Sichuan Province,East Western of China,within the area of east longitude 97°21′-108°31′,north latitude 26°03′-34°19′,which is on the Mediterranean seismic zone;with its complicated geological b...Sichuan Province,East Western of China,within the area of east longitude 97°21′-108°31′,north latitude 26°03′-34°19′,which is on the Mediterranean seismic zone;with its complicated geological background,several strong shocks occurred in this district since ancient times.Earthquake catalogue of this area could date back to B.C.26,however,limited by the conditions—technology or funds,lots of minor earthquake have been lost,which could be展开更多
For a long time,the concept“Nei Wai(内外―center-periphery)”has been used to construct the narrative of the backwarded pre-modern East Asian history.While over emphasizing the effect of the center(Nei),it just simpl...For a long time,the concept“Nei Wai(内外―center-periphery)”has been used to construct the narrative of the backwarded pre-modern East Asian history.While over emphasizing the effect of the center(Nei),it just simply ignored the reactions from the marginal entities(Wai),as ancient China and its neighboring countries’tributary relations could offer us the classic paradigm.In the knowledge world and historical writing records before the establishment of the national states,the period after Vietnam politically independent to China,the most intricate relations between the two countries,or dynasties,we could still find so many similarities of politics and culture in China and Vietnam,which is far beyond the summarized conditions as tributary relations.On the basis of the previous academic construction of Zong Fan relations and applying the research path of decentralization in the view of global history,we can explore and interpret such tributary and diplomatic relations from various perspectives and thus a multi-dimensional,high definition and colorful past of communications between countries is projected to us by the voiceless,motionless,and monotone historical materials.展开更多
Objective:The spectrum and risk of cancer in relatives of BRCA1/2 pathogenic variant carriers in the Chinese population have not been established.Methods:A family history of cancer in 9903 unselected breast cancer pat...Objective:The spectrum and risk of cancer in relatives of BRCA1/2 pathogenic variant carriers in the Chinese population have not been established.Methods:A family history of cancer in 9903 unselected breast cancer patients was retrospectively analyzed.BRCA1/2 status was determined for all patients and relative risks(RRs)were calculated to evaluate cancer risk in relatives of the patients.Results:The incidences of breast cancer in female relatives of BRCA1 carriers,BRCA2 carriers,and non-carriers were 33.0%,32.2%,and 7.7%,respectively.The corresponding incidences of ovarian cancer were 11.5%,2.4%,and 0.5%,respectively.The incidences of pancreatic cancer in male relatives of BRCA1 carriers,BRCA2 carriers,and non-carriers were 1.4%,2.7%,and 0.6%,respectively.The corresponding incidences of prostate cancer were 1.0%,2.1%,and 0.4%,respectively.The risks of breast and ovarian cancers in female relatives of BRCA1 and BRCA2 carriers were significantly higher than female relatives of non-carriers(BRCA1:RR=4.29,P<0.001 and RR=21.95,P<0.001;BRCA2:RR=4.19,P<0.001 and RR=4.65,P<0.001,respectively).Additionally,higher risks of pancreatic and prostate cancers were noted in male relatives of BRCA2 carriers than non-carriers(RR=4.34,P=0.001 and RR=4.86,P=0.001,respectively).Conclusions:Female relatives of BRCA1 and BRCA2 carriers are at increased risk for breast and ovarian cancers,and male relatives of BRCA2 carriers are at increased risk for pancreatic and prostate cancers.展开更多
To study the natural history of dry type of age-related macular degeneration (AMD) and search for a sensitive method for detecting the development of the disease, the fundus fluorescein angiography, visual acuity, ele...To study the natural history of dry type of age-related macular degeneration (AMD) and search for a sensitive method for detecting the development of the disease, the fundus fluorescein angiography, visual acuity, electroretinogram and FM 100-hue test were used to examine 75 eyes, 147 eyes, 73 eyes, and 94 eyes respectively. These examinations were taken at least twice during the follow-up periods. The average age was 63.2 years (50-80 years ). The average follow-up was 29.8 months with a range of 3-74 ...展开更多
We present relative sea level （RSL） curves in Antarctica derived from glacial isostatic adjustment （GIA）predictions based on the melting scenarios of the Antarctic ice sheet since the Last Glacial Maximum （LGM）g...We present relative sea level （RSL） curves in Antarctica derived from glacial isostatic adjustment （GIA）predictions based on the melting scenarios of the Antarctic ice sheet since the Last Glacial Maximum （LGM）given in previous works.Simultaneously,Holocene-age RSL observations obtained at the raised beaches along the coast of Antarctica are shown to be in agreement with the GIA predictions.The differences from previously published ice-loading models regarding the spatial distribution and total mass change of the melted ice are significant.These models were also derived from GIA modelling; the variations can be attributed to the lack of geological and geographical evidence regarding the history of crustal movement due to ice sheet evolution.Next,we summarise the previously published ice load models and demonstrate the RSL curves based on combinations of different ice and earth models.The RSL curves calculated by GIA models indicate that the model dependence of both the ice and earth models is significantly large at several sites where RSL observations were obtained.In particular,GIA predictions based on the thin lithospheric thickness show the spatial distributions that are dependent on the melted ice thickness at each sites.These characteristics result from the short-wavelength deformation of the Earth.However,our predictions strongly suggest that it is possible to find the average ice model despite the use of the different models of lithospheric thickness.By sea level and crustal movement observations,we can deduce the geometry of the post-LGM ice sheets in detail and remove the GIA contribution from the crustal deformation and gravity change observed by space geodetic techniques,such as GPS and GRACE,for the estimation of the Antarctic ice mass change associated with recent global warming.展开更多
In order to understand the historical origins of encircling the cities from the rural areas implemented by the Communist Party of China and the current dual structures of urban and rural development, urban-rural diffe...In order to understand the historical origins of encircling the cities from the rural areas implemented by the Communist Party of China and the current dual structures of urban and rural development, urban-rural differences are analyzed from the four aspects of production mode, management mode, culture and social division of labor. Industrial development in modern times has promoted the modernization of urban production in China. But the rural areas still maintain their traditional self-sufficient natural economy. After the Opium War, the process of modernization of city politics is promoted by more economic elements of capitalism and the formation of Chinese bourgeoisie. During the management of urban modernization, rural areas still adopt the traditional self-management mode. In the aspect of culture, city is the center of development, having large population, developed traffic, and prosperous culture. But the village is lack of information and its culture is relatively backward. In modern times, affected by the foreign capitalist, urban area has become the center of modern productivity. After separating from agriculture, handicraft industry has transferred into urban areas and the social division of labor in both urban and rural areas has shown great changes. Thus, a new pattern of "Urban Industry, Rural Agriculture" has formed.展开更多
The mass-energy equation ?is derived in general from Newton’s equation of motion without use of electrodynamics, or Einstein’s Postulates which were presented in his superb 1905 paper on Special Relativity (SR). Thi...The mass-energy equation ?is derived in general from Newton’s equation of motion without use of electrodynamics, or Einstein’s Postulates which were presented in his superb 1905 paper on Special Relativity (SR). This was previously not thought to be possible. This novel derivation of an accelerated body of rest mass m0 is compared with the traditional SR inertial derivation. A discussion is given of pre-1905, electrostatic and electrodynamic derivations of the mass-energy relation yielding , as well as more recent ones. A concise pre-relativity history of the mass-energy relation is traced back to Newton in 1717.展开更多
文摘Sichuan Province,East Western of China,within the area of east longitude 97°21′-108°31′,north latitude 26°03′-34°19′,which is on the Mediterranean seismic zone;with its complicated geological background,several strong shocks occurred in this district since ancient times.Earthquake catalogue of this area could date back to B.C.26,however,limited by the conditions—technology or funds,lots of minor earthquake have been lost,which could be
文摘For a long time,the concept“Nei Wai(内外―center-periphery)”has been used to construct the narrative of the backwarded pre-modern East Asian history.While over emphasizing the effect of the center(Nei),it just simply ignored the reactions from the marginal entities(Wai),as ancient China and its neighboring countries’tributary relations could offer us the classic paradigm.In the knowledge world and historical writing records before the establishment of the national states,the period after Vietnam politically independent to China,the most intricate relations between the two countries,or dynasties,we could still find so many similarities of politics and culture in China and Vietnam,which is far beyond the summarized conditions as tributary relations.On the basis of the previous academic construction of Zong Fan relations and applying the research path of decentralization in the view of global history,we can explore and interpret such tributary and diplomatic relations from various perspectives and thus a multi-dimensional,high definition and colorful past of communications between countries is projected to us by the voiceless,motionless,and monotone historical materials.
基金supported by grants from National Natural Science Foundation of China(Grant Nos.81974422,81772824,and 81802635)。
文摘Objective:The spectrum and risk of cancer in relatives of BRCA1/2 pathogenic variant carriers in the Chinese population have not been established.Methods:A family history of cancer in 9903 unselected breast cancer patients was retrospectively analyzed.BRCA1/2 status was determined for all patients and relative risks(RRs)were calculated to evaluate cancer risk in relatives of the patients.Results:The incidences of breast cancer in female relatives of BRCA1 carriers,BRCA2 carriers,and non-carriers were 33.0%,32.2%,and 7.7%,respectively.The corresponding incidences of ovarian cancer were 11.5%,2.4%,and 0.5%,respectively.The incidences of pancreatic cancer in male relatives of BRCA1 carriers,BRCA2 carriers,and non-carriers were 1.4%,2.7%,and 0.6%,respectively.The corresponding incidences of prostate cancer were 1.0%,2.1%,and 0.4%,respectively.The risks of breast and ovarian cancers in female relatives of BRCA1 and BRCA2 carriers were significantly higher than female relatives of non-carriers(BRCA1:RR=4.29,P<0.001 and RR=21.95,P<0.001;BRCA2:RR=4.19,P<0.001 and RR=4.65,P<0.001,respectively).Additionally,higher risks of pancreatic and prostate cancers were noted in male relatives of BRCA2 carriers than non-carriers(RR=4.34,P=0.001 and RR=4.86,P=0.001,respectively).Conclusions:Female relatives of BRCA1 and BRCA2 carriers are at increased risk for breast and ovarian cancers,and male relatives of BRCA2 carriers are at increased risk for pancreatic and prostate cancers.
文摘To study the natural history of dry type of age-related macular degeneration (AMD) and search for a sensitive method for detecting the development of the disease, the fundus fluorescein angiography, visual acuity, electroretinogram and FM 100-hue test were used to examine 75 eyes, 147 eyes, 73 eyes, and 94 eyes respectively. These examinations were taken at least twice during the follow-up periods. The average age was 63.2 years (50-80 years ). The average follow-up was 29.8 months with a range of 3-74 ...
基金supported by JSPS KAKENHI grant numbers 23501255,21253001
文摘We present relative sea level （RSL） curves in Antarctica derived from glacial isostatic adjustment （GIA）predictions based on the melting scenarios of the Antarctic ice sheet since the Last Glacial Maximum （LGM）given in previous works.Simultaneously,Holocene-age RSL observations obtained at the raised beaches along the coast of Antarctica are shown to be in agreement with the GIA predictions.The differences from previously published ice-loading models regarding the spatial distribution and total mass change of the melted ice are significant.These models were also derived from GIA modelling; the variations can be attributed to the lack of geological and geographical evidence regarding the history of crustal movement due to ice sheet evolution.Next,we summarise the previously published ice load models and demonstrate the RSL curves based on combinations of different ice and earth models.The RSL curves calculated by GIA models indicate that the model dependence of both the ice and earth models is significantly large at several sites where RSL observations were obtained.In particular,GIA predictions based on the thin lithospheric thickness show the spatial distributions that are dependent on the melted ice thickness at each sites.These characteristics result from the short-wavelength deformation of the Earth.However,our predictions strongly suggest that it is possible to find the average ice model despite the use of the different models of lithospheric thickness.By sea level and crustal movement observations,we can deduce the geometry of the post-LGM ice sheets in detail and remove the GIA contribution from the crustal deformation and gravity change observed by space geodetic techniques,such as GPS and GRACE,for the estimation of the Antarctic ice mass change associated with recent global warming.
基金Supported by the Project of Shaanxi Social Science Foundation(08JK091)
文摘In order to understand the historical origins of encircling the cities from the rural areas implemented by the Communist Party of China and the current dual structures of urban and rural development, urban-rural differences are analyzed from the four aspects of production mode, management mode, culture and social division of labor. Industrial development in modern times has promoted the modernization of urban production in China. But the rural areas still maintain their traditional self-sufficient natural economy. After the Opium War, the process of modernization of city politics is promoted by more economic elements of capitalism and the formation of Chinese bourgeoisie. During the management of urban modernization, rural areas still adopt the traditional self-management mode. In the aspect of culture, city is the center of development, having large population, developed traffic, and prosperous culture. But the village is lack of information and its culture is relatively backward. In modern times, affected by the foreign capitalist, urban area has become the center of modern productivity. After separating from agriculture, handicraft industry has transferred into urban areas and the social division of labor in both urban and rural areas has shown great changes. Thus, a new pattern of "Urban Industry, Rural Agriculture" has formed.
文摘The mass-energy equation ?is derived in general from Newton’s equation of motion without use of electrodynamics, or Einstein’s Postulates which were presented in his superb 1905 paper on Special Relativity (SR). This was previously not thought to be possible. This novel derivation of an accelerated body of rest mass m0 is compared with the traditional SR inertial derivation. A discussion is given of pre-1905, electrostatic and electrodynamic derivations of the mass-energy relation yielding , as well as more recent ones. A concise pre-relativity history of the mass-energy relation is traced back to Newton in 1717.
