基于OPC UA的分布式数据采集处理系统架构研究

随着物联网与互联网融合的不断深化,感知层与应用层之间的互联互通要求不断提高。针对现有数据采集系统存在的规范性、扩展性和适应性不足的问题,文章提出一套基于对象连接与嵌入过程控制统一架构(object linking and embedding for process control unified architecture,OPC UA)协议的分布式数据采集处理系统架构。对数据采集处理系统各个模块进行功能解耦和架构重组,分别介绍该系统硬件和软件架构;针对发布订阅模式下负载的特异性,提出一种改进的适用于OPC UA分布式订阅的负载均衡算法;最后在某车企实例验证该系统架构。结果表明,基于OPC UA的分布式数据采集处理系统数据采集处理效果良好,证明了该系统架构的可行性及有效性。

基于OPC UA的虚实结合实验设计与实践

OPCUA是一种面向未来的工业通信技术,是实现智能制造的关键技术之一,在工业网络系统中得到越来越广泛的应用。为促进教学资源同步技术发展,以OPCUA技术为出发点,设计了基于OPCUA通信的客户端仿真、系统虚拟仿真、实践操作三个进阶实验项目。项目开发充分利用行业已有客户端测试软件和虚拟仿真软件资源,兼顾线上、线下学习,内容由基础到综合、虚实结合,旨在提升学生新技术应用能力和自主创新能力,更好地服务于智能制造转型升级和发展,为相关专业的实践教学及资源开发提供参考。

基于OPC UA的纤维缠绕机信息模型开发和应用

为实现对复合材料纤维缠绕机生产过程的监测,以缠绕机及其辅助设备为研究对象,针对实际加工设备的多样性造成的加工数据采集的异构性,基于OPC UA建立缠绕机的信息模型架构。根据OPC基金会发布的OPC UA规范和相关的行业标准,建立纤维缠绕机系统的信息模型和实例化。基于开源项目open62541,导入编译后的缠绕机的信息模型代码,自定义开发出符合使用规范的OPC UA服务器,然后利用UA客户端实现对服务器的连接,客户端能够通过服务器查询系统的加工数据,解决加工数据的异构性问题以达到监测缠绕机生产加工过程的目的;最后验证了建立的纤维缠绕机信息模型能够正确导入到开源项目open62541中,实现了加工数据监测。

OPC技术下MATLAB与组态王的水箱研究

当使用上位机软件来处理双容水箱等工业问题时,功能往往难以达到工业自动化的标准。然而,MATLAB优秀的工程计算特性使得它成为理想的选择。使用OPC技术来处理这个问题,并且经过实验,能够实现组态王和MATLAB之间的实时数据交换。

蒲金口服液对宫内感染/炎症致早产脑损伤大鼠脑组织OL、OPC细胞凋亡和Nogo-A、OMgp表达的影响

目的探讨蒲金口服液对宫内感染/炎症致早产脑损伤大鼠神经保护作用的机制。方法将80只胎龄<22 d的早产仔鼠随机分为8组(每组10只):早期药物干预组(蒲金口服液高剂量组、蒲金口服液低剂量组、银杏叶提取物组、模型组)和晚期药物干预组。生后21 d龄进行神经行为学检测,并采用qRT-PCR和Western blot方法检测勿动蛋白-A(Nogo-A)和少突胶质细胞髓磷脂糖蛋白(OMgp)的表达,TUNEL法和A2B5、CNPase双标免疫荧光染色法检测少突胶质细胞(OL)、前体细胞(OPC)凋亡情况。结果LPS组早产仔鼠脑组织Nogo-A和OMgpmRNA和蛋白的表达均明显高于正常对照组(P<0.05),蒲金口服液高剂量、低剂量和银杏叶提取物干预组大鼠的神经行为学评分均优于模型组(P<0.05),且早期干预组高于晚期干预组(P<0.05)。蒲金口服液高剂量、低剂量和银杏叶提取物均能降低早产脑损伤大鼠脑组织Nogo-A、OMgp mRNA和蛋白的表达,减少OL和OPC的凋亡(P<0.05),其中蒲金口服液高剂量早期干预效果更显著(P<0.05)。结论蒲金口服液可以改善早产脑损伤大鼠的神经行为学表现,减少脑组织Nogo-A、OMgp的表达和OL、OPC的凋亡,具有神经保护的作用。

基于OPCE理念的无机化学专创融合教学模式研究

为培养适应社会发展要求的高素质应用型人才,许昌学院化工与材料学院秉承“开放·实践·创新教育”(OPCE,Open,Practical and Creative Education)理念,将无机化学课程知识教育和创新创业教育深度融合,构建了无机化学专创融合教学模式。该课程教学模式的实施培养了学生的创新精神、创业意识和创新创业能力,进而提高了我院应用型人才的培养质量。本文总结了无机化学专创融合教学模式建设的经验,以期为地方高校专创融合课程建设和应用型人才培养提供一定启示。

基于OPC通信协议的采煤机远程监控系统研究

为了解决井下综采工作面自动化设备种类繁多、不同硬件之间通信协议不统一的问题,从软件的角度出发,开发了一种基于OPC通信协议的服务器。该服务器能够集成多种通信协议,如Modbus、Fins等,以实现井下不同设备之间的数据信息交换和协调。通过集成Modbus/TCP通信协议开发了采煤机远程监控系统,并进行了一系列相关测试。实验结果表明,开发的OPC服务器及采煤机远程监控系统可以实现采煤机的实时监控。

OPC技术在RobotStudio与PLC通讯上的应用

针对ABB机器人离线编程调试软件RobotStudio无法与PLC直接通讯的问题,采用RobotStudio与PLC基于OPC技术通讯的方法,即添加OPC客户端功能,将RobotStudio中的焊接门架位置参数与机器人姿态参数通过OPC服务器软件KEPServerEX经以太网传输给PLC,并通过PLC进行焊接门架的参数化控制。经仿真测试,该方案成功解决了RobotStudio与PLC的通讯问题。

Benzydamine hydrochloride ameliorates ethanol-induced inflammation in RAW 264.7 macrophages by stabilizing redox homeostasis

Objective:To evaluate the protective effect of benzydamine hydrochloride against ethanol-induced oxidative stress and inflammation in RAW 264.7 macrophages.Methods:RAW 264.7 macrophages were treated with ethanol(100 mM)and benzydamine hydrochloride(7.5μM).The imflammatory status was confirmed by measuring pro-(TNF-αand IL-6)and anti-inflammatory(IL-10)cytokines through ELISA and RT-PCR assays.Reactive oxygen species generation and mitochondrial membrane potential were investigated to study the protective role of benzydamine hydrochloride against ethanol-induced oxidative stress.Apoptosis detection was also investigated using flow cytometry and acridine orange/ethidium bromide staining.Results:Benzydamine hydrochloride significantly decreased the secretion of TNF-αand IL-6,as well as the generation of reactive oxygen species inside the cells,thereby stabilizing the mitochondrial membrane potential and reducing DNA fragmentation.The ethanol-induced cellular necrosis was also reversed by the administration of benzydamine hydrochloride.Conclusions:Benzydamine hydrochloride ameliorates ethanol-induced cell apoptosis and inflammation in RAW macrophages.

Design and optimization of a greener sinomenine hydrochloride preparation process considering variations among different batches of the medicinal herb

The current methods used to industrially produce sinomenine hydrochloride involve several issues,including high solvent toxicity,long process flow,and low atomic utilization efficiency,and the greenness scores of the processes are below 65 points.To solve these problems,a new process using anisole as the extractant was proposed.Anisole exhibits high selectivity for sinomenine and can be connected to the subsequent water-washing steps.After alkalization of the medicinal material,heating extraction,water washing,and acidification crystallization were carried out.The process was modeled and optimized.The design space was constructed.The recommended operating ranges for the critical process parameters were 3.0–4.0 h for alkalization time,60.0–80.0℃ for extraction temperature,2.0–3.0(volume ratio)for washing solution amount,and 2.0–2.4 mol·L^(-1) for hydrochloric acid concentration.The new process shows good robustness because different batches of medicinal materials did not greatly impact crystal purity or sinomenine transfer rate.The sinomenine transfer rate was about 20%higher than that of industrial processes.The greenness score increased to 90 points since the novel process proposed in this research solves the problems of long process flow,high solvent toxicity,and poor atomic economy,better aligning with the concept of green chemistry.

Degradation of ciprofloxacin hydrochloride in a multiphase mixed system by subaquatic gas-liquid discharge plasma

In recent years, antibiotic pollution has become a serious threat to human health. In this study, a gas-liquid discharge plasma is developed to degrade ciprofloxacin hydrochloride in a multiphase mixed system containing inorganic and organic impurities. The discharge characteristics are analyzed by diagnosing the applied voltage and discharge current waveforms, as well as the optical emission spectra. The work investigates how degradation efficiency is affected by applied voltage, gas flow rate, treatment time, initial concentration as well as the addition of γ-Al_(2)O_(3) pellets and peanut straw. After 70 min, the degradation efficiency of ciprofloxacin hydrochloride in the multiphase mixed system reached 99.6%. Its removal efficiency increases as the initial concentration decreases and the applied voltage increases. Besides, there is still a good degradation efficiency of ciprofloxacin hydrochloride with the addition of peanut straw.The degradation mechanism of ciprofloxacin hydrochloride is investigated through the analysis of degraded intermediates and reactive species.

Method Verification and Validation of Hydralazine Hydrochloride: Spectrophotometric Analysis in Pure and Pharmaceutical Formulations

The new method proposed is based on the formation of hydralazine-Bromophenol blue ion pair simply and without further extraction or heating. The ion pair was prepared in the presence of pH 3 citrate buffer forming a yellow-colored chromogen. A new maximum UV-visible band formed at 416 nm. The color was stable for more than 10 hours and obeyed Beer’s Law over the concentration range of 10 - 50 µg/mL. The calculated molar absorptivity and Sandell’s sensitivity were 1.01 × 104 L∙mol−1∙cm−1 and 0.0514 µg/mL, respectively. The elements of method validation stipulated by The International Conference on Harmonization [Q2 (R1)] were applied for hydralazine hydrochloride assay in pure and pharmaceutical tablet formulation. The average recoveries of the pure solution and the pharmaceutical formulation were 98.94% and 99.50%, respectively. The results were statistically compared by F-test, which indicates that the method can be precise and repeatable for both pure and pharmaceutical solutions. The method was found to be accurate, reproducible, and cost-effective, and validated for the assay of hydralazine in terms of the routine quality control.

Carbon-doped CuFe_(2)O_(4) with C-O-M channels for enhanced Fenton-like degradation of tetracycline hydrochloride: From construction to mechanism

Carbon-doped copper ferrite(C–CuFe_(2)O_(4))was synthesized by a simple two-step hydrothermal method,which showed enhanced tetracycline hydrochloride(TCH)removal efficiency as compared to the pure CuFe_(2)O_(4) in Fenton-like reaction.A removal efficiency of 94%was achieved with 0.2 g L^(-1) catalyst and 20 mmol L^(-1) H_(2)O_(2) within 90 min.We demonstrated that 5%C–CuFe_(2)O_(4) catalyst in the presence of H_(2)O_(2) was significantly efficient for TCH degradation under the near-neutral pH(5–9)without buffer.Multiple techniques,including SEM,TEM,XRD,FTIR,Raman,XPS M€ossbauer and so on,were conducted to investigate the structures,morphologies and electronic properties of as-prepared samples.The introduction of carbon can effectively accelerate electron transfer by cooperating with Cu and Fe to activate H_(2)O_(2) to generate·OH and·O_(2)^(-).Particularly,theoretical calculations display that the p,p,d orbital hybridization of C,O,Cu and Fe can form C–O–Cu and C–O–Fe bonds,and the electrons on carbon can transfer to metal Cu and Fe along the C–O–Fe and C–O–Cu channels,thus forming electron-rich reactive centers around Fe and Cu.This work provides lightful reference for the modification of spinel ferrites in Fenton-like application.

Clinical effect of acupuncture at ghost points combined with fluoxetine hydrochloride on mild-to-moderate depression

BACKGROUND Depression is a common,chronic,and recurrent mood disorder that has become a worldwide health hazard.Fluoxetine hydrochloride,a common treatment method,can inhibit 5-hydroxytryptamine(5-HT)recycling in the presynaptic membrane;however,the efficacy of a single drug is inadequate.At present,mildto-moderate depression can be treated with acupuncture of ghost caves,but the clinical curative effect of combined therapy with fluoxetine hydrochloride has not been sufficiently reported.AIM To evaluate the clinical effect of acupuncture at ghost points combined with fluoxetine hydrochloride in the treatment of mild-to-moderate depression.METHODS This retrospective study included 160 patients with mild-to-moderate depression who were admitted to Shanghai Hospital of Integrated Traditional Chinese and Western Medicine,Affiliated to Shanghai University of Traditional Chinese Medicine,between January 2022 and June 2023.Patients were separated into a single-agent group(fluoxetine hydrochloride treatment,n=80)and a coalition group(fluoxetine hydrochloride treatment combined with acupuncture at ghost points,n=80).Pre-treatment symptoms were recorded,and the clinical curative effect and adverse reactions[Asberg Antidepressant Side Effects Scale(SERS)]were assessed.Depression before and after treatment[Hamilton Depression Scale(HAMD)-24],neurotransmitter levels[5-HT,norepinephrine(NE),dopamine(DA)],oxidative stress indicators[superoxide dismutase(SOD),malondialdehyde(MDA)],and sleep quality[Pittsburgh Sleep Quality Index(PSQI)]were compared.RESULTS The total efficacy rate was 97.50%in the coalition group and 86.25%in the single-agent group(P<0.05).After 2,4,6,and 8 wk of treatment,the HAMD,self-rating depression scale,and SERS scores of the coalition and single-agent groups decreased compared with pre-treatment,and the decrease was more significant in the coalition group(P<0.05).After 8 wk of treatment,the levels of NE,DA,5-HT,and SOD in the coalition and single-agent groups increased,while the levels of MDA decreased;the increases and decrease in the coalition group were more significant(P<0.05).The PSQI scores of the coalition and single-agent groups decreased,and the decrease was more significant in the coalition group(P<0.05).CONCLUSION Acupuncture at ghost points combined with paroxetine tablets can safely improve depressive symptoms and sleep disorders,regulate neurotransmitter levels,and reduce stress responses in patients with mild-to-moderate depression.

基于LabVIEW和OPC的汽车踏板疲劳测试控制系统研究

文章使用LabVIEW进行上位机软件开发,在LabVIEW中采用OPC技术与PLC进行通信实现控制,完成了对汽车踏板疲劳测试装置试验过程的实时监测和控制。实际运行结果证明该系统运行稳定可靠,能够对疲劳测试装置进行控制,实时采集、监测压力数据,导出数据以及系统报警等任务。

ABB工业机器人与LabVIEW基于OPC监控

文章简要介绍了ABB工业机器人与LabVIEW之间通过OPC服务器进行数据监控的解决方案。ABB机器人与LabVIEW通过OPC服务器读取及写入机器人坐标、速度及I/O信号。以此为人机交互提供一个相对简单高效的新思路。

基于OPC UA和RobotStudio的工业机器人工作站集成仿真

针对工业机器人工作站现场集成调试周期长、效率低的问题,基于OPC UA服务器将RobotStudio平台与西门子虚拟PLC控制器建立通信,搭建搬运码垛工作站集成仿真调试环境。在RobotStudio中设计动态工具的Smart组件,离线规划和编写机器人运动轨迹和程序;使用TIA软件编写工作站逻辑程序并下载至虚拟控制器;通过OPC UA建立连接,再利用RobotStudio完成工作站逻辑设计、调试和运动节拍优化。结果表明:该仿真能够有效验证工业机器人运动轨迹和PLC逻辑程序控制的合理性和准确性;调试机器人TCP与外围设备的速度能优化工作站的运动节拍,缩短了工作站现场集成调试周期。为降低工作站集成成本和提高生产效率提供理论依据。

OPC技术在工业LED显示屏中的应用

主要介绍如何利用OPC技术实现把现场信息数据实时显示在工业LED显示屏上,通过编写软件实现WinCC与LED显示屏的信息交换,具有很高的推广价值。

基于OPC UA的双模网关设计

随着工业物联网的快速发展,设备间的互联和数据交换变得越来越重要。OPC UA作为一种开放、跨平台的工业通信协议,已被广泛采用。本文设计了一款基于OPC UA协议的双模网关。OPC UA的SDK采用开源的open62541框架设计,为了实现可靠数据传输以及与其他基于TCP/IP的系统之间的互操作,同时又能提供实时高效的数据传输,本设计采用基于TCP/IP的C/S架构与基于UDP的Pub/Sub架构相结合的方式,实现不同类别的数据分流传输。为了实现用户程序和设备间的解耦,本设计采用JavaScript对象表示法(JSON)格式的配置文件定义设备信息,网关可通过解析该文件实现动态更新节点和设备信息。最后通过实验验证了所设计的双模网关具有较高的可靠性和实时性,适用于工业物联网中设备间数据交换的应用场景。

基于OPC UA的多机系统互联互通技术分析

阐述基于OPC UA的多机系统互联互通技术。介绍OPC UA信息建模规范和机器系统信息模型。在互联互通架构方面,探讨C/S结构、事件、聚合服务器和Web Service等关键组件。提出一个多机系统互联互通验证平台,通过实际应用案例来验证技术的可行性和效果。