Treatment of spinal cord injury with biomaterials and stem cell therapy in non-human primates and humans

Spinal cord injury results in the loss of sensory,motor,and autonomic functions,which almost always produces permanent physical disability.Thus,in the search for more effective treatments than those already applied for years,which are not entirely efficient,researches have been able to demonstrate the potential of biological strategies using biomaterials to tissue manufacturing through bioengineering and stem cell therapy as a neuroregenerative approach,seeking to promote neuronal recovery after spinal cord injury.Each of these strategies has been developed and meticulously evaluated in several animal models with the aim of analyzing the potential of interventions for neuronal repair and,consequently,boosting functional recovery.Although the majority of experimental research has been conducted in rodents,there is increasing recognition of the importance,and need,of evaluating the safety and efficacy of these interventions in non-human primates before moving to clinical trials involving therapies potentially promising in humans.This article is a literature review from databases(PubMed,Science Direct,Elsevier,Scielo,Redalyc,Cochrane,and NCBI)from 10 years ago to date,using keywords(spinal cord injury,cell therapy,non-human primates,humans,and bioengineering in spinal cord injury).From 110 retrieved articles,after two selection rounds based on inclusion and exclusion criteria,21 articles were analyzed.Thus,this review arises from the need to recognize the experimental therapeutic advances applied in non-human primates and even humans,aimed at deepening these strategies and identifying the advantages and influence of the results on extrapolation for clinical applicability in humans.

Bird communities’responses to human-modified landscapes in the southern Anhui Mountainous Area

Conversion of natural environments to human-modified landscapes is continuing at an unprecedented rate,exerting fundamental influences on global biodiversity.Understanding how wildlife communities respond to landscape modifications is critical to improve biodiversity conservation in human-dominated landscapes.In this study,we surveyed bird communities in three common habitats(i.e.,farmland,village,and forest)in the southern Anhui Mountainous Area during summer(August 2019)and winter(December 2020).The diversity metrics and species compositions of the avian communities were compared among the habitats,and the effects of land use composition in these habitats were tested.During the field surveys,we recorded 7599 birds of 120 species along 45 line transects of 1km in length.The land use compositions differed among habitats,and land use diversity was the highest in villages and lowest in forests.The species richness and bird abundance in the two human-dominated habitats(i.e.,farmland and village)were higher than those in forest in both seasons.Bird species composition also differed across habitat types in both seasons.Bird species feeding on vertebrates,fish and carrion,and species feeding on plants and seeds were mainly found in habitats with less construction lands and lower land use diversity,while omnivorous species and species feeding on fruits and nectar or on invertebrates were less affected by these two variables.The indicator species analysis showed that most species associated with forest feed on invertebrates,while species feeding on plants and seeds were more correlated with farmland and village.The results indicated that the conversion of natural habitats to human-dominated landscapes has pronounced impacts on bird communities in the study area.Human-dominated habitats harboured more avian species that deserve conservation attention.Meanwhile,bird conservations should not be relaxed in forests because there were more than 20 species that had a high specificity for forests.

Human Security, Poverty Pattern and Social Order in Igbo Rural Communities of Contemporary Nigeria

The Igbo have their homeland in seven states of Nigeria mainly Imo, Abia, Anambra, Ebonyi, Delta and Rivers. They are receptible to new ideas and adapt easily to change. The ramifications of human insecurity, poverty, social disorder, poor coherence and poor integration appear to haunt them and the gravity is felt more in the rural communities. The factors are traceable to many pathetic issues. The pathological consequences do affect Igbo stability and navigation in the Nigerian socio-economic environment. The causality constitutes the physical, human, natural, financial and social assets. It is recommended, among others, that the people should return to core values and norms, stick to their own noble identities, have a framework for tackling insecurity and hunger, target the youth in poverty reduction measures and tackle the herdsmen menace. Equally, the abused philosophies used to support dangerous and strange behavior should be tackled.

Diversity of root-associated fungi of Rhododendron simsii in subtropical forests: fungal communities with high resistance to anthropogenic disturbances

Species of the Ericaceae or heath family are widely distribute in continental ecosystems and their special ericoid mycorrhizas(ERM)are considered benefi cial to their survival and persistence in variable habitats.Currently,increasing anthropogenic disturbances and improper forest management are aff ecting subtropical forests of China where these native species located.These activities not only aff ect plant communities above-ground,but also impose pressures on microbial communities below-ground.In this study,rootassociated fungal communities of Rhododendron simsii in four forest types under diff erent anthropogenic disturbances were identifi ed using an Illumina Miseq platform,i.e.,old growth forests,secondary forests with one cutting(SECⅠ),secondary forests with two cuttings(SECⅡ),and Chinesefi r plantations(PLF).Intra-and inter-annual variations were analyzed by comparing samples taken in diff erent seasons and years.The results show that:(1)over 1000 OTUs were found in hair roots with most from the division Ascomycota and Basidiomycota belonging to diff erent functional groups;(2)while there were a few indicator OTUs specifi c to diff erent forest types,seasons and years,the proportion of shared taxa was quite large,accounting for 44.9–79.4%of the total OTUs;(3)signifi cantly positive correlations were found between disturbance sensitivity and temporal variations in common fungal orders,and both in major fungal orders were signifi cantly diff erent among fungal functional groups in which putative and possible ERM fungi were highly resistant to disturbances and low temporal variations.The high disturbance resistance and temporal persistence of putative ERM fungi may be essential for the successful adaptation of R.simsii in disturbed subtropical forests of China.

An Exploration of the Three Dimensions and Epochal Strengths of Building a Human Community With a Shared Future

The idea of a human community with a shared future was proposed by the Communist Party of China(CPC)Central Committee with Comrade Xi Jinping at its core for the future development of human beings to face up to the most important question in today's world:“What is happening to the world and what should we do?”It profoundly answers the question of the world,history,and the times.The theory of a human community with a shared future is an innovative theory with a multidimensional formation logic that guides humanity toward continually seeking common interests and values.This paper dives into the profound motivations behind building a human community with a shared future from historical,cultural,and practical dimensions and analyzes its epochal value from both domestic and international perspectives.This not only helps exert China's role in the international community,contributing Chinese strength to the construction of a peaceful,stable,and prosperous human society,but also enhances the influence of the idea of a human community with a shared future in the international community,accelerating the building of a human community with a shared future that considers the legitimate concerns of all countries,and aiding in solving the crises facing the world.

Revisiting the Spirit of the UDHR and Discussing Human Rights Development——Summary of Views from the Seminar Commemorating the 75th Anniversary of the Universal Declaration of Human Rights

On December 4,2023,the China Society for Human Rights Studies hosted a seminar in Beijing commemorating the 75^(th) Anniversary of the Universal Declaration of Human Rights.Participants discussed topics such as the significance of the Universal Declaration of Human Rights,China’s theories and practices in respecting and safeguarding human rights,the three global initiatives and global human rights governance,human rights protection in the digital age,and telling Chinese stories of human rights in the new era.The discussions led to a broad consensus and achieved positive results.

The New Contribution to the Important Discourse on Human Rights by General Secretary xi Jinping

Under the background of the fact that human rights protection has become an important part of the socialist construction with Chinese characteristics in the new era, and with the international background of the strengthened trend of mainstreaming of human rights, Xi Jinping’s series of speeches and the 19 th CPC national Congress reports comprehensively explained the construction of human rights in China and the development of the international human rights. The important discourse on human rights by General Secretary Xi Jinping is people-centered: people’s yearning for a better life is our goal and reveals the source of human rights. Chinese dream is a dream of the country, of the nation, and of everyone in China. The close integration of individual and collective human rights points out that the state and people are important parts of collective human rights and it is an effective response to the "human rights over sovereignty" of Western countries. That there are not the best human rights, but the better ones; fighting for human rights is not always done, but always doing scientifically reveals the operational form of human rights. The right of survival and development is the primary human right; to attach importance to the right of peace conforms to the reality of our country and it has the support of the vast number of developing countries. Building a community with a shared future for human beings is a new vision for the development of the international human rights. only when the perfection and implementation of Constitution and law are paid attention to, and the democratization and legalization of the international human rights cause are promoted, can the guarantee be provided for the realization of human rights. The important discourse on human rights by General Secretary Xi Jinping is guided by Marxism, carries the communist party member’s original intention of serving people and is deeply rooted in the masses of the people. It inherits the theory of "benevolence" and "harmony" in Chinese culture,stands at the height of history and times, and points out the direction for the all-round development of Chinese people and the overall progress of society, and for the liberation of all mankind. This scientific theory is successfully guiding China’s human rights construction constantly towards new achievements and has had a profound and extensive impact on the international human rights cause.

A Community with a Shared Future for Human Beings in the Vision of Modernization of Global Governance: China's Expression and Practice

The human rights cause in the world still faces structural challenges and crises, the factor of which including scarcity of living material resources, global environmental crisis and global terrorism. However, the existing global governance model and governance pattern have made it difficult to deal effectively with the above structural challenges and crises facing the development of human rights in the world. Therefore, it’s necessary to advance and modernize global governance. In order to realize these ends, the Chinese government presents the ideal of a Community with a Shared Future for Human Beings as the modernization of global governance and the Belt and Road Initiative as the proper project for this process of modernization. It calls on all countries to work hand in hand and work together to build a community with a shared future for mankind so as to realize the modernization of global governance and hence the comprehensive development of human beings.

Philosophical Implications of “A Community of Shared Future for Humanity”

A new concept contributing to global governance in the era of globalization,“A Community of Shared Future for Humanity(CSFH)”boasts rich philosophical implications and values connotations despite insufficient research toward it in academia.This study seeks to analyze the philosophical significance of CSFH and concludes that it is a new practice of Marxist“Anthropological Philosophy”,a reserved development of“One Unified World under the Heaven”and“Supreme Harmony Consummated by Coordination of Varied Interests”in traditional Chinese philosophy and a dimensional transcendence over the western“self-reliant”national state system.

Alliance of Civilizations for Human Rights and World Community

The notions of human rights and World Community are inseparably related. It is on the basis of mutual trust that we can construct World Community, so it is quite natural that the respect of human rights is the basic condition of the participant countries. The World Community is aiming at making a peaceful global village where the lives of people are mutually encouraged and the diverse merits of different civilizations are shared together. True human welfare should imply in its concept harmony between all existences. In the history of the world, we can see the irresistible current moving towards the realization of human rights and World Community. Even if we accept this affirmative development of history in the long run, we should be always alert to the dangers and traps on the road. There have been many cases of frustration and reversion by strong counteractions or self-deceptions. In the actual situation of its age, humanity has been always at the crossroads. It is the duty of philosophy and history to shed light on the situation and present a direction.

CONSTRUCTION OF A COMMUNITY OF SHARED FUTURE FOR HUMANKIND IN THE CONTEXT OF AN EMERGING NEW WORLD ORDER

It is the first time in human history that nations of the global south have a position beyond that of victims within international system. Positioning of the developing countries at the contested international system reveals no intentions of dominance or subordination of the less fortunate. Instead, the aim is to complement already existing human achievements to establish a community of shared future for humanity.

Human Rights and Whole-Process People’s Democracy

Other than global economic and social imbalances,and climate change,human rights are the most important challenge for the international community.If our group can articulate the“Shared Human Values”of Human Rights,and can array the“Diversified International Approaches”—in this forum and in future forum—we will have made a vital contribution to China’s role in the world,and to the wellbeing of the entire world.I look forward to contributing.

Human Care Theory and Influences on the Life Quality Index of Cancer Patients in Household Life

To investigatetheinfluences of the application of human care theory on the life quality and happiness of cancer patients after they receiveda community nursing care which was implemented by the human care theory. The quality life and the happiness index of 93 patients with cancer living in the six communities in Jillin were assessed, the assessment of the life quality was based on a life quality scale (SF-36) and that of the happiness index was based on Memorial University of Newfoundland Scale of Happiness (MUNSH). The community nurses cared for these patients by applying the theory of human care and the life quality and the happiness index of the patients were observed after the care. The results showed that there were significant differences in the score of 5 dimensions in the eight dimensions of the life quality between before the care and after the care (<0.05), and there were significant differences in the average sores of the positive emotion, positive experience, negative emotion, negative experience and level of happiness included in the happiness index between before the care and after the care (<0.05), suggesting that the theory of human care can be used for the care of patients with cancer and the application of the theory can effectively improve the life quality and the happiness index of the patients, strengthen their problem-solving abilities and let them have a positive attitude towards their lives.

Building International Consensus and Working Together to Advance the Development of the Global Human Rights Cause—Summary of Academic Views at the Forum on Global Human Rights Governance

On June 14-15,2023,the Forum on Global Human Rights Governance,jointly hosted by the State Council Information Office,the Ministry of Foreign Affairs,and the China International Development Cooperation Agency,was held in Beijing under the theme of“Equality,Cooperation and Development:The 30th Anniversary of the Vienna Declaration and Programme of Action and Global Human Rights Governance.”Participants conducted in-depth discussions and exchanges on topics such as“International Cooperation and Global Human Rights Governance,”“Global Development Initiative and the Realization of the Right to Development”,“Global Security Initiative and Human Rights Protection,”“UN Human Rights Mechanisms and Global Human Rights Governance,”and“Human Rights Protection in the Digital Age.”The event helped build international consensus and yielded fruitful achievements.

The Contribution, Experience and Risk Control of Social Organizations’ Participation in Global Human Rights Governance

As the"third sector",social organizations are increasingly involved in human rights affairs in the era of governance through cooperation.They play an important role in the construction of a human rights community with the core of"common human values",and together with the government and other relevant subjects,they become the guarantors of human rights.By sorting out the main contributions of social organizations and successful experiences participating in human rights governance,it can be seen that they timely support relevant policies and laws and the participation through certain modes are successful experiences of social organizations in participating in human rights governance.Under the guarantee of the mechanism of effectiveness and risk control along the whole chain before,during and after the process,these contributions and experience will provide better Chinese experience and Chinese programs to promote global human rights governance and the progress of human rights cause in the world.

Building a Community with a Shared Future for Mankind to Human Rights Theory

The concept named "a community with a shared future for mankind" has important implications for the theory and practice of human rights. From the perspective of specific human rights, the idea of a Community with a Shared Future for Mankind implies recognizing the right to peace of mankind, advocates the mode of economic cooperation and development, and acts as a guide for building an eco-friendly world, rejecting hegemony, and promoting cultural diversity. Therefore, a Community with a Shared Future for Mankind plays an important supporting role in establishing the legitimacy of specific rights. Meanwhile, in view of the scarcity of human resources, it is impossible for all kinds of rights to be protected to the same degree. Human rights need to be systematically constructed in theory and practice, and also require the formation of a well-functioning platform for their protection. As a guideline, the notion of a Community with a Shared Future for Mankind is conducive to the establishment of such a system.

From the UN Charter and the Universal Declaration of Human Rights to Building a Community with a Shared Future for Human Beings--The Past, Present, and Future of International Human Rights Protection

The UN Charter first of all affirmed the basic concept of international protection of human rights and opened up a broad space for international protection of human rights. The Universal Declaration of Human Rights is an important document in the development of the international human rights cause. It established a set of international standards for basic human rights, represents the world’s most important consensus on human rights, and contributes greatly to the creation of an international human rights legal system. The important theory put forward by President Xi Jinping to build a Community with a Shared Future for Human Beings, as a Chinese program for today s global major issues, also outlines a new blueprint for national human rights protection and will play a major role in promoting the development of China’s human rights and international human rights protection.

The Logic of Change of the CPC’s Human Rights Discourse Since the Founding of the People’s Republic of China

Since the founding of the People’s Republic of China70 years ago,the human rights discourse of the Communist Party of China has been constantly updated.In the early years of the founding of the People’s Republic of China,the CPC spontaneously formed a collective discourse on human rights with the right to subsistence and self-determination as its core;in the 1980 s,in the process of reflection and refutation,the CPC paid more attention to individual rights,and gradually increased the sense of a human rights discourse with Chinese characteristics;since the 1990s,the CPC has combined the specific national conditions and the international environment to form a human rights discourse.The system of human rights discourse has been constructed in terms of the order of priority of human rights protection,path of human rights development,relationship between human rights and sovereignty,and development of the world human rights cause.Since the 18th National Congress of the CPC,the CPC has put forward the idea that"living a happy life is the primary human right"at home and the idea of building a Community with a Shared Future for Human Beings for the world,and the discourse system of human rights with Chinese characteristics has gradually been improved.The independent variable of the change of human rights discourse of the CPC is the specific national conditions at different stages and the recognition of national identity formed on this basis.The other variable is the international environment and external relations that China is facing.

Concept of building a Community with a Shared Future for Human beings and International Cooperation on Pandemic Prevention and Control——Global Pandemic Prevention and Control and Human rights Protection the Second Session of the Series of international S

The global outbreak of COVID-19 has posed a great challenge to the human rights protection.On May 18,2020,the second session of the series of international seminars on"Global Pandemic Prevention and Control and Human Rights Protection",organized by the Institute of Human Rights of China University of Political Science and Law under the guidance of the China Society for Human Rights Studies,was held online.The seminar was themed on the Concept of Building a Community with a Shared Future for Human Beings and International Cooperation on Pandemic Prevention and Control."Through the seminr,Chinese and foreign experts discussed in depth the values of human rights theories,the specific practices and measures taken by China and the European Union in fighting COVID-19,the protection of human rights in emergencies and the issue of human rights derogation.The seminar delivered a general consensus that prejudice should be abandoned in public health emergencies and international cooperation is continuously promoted within the framework of the United Nations to build a community with a shared future for human beings.

The UN’s Human Rights Mechanisms and China’ Constructive Participation

Through establishing and improving charter-based and treaty-based human rights systems, the United Nations develops and promotes the implementation of human rights standards, urges countries to fulfill their international human rights obligations, and provides a platform for countries and other stakeholders to communicate and cooperate in promoting and protecting human rights There are also other UN agencies and entities involved in human rights promotion in different areas As one of the UN’s founding members and the security Council’s permanent members, China has been elected to the Human Rights Council multiple times and has been participating actively in the Universal Periodic Review process, fulfilling obligations under international human rights treaties, expanding cooperation for mutual benefits in the field of human rights, and promoting the concept of a community with a shared future for human beings At both the domestic and international levels, China can, from both domestic and international levels, further strengthen the implementation of international human rights treaties, enhance cooperation with the UN’s human rights system and other agencies, and increase China’s voice and influence in the field of human rights in the UN.