河南中医药大学第一附属医院PD-1/PD-L1抑制剂联合TNT治疗的80例错配修复基因缺陷(dMMR)/微卫星高度不稳定(MSI-H)基因型中低位LARC患者的临床和影像资料。将入组患者按7∶3比例分为训练集和测试集,提取影像组学特征,从中筛选并构建影像组学模型。描绘影像组学模型的Rad-score与病理金标准之间的受试者工作特征(ROC)曲线,计算曲线下面积(AUC),并评价模型的诊断效能。采用决策曲线分析(DCA)计算风险阈值的范围,并评估临床获益情况。收集湖南省人民医院25例dMMR/MSI-H基因型LARC患者的影像资料作为外部验证集。结果:训练集、测试集及外部验证集三者之间的临床特征无统计学差异(P>0.05)。经过降维处理、t检验及一致性检验以及LASSO交叉验证后,筛选出一阶偏度特征和体积2个特征构建影像组学模型。训练集、测试集和外部验证集的影像组学预测模型ROC曲线的AUC、灵敏度、特异度、阳性预测值和阴性预测值分别为0.920、97.1%、85.7%、91.9%、94.7%;0.885、80.0%、88.9%、92.3%、72.7%;0.875、87.5%、88.9%、93.3%、80.0%。DCA曲线显示,当风险阈值范围为0%~82%时,采用影像组学模型预测LARC患者为病理完全缓解(pCR)的获益大于将所有患者都视为pCR或者无病理完全缓解(npCR)。结论:基于MRI影像组学构建的dMMR/MSI-H型局部进展期直肠癌PD-1/PD-L1抑制剂联合全程新辅助放化疗疗效预测模型,有较大潜力为不同基因分型的直肠癌患者制定个体化治疗策略提供量化依据。 展开更多
关键词 磁共振成像 影像组学 直肠肿瘤 局部进展期 程序性细胞死亡蛋白-1/程序性细胞死亡-配体1 全程新辅助放化疗
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S-烯丙基巯基半胱氨酸促进CD8+T细胞杀伤功能的机制研究
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作者 翟健 李军 《中国耳鼻咽喉头颈外科》 CSCD 2024年第2期74-78,共5页
目的探究S-烯丙基巯基半胱氨酸(S-allylmercaptocysteine,SAMC)对CD8^(+)T细胞杀伤鼻咽癌细胞功能的影响及机制。方法将人鼻咽癌细胞HK-1和C666-1与SAMC共培养,分为0、25、50、100μmol/L SAMC组,Western blot检测肿瘤细胞程序性死亡配... 目的探究S-烯丙基巯基半胱氨酸(S-allylmercaptocysteine,SAMC)对CD8^(+)T细胞杀伤鼻咽癌细胞功能的影响及机制。方法将人鼻咽癌细胞HK-1和C666-1与SAMC共培养,分为0、25、50、100μmol/L SAMC组,Western blot检测肿瘤细胞程序性死亡配体-1(programmed cell death-ligand 1,PD-L1)表达。CD8^(+)T细胞分别与HK-1和C666-1细胞以10∶1的比例共培养并加入0、25、50、100μmol/L SAMC,检测CD8^(+)T对HK-1和C666-1的杀伤能力,酶联免疫法(ELISA)检测干扰素(INF-γ)和肿瘤坏死因子-α(TNF-α)浓度,构建鼻咽细胞HK-1的小鼠皮下移植瘤模型,分为对照组、CD8^(+)T细胞组、SAMC组、SAMC+CD8^(+)T细胞组,各组小鼠治疗期间测量瘤体积,治疗结束后取小鼠肿瘤组织,Western blot检测肿瘤组织中PD-L1表达,ELISA检测小鼠血清INF-γ和TNF-α浓度。结果相比于0μmol/L SAMC组,25、50、100μmol/L SAMC组HK-1和C666-1细胞PD-L1表达均显著下调(P<0.05),相比于0μmol/L SAMC+CD8^(+)T细胞组,25、50、100μmol/L SAMC+CD8^(+)T细胞组HK-1和C666-1细胞培养上清中INF-γ和TNF-α浓度均能显著增加,HK-1和C666-1细胞裂解率显著增加(P<0.01)。相比于对照组,CD8^(+)T细胞组和SAMC+CD8^(+)T细胞组小鼠瘤体积和瘤重显著下降(P<0.05),小鼠血清INF-γ和TNF-α浓度显著增加,相比于CD8^(+)T细胞组,SAMC+CD8^(+)T细胞组小鼠瘤体积和瘤重显著下降(P<0.05),小鼠血清INF-γ和TNF-α浓度显著增加(P<0.05),肿瘤组织PD-L1表达显著下调(P<0.01)。结论SAMC可通过抑制人鼻咽癌细胞PD-L1表达而促进CD8^(+)T细胞的杀伤功能。 展开更多
关键词 鼻咽癌 酶联免疫吸附测定 s-烯丙基巯基半胱氨酸 细胞程序性死亡配体-1
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AR、SKP2、SOX10、PD-L1及TIL表达在三阴性乳腺癌中的意义
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作者 刘娟 殷丽娟 范德生 《诊断学理论与实践》 2024年第2期162-172,共11页
目的:探索雄激素受体(androgen receptor,AR)、S期激酶相关蛋白2(S-phase kinase-associated protein 2,SKP2)、性别决定区Y相关的HMG盒含因子10(sry-related HMG box-containing factor 10,SOX10)、程序性死亡配体1(programmed death-l... 目的:探索雄激素受体(androgen receptor,AR)、S期激酶相关蛋白2(S-phase kinase-associated protein 2,SKP2)、性别决定区Y相关的HMG盒含因子10(sry-related HMG box-containing factor 10,SOX10)、程序性死亡配体1(programmed death-ligand 1,PD-L1)及肿瘤浸润性淋巴细胞(tumor infiltrating lymphocyte,TIL)在三阴性乳腺癌(triple negative breast cancer,TNBC)表达与临床病理特征和预后的关系。方法:根据苏木精-伊红染色(hematoxylineosin, HE)染色切片评判109例TNBC瘤巢内TIL的比例,采用Leica Bond-Max全自动免疫组化仪检测TNBC组织中AR、SKP2、SOX10、PD-L1的表达。分析以上各生物指标与临床病理特征间的关系,并采用kaplan-Meier、Log-rank进行生存分析。结果:95例患者获得随访,中位随访时间为48个月,中位无病生存时间(disease-free survival, DFS)为42个月,中位总生存时间(overall survival, OS)48个月。在TNBC中,AR阳性表达与淋巴结转移阴性(P=0.009)、肿瘤最大径<2 cm(P=0.008)相关,TIL高表达与低级别TNBC相关(P=0.007),SKP2阳性表达与神经/脉管侵犯阳性(P=0.011)、高级别TNBC相关(P=0.002),SOX10阳性表达与淋巴结转移阳性(P=0.022)、高级别TNBC(P=0.005)相关,PD-L1阳性表达与淋巴结转移阳性(P=0.020)、神经/脉管侵犯阳性(P=0.006)、高级别TNBC(P=0.042)相关。生存分析显示,SKP2、SOX10阳性表达与更差的DFS(P=0.007、P<0.001)和OS(P=0.013、P<0.001)相关,TIL高表达与更好的DFS(P=0.016)及OS(P=0.004)相关。在生物表志物的联合表达中,AR+/SKP2-、AR+/SOX10-与更好的DFS(P=0.004、P<0.001)及OS(P=0.007、P=0.001)相关,SOX10+/低TIL、PD-L1+/低TIL与更差的DFS(P<0.001、P=0.008)及OS(P=0.001、P=0.002)相关,AR-/低TIL者具有更差的OS(P=0.014)。SKP2(HR=4.143,95%CI为1.578~10.875)、SOX10(HR=7.578,95%CI为2.067~27.782)的阳性表达是影响TNBC患者DFS的独立预后因子,SKP2(HR=3.758,95%CI为1.400~10.084)、SOX10(HR=5.131,95%CI为1.316~20.000)及TIL(HR=0.375,95%CI为0.154~0.917)的阳性表达是TNBC患者OS的独立预后因子(P均<0.05)。结论:在TNBC中,AR阳性、TIL高表达与具有更好预后的临床病理特征相关,SKP2、SOX10和PD-L1与具侵袭性的临床病理特征相关。SKP2、SOX10及TIL表达与TNBC预后相关,提示这些生物指标可能成为TNBC新的预后因子,同时它们也有可能成为潜在的治疗靶点。 展开更多
关键词 三阴性乳腺癌 雄激素受体 s期激酶相关蛋白2 性别决定区Y相关的HMG盒含因子10 程序性死亡配体1 肿瘤浸润性淋巴细胞
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Prevalence of vegetation browning in China’s drylands under climate change 被引量:1
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作者 Li Fu Guolong Zhang +3 位作者 Jianping Huang Ming Peng Lei Ding Dongliang Han 《Geography and Sustainability》 CSCD 2024年第3期405-414,共10页
Vegetation greening has long been acknowledged,but recent studies have pointed out that vegetation greening is possibly stalled or even reversed.However,detailed analyses about greening reversal or increased browning ... Vegetation greening has long been acknowledged,but recent studies have pointed out that vegetation greening is possibly stalled or even reversed.However,detailed analyses about greening reversal or increased browning of vegetation remain scarce.In this study,we utilized the normalized difference vegetation index(NDVI)as an indicator of vegetation to investigate the trends of vegetation greening and browning(monotonic,interruption,and reversal)through the breaks for the additive season and trend(BFAST)method across China’s drylands from 1982 to 2022.It also reveals the impacts of ecological restoration programs(ERPs)and climate change on these vegetation trends.We find that the vegetation displays an obvious pattern of east-greening and west-browning in China’s drylands.Greening trends mainly exhibits monotonic greening(29.8%)and greening with setback(36.8%),whereas browning shows a greening to browning reversal(19.2%).The increase rate of greening to browning reversal is 0.0342/yr,which is apparently greater than that of greening with setback,0.0078/yr.This research highlights that,under the background of widespread vegetation greening,vegetation browning is pro-gressively increasing due to the effects of climate change.Furthermore,the ERPs have significantly increased vegetation coverage,with the increase rate in 2000-2022 being twice as much as that of 1982-1999 in reveg-etation regions.Vegetation browning in southwestern Qingzang Plateau is primarily driven by adverse climatic factors and anthropogenic disturbances,which offset the efforts of ERPs. 展开更多
关键词 China’s drylands Ecological restoration programs Climate change Greening to browning reversal BFAsT
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PIC/S技术标准指南体系分析
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作者 颜若曦 《中国药物评价》 2024年第2期172-176,共5页
国家药品监督管理局已于2023年9月正式提交了加入药品检查合作计划(PIC/S)申请并已成为正式申请者。当前,PIC/S针对申请加入机构和制药行业颁发了大量的技术标准与指南,熟悉并掌握这些技术标准指南,有助于药品监管机构和制药行业更有效... 国家药品监督管理局已于2023年9月正式提交了加入药品检查合作计划(PIC/S)申请并已成为正式申请者。当前,PIC/S针对申请加入机构和制药行业颁发了大量的技术标准与指南,熟悉并掌握这些技术标准指南,有助于药品监管机构和制药行业更有效地推进和应对加入PIC/S工作。参考PIC/S网站,本文按照GMP标准、机构指南、指导文件、备忘录和其他文件的分类原则,对PIC/S发布的现行技术标准与指南进行了系统分析与梳理,从体系层面对其进行了研究,以期为业内机构和人员更好地理解PIC/S标准指南体系提供参考。 展开更多
关键词 药品检查 药品检查合作计划 药品生产质量管理规范
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Th1/Th2、CD28、ICOS、PD-1和CTLA-4在桥本甲状腺炎患者外周血中的表达及与甲状腺相关实验室指标的相关性 被引量:6
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作者 罗百文 李茂城 杨丽梅 《检验医学与临床》 CAS 2023年第5期589-593,共5页
目的探讨辅助性T淋巴细胞1与辅助性T淋巴细胞2比值(Th1/Th2)、CD28、可诱导共刺激分子(ICOS)、程序性死亡受体1(PD-1)和细胞毒性T淋巴细胞相关抗原4(CTLA-4)在桥本甲状腺炎(HT)患者外周血中的表达及与甲状腺相关实验室指标的相关性。方... 目的探讨辅助性T淋巴细胞1与辅助性T淋巴细胞2比值(Th1/Th2)、CD28、可诱导共刺激分子(ICOS)、程序性死亡受体1(PD-1)和细胞毒性T淋巴细胞相关抗原4(CTLA-4)在桥本甲状腺炎(HT)患者外周血中的表达及与甲状腺相关实验室指标的相关性。方法收集2021年在该院门诊或住院治疗的HT患者40例为HT组,另选择同期健康体检者40例为对照组。采用全自动化学发光免疫分析仪检测血清甲状腺过氧化物酶抗体(TPOAb)、促甲状腺激素(TSH)、游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)水平,采用酶联免疫吸附试验检测血清γ干扰素(IFN-γ)、白细胞介素(IL)-2、IL-4和IL-10水平,采用流式细胞仪检测外周血中Th1与Th2细胞,以及CD3^(+)CD4^(+)T淋巴细胞表面共信号分子CD28、ICOS、PD-1、CTLA-4水平。结果HT组血清FT4和TPOAb水平均明显高于对照组,TSH、FT3水平明显低于对照组,差异有统计学意义(P<0.05)。HT组外周血中Th1细胞及其相关细胞因子IFN-γ和IL-2水平,以及Th1/Th2明显高于对照组,差异有统计学意义(P<0.05)。HT组外周血CD3^(+)CD4^(+)T淋巴细胞表面CD28、ICOS和PD-1水平明显高于对照组,差异有统计学意义(P<0.05);两组CTLA-4水平比较,差异无统计学意义(P>0.05)。FT4水平与Th1细胞、Th1/Th2水平呈正相关(P<0.05);TSH水平与Th1细胞、Th1/Th2和IL-2水平呈负相关(P<0.05);TPOAb水平与Th1细胞、Th1/Th2、IFN-γ、IL-2、CD28及ICOS水平呈正相关(P<0.05)。结论HT患者外周血中Th1细胞及其相关细胞因子IFN-γ和IL-2水平较健康体检者均明显上调,其CD3^(+)CD4^(+)T淋巴细胞表面CD28、ICOS和PD-1的表达也均明显上调。Th1细胞及其相关细胞因子,以及CD28、ICOS和PD-1可能在HT的发病机制中发挥了重要作用。 展开更多
关键词 桥本甲状腺炎 辅助性T淋巴细胞 CD28 可诱导共刺激分子 程序性死亡受体1 细胞毒性T淋巴细胞相关抗原4
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ON SUFFICIENCY AND DUALITY OF SOLUTIONS FOR QUASI B_s-INVEX SEMI-INFINITE PROGRAMMING 被引量:1
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作者 张庆祥 《Numerical Mathematics A Journal of Chinese Universities(English Series)》 SCIE 2001年第1期37-44,共8页
A class of functions called quasi B s invex and pseudo B s invex functions are introduced by using the concept of symmetric gradient. The examples of quasi B s invex and pseudo B s invex functions are given. The suffi... A class of functions called quasi B s invex and pseudo B s invex functions are introduced by using the concept of symmetric gradient. The examples of quasi B s invex and pseudo B s invex functions are given. The sufficient optimality conditions and Mond Weir type duality results are obtained for a nondifferentiable nonlinear semi infinite programming problem involving quasi B s invex and pseudo B s invex functions. 展开更多
关键词 INVEX quasi B s invex and pseudo B s invex sufficient optimality DUALITY semi infinite programming.
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Scientific Progress in China's Lunar Exploration Program 被引量:1
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作者 XU Lin OUYANG Ziyuan 《空间科学学报》 CAS CSCD 北大核心 2014年第5期525-534,共10页
Chang'E-1, the first lunar mission in China, was successfully launched on October 24,2007, which opened the prelude of China's Lunar Exploration Program. Later on, the Chang'E-2 and Chang'E-3 satellite... Chang'E-1, the first lunar mission in China, was successfully launched on October 24,2007, which opened the prelude of China's Lunar Exploration Program. Later on, the Chang'E-2 and Chang'E-3 satellites were successfully launched in 2010 and 2013, respectively. In order to achieve the science objectives, various payloads boarded the spacecraft. The scientific data from these instruments were received by Beijing and Kunming ground stations simultaneously. Up to now, about 5.628 Terabytes of raw data were received totally. A series of research results has been achieved. This paper presents a brief introduction to the main scientific results and latest progress from Chang'E-3 mission. 展开更多
关键词 China’s LUNAR Exploration program Chang’E satellite sCIENTIFIC REsULT MOON
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基于混合整数线性规划模型的SPONGENTS盒紧凑约束分析 被引量:1
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作者 石一鹏 刘杰 +2 位作者 祖锦源 张涛 张国群 《计算机应用》 CSCD 北大核心 2023年第5期1504-1510,共7页
应用基于混合整数线性规划(MILP)模型的S盒紧凑约束计算方法,可以较好地解决SPONGENT在差分密码分析过程中差分路径搜索效率低下的问题;为寻找S盒的最优描述,提出一种紧凑性验证算法从约束条件存在必要性的角度验证S盒的不等式约束的紧... 应用基于混合整数线性规划(MILP)模型的S盒紧凑约束计算方法,可以较好地解决SPONGENT在差分密码分析过程中差分路径搜索效率低下的问题;为寻找S盒的最优描述,提出一种紧凑性验证算法从约束条件存在必要性的角度验证S盒的不等式约束的紧凑性问题。首先,引入MILP模型分析SPONGENT S盒的不等式约束,得到了由23个不等式组成的约束;然后,提出一种用于评价约束不等式存在必要性的指标,并基于该指标提出了一种验证约束不等式组紧凑程度的紧凑性验证算法;最后,使用所提算法验证所求得的SPONGENT S盒约束的紧凑性。计算分析表明,23个不等式都具有唯一可以排除的不可能差分模式,即每个不等式都有存在的必要性;同时,对于同一案例,与利用贪心算法原理筛选的不等式相比,数量减少了20%。因此,所得到的SPONGENT的S盒不等式约束是紧凑的,且所提紧凑性验证算法的效果要优于对比的贪心算法。 展开更多
关键词 差分密码分析 混合整数线性规划 代换‒置换网络 sPONGENT s
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Fulbright Program: A Bright Facet of Sino-U.S. People-to-People Exchange
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作者 李晓晗 《海外英语》 2015年第19期169-172,共4页
In the history of Chinese-American people-to-people exchange,the implementation of the China-U.S.Fulbright Program is surely a bright facet which should not be ignored.This program has been cultivating talents in the ... In the history of Chinese-American people-to-people exchange,the implementation of the China-U.S.Fulbright Program is surely a bright facet which should not be ignored.This program has been cultivating talents in the fields of social sciences and humanities for the two countries,promoting Sino-U.S.communications in the domains of education,academia and culture,and propelling the diffusion and advance of both Chinese and American cultures.The Fulbright Program in China still has certain limitations waiting to be improved,and one obvious problem is its coverage in China.To solve this problem,more Chinese higher education institutions should be included in the China-U.S.Fulbright Program,and the result would be the generation of immeasurable value for the prosperity of Sino-American people-to-people exchange and therefore the construction of the new model of major country relations between China and the United States. 展开更多
关键词 The China-U s FULBRIGHT program sino-U people-to-people EXCHANGE James William FULBRIGHT talent CULT
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A Semiotic Analysis of Programming Languages
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作者 Ricardo Maciel Gazoni 《Journal of Computer and Communications》 2018年第3期91-101,共11页
The paper presents an analysis of computer programming languages based on the semiotics of Charles S. Peirce. The author describes how such languages could evolve in order to achieve some of the expressive characteris... The paper presents an analysis of computer programming languages based on the semiotics of Charles S. Peirce. The author describes how such languages could evolve in order to achieve some of the expressive characteristics of natural languages. This description evinces otherwise unnoticed differences between natural languages and programming languages, showing that Peircean semiotics is an efficient analysis tool. This suggests further research on the technical features needed to implement an easier way to program computers. 展开更多
关键词 programMING LANGUAGEs NATURAL LANGUAGEs sEMIOTICs Charles s. PEIRCE
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基于B/S架构的勤工助学系统设计与实现 被引量:5
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作者 李欢 王杨俊 万珊 《现代信息科技》 2023年第6期28-30,34,共4页
勤工助学是高校学生资助工作的重要组成部分,是提高学生综合素质和资助家庭经济困难学生的有效途径,是实现全程育人、方位育人的有效平台。将信息技术运用到高校学生勤工助学管理中,不仅能够有效提高管理效率,降低人工成本,还可以更加... 勤工助学是高校学生资助工作的重要组成部分,是提高学生综合素质和资助家庭经济困难学生的有效途径,是实现全程育人、方位育人的有效平台。将信息技术运用到高校学生勤工助学管理中,不仅能够有效提高管理效率,降低人工成本,还可以更加高效地解决贫困生与岗位匹配的问题。因此,文章运用B/S架构模式,结合SSM框架、jsp技术、MySQL数据库和Tomcat服务器,设计并实现了勤工助学系统。并且根据每一个学生需求,使用协同过滤算法,进行个性化岗位推荐,提高岗位的匹配度。 展开更多
关键词 勤工助学 协同过滤算法 B/s架构 MYsQL数据库
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The DNP: Knowledge and perceptions of students in an accelerated master’s program in nursing
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作者 Young-Me Lee Karyn Holm +2 位作者 Elizabeth Florez Megan Glauser Erin Haswell 《Open Journal of Nursing》 2013年第1期138-146,共9页
While the nursing community generally agrees that the Doctorate of Nursing Practice (DNP) degree will strengthen nursing as an academic discipline, there is little known about students’ perceptions of the advanced de... While the nursing community generally agrees that the Doctorate of Nursing Practice (DNP) degree will strengthen nursing as an academic discipline, there is little known about students’ perceptions of the advanced degree. Nursing students enrolled in an accelerated master’s program in nursing (N = 45) were surveyed to assess their knowledge of the DNP degree while also identifying the perceived effect a DNP might have on their careers, on nursing as a discipline, and on public perceptions of nursing practice. In this study, 51% of participants supported the transition to the DNP as the standard degree for practice nursing while 29% were opposed. The majority of participants (71%) planned to pursue an advanced practice nursing degree/certification with 81% of this group signifying that they would do so even if a DNP is required. The majority of participants agreed that the DNP will improve public perception of advanced practice nursing, but 71% thought the title of “doctor” would confuse patients. While current nursing students are generally informed of the upcoming DNP transition, there is disagreement regarding its implications for their careers and for the extent of public understanding. 展开更多
关键词 KNOWLEDGE Perception DNP NURsING students ACCELERATED Master’s program in NURsING
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The 11th Five-Year Program Vs. China's Foreign Trade
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作者 Sun Yongjian 《China's Foreign Trade》 2005年第20期9-10,共2页
关键词 mode high The 11th Five-Year program Vs China’s Foreign Trade Us
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Iranian Nuclear Program and Turkey's Nuclear Nonproliferation Policy
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作者 Ozum Sezin Uzun 《International Relations and Diplomacy》 2015年第6期411-416,共6页
Turkey is a member of several international nonproliferation treaties and organizations. It has supported to prevent proliferation of nuclear weapons and furthermore suggested to establish a nuclear-weapon free zone i... Turkey is a member of several international nonproliferation treaties and organizations. It has supported to prevent proliferation of nuclear weapons and furthermore suggested to establish a nuclear-weapon free zone in the Middle East. In contrast to its nonproliferation policies, it is hosting US tactical nuclear warheads in its own territory. In addition, Turkey's positive stance towards Iranian nuclear program was questioned. Despite the West's warnings and concerns over the Iranian nuclear program, Turkey has supported Iran's right to have a peaceful nuclear program as suggested in the Nonproliferation Treaty. It also opposed to further economic sanctions and military intervention against Iran and endorsed diplomatic solution as the only viable option for convincing Iran to respond fully to the concerns of the international community. Therefore, Turkey welcomed the Geneva Agreement reached by Iran and P5+l. This article argues that the current uncertainties about the Geneva Accord and the comprehensive treaty necessitates Turkey to revise its nonproliferation policies, which should be based on the norm of nonproliferation, rather than the non-use and deterrence norms, in order to suggest long-term and permanent solution to the proliferation of nuclear weapons. 展开更多
关键词 nuclear weapons Iran's nuclear program Geneva Accord Turkey's nonproliferation
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US High-tech Firms Participating In China's 'Tri-gold Program'
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作者 Xiao Qiang 《China's Foreign Trade》 1995年第9期20-20,共1页
The ’tri-gold program’ aiming at improving information exchange for China’s national economy has been put into practice. The ’Gold bridge’ project forms the infrastructure for the information exchange of the nati... The ’tri-gold program’ aiming at improving information exchange for China’s national economy has been put into practice. The ’Gold bridge’ project forms the infrastructure for the information exchange of the national economy. It makes great contributions to the control and decision-making of the country’s macro-economy, to the promotion of social productivity, and to relieving the bottleneck pressure on the parts of energy, communications and environment. The ’Gold Customs’ project aims at realizing paperless foreign trade. The ’Gold card’ project involves modern payment means, such as 展开更多
关键词 GOLD Tri-gold program Us High-tech Firms Participating In China’s HIGH AT
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Spatial Data Process Using Python Script and Visual Programming Language in ArcGIS
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作者 Pil Kwon 《Computer Technology and Application》 2013年第6期275-283,共9页
Data are limitless. But those are usually not formed or created in our needs. Most of data providers deliver their data in Microsoft Excel spreadsheet, which is compatible with ArcGIS, the most widely used GIS (Geogr... Data are limitless. But those are usually not formed or created in our needs. Most of data providers deliver their data in Microsoft Excel spreadsheet, which is compatible with ArcGIS, the most widely used GIS (Geographic Information System) software in GIS sector. However, those table data contain much unnecessary information that do not need for a certain project. Using the raw data can increase processing times and reduce performance of geoprocessing tools. This study shows steps of how the raw data are being processed using ArcGIS ModelBuilder and Python script. 展开更多
关键词 ARCGIs ARCMAP GIs Local Moran's I ModelBuilder PYTHON Python script visual programming language.
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China's Biotech Achievements——Development of China's 863 Program in the Ninth Five-Year Plan Period
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《China's Foreign Trade》 2002年第6期44-45,共2页
Modern biotechnology booms in the molecular life science. It brings about a promising future for improving human health, foodstuff, environment and energy and is of significance to improve traditional agriculture, dru... Modern biotechnology booms in the molecular life science. It brings about a promising future for improving human health, foodstuff, environment and energy and is of significance to improve traditional agriculture, druamakins and other 展开更多
关键词 In China’s Biotech Achievements Development of China’s 863 program in the Ninth Five-Year Plan Period gene
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Forestry Action Program——On China's 21st Century Agenda
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作者 Yan Miao,Staff Reporter 《China's Foreign Trade》 1995年第9期16-17,共2页
Environment and development are important issues of common concern to societies of the contemporary world. They have a direct bearing on the destiny of mankind, as well as the future of the world. Their influence exte... Environment and development are important issues of common concern to societies of the contemporary world. They have a direct bearing on the destiny of mankind, as well as the future of the world. Their influence extends to every country, every people and every individual in this world. Forests are the key and bond to carry out the integration of environment and development. It has become a consensus in international society. Forestry shoulders two missions: optimization of the environment and promotion 展开更多
关键词 Forestry Action program On China’s 21st Century Agenda HIGH
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