The Development of Managerial Assumptions about Human Nature in China： A Tale from Quanzhou

How managers’ knowledge and beliefs of human nature are formed and manifested has not been fully explored in the context of Chinese society going through rapid transition nowadays. And yet this could be the missing link in our discourse on Chinese managers. Based on a qualitative study conducted in Quanzhou, China, this study found certain assumptions of human nature that are deeply embedded in their managers’ intellectual framework, which in turn guide their managerial behaviours in diverse aspects of their work. Unless the managers are prepared to examine their own thoughts, especially those at the sub-conscious level, they would remain prisoners of their own thought, and all the efforts directed at transforming managers would be seriously compromised.

Hepatitis C virus in human B lymphocytes transformed by Epstein-Barr virus in vitro by in situ reverse transcriptase-polymerase chain reaction

AIM: To study persistence and replication of hepatitis C virus (HCV) in patients' peripheral blood mononuclear cells (PBMC) cultured in vitro. METHODS: Epstein Barr virus (EBV) was used to transform the hepatitis C virus from a HCV positive patient to permanent lymphoblastoid cell lines (LCL). Positive and negative HCV RNA strands of the cultured cells and growth media were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) each month. Core and NS5 proteins of HCV were further tested using immunohistochemical SP method and in situ RT-PCR. RESULTS: HCV RNA positive strands were consistently detected the cultured cells for one year. The negative-strand RNA in LCL cells and the positive-strand RNA in supernatants were observed intermittently. Immunohistochemical results medicated expression of HCV NS3 and C proteins in LCL cytoplasm mostly. The positive signal of PCR product was dark blue and mainly localized to the LCL cytoplasm. The RT-PCR signal was eliminated by overnight RNase digestion but not DNase digestion. CONCLUSION: HCV may exist and remain functional in a cultured cell line for a long period.

Systematic and Theoretical Unfolding of Research on Xi Jinping’s Discourses on Respecting and Protecting Human Rights

Xi Jinping’s discourses on respecting and protect-ing human rights stand as a shining example of the sinicization and modernization of Marxist human rights theory,embodying profound theoretical,political,practical,and cultural logic.Existing research has conducted comprehensive and systematic theoretical analysis and academic extractions on the following contents:the core essence in-herent in these important discourses,including the“theory of human rights concepts,”the“theory of human rights paths,”the“theory of human rights practices,”the“theory of human rights protection,”and the“theory of human rights governance,”along with their profound theoretical significance,practical significance,and global signifi-cance.In the future,researchers should emphasize efforts on studying the original texts and understanding the original principles.While focusing on the precision of concepts,the scientific nature of the prop-ositions,the maturity of theoretical systems,and the rigor of internal logic related to Xi Jinping’s discourses on respecting and protecting human rights,researchers should also pay attention to constructing a discourse system on human rights from the dimensions of discourse power,discourse cluster,and discourse field.Researchers should be adept at drawing innovative insights into human rights theory from China’s vibrant human rights practices and the vast masses of people.This approach will facilitate the systematic unfolding,academic trans-formation,and innovative development of Xi Jinping’s discourses on respecting and protecting human rights.

Transplantation of human hepatocytes into tolerized genetically immunocompetent rats

AIM: To determine whether normal genetically immunocompetent rodent hosts could be manipulated to accept human hepatocyte transplants with long term survival without immunosuppression. METHODS: Tolerance towards human hepatocytes was established by injection of primary human hepatocytes or Huh7 human hepatoma cells into the peritoneal cavities of fetal rats. Corresponding cells were subsequently transplanted into newborn rats via intrasplenic injection within 24h after birth. RESULTS: Mixed lymphocyte assays showed that spleen cells from non-tolerized rats were stimulated to proliferate when exposed to human hepatocytes, while cells from tolerized rats were not. Injections made between 15 d and 17 d of gestation produced optimal tolerization. Transplanted human hepatocytes in rat livers were visualized by immunohistochemical staining of human albumin. By dot blotting of genomic DNA in livers of tolerized rats 16 weeks after hepatocyte transplantation, it was found that approximately 2.5 X 10(5) human hepatocytes survived per rat liver. Human albumin mRNA was detected in rat livers by RT-PCR for 15 wk, and human albumin protein was also detectable in rat serum. CONCLUSION: Tolerization of an immuno-competent rat can permit transplantation, and survival of functional human hepatocytes.

A NEW INTEGRAL TRANSFORM AND ITS APPLICATIONS

In the present paper, the authors introduce a new integral transform which yields a number of potentially useful （known or new） integral transfoms as its special cases. Many fundamental results about this new integral transform, which are established in this paper, in- clude （for example） existence theorem, Parseval-type relationship and inversion formula. The relationship between the new integral transform with the H-function and the H-transform are characterized by means of some integral identities. The introduced transform is also used to find solution to a certain differential equation. Some illustrative examples are also given.

Global Bioethical Prevention of the Collision of Biological and Cultural Evolution on Miserable Human Survival

With the cultural myth that science can only determine the way the world ＂is＂ （facts）, while humanities, social sciences, lawyers, philosophers, and theologians must determine the way the world ＂ought to be＂ （values）, those in position of global-, national-, and local-political power make major decisions of the use （or non-use） of scientific knowledge and technology. As a result, the human being has created a non-scientifically based cultural environment that is affecting his ability to survive. In effect, cultural evolution is occurring more rapidly than biological evolution that can adapt to the changes brought about in the physical and psycho-social environments. In a pluralistic cultural world, where each society has generated a different view of human nature and different ethical values, the use, misuse, or non-use of scientific and technological advances are derived from these unscientific views of human nature. Since all life depends on limiting interacting environmental and ecological factors, it is imperative that scientific information be used to govern how to minimize irreversible effects on life-sustaining ecological factors, but also scientific information bearing on understanding human nature ought to be integrated into a ＂global bioethics＂. While ethical values cannot be directly derived from scientific factors, it is also true that human values or our ＂ought＂ cannot be maintained in ignorance or defiance of the facts or the ＂is＂.

基于广义S变换的多人微多普勒特征分析

微多普勒特征是运动目标的独特特征,可为目标分类识别提供依据。人体行走是典型的非刚体运动,其雷达回波中包含多个频率分量,且分量之间频率重叠严重,因此对其进行微多普勒特征分析难度较大。首先构建人体行走模型及其雷达回波模型,然后以广义S变换为分析工具,对人体主要部位、单人行走和两人行走进行微多普勒特征分析,提出应该以脚部、小腿和躯干部的微多普勒特征作为人体行走识别的主要特征,为后续深入研究人体微多普勒特征奠定了基础。

基于BSWT-DDTFA方法的地球天然脉冲电磁场震前信号时频分析研究

地球天然脉冲电磁场(ENPEMF)信号,可理解为地球天然变化磁场的瞬间扰动,携带了大量有用的地质构造及其动力学信息.研究ENPEMF信号所蕴含的时间-频率联合分布特点,有利于深入了解目标对象的地球物理现象及其地质动力学原理.本文针对ENPEMF信号的非平稳特点,在数据驱动时频分析方法(DDTFA)的基础上提出了基于二值化同步压缩小波变换的改进算法(BSWT-DDTFA).该算法可以实现数据驱动初始相位自动赋值的功能,具有自适应性.实验仿真和实际数据均证明了该改进算法不仅能够得到较为精确的频率曲线和更加清晰的时频分布,而且具有较强的抗噪声能力.以2013年芦山MS7.0地震为例,利用BSWT-DDTFA方法提取ENPEMF信号的时频特性,结果表明ENPEMF信号的时间-频率-幅度分布在震前有明显的异常特征.

试论马克思《1844年经济学哲学手稿》的STS思想

建设有中国特色的STS学派,需要深入研究马克思主义经典著作中的STS思想。《1844年经济学哲学手稿》是马克思批判资本主义早期工业社会的经典著作,包含着丰富的STS思想。在资本主义社会,科学技术不仅是福同时也是祸;在科学技术与社会的互动中必须包含自然;科学技术的进步是人的本质确证;建立起关于人的科学以实现科技与人文的统一。总体而言,马克思是结合人的全面发展来考察科学技术与社会的互动,这对于中国STS学派建设具有重要的指导意义。

Telomere and telomerase in the initial stage of immortalization of esophageal epithelial cell

AIM: To search for the biomarker of cellular immortalization, the telomere length, telomerase activity and its subunits in cultured epithelial cells of human fetal esophagus in the process of immortalization. METHODS: The transgenic cell line of human fetal esophageal epithelium (SHEE) was established with E(6)E(7) genes of human papillomavirus (HPV) type 18 in our laboratory. Morphological phenotype of cultured SHEE cells from the 6th to 30th passages, was examined by phase contrast microscopy, the telomere length was assayed by Southern blot method, and the activity of telomerase was analyzed by telomeric repeat amplification protocol (TRAP). Expressions of subunits of telomerase, hTR and hTERT, were assessed by RT-PCR. DNA content in cell cycle was detected by flow cytometry. The cell apoptosis was examined by electron microscopy (EM) and TUNEL label. RESULTS: SHEE cells from the 6th to 10th passages showed cellular proliferation with a good differentiation. From the 12th to the 16th passages, many senescent and apoptotic cells appeared, and the telomere length sharply shortened from 23kb to 17kb without expression of hTERT and telomerase activity. At the 20th passage, SHEE cells overcame the senescence and apoptosis and restored their proliferative activity with expression of telomerase and hTERT at low levels, but the telomere length shortened continuously to the lowest of 3kb. After the 30th passage cells proliferation was restored by increment of cells at S and G2M phase in the cell cycle and telomerase activity expressed at high levels and with maintenance of telomere length. CONCLUSION: At the early stage of SHEE cells, telomeres are shortened without expression of telomerase and hTERT causing cellular senescence and cell death. From the 20th to the 30th passages, the activation of telomerase and maintenance of telomere length show a progressive process for immortalization of esophageal epithelial cells. The expression of telomerase may constitute a biomarker for detection of immortalization of cells.

Involvement of Rho-associated coiled-coil kinase signaling inhibition in TGF-β1/Smad2,3 signal transduction in vitro

AIM：To research the effect of Y-27632,a selective Rhoassociated coiled-coil kinase（ROCK） inhibitor,on TGF-β1/Smad2,3 signal transduction in ocular Tenon＇s capsule fi broblasts（OTFs）.METHODS：Primary ocular Tenon＇s capsule fibroblasts had been cultured in vitro.The effect of Y27632 on proliferation of OTF stimulated by lysophosphatidic acid（LPA） was evaluated by MTT colorimetric assay so as to sift out the proper concentrations range of Y-27632 for the next experiment.Real time-polymerase chain reactor（RT-PCR） was to analyze the changes of Smad2 and Smad3 genes of cells affected by Y-27632,though unaffected by transforming growth factorbeta1（TGF-β1）.Proteins of Smad2,Smad3,phosphorylated Smad2（Ser245/250/255）,and phosphorylated Smad3（Ser423/425/203） were respectively quantifi ed by Western blot after OTFs were successively incubated by TGF-β1 and Y-27632.Meanwhile,α-smooth muscular actin（α-SMA） protein was also quantified after the small intervening gene fragments of human Smad2 and Smad3 were designed,synthesized,and then transfected to OTFs.RESULTS：Y-27632 signifi cantly inhibited OTFs proliferation stimulated by LPA.Also Y-27632 signifi cantly suppressed the expressions of Smad2 m RNA,Smad2,3 proteins expressions,Smad3 phosphorylation at the carboxylic terminals of Ser423/425/203 which had been radically promoted by TGF-β1.Si RNA-Smad2,3 suppressed α-SMA expressions,but less effectively than Y-27632.CONCLUSION：The inhibition of ROCK signaling may be a potential therapeutic candidate for the treatment of the fi ltration channel fi brosis.

Multiple walking human recognition based on radar micro-Doppler signatures

The recognition of human movements based on radar m-D(micro-Doppler) signatures attracts great interest in the field of radar research on automatic target recognition. Because there are multiple frequency components overlapping seriously in the radar echoes from walking humans, it is a very difficult work to recognize walking humans based on radar echoes. In this paper, a recognition method of walking humans based on radar m-D signatures is proposed. In this method, the m-D spectrum is generated by generalized S transform first,and then the entropy segmentation is used to segment the interesting region from the original spectrum. Next,the m-D features are extracted from the m-D region. Lastly, the support vector machine is used to recognize different walking human targets. The simulation experiments considering two factors of height and velocity are also conducted to test the performance of this proposed method.

迈向投资中心:S公司的人力资源管理变革实践

以S公司的人力资源管理变革为研究对象,通过收集相关人力资源变革资料后发现,按照责任中心划分,S公司的人力资源变革经历了成本中心-利润中心-投资中心3个阶段。S公司在规模逐渐扩大后,通过建立人力资源共享服务中心在内部向其提供服务的业务单位实行虚拟收费,完成其向利润中心型人力资源管理转变;待其成熟后,将其投资设立为人力资源服务全资子公司,对内对外提供人力资源服务,自负盈亏,至此人力资源管理展现迈向投资中心的趋势。

Analytical Algorithm for Systems of Neutral Delay Differential Equations

Delay differential equations (DDEs), as well as neutral delay differential equations (NDDEs), are often used as a fundamental tool to model problems arising from various areas of sciences and engineering. However, NDDEs particularly the systems of these equations are special transcendental in nature;it has therefore, become a challenging task or times almost impossible to obtain a convergent approximate analytical solution of such equation. Therefore, this study introduced an analytical method to obtain solution of linear and nonlinear systems of NDDEs. The proposed technique is a combination of Homotopy analysis method (HAM) and natural transform method, and the He’s polynomial is modified to compute the series of nonlinear terms. The presented technique gives solution in a series form which converges to the exact solution or approximate solution. The convergence analysis and the maximum estimated error of the approach are also given. Some illustrative examples are given, and comparison for the accuracy of the results obtained is made with the existing ones as well as the exact solutions. The results reveal the reliability and efficiency of the method in solving systems of NDDEs and can also be used in various types of linear and nonlinear problems.

Emancipative Development in Contemporary World Politics

In the contemporary world, various political actors, both within and outside of states, have continued to break through subjective and objective constraints to participate more and more widely in the political activities of the world society, which has promoted inclusiveness in the relationship between all actors and fostered reconciliation between man and nature. Historically, the political development of the world has followed two routes: one involves inter-personal relationships, which have evolved gradually through violent and non-violent forms of revolution from one marked by the conflict between the oppressed and the oppressors and between the exploited and the exploiters, to one marked by equality and mutual respect; and the other involves the progress of the forms of production organization and society made possible by the productive forces driving the production relations forward and the change to the economic foundation that forced the superstructure to experience fundamental transformation. The latter is fundamental and recessive, while the former is dominant, which has a direct impact on states and the broader world. In such a progressive evolution, the political transformation of the world has gradually changed from a violent one to a more peaceful one, and the grander trend has changed from having the features of national independence and liberation as well as a people's revolution, to having the features of seeking development in an all-around way and forging a harmonious world free from threat, fear and anxiety.Hereinto, the dominant role of rational human self-restraint is becoming more and more obvious, with which the actors, even those who onceopposed each other, are seeking mutual tolerance, acceptance and cooperation, including human respect for nature and the environment. In essence, this is indicative of the emancipation of human sociality and the reconciliation between man and nature, which is still currently under way.

“One Core,Two Sources”:The Endogenous Logic of China’s Path to Develop Human Rights from the Perspective of“Two Integrations”

Abstract:The development of China’s human rights path is driv-en by both external and internal factors,influenced by general prin-ciples of human rights worldwide while also following China’s own endogenous logic.The concept of the“Two Integrations”reflects the continuous theoretical innovation of the Chinese Communist Party based on China’s national conditions,significantly illustrating the en-dogenous logic of China’s human rights path.Among these,the“basic principles of Marxism”occupy a“core”position within the endoge-nous logic of China’s human rights path,and to some extent,embody an understanding of the inherent laws of human rights.Meanwhile,“China’s specific realities”and“fine traditional Chinese culture”serve as the“living water sources”for the ongoing advancement of China’s human rights.The“Two Integrations”represent an intrinsic requirement of historical materialism and practical materialism.The logical structure of“One Core,Two Sources”explains the endogenous nature of China’s human rights path,offering both an interpretation of the driving forces behind China’s human rights path and a defense of its rationality.

Power and Gaze in Xu Bing’s Dragonfly’s Eye

On August 18,2019,Xu exhibited“The Dragonfly’s Eye”in Today Art Museum.As a respectable writer,Xu drew attention to his elaboration to his illustration of the dragonfly through his own work through incorporating his own artistic interpretation as the new creative mode and idea in art media,further highlighting features of“The Dragonfly’s Eye”.The aesthetic feeling of human nature is emphasized in the creation of Dragonfly’s Eye.Unlike typical contemporary art video works,Dragonfly Eye delivers a whole course of illustration with exceptional production method-through the utilization of existing downloadable videos on the Internet.The project utilizes the romantic story between a young couple to comment on views of life and soul in the contemporary society.Seemingly novelty,the project ultimately centralizes at the idea of the critiquing human nature in the modern ages.

EFFECTS OF ACUPUNCTURE ON IMMUNE RESPONSE RELATED TO OPIOID-LIKE PEPTIDES

Experimental research has recently shown that acupuncture induces the formation of opioid-like peptides (OLPs) in animals. In order to provide further evidence, we tested the beta-endorphin levels and other parameters (VIP, lymphocyte subsets, NK cells and monocyte phagocytosis) in a group of 90 patients suffering from various painful disorders treated with acupuncture. Zusanli (St 36) and Hegu (LI 4) acupoints were selected. A homogeneous group of 30 subjects was used as control. Evaluation of the above parameters was made with 3 series of blood tests before treatment, 30 minutes and 24 hours after acupuncture treatment. In the acupuncture group, the following results were achieved: 1) A considerable increase in beta-endorphin levels remained high even 24 hours after acupuncture treatment. In addition, we demonstrated an inverted correlation between beta-endorphins and VIP; 2) 30 minutes after acupuncture session, 80% of the treated patients showed a significant increase of CD3 and CD4 values and an increase of CD8 24 hours after stimulation; 3) Monocyte phagocytosis was increased in 45% of the treated subjects 30 minutes from starting treatment, and in 100% of them after 24 hours. The percentage of NK cells was also increased in 40% of cases after 30 minutes, and in 50% after 24 hours. However, in the control group, no such significant changes in immune parameters were found.

马克思经济哲学语境中的人化自然理论

马克思文献特别是政治经济学文献中客观存在人化自然理论,论说者的简单化理解使其丰富的内涵被抛入视野黑洞之中。回归文本,原生态检视的结果是如下内容:人化自然是人类的基本问题,意谓人类生存的前提是人化自然;变自然为历史是人类社会历史的起源之处;人化自然理论的逻辑起点是区分人化自然与非人化自然。与传统哲学中的自然理论相比,人化自然理论已消除了传统哲学自然理论中的客观性陷阱,使实践是检验真理唯一标准的要求落到实处。人化自然秉有多重属性,如主体属性、预设属性、法权属性和文明属性等。人化自然与非人化自然的边界处于变动过程之中,前者的边界不断扩张,后者的边界逐步退缩,因而形成人化自然的客观辩证法。人化自然的特质之一是作为主体的人发明并利用中介。人化自然的主要成果是满足人类生存和发展的物质财富,但具体性结果层面显现出多种性质,其中包括对人类有害的性质。人化自然的哲学评价标准是“最无愧于和最适合于”“人类本性”。