In previous studies,researchers have used singing to treat respiratory function in patients with spinal cord injury.However,few studies have examined the way in which vocal training affects respiratory neural plastici...In previous studies,researchers have used singing to treat respiratory function in patients with spinal cord injury.However,few studies have examined the way in which vocal training affects respiratory neural plasticity in patients with spinal cord injury.Vocal respiratory training(VRT)is a type of vocal muscle-related treatment that is often a component of music therapy(MT)and focuses on strengthening respiratory muscles and improving lung function.In this randomized controlled study,we analyzed the therapeutic effects of VRT on respiratory dysfunction at 3 months after cervical spinal cord injury.Of an initial group of 37 patients,26 completed the music therapy intervention,which comprised five 30-minute sessions per week for 12 weeks.The intervention group(n=13)received VRT training delivered by professional certified music therapists.The control group(n=13)received respiratory physical therapy delivered by professional physical therapists.Compared with the control group,we observed a substantial increase in respiratory function in the intervention group after the 12-week intervention.Further,the nerve fiber bundles in the respiratory center in the medulla exhibited a trend towards increased diversification,with an increased number,path length,thickness,and density of nerve fiber bundles.These findings provide strong evidence for the effect of music therapeutic VRT on neural plasticity.This study was approved by the Ethics Committee of China Rehabilitation Research Center(approval No.2020-013-1)on April 1,2020,and was registered with the Chinese Clinical Trial Registry(registration No.Chi CTR2000037871)on September 2,2020.展开更多
High vocal center (HVC) can produce single sound with one or two syllables by the sin-gle-type vocal control pattern in songbirds ruddy bunting (Emberiza rutila). It obviously shows left-side dominance in controlling ...High vocal center (HVC) can produce single sound with one or two syllables by the sin-gle-type vocal control pattern in songbirds ruddy bunting (Emberiza rutila). It obviously shows left-side dominance in controlling double syllables, principal frequency (PF) and increasing sound intensity of the evoked calls. Meanwhile, the complex-type control pattern can produce complex calls with multisyllable, and also shows significant left-side dominance in controlling the number of syllables, tone changing and sound intensity. These indicate that left-side HVC controls higher frequency and complicated sentence structure. The basic vocal center, dorsomedial nucleus of the intercollicular complex (DM), controls the monosyllable sound in songbirds, and shows left-side dominance in controlling both the number of syllable and sound intensity. These results not only provide some direct evidence for left-side dominance in high vocal center, but also indicate that there is some internal connection between the high and basic vocal centers in songbirds.展开更多
基金supported by Scientific Research Project of Establishment of the Winter Olympics Sports Injury Rehabilitation Diagnosis and Treatment System and Green Channel Demonstration of China,No.2018YFF0301104(to JJL)China Rehabilitation Science Institute,No.2020cz-10(to WZW)Scientific Research Foundation of China Rehabilitation Research Center,No.2017zx-32(to XYZ)。
文摘In previous studies,researchers have used singing to treat respiratory function in patients with spinal cord injury.However,few studies have examined the way in which vocal training affects respiratory neural plasticity in patients with spinal cord injury.Vocal respiratory training(VRT)is a type of vocal muscle-related treatment that is often a component of music therapy(MT)and focuses on strengthening respiratory muscles and improving lung function.In this randomized controlled study,we analyzed the therapeutic effects of VRT on respiratory dysfunction at 3 months after cervical spinal cord injury.Of an initial group of 37 patients,26 completed the music therapy intervention,which comprised five 30-minute sessions per week for 12 weeks.The intervention group(n=13)received VRT training delivered by professional certified music therapists.The control group(n=13)received respiratory physical therapy delivered by professional physical therapists.Compared with the control group,we observed a substantial increase in respiratory function in the intervention group after the 12-week intervention.Further,the nerve fiber bundles in the respiratory center in the medulla exhibited a trend towards increased diversification,with an increased number,path length,thickness,and density of nerve fiber bundles.These findings provide strong evidence for the effect of music therapeutic VRT on neural plasticity.This study was approved by the Ethics Committee of China Rehabilitation Research Center(approval No.2020-013-1)on April 1,2020,and was registered with the Chinese Clinical Trial Registry(registration No.Chi CTR2000037871)on September 2,2020.
基金supported by the National Natural Science Foundation of China(Grant No.39570195)Outstanding Youth Foundation of Ministry of Education of China,Science and Technology Research Project of Ministry of Education of China(Grant No.01062)Laboratory of Visual Information Processing Foundation of the Chinese Academy of Sciences.
文摘High vocal center (HVC) can produce single sound with one or two syllables by the sin-gle-type vocal control pattern in songbirds ruddy bunting (Emberiza rutila). It obviously shows left-side dominance in controlling double syllables, principal frequency (PF) and increasing sound intensity of the evoked calls. Meanwhile, the complex-type control pattern can produce complex calls with multisyllable, and also shows significant left-side dominance in controlling the number of syllables, tone changing and sound intensity. These indicate that left-side HVC controls higher frequency and complicated sentence structure. The basic vocal center, dorsomedial nucleus of the intercollicular complex (DM), controls the monosyllable sound in songbirds, and shows left-side dominance in controlling both the number of syllable and sound intensity. These results not only provide some direct evidence for left-side dominance in high vocal center, but also indicate that there is some internal connection between the high and basic vocal centers in songbirds.
