Re-innervation of sensory and motor neurons on a defined area of the body wall was studied in two species of leeches, Whitmania pigra and Hirudo medicinalis, as a model of segmental animals. Following isolation and ro...Re-innervation of sensory and motor neurons on a defined area of the body wall was studied in two species of leeches, Whitmania pigra and Hirudo medicinalis, as a model of segmental animals. Following isolation and rotation of a tube of body wall, the mechanical sensory and annular erection (AE) motor neurons re-innervated the body wall, at a rate of approximately 3. 8 -8. 4 μm/h. The patterns of re-innerva-tion by pairs of neurons on each side of a ganglion were bilaterally symmetric. The repairs are synchronous for the sensory and motor neurons which are of different functions but in a same ganglion. The gap junctions are widely spread in leech between neurons and glia cells, as well as among the neurons and glia cells themselves. Therefore, it is proposed that the nervous system repair is regulated by a low-resistance pathway. In the xenotransplantation experiments, neurons recognized target tissues before the immuno-recognition and rejection.展开更多
基金Supported by the State Commission of Science and Technology, the National Natural Science Foundation and the State Education Commission of China.
文摘Re-innervation of sensory and motor neurons on a defined area of the body wall was studied in two species of leeches, Whitmania pigra and Hirudo medicinalis, as a model of segmental animals. Following isolation and rotation of a tube of body wall, the mechanical sensory and annular erection (AE) motor neurons re-innervated the body wall, at a rate of approximately 3. 8 -8. 4 μm/h. The patterns of re-innerva-tion by pairs of neurons on each side of a ganglion were bilaterally symmetric. The repairs are synchronous for the sensory and motor neurons which are of different functions but in a same ganglion. The gap junctions are widely spread in leech between neurons and glia cells, as well as among the neurons and glia cells themselves. Therefore, it is proposed that the nervous system repair is regulated by a low-resistance pathway. In the xenotransplantation experiments, neurons recognized target tissues before the immuno-recognition and rejection.
