In the presence or absence of gonadotropins, gonadotropin-releasing hormone (GnRH) and its agonist (GnRHa) exert a paradoxical effect on steroidogenesis in cultured granulosa cells. The peptide is also known to induce...In the presence or absence of gonadotropins, gonadotropin-releasing hormone (GnRH) and its agonist (GnRHa) exert a paradoxical effect on steroidogenesis in cultured granulosa cells. The peptide is also known to induce ovulation in hypophysectomized rats by acting directly at the ovary like the case of hCG. Because tissue展开更多
基金Project supported by the Swedish Medical Research Council and Academia Sinica.
文摘In the presence or absence of gonadotropins, gonadotropin-releasing hormone (GnRH) and its agonist (GnRHa) exert a paradoxical effect on steroidogenesis in cultured granulosa cells. The peptide is also known to induce ovulation in hypophysectomized rats by acting directly at the ovary like the case of hCG. Because tissue