Hollow nanospheres exhibit unique properties and find a wide interest in several potential applications such as drug delivery.Herein,novel hollow bioactive glass nanospheres(HBGn)with large hollow cavity and large mes...Hollow nanospheres exhibit unique properties and find a wide interest in several potential applications such as drug delivery.Herein,novel hollow bioactive glass nanospheres(HBGn)with large hollow cavity and large mesopores in their outer shells were synthesized by a simple and facile one-pot ultrasound assisted sol-gel method using PEG as the core soft-template.Interestingly,the produced HBGn exhibited large hollow cavity with ~43 nm in diameter and mesoporous shell of ~37 nm in thickness and 7 nm pore size along with nanosphere size around 117 nm.XPS confirmed the presence of Si and Ca elements at the surface of the HBGn outer shell.Notably,HBGn showed high protein loading capacity(~570 mg of Cyto c per 1 g of HBGn)in addition to controlled protein release over 5 d.HBGn also demonstrated a good in vitro capability of releasing calcium(Ca^(2+):170 ppm)and silicate(SiO_(4)^(4-):78 ppm)ions in an aqueous medium over 2 weeks under physiological-like conditions.Excellent in vitro growth of bone-like hydroxyapatite nanocrystals was exhibited by HBGn during the soaking in SBF.A possible underlying mechanism involving the formation of spherical aggregates(coils)of PEG was proposed for the formation process of HBGn.展开更多
Hollow mesoporous metals have unique potential for catalysis,but their precise synthesis and further elaboration of their structure–performance relationships are still huge challenges.Herein,wereport a new synthetic ...Hollow mesoporous metals have unique potential for catalysis,but their precise synthesis and further elaboration of their structure–performance relationships are still huge challenges.Herein,wereport a new synthetic strategy,named the Kirkendall effect in synergistic template(KEST),for the desired preparation of hollow mesoporous palladium–sulfur(h-mesoPdS)alloy nanoparticles.展开更多
文摘Hollow nanospheres exhibit unique properties and find a wide interest in several potential applications such as drug delivery.Herein,novel hollow bioactive glass nanospheres(HBGn)with large hollow cavity and large mesopores in their outer shells were synthesized by a simple and facile one-pot ultrasound assisted sol-gel method using PEG as the core soft-template.Interestingly,the produced HBGn exhibited large hollow cavity with ~43 nm in diameter and mesoporous shell of ~37 nm in thickness and 7 nm pore size along with nanosphere size around 117 nm.XPS confirmed the presence of Si and Ca elements at the surface of the HBGn outer shell.Notably,HBGn showed high protein loading capacity(~570 mg of Cyto c per 1 g of HBGn)in addition to controlled protein release over 5 d.HBGn also demonstrated a good in vitro capability of releasing calcium(Ca^(2+):170 ppm)and silicate(SiO_(4)^(4-):78 ppm)ions in an aqueous medium over 2 weeks under physiological-like conditions.Excellent in vitro growth of bone-like hydroxyapatite nanocrystals was exhibited by HBGn during the soaking in SBF.A possible underlying mechanism involving the formation of spherical aggregates(coils)of PEG was proposed for the formation process of HBGn.
基金acknowledge the National Key R&D Program of China(no.2018YFE0201701)the Natural Science Foundation of China(grant nos.21975050 and 21771156)+2 种基金the Natural Science Foundation of Jiangsu Province(no.BK20191366)the Open Project of State Key Laboratory of Supramolecular Structure and Materials(no.sklssm2021011)the Fundamental Research Funds for the Central Universities for financial support.
文摘Hollow mesoporous metals have unique potential for catalysis,but their precise synthesis and further elaboration of their structure–performance relationships are still huge challenges.Herein,wereport a new synthetic strategy,named the Kirkendall effect in synergistic template(KEST),for the desired preparation of hollow mesoporous palladium–sulfur(h-mesoPdS)alloy nanoparticles.