Force and impulse multi-sensor based on flexible gate dielectric field effect transistor

Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other fields.Two-dimensional material-based filed effect transistor(2D-FET)sensors are competitive with nano-level size,lower power consumption,and accurate response.However,few of them has the capability of impulse detection which is a path function,expressing the cumulative effect of the force on the particle over a period of time.Herein we fabricated the flexible polymethyl methacrylate(PMMA)gate dielectric MoS_(2)-FET for force and impulse sensor application.We systematically investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signals(I_(ds))to the detected impulse(I).The applied force was detected and recorded by I_(ds)with a low power consumption of~30 nW.The sensitivity of the device can reach~8000%and the 4×1 sensor array is able to detect and locate the normal force applied on it.Moreover,there was almost no performance loss for the device as left in the air for two months.

Missionary Impulses and American Isolationism and Expansionism

Isolationism and expansionism are two themes of American diplomacy. From the beginning of the state’s history, isolationism and expansionism have manifested themselves as two policy imperatives in American diplomacy. On the surface, isolationism and expansionism represent contradictory attitudes and assumptions about America’s proper relationship with the outside world: isolationism advocates diplomatic and military non-entanglement in world affairs; expansionism urges active involvement in external affairs. But in a deeper sense, both isolationism and expansionism are manifestations of American sense of mission, the belief that the US has a special role to perform for all nations in the world. Isolationism is a passive approach to accomplish that mission: it emphasizes the exemplary nature of their country. Expansionism stresses the need for active involvement to achieve that mission; thus, is an active approach to American mission.

EXISTENCE THEOREMS FOR A SECOND ORDER THREE-POINT BOUNDARY VALUE PROBLEM WITH IMPULSES

In this paper,two existence theorems are given concerning the following 3-point boundary value problem of second order differential systems with impulses[HL(2:1,1Z;2,1Z]x″(t)=f(t,x(t),x′(t)),t∈(0,1),t≠t_k,k=1,2,...,m, Δx|_~t=t_k =I_k(x(t_k)),k=1,2,...,m, Δx′|_~t=t_k =J_k(x(t_k),x′(t_k)),k=1,2,...,m, x(0)=0,x(1)=αx(η).

A method to deliver patterned electrical impulses to Schwann cells cultured on an artificial axon

Information from the brain travels back and forth along peripheral nerves in the form of electrical impulses generated by neurons and these impulses have repetitive patterns. Schwann cells in peripheral nerves receive molecular signals from axons to coordinate the process of myelination. There is evidence, however,that non-molecular signals play an important role in myelination in the form of patterned electrical impulses generated by neuronal activity. The role of patterned electrical impulses has been investigated in the literature using co-cultures of neurons and myelinating cells. The co-culturing method, however, prevents the uncoupling of the direct effect of patterned electrical impulses on myelinating cells from the indirect effect mediated by neurons. To uncouple these effects and focus on the direct response of Schwann cells,we developed an in vitro model where an electroconductive carbon fiber acts as an artificial axon. The fiber provides only the biophysical characteristics of an axon but does not contribute any molecular signaling.In our "suspended wire model", the carbon fiber is suspended in a liquid media supported by a 3D printed scaffold. Patterned electrical impulses are generated by an Arduino 101 microcontroller. In this study, we describe the technology needed to set-up and eventually replicate this model. We also report on our initial in vitro tests where we were able to document the adherence and ensheath of human Schwann cells to the carbon fiber in the presence of patterned electrical impulses(hSCs were purchased from ScienCell Research Laboratories, Carlsbad, CA, USA; ScienCell fulfills the ethic requirements, including donor's consent). This technology will likely make feasible to investigate the response of Schwann cells to patterned electrical impulses in the future.

Interpreting Dose-Response Relation for Exposure to Multiple Sound Impulses in the Framework of Immunity

Hearing loss is a common military health problem and it is closely related to exposures to impulse noises from blast explosions and weapon firings. In a study based on test data of chinchillas and scaled to humans (Military Medicine, 181: 59-69), an empirical injury model was constructed for exposure to multiple sound impulses of equal intensity. Building upon the empirical injury model, we conduct a mathematical study of the hearing loss injury caused by multiple impulses of non-uniform intensities. We adopt the theoretical framework of viewing individual sound exposures as separate injury causing events, and in that framework, we examine synergy for causing injury (fatigue) or negative synergy (immunity) or independence among a sequence of doses. Starting with the empirical logistic dose-response relation and the empirical dose combination rule, we show that for causing injury, a sequence of sound exposure events are not independent of each other. The phenomenological effect of a preceding event on the subsequent event is always immunity. We extend the empirical dose combination rule, which is applicable only in the case of homogeneous impulses of equal intensity, to accommodate the general case of multiple heterogeneous sound exposures with non-uniform intensities. In addition to studying and extending the empirical dose combination rule, we also explore the dose combination rule for the hypothetical case of independent events, and compare it with the empirical one. We measure the effect of immunity quantitatively using the immunity factor defined as the percentage of decrease in injury probability attributed to the sound exposure in the preceding event. Our main findings on the immunity factor are: 1) the immunity factor is primarily a function of the difference in SELA (A- weighted sound exposure level) between the two sound exposure events;it is virtually independent of the magnitude of the two SELA values as long as the difference is fixed;2) the immunity factor increases monotonically from 0 to 100% as the first dose is varied from being significantly below the second dose, to being moderately above the second dose. The extended dose-response formulation developed in this study provides a theoretical framework for assessing the injury risk in realistic situations.

A Boundary Value Problem for Second Order Functional Differential Equations with Impulses

Aim To investigate the boundary value problem for second order functional differentiai equations with impulses. Methods The fixed point principle was used to establish our results. Results and Conclusion The results of the esistence, the uniqueness and the continuous dependence on aprameter of soiutions of the boundary value problems for second order functional differential equations with impulses are obtained.

Periodic Boundary Value Problem for Functional Differential Equations with Impulses

Aim To investigate the periodic boundary value problem for functional differential equations with impulses. Methods The method of upper and lower solutions and the monotone iterative technique were used to establish our results. Results and Conclusion The results of the existence of maximal and minimal solutions of the periodic boundary value problem for functional differential equations with impulses are obtained.

Global exponential stability of Cohen-Grossberg neural networks with time-varying delays and impulses

In this paper, the Cohen-Grossberg neural networks with time-varying delays and impulses are considered. New sufficient conditions for the existence and global exponential stability of a unique equilibrium point are established by using the fixed point theorem and Lyapunov functional. An example is given to demonstrate the effectiveness of our results.

Risk of Hearing Loss Caused by Multiple Acoustic Impulses in the Framework of Biovariability

We consider the hearing loss injury among subjects in a crowd with a wide spectrum of individual intrinsic injury probabilities due to biovariability. For multiple acoustic impulses, the observed injury risk of a crowd vs the effective combined dose follows the logistic dose-response relation. The injury risk of a crowd is the average fraction of injured. The injury risk was measured in experiments as follows: each subject is individually exposed to a sequence of acoustic impulses of a given intensity and the injury is recorded;results of multiple individual subjects were assembled into data sets to mimic the response of a crowd. The effective combined dose was adjusted by varying the number of impulses in the sequence. The most prominent feature observed in experiments is that the injury risk of the crowd caused by multiple impulses is significantly less than the value predicted based on assumption that all impulses act independently in causing injury and all subjects in the crowd are statistically identical. Previously, in the case where all subjects are statistically identical (i.e., no biovariability), we interpreted the observed injury risk caused by multiple impulses in terms of the immunity effects of preceding impulses on subsequent impulses. In this study, we focus on the case where all sound exposure events act independently in causing injury regardless of whether one is preceded by another (i.e., no immunity effect). Instead, we explore the possibility of interpreting the observed logistic dose-response relation in the framework of biovariability of the crowd. Here biovariability means that subjects in the crowd have their own individual injury probabilities. That is, some subjects are biologically less or more susceptible to hearing loss injury than others. We derive analytically the distribution of individual injury probability that produces the observed logistic dose-response relation. For several parameter values, we prove that the derived distribution is mathematically a proper density function. We further study the asymptotic approximations for the density function and discuss their significance in practical numerical computation with finite precision arithmetic. Our mathematical analysis implies that the observed logistic dose-response relation can be theoretically explained in the framework of biovariability in the absence of immunity effect.

IMPULSIVE DIFFERENTIAL EQUATIONS WITH GAMMA DISTRIBUTED MOMENTS OF IMPULSES AND P-MOMENT EXPONENTIAL STABILITY

Differential tigated. We study the properties of solutions sufficient conditions for equations with impulses at random moments are set up and invescase of Gamma distributed random moments of impulses. Several are studied based on properties of Gammma distributions. Some p-moment exponential stability of the solutions are given.

A Sandwich Control System with Dual Stochastic Impulses

Dear editor,Along with the progress of science and technology and the development of social civilization,control system brings an increasingly significant function in daily life.The application field of control system is very wide,for instance,in mobile technology[1],artificial earth satellite[2],pest control[3],etc.Ribeiro[4]first put forward the concept of random pulse in 1967.At present,impulsive control is used in networked control[5],secure communication[6],etc.In the 21st century,the impulsive control has been used in synchronization of coupled system,intelligent fault identification,image encryption.

Positive periodic solution for a nonautonomous periodic model of population with time delays and impulses

In this paper, a nonautonomous periodic model of population with time delays and impulses, which arises in order to describe the control of a single population of cells, is studied. By the coincidence degree theory we obtain the conditions for the existence of periodic solution of this system.

Preliminary results of acoustic radiation force impulses (ARFI) ultrasound imaging of solid suspicious breast lesions

Objective： The aim of our study was to make the qualitative and quantitative analysis to breast lesions using acoustic radiation force impulses （ARFI）, and assess the diagnostic value of ARFI for differentiation between benign and malignant solid breast masses, meanwhile evaluate the influences of ARFI with breast imaging reporting and data system （BI-RADS） of suspicious masses. Methods： Seventy-five women with 86 breast lesions underwent conventional breast ultra- sound examination. Then B-mode BI-RADS features and assessments were recorded and standard breast US supplemented by ARFI elastographic examination were repeated. The data were recorded and analyzed as following： area ratio of breast lesion, the shear-wave velocity, the ratio of the shear-wave velocity between lesions and surrounding normal tissues, and according to the elastographic data reconsidered the BI-RADS category, all the results have been correlated with pathological results and make statistical evaluations of ARFI for differentiation between benign and malignant solid breast masses. Meantime our study has correlated the adjusted BI-RADS category of suspicious breast lesions with the pathological results and made assessment. Results： Thirty-eight patients were malignant breast carcinoma （31 invasive ductal carcinoma, 5 intraductal carcinoma in situ, 2 medullary carcinoma, 2 invasive Iobular carcinoma）, 48 patients were benign breast lesions （23 fibroadenoma, 12 benign nodular hyperplasia, 5 phyllodes tumor, 6 adenosis, 2 intraductal papilloma）. Underwent conventional breast ultrasound exam, 42 cases were BI-RADS category 3, 23 cases were BI-RADS category 4. When adding elastographic data, 46 cases were BI-RADS category 3 and 20 cases were BI-RADS category 4. Compared with pathological results showed for both the specificity of BIRADS features and the area under ROC curve has risen. Virtual touch tissue imaging （VTI） and virtual touch tissue quantification （VTQ） data showed the area ratio （AR） between elastographic lesions area and B-mode lesions area, SWV （maximal shear-wave velocity of lesions）, R-SWV （shear-wave velocity ratio between lesions and surrounding normal tissues） in benign breast lesions were lower than those in malignant lesions which has statistical significance and the cut-off point were 1.1,4.65 m/s, 5.18 respectively. Conclusion： The ARFI elastography can provide the reliable qualitative and quantitative analysis about hardness of breast lesions, supply the new BI-RADS category features to suspicious breast masses and serve as an effective diagnostic tool for differentiation between benign and malignant solid masses.

Variational Methods to Nonlinear Differential Equations with Non-instantaneous Impulses

The author aimed to investigate the solvability for nonlinear differential equations with not instantaneous impulses.Variational approach was adopted to obtain the existence of weak solutions as critical points. The findings of this study may serve as a reference for multiplicity of impulsive problems.

Influence of an irradiation of a liquid phase by nanosecond electromagnetic impulses (NEMI) on properties of metals and alloys

The results of research on influence of an irradiation of a liquid phase by nanosecond electromagnetic impulses(NEMI) on processes of crystallization and structurization,physicomechanical and operational properties of copper,aluminium and alloys on their basis(bronze and silumin) were presented.

EXISTENCE,UNIQUENESS AND APPROXIMATION OF THE SOLUTION OF AN ODE WITH (INFINITELY MANY) STATE-DEPENDENT IMPULSES VIA FIXED MESH GALERKIN FORMULATION

A fixed mesh variational formulation is used to establish existence and uniqueness of the solution of ordinary differential equations with (in finitely many) state-dependent in pulses on the right-hand side. This approach gives a natural numerical scheme to approximate the solution.The convergence of the approximation is proved and its asymptatic order obtained.

Some Notes of p-Moment Boundedness of Nonlinear Differential Equation with Pandom Impulses

A model of nonlinear differential systems with impulsive effect on random moments is considered. The extensions of qualitative analysis of the model is mainly focused on and three modified sufficient conditions are presented about p-moment boundedness in the process by Liapunov method with nonlinear item dependent on the impulsive effects, which may gain wider use in industrial engineering, physics, etc. At last, an example is given to show an theoretical application of the obtained results.

Partial extinction, permanence and global attractivity innonautonomous n-species Lotka-Volterra competitivesystems with impulses

In this paper, the qualitative properties of general nonautonomous Lotka-Volterran-species competitive systems with impulsive e？ects are studied. Some new criteria on thepermanence, extinction and global attractivity of partial species are established by used themethods of inequalities estimate and Liapunov functions. As applications, nonautonomous twospecies Lotka-Volterra systems with impulses are discussed.

Periodic Solution for a Stochastic Predator-Prey Model with Impulses and Holling-II Functional Response

Considering the mutual interference between species, a stochastic predator-prey model with impulses and Holling-II functional response is proposed in this paper. Firstly, by constructing an equivalent system without impulses, the existence of a globally unique positive solution is proved. Secondly, in cases of the mutual coefficient m = 1 and 0 m < 1, by constructing suitable Lyapunov functional, the existence of T-periodic solution is investigated under some certain conditions. Finally, numerical simulation is introduced to verify our main results.

Financial Decision-Making： The Roles of Intuition, Heuristics, and Impulses

This paper will add to an evolving new paradigm for financial decision-making by exploring the important roles that intuition, heuristics, and impulses play as a bridge between how the conscious and unconscious can work together more effectively in making better decisions. Historically, the roles of financial/accounting theory and cognitive psychology have been extensively studied and documented in attempting to explain individual financial decision-making. More recently, neuroscience has made substantial contributions to learning how prospective financial decisions and outcomes affect brain activity and observed decision-making behavior. The evidence from neuroscience indicates that up to 90% of our decisions are initiated at the unconscious level, which is only beginning to be investigated in a systematic manner. Integrating these findings from multiple disciplines, including recent contributions from neuroscience, has many implications, not only with respect to personal and corporate financial decisions and how markets work, but also as an essential component in the tool box of the general decision maker.