Beyond Morality:Han Fei’s Unconventional Insights Into Human Nature

Han Fei presented a thought-provoking perspective on human nature and its implications for governance.Departing from traditional moral doctrines,Han Fei’s“non-moralistic”philosophy posited that human nature is inherently self-interested and driven by personal gain.In this paper,we explore Han Fei’s keen insights into human nature and its practical application in political governance.His emphasis on aligning political strategies with human inclinations,rather than relying solely on moral preaching,highlights the complexity and pragmatism of his approach.However,we also examine the limitations of his philosophy,particularly in disregarding individual differences and idealism.By striking a balance between political expediency and moral considerations,Han Fei’s ideas continue to resonate with contemporary discussions on governance and human behavior.This study calls for a reflective and cautious assessment of the implications of Han Fei’s“non-moralistic”thought in today’s society.

Human Rights Connotations and Its Legal Protection in the Harmonious Coexistence between Humans and Nature

Promoting the unity of human nature and sociality in practice is a fundamental path dependence for achieving people's well-rounded development.Within the context of harmonious coexistence between humans and nature,the practice of the unity of human nature and sociality is allowed to be truly implemented,and people's well-rounded development moves from possibility to reality.Strengthening the protection of human rights for people's well-rounded development in the harmonious coexistence between humans and nature not only requires the expansion of the connotations of environmental rights from“the right to a healthy environment”to“the right to a beautiful environment”,but also necessitates the formation of a collaborative framework between environmental rights and development rights.For legal responses to the expansion of the connotations of environmental rights,it is necessary to implement such expansions in environmental legislation,enhance the underlying principles,and make progress in the development of systematic environmental legislation simultaneously.Regarding the legal promotion of the synergy between environmental rights and development rights,it is essential to follow the guidance of the“Two Mountains Theory,”take the coordinated functions of environmental and traditional legal departments as the basis,and build a legal mechanism for the realization of the value of ecological products and services.

Genetic and epigenetic targets of natural dietary compounds as anti-Alzheimer's agents

Alzheimer’s disease is a progressive neurodegenerative disorder and the most common cause of dementia that principally affects older adults.Pathogenic factors,such as oxidative stress,an increase in acetylcholinesterase activity,mitochondrial dysfunction,genotoxicity,and neuroinflammation are present in this syndrome,which leads to neurodegeneration.Neurodegenerative pathologies such as Alzheimer’s disease are considered late-onset diseases caused by the complex combination of genetic,epigenetic,and environmental factors.There are two main types of Alzheimer’s disease,known as familial Alzheimer’s disease(onset<65 years)and late-onset or sporadic Alzheimer’s disease(onset≥65 years).Patients with familial Alzheimer’s disease inherit the disease due to rare mutations on the amyloid precursor protein(APP),presenilin 1 and 2(PSEN1 and PSEN2)genes in an autosomaldominantly fashion with closely 100%penetrance.In contrast,a different picture seems to emerge for sporadic Alzheimer’s disease,which exhibits numerous non-Mendelian anomalies suggesting an epigenetic component in its etiology.Importantly,the fundamental pathophysiological mechanisms driving Alzheimer’s disease are interfaced with epigenetic dysregulation.However,the dynamic nature of epigenetics seems to open up new avenues and hope in regenerative neurogenesis to improve brain repair in Alzheimer’s disease or following injury or stroke in humans.In recent years,there has been an increase in interest in using natural products for the treatment of neurodegenerative illnesses such as Alzheimer’s disease.Through epigenetic mechanisms,such as DNA methylation,non-coding RNAs,histone modification,and chromatin conformation regulation,natural compounds appear to exert neuroprotective effects.While we do not purport to cover every in this work,we do attempt to illustrate how various phytochemical compounds regulate the epigenetic effects of a few Alzheimer’s disease-related genes.

One-step cell biomanufacturing platform:porous gelatin microcarrier beads promote human embryonic stem cell-derived midbrain dopaminergic progenitor cell differentiation in vitro and survival after transplantation in vivo

Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease.Transplantation of midbrain dopaminergic progenitor cells is a promising treatment for Parkinson’s disease.However,transplanted cells can be injured by mechanical damage during handling and by changes in the transplantation niche.Here,we developed a one-step biomanufacturing platform that uses small-aperture gelatin microcarriers to produce beads carrying midbrain dopaminergic progenitor cells.These beads allow midbrain dopaminergic progenitor cell differentiation and cryopreservation without digestion,effectively maintaining axonal integrity in vitro.Importantly,midbrain dopaminergic progenitor cell bead grafts showed increased survival and only mild immunoreactivity in vivo compared with suspended midbrain dopaminergic progenitor cell grafts.Overall,our findings show that these midbrain dopaminergic progenitor cell beads enhance the effectiveness of neuronal cell transplantation.

Pioneering a New Realm of Human Rights Civilization in the Chinese Path to Modernization——An Overview of the Symposium on“The Chinese Path to Modernization and the Promotion of Free and Comprehensive Human Development”

On October 14,2023,a symposium themed“The Chinese Path to Modernization and the Promotion of Free and Comprehensive Human Development”was held in Changchun,Jilin Province,China.More than fifty experts,scholars,and researchers from national institutions and universities engaged in discussions and exchanges on human rights on the Chinese path to modernization,including the path,practice,knowledge systems,and civilization forms of human rights.This symposium played a significant role in advancing the construction of the disciplinary system,academic system,and discourse system of human rights in China.

Systematic and Theoretical Unfolding of Research on Xi Jinping’s Discourses on Respecting and Protecting Human Rights

Xi Jinping’s discourses on respecting and protect-ing human rights stand as a shining example of the sinicization and modernization of Marxist human rights theory,embodying profound theoretical,political,practical,and cultural logic.Existing research has conducted comprehensive and systematic theoretical analysis and academic extractions on the following contents:the core essence in-herent in these important discourses,including the“theory of human rights concepts,”the“theory of human rights paths,”the“theory of human rights practices,”the“theory of human rights protection,”and the“theory of human rights governance,”along with their profound theoretical significance,practical significance,and global signifi-cance.In the future,researchers should emphasize efforts on studying the original texts and understanding the original principles.While focusing on the precision of concepts,the scientific nature of the prop-ositions,the maturity of theoretical systems,and the rigor of internal logic related to Xi Jinping’s discourses on respecting and protecting human rights,researchers should also pay attention to constructing a discourse system on human rights from the dimensions of discourse power,discourse cluster,and discourse field.Researchers should be adept at drawing innovative insights into human rights theory from China’s vibrant human rights practices and the vast masses of people.This approach will facilitate the systematic unfolding,academic trans-formation,and innovative development of Xi Jinping’s discourses on respecting and protecting human rights.

The “Dead Universe” Theory: Natural Separation of Galaxies Driven by the Remnants of a Supermassive Dead Universe

This article explores the dead universe theory as a novel interpretation for the origin and evolution of the universe, suggesting that our cosmos may have originated from the remnants of a preceding universe. This perspective challenges the conventional Big Bang theory, particularly concerning dark matter, the expansion of the universe, and the interpretation of phenomena such as gravitational waves.

Assessing the dynamics of human activity intensity and its natural and socioeconomic determinants in Qinghai-Tibet Plateau

Investigating the spatiotemporal variation of human activity intensity and its determinants is a crucial basis for further revealing the mechanism of human-environment interaction and optimizing the human development mode.In this study,the human activity intensity on the Qinghai-Tibet Plateau(QTP)from 1990 to 2020 was measured based on the quantitative model of land use data and the actual regional background,and the under-lying natural and socioeconomic determinants were investigated using spatial econometric methods.The results demonstrate that(1)the human activity intensity in QTP has increased by 11.96%,and there are differences in different spatial scales;the areas with high human activity intensity are distributed in the Hehuang Valley where Xining City and its surrounding areas are located,as well as the One-River and Two-River Area where Lhasa City and surrounding areas are located.(2)Human activity intensity has significant positive spatial spillover,suggesting that local changes will cause changes in the same direction in adjacent areas.(3)The human activ-ity intensity in QTP is affected by various determinants.Concerning socioeconomic factors,the economic level has no significant impact on the human activity intensity in QTP,which differs from the general regional law.Both urbanization and traffic conditions have a significant positive effect,and the impact intensity continues to increase.Concerning natural factors,topographic relief has a significant positive effect;the impacts of temper-ature and vegetation coverage have changed from insignificant to a significant positive effect;the impacts of precipitation and river network density have not been verified;there is no linear relationship between altitude and human activity intensity in the entire QTP,while it exists in local regions.Finally,this study proposes three policy implications for the realization of a more harmonious human-environment relationship in QTP.

Human Nature: A Reflection of “The Minister’s Black Veil: A Parable”

According to Hawthorne’s "The Minister’s Black Veil: A Parable", we can know that the author thinks human nature is evil. This paper discusses the following questions: what is human nature? Whether human nature exists? And how to realize human nature?

An Exploration of Human Nature and a Challenge Against Conventional Morality of American South——On the Theme ofThe Adventures of Huckleberry Finn

文章通过对马克.吐温名著《哈克贝利.芬历险记》主题的分析,深刻探讨了马克.吐温对人的本性的探索和对美国南方传统道德的挑战,并进而提出了与现今社会紧密联系的人文关怀问题。

The Evil of Human Nature in Lord of the Flies

William Golding is a very genuinely serious writer because he holds a very strong pessimistic view towards human nature.Lord of the Flies is Golding's first novel.Especially,the novel shows the evil of human nature through little children.In the story,Golding puts those children in an isolated island,which far from the civilization world and without adults'control.The evil nature of human beings explored in the children without the rule of civilization.What's more,Lord of the Flies is a novel which shows the original evil of human's nature.We can learn some evil of human beings from Lord of the Flies as the same as reading Bible.My paper will analyze the evils contained in the novel through three steps.First,analyze main characters and symbol things in the novel.Second,analyze some important things or affaires in the novel.At last,find some more evils of human or society.

Patterns of human-wildlife conflict and compensation practices around Daxueshan Nature Reserve, China

Understanding the spatial patterns of human-wildlife conflict is essential to inform management decisions to encourage coexistence, but it is constrained by the lack of spatially-explicit data. We collected spatially-implicit data of human-wildlife conflicts from 2009-2015 around Daxueshan Nature Reserve, Yunnan, China, and investigated the patterns and drivers of these conflicts. A questionnaire was also designed to capture local resident attitudes toward insurance-based compensation for the losses caused by targeted wildlife. We found that the Asiatic black bear （Ursus thibetanus） was the most conflict-prone animal around the reserve, followed by the rhesus macaque （Macaca mulatta） and Southeast Asian sambar （Cervus equinus）. Conflicts were unevenly distributed among seasons, villages, and communities, with several grids identified as conflict hotspots. Poisson models revealed that human-bear conflicts were negatively related to distance to the reserve and proportion of forest, but positively correlated to the proportion of cropland. Binomial models showed that communities affected by crop depredation were positively correlated with the proportion of cropland and negatively correlated with distance to the reserve, whereas communities affected by livestock depredation were negatively correlated with the proportion of cropland. The insurance-based scheme has compensated over 90% of losses, to the satisfaction of 90.6% of respondents. Our results suggest that human-bear conflict could be potentially reduced by eliminating food crops near the reserve boundary and livestock grazing at conflict hotspots.In addition, the insurance-based scheme could be replicated at a broader scale with improvement in loss assessment.

Marx's Theory of Humanity and Nature

Marx's theory of humanity and nature is an indispensable part of Marx's theory of social development. The history of the development of human society is essentially a natural historical process. Human must start from certain natural premises and start from a combination of certain natural premises and human practices. This is the objective process and inevitable law of the development of human society. Grasping and understanding the scientific connotation of Marx's theory of humanity and nature has very important guiding significance for the development of human society.

A graph theory model using human nature structure

A graph theory model of the human nature structure( GMH) for machine vision and image/graphics processing is described in this paper. Independent from the motion and deformation of contours,the human nature structure( HNS) embodies the most basic movement characteristics of the body. The human body can be divided into basic units like head,torso,and limbs. Using these basic units,a graph theory model for the HNS can be constructed. GMH provides a basic model for human posture processing,and the outline in the perspective projection plane is the body contour of an image. In addition,the GMH can be applied to articulated motion and deformable objects,e. g.,in the design and analysis of body posture,by modifying mapping parameters of the GMH.

Human, Nature, Harmony Self-service Travelling in Stockholm

I decided to visit my friends in Stockholm, Sweden in October. Took an overnight flight to Northern Europe from East Africa, and same as the return journey. It saved me two days of accommodation in this way. I can also go directly to the scenic spots if I am not tired after getting off the plane.

Self-existence,Altru-existence and Human Nature

The question whether human nature is good or evil has been argued about throughout the history.This paper contends that man’s actions are driven by his needs for self-existence and altru-existence.Moral judgment is mostly determined by social norms,and different times may give different judgments to human actions.Whether man is good or evil depends on the actions taken in the situations and from the balance between self-existence and altru-existence in him.The balance point between self-existence and altru-existence may vary from person to person and from culture to culture.Even in the same person,at the different stages of his life or in different situations,the position of the balance point may change accordingly.This paper also applies the idea of balance point to the explanation of the formation of the Chinese national character.

On the Ancient Educational Thought under the Opposite View of Human Nature of the Pre-Qin Scholars--On its Value to Contemporary Higher Education

The pre-qin Scholars’views on human nature could be divided into two types:malleable human nature and immalleable human nature.Based on the theory of the malleability of human nature,Confucianism formed an educational concept aiming at shaping the ideal personality of Confucianism.The theory of immutability of human nature has become the root of the two distinct educational concepts of Taoism,which advocates letting nature take its course,and Taoism,which aims at reforming human behavior.Either idea has its reasonableness.All of these have a very important impact on our higher education today.

The Relationship between Nature and Human Beings in Wide Sargasso Sea

Famous for giving voice to Bertha, the marginalized mad woman in the attic in Jane Eyre, Wide Sargasso Sea is filled with vivid description of nature, which contributes to the successful characterization of main characters and shows the theme of the relationship between nature and human beings. However few attention is paid to that theme. The mythological and archetypal approach is thus adopted to analyze three major characters and fill the gap. Antoinette is viewed as the daughter of nature. Christophine functions as the incarnation of nature. Rochester plays the role of the intruder who does harm to nature. To conclude, Wide Sargasso Sea is not only a criticism of anthropocentrism but also a warning bell to the stereotyped opposition in the western culture. After the successful shaking of the fixed order, Wide Sargasso Sea also drops a hint that there exists the hope to build a new world where human beings and nature, men and women keep a harmonious and balanced relationship.

A Chess Game among Human,Wolves and Nature

Wolf Totem is a famous novel describing wolves as a main part. The article goes deeper into the novel, analyzing the relationship between human beings and nature and the relationship between Mongols and wolves.

A Study of Dialogues about Human Nature in Lord of the Flies

Lord of the Flies is Golding’s most famous and representative novel,which contains many types of dialogues between the characters.Dialogue is a way to communicate and show one’s opinion on a certain topic,which reveals the characters’characteristics,ultimately the human nature.Based on Bakhtin’s three dialogic devices—the syncrisis,the anacrisis and the diatribe,this thesis analyses the dialogues between the characters in Lord of the Flies which reflect the end of innocence and the darkness of human nature.