Background:Sjögren syndrome(SS)is a long-term autoimmune disease that affects the body’s moisture-producing glands.It can occur independently of other health problems(primary disease)or as a result of another co...Background:Sjögren syndrome(SS)is a long-term autoimmune disease that affects the body’s moisture-producing glands.It can occur independently of other health problems(primary disease)or as a result of another connective tissue disorder(secondary disease).Medication is directed at the person’s symptoms.Recently,it is reported that prescription of Chinese medicine has a great effect on SS and reduce adverse drugs reaction,which can provide a more safer treatment to SS.Case presentation:We here report a 43 year-old Chinese patient with continuous immune thrombocytopenia diagnosed as Sjögren syndrome,who was not response to routine medication such as Methylprednisolone and acyclovir.After that,the patient was treated by prescription of Chinese medicine,and the symptoms were improved apparently.We suppose that prescription of Chinese medicine has an unexpected effect on SS,which can alleviate patient’s symptoms.Conclusion:The clinical efficacy of Sjogren syndrome(SS)is effective in the treatment of prescription of Chinese medicine.It can improve patient’s symptoms and reduce adverse drug reactions.展开更多
Four new phenolic glycosides,including two flavonoid glycosides(1 and 2) and two lignan glycosides(3 and 4),were isolated from the traditional Chinese medicine formula,Baoyuan decoction.Their structures were establish...Four new phenolic glycosides,including two flavonoid glycosides(1 and 2) and two lignan glycosides(3 and 4),were isolated from the traditional Chinese medicine formula,Baoyuan decoction.Their structures were established by detailed analysis of the NMR and HR-ESI-MS spectroscopic data and their absolute configurations were determined by the experimental electronic circular dichroism data as well as chemical methods.Furthermore,the sources of the four new compounds were determined by the UPLC-Qtrap-MS method,which proved that 1 and 2 are originated from Glycyrrhiza uralensis,and 3 and4 are from Cinnamomum cassia.展开更多
基金Traditional Chinese Medicine—Guangxi first-class discipline(No.Gui Jiao Ke Yan[2018]12)Development Program of High-level Talent Team under Qihuang Project of Guangxi University of Chinese Medicine(No.2018005).
文摘Background:Sjögren syndrome(SS)is a long-term autoimmune disease that affects the body’s moisture-producing glands.It can occur independently of other health problems(primary disease)or as a result of another connective tissue disorder(secondary disease).Medication is directed at the person’s symptoms.Recently,it is reported that prescription of Chinese medicine has a great effect on SS and reduce adverse drugs reaction,which can provide a more safer treatment to SS.Case presentation:We here report a 43 year-old Chinese patient with continuous immune thrombocytopenia diagnosed as Sjögren syndrome,who was not response to routine medication such as Methylprednisolone and acyclovir.After that,the patient was treated by prescription of Chinese medicine,and the symptoms were improved apparently.We suppose that prescription of Chinese medicine has an unexpected effect on SS,which can alleviate patient’s symptoms.Conclusion:The clinical efficacy of Sjogren syndrome(SS)is effective in the treatment of prescription of Chinese medicine.It can improve patient’s symptoms and reduce adverse drug reactions.
基金financially supported by the National Natural Sciences Foundation of China(Nos.81222051 and 81530097)the National Key Technology R&D Program“New Drug Innovation”of China(No.2012ZX09301002-002-002)
文摘Four new phenolic glycosides,including two flavonoid glycosides(1 and 2) and two lignan glycosides(3 and 4),were isolated from the traditional Chinese medicine formula,Baoyuan decoction.Their structures were established by detailed analysis of the NMR and HR-ESI-MS spectroscopic data and their absolute configurations were determined by the experimental electronic circular dichroism data as well as chemical methods.Furthermore,the sources of the four new compounds were determined by the UPLC-Qtrap-MS method,which proved that 1 and 2 are originated from Glycyrrhiza uralensis,and 3 and4 are from Cinnamomum cassia.