Glypican 4 down-regulation in pluripotent stem cells as a potential strategy to improve differentiation and to impair tumorigenicity of cell transplants

Recent advances in stem cell technologies have opened new avenues for the treatment of a number of diseases still lacking effective therapeutic options.Cell transplantation has emerged as among the most promising clinical intervention for disorders such as injuries,diabetes,liver diseases, neurodegeneration and heart failure （Lee et al., 2013; Forbes and Rosenthal, 2014; Tabar and Studer, 2014）.

The Current Situation and Improvement Strategy of Physical Education in Colleges and Universities

At present,physical education is listed as the key teaching.This paper introduces the importance of physical education in Colleges and universities,analyzes the current situation of College Physical Education and explores the improvement strategies of College Physical Education at this stage.

Long term survival improved by optimization of immunosuppression strategy in renal transplant recepients:a single center experience

Objective To investigate influence of immunosuppression strategy optimization on outcomes of renal transplant recipients in the last decades. Methods Data from 404 renal transplant recipients from Jan. 1st,2001 to Dec. 31st,2010 were analyzed retrospectively. The pa-

Current Situation and Improvement Strategies of Teaching Engagement by Teachers in Higher Medical Colleges Under the Background of“New Medical Education”

The“New Medical Education”is a new requirement for the development of medical education in the new era.As a key and core element of the construction of the“New Medical Education,”the engagement in teaching work of university teachers is a key issue that determines the level of teaching development of university teachers and affects the quality of talent cultivation in universities.Using the literature review method,this study analyzed 39 relevant literatures retrieved from China National Knowledge Infrastructure(CNKI)from 1997 to 2023.The concept,connotation,current situation,influencing factors,and improvement strategies of teaching engagement by university teachers were reviewed and summarized.The results showed that the issue of teaching engagement by university teachers has not received high attention in the field of higher education,especially in higher medical education,which has not yet been reported.Although the overall number of literature is not large,some of the conclusions have important implications for the next research on the influencing factors and mechanisms of double-qualified teacher engagement in higher medical colleges.

Recent progress in Ni-rich layered oxides and related cathode materials for Li-ion cells

Undoubtedly,the enormous progress observed in recent years in the Ni-rich layered cathode materials has been crucial in terms of pushing boundaries of the Li-ion battery(LIB)technology.The achieved improvements in the energy density,cyclability,charging speed,reduced costs,as well as safety and stability,already contribute to the wider adoption of LIBs,which extends nowadays beyond mobile electronics,power tools,and electric vehicles,to the new range of applications,including grid storage solutions.With numerous published papers and broad reviews already available on the subject of Ni-rich oxides,this review focuses more on the most recent progress and new ideas presented in the literature references.The covered topics include doping and composition optimization,advanced coating,concentration gradient and single crystal materials,as well as innovations concerning new electrolytes and their modification,with the application of Ni-rich cathodes in solid-state batteries also discussed.Related cathode materials are briefly mentioned,with the high-entropy approach and zero-strain concept presented as well.A critical overview of the still unresolved issues is given,with perspectives on the further directions of studies and the expected gains provided.

Influence of Blended Course Teaching Reform on Student Satisfaction

With the rapid development of information technology in contemporary times,the blended teaching mode that blends online and offline courses has become an international trend in higher education.Taking blended tourism management courses at Chongqing Three Gorges University as an example,we explored the impact of such teaching reform on student satisfaction based on the SERVPERF model.Empirical analysis of 179 valid questionnaires revealed that five elements of the reform,namely,reliability,assurance,valuableness,responsiveness,and empathy,have a significant positive impact on students’learning satisfaction.Specifically,in the context of blended courses,factors such as a stable and reliable teaching environment,comprehensively guaranteed educational conditions,teaching content that highly aligns with students’demands and value expectations,prompt responses to students’needs and feedback,and empathetic consideration of students’perspectives are critical for enhancing student satisfaction.Based on these conclusions,we propose several strategies and methods for improving the effectiveness of blended teaching in the hope of propelling its continuous improvement and optimization,thus further elevating the quality of higher education.

Study on the Improvement Strategies of Physical Environment for Square in Severe Cold Regions' Rural Areas

To improve the comfortable physical environment for square in severe cold regions' rural areas. This paper applies the methods of questionnaires,field testing and statistical analysis to compare and analyze two different square cases of Qingyunpu in Liaoning Province,and conclude the main factors which affect the physical environmental comfort. The improvement strategies for physical environment of rural square are put forward from the aspects of site selection,road position,orientation,landscape design,and ground pavement material selection,aiming to provide the design basis for the physical environment of square in severe cold regions' rural areas.

Genetic Analysis and Improvement Strategies of Protein Content in Rice Seeds

Enhancing the nutritional quality of food crops is a way to improve human nutrition and health. Grain protein content （ GPC ） is an important nutritional quality trait for rice and many other crops. Therefore, it will be very significant to increase GPC and improve rice quality. This paper mainly reviewed the genetic studies GPC in rice, mapping and cloning of QTLs and genes associated with GPC. However, little is known about the molecular mechanism and gene function related to GPC in rice. Thus, here we put forward the genetic strategy by gene pyramiding or molecular marker assisted selection to improve GPC and nutritional quality in rice. This review could provide important information for genetic improvement of grain nutritional quality of rice.

Study on Urban Greenway Improvement Strategies from the Perspective of Landscape Justice

With the consistent development of society,economy and culture,people have had increasing requirements on high-quality public spaces.However,current landscapes have been far away from equal and just for various causes,and to explore the realization of landscape justice has become a key concern in the fi eld of landscape architecture.Greenway as a linear space with bigger scale and strong connectivity in the current green space inventory is easier to update,so it provides a new direction for realizing landscape justice.This paper analyzed the existing greenway policies,design and planning,and problems in using,provided corresponding strategies for improvement,so as to achieve the landscape justice,provide new ideas and instructions for the present greenway construction and maintenance.

A Study on the improvement strategies to Effectiveness of Online Teaching and Learning in EFL Classes in College

English online learning has been common trend in the world, how to teach and learn effectively in EFL classes through online environment is an urgent study. The purpose of the study to analyze the factors of affecting the effectiveness of online teaching and learning in EFL classes in college. We build up a three-dimensional model in the perspective of teacher, learner and technology. And we propose the strategies of improving the effectiveness of online teaching and learning in EFL classes in college in the dimensions of teacher, learner and technology.

Relationship and improvement strategies between drug nanocarrier characteristics and hemocompatibility:What can we learn from the literature

This article discusses the various blood interactions that may occur with various types of nano drug-loading systems. Nanoparticles enter the blood circulation as foreign objects. On the one hand, they may cause a series of inflammatory reactions and immune reactions, resulting in the rapid elimination of immune cells and the reticuloendothelial system, affecting their durability in the blood circulation. On the other hand, the premise of the drug-carrying system to play a therapeutic role depends on whether they cause coagulation and platelet activation, the absence of hemolysis and the elimination of immune cells. For different forms of nano drug-carrying systems, we can find the characteristics, elements and coping strategies of adverse blood reactions that we can find in previous researches. These adverse reactions may include destruction of blood cells, abnormal coagulation system, abnormal effects of plasma proteins, abnormal blood cell behavior, adverse immune and inflammatory reactions, and excessive vascular stimulation. In order to provide help for future research and formulation work on the blood compatibility of nano drug carriers.

Improvement Strategies of Meteorological Movie and Television Services Facing Public Needs

The development course of China＇s meteorological movie and television was analyzed firstly, and then the improvement strategies of meteorological movie and television services facing public needs were put forward based on the statistical results of a meteorological service questionnaire.

The Research Self-Efficacy of Elementary Teachers:Current status,Factors,and Strategies for Improvement

Research self-efficacy is of great significance for teachers to improve their interest and achievements in scientific research.In this study,261 elementary teachers were surveyed through online questionnaires to understand their research self-efficacy.The results showed that most elementary teachers have good research self-efficacy;education background,years of teaching,research environment,and attitude toward research all had influence on the research self-efficacy of elementary teachers.Based on this situation,schools should make efforts,such as improving communication,providing financial support,establishing a scientific research support center,and helping teachers under unfavorable situations.For elementary teachers,they should realize the importance of education research and improve their research literacy。

Research progress on vanadium oxides for potassium-ion batteries

Potassium-ion batteries(PIBs)have been considered as promising candidates in the post-lithium-ion battery era.Till now,a large number of materials have been used as electrode materials for PIBs,among which vanadium oxides exhibit great potentiality.Vanadium oxides can provide multiple electron transfers during electrochemical reactions because vanadium possesses a variety of oxidation states.Meanwhile,their relatively low cost and superior material,structural,and physicochemical properties endow them with strong competitiveness.Although some inspiring research results have been achieved,many issues and challenges remain to be further addressed.Herein,we systematically summarize the research progress of vanadium oxides for PIBs.Then,feasible improvement strategies for the material properties and electrochemical performance are introduced.Finally,the existing challenges and perspectives are discussed with a view to promoting the development of vanadium oxides and accelerating their practical applications.

A Novel Obstacle Avoidance Consensus Control for Multi-AUV Formation System

In this paper, the fixed-time event-triggered obstacle avoidance consensus control for a multi-AUV time-varying formation system in a 3D environment is presented by using an improved artificial potential field and leader-follower strategy(IAPF-LF). Firstly, the proposed fixed-time control can achieve the desired multi-AUV formation within a fixed settling time in any initial system state. Secondly, an event-triggered communication strategy is developed to govern the communication among AUVs, and the communication energy consumption can be decremented. The time-varying formation obstacle avoidance control algorithm based on IAPF-LF is designed to avoid static and dynamic obstacles, the desired formation is maintained in the presence of external disturbances, and there is no Zeno behavior under the fixed-time event-triggered consensus control strategy.The stability of the system is proved by the Lyapunov function and inequality scaling. Finally, simulation examples and water pool experiments are reported to verify the performance of the proposed theoretical algorithms.

LDH-based nanomaterials for photocatalytic applications:A comprehensive review on the role of bi/trivalent cations, anions,morphology, defect engineering, memory effect, and heterojunction formation

Using sunlight to drive chemical reactions via photocatalysis is paramount for a sustainable future.Among several photocatalysts,employing layered double hydrides(LDH) for photocatalytic application is most straightforward and desirable owing to their distinctive two-dimensional(2D) lamellar structure and optical attributes.This article reviews the advancements in bimetallic/trimetallic LDHs and various strategies to achieve high efficiency toward an outstanding performing photocatalyst.Firstly,the tuning of LDH components that control the electro nic and structural properties is explained.The tu ning obtained through the adoption,combination,and incorporation of different cations and anions is also explained.The progress of modification methods,such as the adoption of different morphologies,delamination,and defect engineering towards enhanced photocatalytic activities,is discussed in the mainstream.The band engineering,structural characteristics,and redox tuning are further deliberated to maximize solar energy harvesting for different photocatalytic applications.Finally,the progress obtained in forming hierarchical heterostructures through hybridization with other semiconductors or conducting materials is systematically disclosed to get maximum photocatalytic performance.Moreover,the structural changes during the in-situ synthesis of LDH and the stability of LDH-based photocatalysts are deliberated.The review also summarizes the improvements in LDH properties obtained through modification tactics and discusses the prospects for future energy and environmental applications.

A review on capacity sizing and operation strategy of grid-connected photovoltaic battery systems

Due to the fluctuation and intermittency of distributed PV generation,battery energy storage is required with higher renewable installation towards carbon neutrality.Thus,the photovoltaic battery(PVB)system receives increasing attention.This study provides a critical review on PVB system design optimization,including system component sizing and strategy improvement studies,from mathematical modeling,evaluation system establish-ment to feasibility and optimization studies.Several PVB simulation software packages are compared and eval-uated,and acknowledged system models are presented.The evaluation indicators are summarized from various aspects with cases of various evaluation systems combining different indicators or using the Pareto front for multi-criteria system designing.The PVB system feasibility study is analyzed from system configuration varia-tion,critical technical and economic parameter analyses,rule-based operation strategies to future expectations like large-scale energy storage profitability,grid parity,and energy community trading platform.The targets,methods,tariffand time resolution influences,and PVB system capacity optimization design recommendations are critically discussed.The research directions for system operation development and future expectations are analyzed from system feasibility,flexibility to resilience.The co-planning of PVB system capacity and operation design optimization makes the problem complicated,leading to relatively short time resolution but more flexi-bility to system operation strategy.This study could provide guidance and references to distributed PVB system future design and optimization studies.

Study of the Practice Teaching Reform of Floriculture

This paper analyzes the current situation and problems of the of gardening flowers professional practice teaching, including： rigid and obsolete teaching mode, student learning enthusiasm deficiencies; practice over a single, and the lack of opportunity to practice and platform; lack of software and hardware construction, internship bases imperfect; lack of teachers＇ quality, teaching lack the times. The paper proposes a gardening the flowers professional practice teaching improvement strategies, including： innovative teaching ideas, improvement of education quality; comprehensive local conditions perfect practice, promote the construction and improvement of the practice platform; increase funding, improve the practice teachin~ base; to enhance the training and continuing education to improve practice, the overall quality of the course insla＇uctor.

Comparisons and Improvements of Key Operating Characteristics of Current Source Converter Applied in HVDC System

Because of its controlled power factor and no commutation failure,current source converter(CSC)made up of reverse-blocking IGCTs(RB-IGCTs)offers broad application prospects in the field of HVDC system.Valve voltage and power operating range as the most important operating characteristics should be paid attention to but they are always contradictory.First,the relationship between valve voltage and modulation index is obtained.In particular,valve voltage of converter under the three typical modulation methods is compared,analyzed,and verified.Second,with the help of the independent control strategy and coordinated control strategy of both ends,power operating ranges of the three modulation methods are comprehensively analyzed and compared.Third,in order to solve power coupling at a low active power,the improved coordination control strategy at both ends in this paper is proposed and the relationships among active power,reactive power,DC current and phase angle difference are given in detail.Finally,a 500 kV/3 kA simulation system was built in PSCAD/EMTDC to obtain comparison results of the key operating characteristics of CSC under different modulation methods and the converter can realize unity power operation under random active power after adopting the improved coordinated control strategy,and DC current does not decrease to zero,verifying effectiveness of the coordinated control strategy.

Strategies for Improving Enterprise Standardization Management of Tropical Crop Machinery

There are two categories of tropical crop machinery. One comprises operation machinery that is used for planting, managing and harvesting tropical crops, while the other comprises process machinery for processing tropical crops. Tropical crop machinery is distinguished from other agricultural machinery by the special crops that such machinery cultivates and processes.……