Vehicle load is among the main factors affecting the deformation of subgrade soil.In this research study,the concept of impact type traffic load is introduced to investigate the effects of vehicle load based on the dy...Vehicle load is among the main factors affecting the deformation of subgrade soil.In this research study,the concept of impact type traffic load is introduced to investigate the effects of vehicle load based on the dynamic stress and displacement time histories acquired from seasonal frozen subgrade soils.Using freezing-thawing and dynamic triaxial tests and considering the amplitude and loading sequence of impact type traffic load,the residual deformation characteristics of subgrade soil under impact type traffic loads and freezing-thawing cycles is studied.It was found that under impact type traffic load,the residual deformation of soils increased sharply as the amplitude of impact type traffic load increased.It was also found that the increase in the amplitude of impact type traffic load led to the increase of residual deformation in a scale of power and exponential function.The amplitudes of impact type traffic load affect the development stress-strain path of the residual strain.After the soil experienced the proper amount of pre-vibration of the light load,residual deformation decreased by 15%.After freezing-thawing,the residual strain of soil increased as the amplitude of the impact type traffic loads increased.Also,when the amplification effect of freezing-thawing on the residual strain was basically stable,the residual deformation increased by about 10%.The peak impact type traffic load had a large effect on soil deformation after the freezing-thawing process,leading to the observation that of the earlier the peaks,the stronger the effect of freezing-thawing.After the soil was subjected to preloading with a small load,the influence of the freezing-thawing cycles gradually stabilized.The results may be useful in preventing and controlling the risk of subgrade soil failure when construction takes place spring thaw periods.展开更多
Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming t...Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming to summarize the results of prior primary research studies on available evidence Community type 2 diabetes structured education (CT2DSHE). Methods: Research question: Type 2 diabetic structured health education within a community how effective is it? Qualitative Systematic review, defined as a way to get reliable and objective picture of current available evidence on the specific topic—(CT2DSHE), (Denscombe, 2021) through reflexivity synthesis of available data as an example. This is valuable in time constraints such as project assignments that must be met within specific time and also to bring together available evidence together [1]. Results: This review has shown that CT2DSHE is effective with seven out of the eleven authors supporting, three authors against and one was neutral, further showed that knowledge and skills acquired can last longer with patient activation improved among T2DM patients ideal for sustaining their self-management of T2DM. Conclusion: This research provides suggestive answers to the research question: “Type 2 diabetic structured health education within a community how effective is it?”, This has demonstrated CT2DSHE effectiveness in knowledge acquisition and improving T2DM awareness among T2DM patients, whilst evidencing long effects beyond the study times of 3 - 9 months period in relation to patient activation. Also Identified diabetes education self-management on newly diagnosed (DESMOND) patient as CT2DSHE program for recommendation. Patient or Public Contribution: This work aspires to contribute to CT2DSHE in these areas;Influencing policy decision-making for community diabetes care within the UK and world at large., Contributing to already vast knowledge on diabetes self-management and reasons why?, Influencing educators on how CT2DSHEP are designed, delivered by putting the patient at the Centre and bringing different perspectives on CT2DSHEP in one place that is serving users time of having to consult several resources especially busy clinicians [2] [3].展开更多
Biological molecules could be used as risk assessment tools for predicting incident Type 2Diabetes Mellitas（T2DM）,such as microR NAs（mi RNAs）.Numerous studies have shown association between miR NA and susceptibili...Biological molecules could be used as risk assessment tools for predicting incident Type 2Diabetes Mellitas（T2DM）,such as microR NAs（mi RNAs）.Numerous studies have shown association between miR NA and susceptibility of T2DM,suggesting that mi RNAs might be common biological factors for T2DM.Interestingly,miR NAs could also serve as novel biomarkers for T2DM epidemiology展开更多
Workplace violence in healthcare settings is increasing worldwide. The risk of verbal and physical aggression towards healthcare workers is especially higher in psychiatry emergency settings. Public safety assistants ...Workplace violence in healthcare settings is increasing worldwide. The risk of verbal and physical aggression towards healthcare workers is especially higher in psychiatry emergency settings. Public safety assistants are integral members of the psychiatry emergency department, who are frequently first responders to those with mental health issues. There is limited evidence discussing the patient-led workplace violence faced by public safety assistants. The purpose of this project is to explore the prevalence of physical and verbal patient-led violence faced by Public Safety Assistants (PSAs) working in psychiatry emergency settings and explore the impact of basic behavioral health education on PSAs in reducing patient-led workplace violence.展开更多
目的分析老年2型糖尿病实施甘精胰岛素+阿卡波糖治疗的效果。方法选取2022年10月—2023年10月枣庄市皮肤病性病防治院收治的92例老年2型糖尿病患者作为研究对象,以奇偶数分组,分为单药组、联合组,各46例,单药组行甘精胰岛素治疗,联合组...目的分析老年2型糖尿病实施甘精胰岛素+阿卡波糖治疗的效果。方法选取2022年10月—2023年10月枣庄市皮肤病性病防治院收治的92例老年2型糖尿病患者作为研究对象,以奇偶数分组,分为单药组、联合组,各46例,单药组行甘精胰岛素治疗,联合组在单一组的基础上增加阿卡波糖治疗,比较两组血糖控制情况、胰岛功能、有效率、不良反应。结果治疗前两组血糖指标对比,差异无统计学意义(P>0.05)。治疗后联合组的血糖指标低于单药组,差异有统计学意义(P<0.05)。治疗前两组胰岛β细胞指数(Homeostasis Model Assessment-β,HOMA-β)、胰岛素抵抗指数(Insulin Resistance Index,HOMA-IR)对比,差异无统计学意义(P均>0.05)。治疗后联合组的HOMA-IR水平低于单药组,HOMA-β水平高于单药组,差异有统计学意义(P均<0.05)。联合组治疗总有效率为97.83%,高于单药组的82.61%,差异有统计学意义(P<0.05)。联合组的不良反应总发生率为8.70%,与单药组的4.35%对比,差异无统计学意义(P>0.05)。结论甘精胰岛素+阿卡波糖的方案控制血糖效果尤为显著,可恢复胰岛素功能,提升有效率,对老年2型糖尿病较适用。展开更多
基金Fundamental Research Foundation for Universities of Heilongjiang Province under Grant No.2018-KYYWF-1651Natural Science Foundation of Heilongjiang Province under Grant Nos.ZD2019E009 and E2016045+1 种基金Scientific Research Fund of Institute of Engineering Mechanics,China Earthquake Administration under Grant Nos.2018D12 and 2019D16National Natural Science Foundation of China under Grant No.51378164。
文摘Vehicle load is among the main factors affecting the deformation of subgrade soil.In this research study,the concept of impact type traffic load is introduced to investigate the effects of vehicle load based on the dynamic stress and displacement time histories acquired from seasonal frozen subgrade soils.Using freezing-thawing and dynamic triaxial tests and considering the amplitude and loading sequence of impact type traffic load,the residual deformation characteristics of subgrade soil under impact type traffic loads and freezing-thawing cycles is studied.It was found that under impact type traffic load,the residual deformation of soils increased sharply as the amplitude of impact type traffic load increased.It was also found that the increase in the amplitude of impact type traffic load led to the increase of residual deformation in a scale of power and exponential function.The amplitudes of impact type traffic load affect the development stress-strain path of the residual strain.After the soil experienced the proper amount of pre-vibration of the light load,residual deformation decreased by 15%.After freezing-thawing,the residual strain of soil increased as the amplitude of the impact type traffic loads increased.Also,when the amplification effect of freezing-thawing on the residual strain was basically stable,the residual deformation increased by about 10%.The peak impact type traffic load had a large effect on soil deformation after the freezing-thawing process,leading to the observation that of the earlier the peaks,the stronger the effect of freezing-thawing.After the soil was subjected to preloading with a small load,the influence of the freezing-thawing cycles gradually stabilized.The results may be useful in preventing and controlling the risk of subgrade soil failure when construction takes place spring thaw periods.
文摘Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming to summarize the results of prior primary research studies on available evidence Community type 2 diabetes structured education (CT2DSHE). Methods: Research question: Type 2 diabetic structured health education within a community how effective is it? Qualitative Systematic review, defined as a way to get reliable and objective picture of current available evidence on the specific topic—(CT2DSHE), (Denscombe, 2021) through reflexivity synthesis of available data as an example. This is valuable in time constraints such as project assignments that must be met within specific time and also to bring together available evidence together [1]. Results: This review has shown that CT2DSHE is effective with seven out of the eleven authors supporting, three authors against and one was neutral, further showed that knowledge and skills acquired can last longer with patient activation improved among T2DM patients ideal for sustaining their self-management of T2DM. Conclusion: This research provides suggestive answers to the research question: “Type 2 diabetic structured health education within a community how effective is it?”, This has demonstrated CT2DSHE effectiveness in knowledge acquisition and improving T2DM awareness among T2DM patients, whilst evidencing long effects beyond the study times of 3 - 9 months period in relation to patient activation. Also Identified diabetes education self-management on newly diagnosed (DESMOND) patient as CT2DSHE program for recommendation. Patient or Public Contribution: This work aspires to contribute to CT2DSHE in these areas;Influencing policy decision-making for community diabetes care within the UK and world at large., Contributing to already vast knowledge on diabetes self-management and reasons why?, Influencing educators on how CT2DSHEP are designed, delivered by putting the patient at the Centre and bringing different perspectives on CT2DSHEP in one place that is serving users time of having to consult several resources especially busy clinicians [2] [3].
基金supported by grants from National Natural Science Foundation of China[81370083,81673247]Australian-China Collaborative Grant[NH&MRC-APP1112767-NSFC 81561128020]
文摘Biological molecules could be used as risk assessment tools for predicting incident Type 2Diabetes Mellitas（T2DM）,such as microR NAs（mi RNAs）.Numerous studies have shown association between miR NA and susceptibility of T2DM,suggesting that mi RNAs might be common biological factors for T2DM.Interestingly,miR NAs could also serve as novel biomarkers for T2DM epidemiology
文摘Workplace violence in healthcare settings is increasing worldwide. The risk of verbal and physical aggression towards healthcare workers is especially higher in psychiatry emergency settings. Public safety assistants are integral members of the psychiatry emergency department, who are frequently first responders to those with mental health issues. There is limited evidence discussing the patient-led workplace violence faced by public safety assistants. The purpose of this project is to explore the prevalence of physical and verbal patient-led violence faced by Public Safety Assistants (PSAs) working in psychiatry emergency settings and explore the impact of basic behavioral health education on PSAs in reducing patient-led workplace violence.
文摘目的分析老年2型糖尿病实施甘精胰岛素+阿卡波糖治疗的效果。方法选取2022年10月—2023年10月枣庄市皮肤病性病防治院收治的92例老年2型糖尿病患者作为研究对象,以奇偶数分组,分为单药组、联合组,各46例,单药组行甘精胰岛素治疗,联合组在单一组的基础上增加阿卡波糖治疗,比较两组血糖控制情况、胰岛功能、有效率、不良反应。结果治疗前两组血糖指标对比,差异无统计学意义(P>0.05)。治疗后联合组的血糖指标低于单药组,差异有统计学意义(P<0.05)。治疗前两组胰岛β细胞指数(Homeostasis Model Assessment-β,HOMA-β)、胰岛素抵抗指数(Insulin Resistance Index,HOMA-IR)对比,差异无统计学意义(P均>0.05)。治疗后联合组的HOMA-IR水平低于单药组,HOMA-β水平高于单药组,差异有统计学意义(P均<0.05)。联合组治疗总有效率为97.83%,高于单药组的82.61%,差异有统计学意义(P<0.05)。联合组的不良反应总发生率为8.70%,与单药组的4.35%对比,差异无统计学意义(P>0.05)。结论甘精胰岛素+阿卡波糖的方案控制血糖效果尤为显著,可恢复胰岛素功能,提升有效率,对老年2型糖尿病较适用。
