Objective:Through epidemiological investigation,to investigate the etiology and influencing factors of primary gout and hyperuricemia(HUA).Methods:Using case-control methods,designed questionnaires on gout and/or HUA ...Objective:Through epidemiological investigation,to investigate the etiology and influencing factors of primary gout and hyperuricemia(HUA).Methods:Using case-control methods,designed questionnaires on gout and/or HUA related factors(living habits,eating habits and environmental factors,etc).Logistic regression analysis of the survey results was performed with SPSS 19.0 software.Results:(1)Univariate Logistic regression analysis:11 risk factors with statistical significance(P<0.05),often eat sauce food,often eat Fried food,often eat asparagus,often eat nuts,often drink,smoking,drink water<1000ml per day,residential temperature≤17℃in winter,work environment average temperature≤17℃in winter,often exposure to toxic and harmful substances,often use induction cooker or microwave oven(P<0.05),the OR values were 2.063,1.701,3.242,1.560,2.055,1.338,5.700,5.330,2.305,2.821,1.701;3 protective factors,occasionally eat fresh fruit,wake up between 5 and 7 am,use the computer less than 1 hour per day(P<0.05),OR values were 0.723,0.611 and 0.558,respectively.(2)Multivariate Logistic regression analysis was performed for all factors:6 risk factors,The risk factors were often drink,drink water<1000ml per day,residential temperature≤17℃in winter,work environment average temperature≤17℃in winter,use mobile network cellphones and use unicom network cellphones(P<0.05),OR values are 2.008,4.240,4.034,1.889,2.207 and 1.891,respectively;2 protective factors:occasionally eat agaric and use the computer less than 1 hour per day(P<0.05),OR values were 0.551 and 0.536,respectively.Conclusions:Proper improvement of diet structure,adjustment of life and behavior,and avoidance of environmental risk factors can effectively reduce uric acid level,control the incidence of HUA and gout,and improve health level.展开更多
目的研究高尿酸血症对血压水平及高血压患病率的影响。方法对体检检出5 058例高尿酸血症及性别相同、年龄相同或相近的5058例非高尿酸血症进行分析,探讨其对血压水平、高血压患病率的影响及与多种心血管危险因素的关系。结果高尿酸血症...目的研究高尿酸血症对血压水平及高血压患病率的影响。方法对体检检出5 058例高尿酸血症及性别相同、年龄相同或相近的5058例非高尿酸血症进行分析,探讨其对血压水平、高血压患病率的影响及与多种心血管危险因素的关系。结果高尿酸血症组收缩压、舒张压分别较对照组升高4 mm Hg和3 mm Hg,高血压患病率为41.9%（95%C I：40.5%-43.3%）,显著高于对照组31.3%（95%C I：30.0%-32.6%）,差异有统计学意义。高尿酸血症组肥胖、高胆固醇血症及高三酰甘油血症患病率均高于对照组,差异有统计学意义。高尿酸血症、男性、年龄增长、肥胖、糖尿病、高胆固醇血症和高三酰甘油血症是高血压的独立危险因素。结论高尿酸血症与较高的血压水平有关,可能是高血压患病率增加的独立危险因素。展开更多
基金Heilongjiang natural science foundation project(No.H201374)
文摘Objective:Through epidemiological investigation,to investigate the etiology and influencing factors of primary gout and hyperuricemia(HUA).Methods:Using case-control methods,designed questionnaires on gout and/or HUA related factors(living habits,eating habits and environmental factors,etc).Logistic regression analysis of the survey results was performed with SPSS 19.0 software.Results:(1)Univariate Logistic regression analysis:11 risk factors with statistical significance(P<0.05),often eat sauce food,often eat Fried food,often eat asparagus,often eat nuts,often drink,smoking,drink water<1000ml per day,residential temperature≤17℃in winter,work environment average temperature≤17℃in winter,often exposure to toxic and harmful substances,often use induction cooker or microwave oven(P<0.05),the OR values were 2.063,1.701,3.242,1.560,2.055,1.338,5.700,5.330,2.305,2.821,1.701;3 protective factors,occasionally eat fresh fruit,wake up between 5 and 7 am,use the computer less than 1 hour per day(P<0.05),OR values were 0.723,0.611 and 0.558,respectively.(2)Multivariate Logistic regression analysis was performed for all factors:6 risk factors,The risk factors were often drink,drink water<1000ml per day,residential temperature≤17℃in winter,work environment average temperature≤17℃in winter,use mobile network cellphones and use unicom network cellphones(P<0.05),OR values are 2.008,4.240,4.034,1.889,2.207 and 1.891,respectively;2 protective factors:occasionally eat agaric and use the computer less than 1 hour per day(P<0.05),OR values were 0.551 and 0.536,respectively.Conclusions:Proper improvement of diet structure,adjustment of life and behavior,and avoidance of environmental risk factors can effectively reduce uric acid level,control the incidence of HUA and gout,and improve health level.
文摘目的研究高尿酸血症对血压水平及高血压患病率的影响。方法对体检检出5 058例高尿酸血症及性别相同、年龄相同或相近的5058例非高尿酸血症进行分析,探讨其对血压水平、高血压患病率的影响及与多种心血管危险因素的关系。结果高尿酸血症组收缩压、舒张压分别较对照组升高4 mm Hg和3 mm Hg,高血压患病率为41.9%（95%C I：40.5%-43.3%）,显著高于对照组31.3%（95%C I：30.0%-32.6%）,差异有统计学意义。高尿酸血症组肥胖、高胆固醇血症及高三酰甘油血症患病率均高于对照组,差异有统计学意义。高尿酸血症、男性、年龄增长、肥胖、糖尿病、高胆固醇血症和高三酰甘油血症是高血压的独立危险因素。结论高尿酸血症与较高的血压水平有关,可能是高血压患病率增加的独立危险因素。
