Study on the Influencing Factors and Mechanisms of the Evolution of the Architectural Characteristics of Guangfu Ancestral Halls in the Ming and Qing Dynasties

This paper discusses ancestral hall architecture within the context of the Cantonese folk lineage in the Pearl River Delta.Using a typological research approach and chronological analysis,various factors that have influenced the evolution of ancestral hall architecture are analyzed.The study specifically investigates the features of ancestral halls during the Ming and Qing dynasties.Three periods of ancient China are analyzed:The transition from Ming to Qing,the mid-Qing dynasty,and the late Qing dynasty.The variables of each period and how they influence the evolution of architectural typological features are identified.Based on our analysis,architectural features are related to economic and social factors,materials available,and craftsmanship of the construction workers.

Unraveling the Fundamental Mechanism of Interface Conductive Network Influence on the Fast‑Charging Performance of SiO‑Based Anode for Lithium‑Ion Batteries

Progress in the fast charging of high-capacity silicon monoxide(SiO)-based anode is currently hindered by insufficient conductivity and notable volume expansion.The construction of an interface conductive network effectively addresses the aforementioned problems;however,the impact of its quality on lithium-ion transfer and structure durability is yet to be explored.Herein,the influence of an interface conductive network on ionic transport and mechanical stability under fast charging is explored for the first time.2D modeling simulation and Cryo-transmission electron microscopy precisely reveal the mitigation of interface polarization owing to a higher fraction of conductive inorganic species formation in bilayer solid electrolyte interphase is mainly responsible for a linear decrease in ionic diffusion energy barrier.Furthermore,atomic force microscopy and Raman shift exhibit substantial stress dissipation generated by a complete conductive network,which is critical to the linear reduction of electrode residual stress.This study provides insights into the rational design of optimized interface SiO-based anodes with reinforced fast-charging performance.

Mesoscale Mechanical Properties and Influencing Factors of Concrete under Uniaxial Tension

Monte Carlo simulations were carried out to generate a mesoscale model of concrete with randomly packed aggregates with different shapes and sizes.The mechanical properties of concrete specimens under uniaxial tensile loads were studied using statistical results.The results indicated that the entire process of damage and failure of specimens exhibited mainly two failure types:fracture patternsⅠandⅡ.Furthermore,the influences of the aggregate content ratio,aggregate shape,aggregate size,interfacial transition zone(ITZ)strength,and porosity ratio on the concrete specimens were analyzed.The numerical simulation results showed that the elastic modulus of the concrete specimens increased approximately linearly with the aggregate volume ratio but decreased linearly with the porosity and was not affected by the ITZ strength.The tensile strength decreased with the increases in the aggregate content and porosity of the sample,but increased linearly with the ITZ strength.In addition,the aggregate shape led to a difference in the tensile strength of the concrete.

Failure mechanism and influencing factors of cement sheath integrity under alternating pressure

The failure of cement sheath integrity can be easily caused by alternating pressure during large-scale multistage hydraulic fracturing in shale-gas well.An elastic-plastic mechanical model of casing-cement sheath-formation(CSF)system under alternating pressure is established based on the Mohr-Coulomb criterion and thick-walled cylinder theory,and it has been solved by MATLAB programming combining global optimization algorithm with Global Search.The failure mechanism of cement sheath integrity is investigated,by which it can be seen that the formation of interface debonding is mainly related to the plastic strain accumulation,and there is a risk of interface debonding under alternating pressure,once the cement sheath enters plasticity whether in shallow or deep well sections.The matching relationship between the mechanical parameters(elastic modulus and Poisson's ratio)of cement sheath and its integrity failure under alternating pressure in whole well sections is studied,by which it has been found there is a“critical range”in the Poisson's ratio of cement sheath.When the Poisson's ratio is below the“critical range”,there is a positive correlation between the yield internal pressure of cement sheath(SYP)and its elastic modulus.However,when the Poisson's ratio is above the“critical range”,there is a negative correlation.The elastic modulus of cement sheath is closely related to its Poisson's ratio,and restricts each other.Scientific and reasonable matching between mechanical parameters of cement sheath and CSF system under different working conditions can not only reduce the cost,but also protect the cement sheath integrity.

Review of emulsified asphalt modification mechanisms and performance influencing factors

In recent years,with the improvement of the requirements of road performance,modified emulsified asphalts with better performance has gradually replaced the emulsified asphalt and become the primary material for road maintenance.This paper introduces the modified emulsified asphalt materials commonly used in pavement maintenance projects,definitions and modified mechanisms of polymerized styrene butadiene rubber(SBR)modified emulsified asphalt,styrene butadiene styrene block polymer(SBS)modified emulsified asphalt and waterborne epoxy resin(WER)modified emulsified asphalt are summarized.The analysis focused on comparing the effects of modifiers,preparation process,auxiliary additives,and other factors on the performance of modified emulsified asphalt.In this paper,it is considered that the greatest impact on the performance of emulsified asphalt is the modifier,emulsifier mainly affects the speed of breaking the emulsion,stabilizers on the basic performance of emulsified asphalt evaporative residue is small;and when the modifier is distributed in the asphalt in a network,the dosage at this time is the recommended optimum dosage.Finally,this study recommends that in the future,the polymer-asphalt compatibility can be improved through composite modification,chemical grafting and other methods to continue to develop broader applicability and better performance of modified emulsified asphalt.

Withdrawal Intention of Farmers from Vacant Rural Homesteads and Its Influencing Mechanism in Northeast China: A Case Study of Jilin Province

The effective use of land in Northeast China is of great significance for ensuring national food security and regional rural revitalization.In this study,based on the survey data collected from Jilin Province,Northeast China,we analyzed the vacancy rates of rural homesteads in suburban,outer suburban,and remote villages,as well as the withdrawal intention of rural-settled farmers,urbansettled farmers,and farmers with urban and rural dual residency from vacant homesteads.From the perspective of farmers’perceptions,this study constructed a theoretical framework of the influence mechanism of their withdrawal intention and analyzed such mechanism by constructing a structural equation model.The results indicated that:1)rural homestead vacancy rates increased with distance from the village to the city.2)rural-settled farmers showed a low withdrawal intention for vacant rural homesteads,followed by urban and rural dual-residence farmers,and urban-settled farmers showed the highest withdrawal intention.3)the relative importance of the factors influencing withdrawal intention is in the following order:policy awareness>interest perception>living environment perception>family characteristics.Finally,this study discussed the reformation of the homestead system and rural homestead transition in Northeast China,which can provide policy support to increase the potential of cultivated land and promote sustainable rural development and urban-rural coordination.

Influencing mechanism and hydrogeological implications of water level fluctuation of lakes in the northern Qaidam Basin,Qinghai-Tibet Plateau

The Qaidam Basin(QB)is a concentrated distribution area and chemical industrial bases of salt lakes in China.Lakes in the QB have been expanding during the past 20 years.Rapid lake expansion resulted in some considerable scientific issues on the protection of salt lake resources and infrastructure,and monitoring of hydrological processes at the lake-basin scale.Although the spatial-temporal trends of lake changes on the Qinghai-Tibet Plateau(QTP)have been well documented,the underlying influencing mechanism and hydrogeological implications of rapid lake changes in the QB are not well understood.Three lakes in the northern QB were selected to investigate lake water level fluctuations on different time scales based on extensive in-situ monitoring and satellite observations.The influencing mechanism and hydrogeological implications of rapid changes of terminal lakes were discussed in combination with the reported increasing precipitation rate and mass balance of glaciers in the northern QTP.Results reveal the following:(1)the fluctuation pattern of Sugan Lake was asynchronous and out of phase with that of Xiao Qaidam and Toson lakes during the monitoring period;(2)Sugan Lake water rose gradually,and the rise interval was from late April to early July.In contrast,Xiao Qaidam and Toson lakes took on a rapid and steep rise,and the rise intervalwas from late July to September;(3)the influencing mechanisms for rapid lake fluctuations are controlled by different factors:glacier and snow melting with increasing temperature for Sugan Lake and increasing precipitation for Xiao Qaidam and Toson lakes;(4)in accordance with different intervals and influencing mechanisms of rapid lake expansions in the QB,hydrological risk precaution of lakes and corresponding river catchments was conducted in different parts of the basin.This study provided an important scientific basis for assessing the hydrological process and hydrological risk precaution,and protection of salt lake resources along with rapid lake expansions in the arid area.

Study on Influencing Factors and Mechanism of Scientific and Technological Innovation Talents Gathering in Zhejiang Province

This paper systematically studies the influencing factors and mechanism of the agglomeration of scientific and technological innovation talents in Zhejiang Province. The findings are as follows: Firstly, environmental factors such as marketization level, financial development, opening to the outside world, infrastructure construction, medical resources, educational resources, cultural resources and policy support have a positive impact on the agglomeration of scientific and technological talents in Zhejiang Province;Secondly, in the transmission mechanism of the influence of various environmental factors on the concentration of scientific and technological talents in Zhejiang, economic development plays an intermediary role, and the effect is obvious. Various environmental factors indirectly affect the concentration of scientific and technological talents in Zhejiang through economic development. Finally, although both the level and quality of economic development have significant effect on the total concentration of scientific and technological talents in Zhejiang, the mediating effect of economic development level is more significant. These studies are for Zhejiang Province. It provides a theoretical basis for cultivating high-end talents and realizing the agglomeration of scientific and technological innovation talents.

Regeneration of the heart:f rom molecular mechanisms to clinical therapeutics

Heart injury such as myocardial infarction leads to cardiomyocyte loss,fibrotic tissue deposition,and scar formation.These changes reduce cardiac contractility,resulting in heart failure,which causes a huge public health burden.Military personnel,compared with civilians,is exposed to more stress,a risk factor for heart diseases,making cardiovascular health management and treatment innovation an important topic for military medicine.So far,medical intervention can slow down cardiovascular disease progression,but not yet induce heart regeneration.In the past decades,studies have focused on mechanisms underlying the regenerative capability of the heart and applicable approaches to reverse heart injury.Insights have emerged from studies in animal models and early clinical trials.Clinical interventions show the potential to reduce scar formation and enhance cardiomyocyte proliferation that counteracts the pathogenesis of heart disease.In this review,we discuss the signaling events controlling the regeneration of heart tissue and summarize current therapeutic approaches to promote heart regeneration after injury.

The underlying mechanism of variety–water–nitrogen–stubble damage interactions on yield formation in ratoon rice with low stubble height under mechanized harvesting

Agronomic measures are the key to promote the sustainable development of ratoon rice by reducing the damage from mechanical crushing to the residual stubble of the main crop, thereby mitigating the impact on axillary bud sprouting and yield formation in ratoon rice. This study used widely recommended conventional rice Jiafuzhan and hybrid rice Yongyou 2640 as the test materials to conduct a four-factor block design field experiment in a greenhouse of the experimental farm of Fujian Agricultural and Forestry University, China from 2018 to 2019.The treatments included fertilization and no fertilization, alternate wetting and drying irrigation and continuous water flooding irrigation, and plots with and without artificial crushing damage on the rice stubble. At the same time, a 13C stable isotope in-situ detection technology was used to fertilize the pot experiment. The results showed significant interactions among varieties, water management, nitrogen application and stubble status.Relative to the long-term water flooding treatment, the treatment with sequential application of nitrogen fertilizer coupled with moderate field drought for root-vigor and tiller promotion before and after harvesting of the main crop, significantly improved the effective tillers from low position nodes. This in turn increased the effective panicles per plant and grains per panicle by reducing the influence of artificial crushing damage on rice stubble and achieving a high yield of the regenerated rice. Furthermore, the partitioning of 13C assimilates to the residual stubble and its axillary buds were significantly improved at the mature stage of the main crop, while the translocation rate to roots and rhizosphere soil was reduced at the later growth stage of ratooning season rice. This was triggered by the metabolism of hormones and polyamines at the stem base regulated by the interaction of water and fertilizer at this time. We therefore suggest that to achieve a high yield of ratoon rice with low stubble height under mechanized harvesting, the timely application of nitrogen fertilizer is fundamental,coupled with moderate field drying for root-vigor preservation and tiller promotion before and after the mechanical harvesting of the main crop.

Influence of heat treatment on microstructure,mechanical and corrosion behavior of WE43 alloy fabricated by laser-beam powder bed fusion

Magnesium(Mg)alloys are considered to be a new generation of revolutionary medical metals.Laser-beam powder bed fusion(PBF-LB)is suitable for fabricating metal implants withpersonalized and complicated structures.However,the as-built part usually exhibits undesirable microstructure and unsatisfactory performance.In this work,WE43 parts were firstly fabricated by PBF-LB and then subjected to heat treatment.Although a high densification rate of 99.91%was achieved using suitable processes,the as-built parts exhibited anisotropic and layeredmicrostructure with heterogeneously precipitated Nd-rich intermetallic.After heat treatment,fine and nano-scaled Mg24Y5particles were precipitated.Meanwhile,theα-Mg grainsunderwent recrystallization and turned coarsened slightly,which effectively weakened thetexture intensity and reduced the anisotropy.As a consequence,the yield strength and ultimate tensile strength were significantly improved to(250.2±3.5)MPa and(312±3.7)MPa,respectively,while the elongation was still maintained at a high level of 15.2%.Furthermore,the homogenized microstructure reduced the tendency of localized corrosion and favoredthe development of uniform passivation film.Thus,the degradation rate of WE43 parts was decreased by an order of magnitude.Besides,in-vitro cell experiments proved their favorable biocompatibility.

Drug resistance mechanisms in cancers:Execution of prosurvival strategies

One of the quintessential challenges in cancer treatment is drug resistance.Several mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be discovered.The phenomenon of cancer drug resistance is now widespread,with approximately 90% of cancer-related deaths associated with drug resistance.Despite significant advances in the drug discovery process,the emergence of innate and acquired mechanisms of drug resistance has impeded the progress in cancer therapy.Therefore,understanding the mechanisms of drug resistance and the various pathways involved is integral to treatment modalities.In the present review,I discuss the different mechanisms of drug resistance in cancer cells,including DNA damage repair,epithelial to mesenchymal transition,inhibition of cell death,alteration of drug targets,inactivation of drugs,deregulation of cellular energetics,immune evasion,tumor-promoting inflammation,genome instability,and other contributing epigenetic factors.Furthermore,I highlight available treatment options and conclude with future directions.

To explore the mechanism of Yigong San anti-gastric cancer and immune regulation

BACKGROUND Yigong San(YGS)is a representative prescription for the treatment of digestive disorders,which has been used in clinic for more than 1000 years.However,the mechanism of its anti-gastric cancer and regulate immunity are still remains unclear.AIM To explore the mechanism of YGS anti-gastric cancer and immune regulation.METHODS Firstly,collect the active ingredients and targets of YGS,and the differentially expressed genes of gastric cancer.Secondly,constructed a protein-protein interaction network between the targets of drugs and diseases,and screened hub genes.Then the clinical relevance,mutation and repair,tumor microenvironment and drug sensitivity of the hub gene were analyzed.Finally,molecular docking was used to verify the binding ability of YGS active ingredient and hub genes.RESULTS Firstly,obtained 55 common targets of gastric cancer and YGS.The Kyoto Encyclopedia of Genes and Genomes screened the microtubule-associated protein kinase signaling axis as the key pathway and IL6,EGFR,MMP2,MMP9 and TGFB1 as the hub genes.The 5 hub genes were involved in gastric carcinogenesis,staging,typing and prognosis,and their mutations promote gastric cancer progression.Finally,molecular docking results confirmed that the components of YGS can effectively bind to therapeutic targets.CONCLUSION YGS has the effect of anti-gastric cancer and immune regulation.

Deep Insight of Design,Mechanism,and Cancer Theranostic Strategy of Nanozymes

Since the discovery of enzyme-like activity of Fe3O4 nanoparticles in 2007,nanozymes are becoming the promising substitutes for natural enzymes due to their advantages of high catalytic activity,low cost,mild reaction conditions,good stability,and suitable for large-scale production.Recently,with the cross fusion of nanomedicine and nanocatalysis,nanozyme-based theranostic strategies attract great attention,since the enzymatic reactions can be triggered in the tumor microenvironment to achieve good curative effect with substrate specificity and low side effects.Thus,various nanozymes have been developed and used for tumor therapy.In this review,more than 270 research articles are discussed systematically to present progress in the past five years.First,the discovery and development of nanozymes are summarized.Second,classification and catalytic mechanism of nanozymes are discussed.Third,activity prediction and rational design of nanozymes are focused by highlighting the methods of density functional theory,machine learning,biomimetic and chemical design.Then,synergistic theranostic strategy of nanozymes are introduced.Finally,current challenges and future prospects of nanozymes used for tumor theranostic are outlined,including selectivity,biosafety,repeatability and stability,in-depth catalytic mechanism,predicting and evaluating activities.

Instability mechanism of mining roadway passing through fault at different angles in kilometre-deep mine and control measures of roof cutting and NPR cables

The angle α between the fault strike and the axial direction of the roadway produces different damage characteristics. In this paper, the research methodology includes theoretical analyses, numerical simulations and field experiments in the context of the Daqiang coal mine located in Shenyang, China. The stability control countermeasure of "pre-splitting cutting roof + NPR anchor cable"(PSCR-NPR) is simultaneously proposed. According to the different deformation characteristics of the roadway, the faults are innovatively classified into three types, with α of type I being 0°-30°, α of type II being 30°-60°, and α of type III being 60°-90°. The full-cycle stress evolution paths during mining roadway traverses across different types of faults are investigated by numerical simulation. Different pinch angles α lead to high stress concentration areas at different locations in the surrounding rock. The non-uniform stress field formed in the shallow surrounding rock is an important reason for the instability of the roadway. The pre-cracked cut top shifted the high stress region to the deep rock mass and formed a low stress region in the shallow rock mass. The high prestressing NPR anchor cable transforms the non-uniform stress field of the shallow surrounding rock into a uniform stress field. PSCR-NPR is applied in the fault-through roadway of Daqiang mine. The low stress area of the surrounding rock was enlarged by 3-7 times, and the cumulative convergence was reduced by 45%-50%. It provides a reference for the stability control of the deep fault-through mining roadway.

Molecular Mechanism and Molecular Design of Lubricating Oil Antioxidants

To overcome the limitations of traditional experimental“trial and error”methods in lubricant additive design,a new molecular design method based on molecular structure parameters is established here.The molecular mechanism of the antioxidant reaction of hindered phenol,diphenylamine,and alkyl sulfide are studied via molecular simulations.Calculation results show that the strong electron-donating ability and high hydrogen-donating activity of the antioxidant molecule and the low hydrogen-abstracting activity of free radicals formed after dehydrogenation are the internal molecular causes of the shielding of phenol and diphenylamine from scavenging peroxy free radicals,and the strong electron-donating ability is the internal molecular cause of the high activity of thioether in decomposing alkyl hydrogen peroxide.Based on this antioxidant molecular mechanism,a molecular design rule of antioxidant is proposed,namely“high EHOMO,large Q(S),low bond dissociation energy BDE(O—H)and BDE(N—H)”.Two new antioxidants,PAS-I and PAS-II,are designed and prepared by chemical bonding of hindered phenol,diphenylamine,and sulfur atoms.Experimental results show that these antioxidants both have excellent antioxidant effects in lubricating oil,and that PAS-II is the superior antioxidant,consistent with theoretical predictions.

Recent research progress in the mechanism and suppression of fusion welding-induced liquation cracking of nickel based superalloys

Nickel-based superalloys are extensively used in the crucial hot-section components of industrial gas turbines,aeronautics,and astronautics because of their excellent mechanical properties and corrosion resistance at high temperatures.Fusion welding serves as an effective means for joining and repairing these alloys;however,fusion welding-induced liquation cracking has been a challenging issue.This paper comprehensively reviewed recent liquation cracking,discussing the formation mechanisms,cracking criteria,and remedies.In recent investigations,regulating material composition,changing the preweld heat treatment of the base metal,optimizing the welding process parameters,and applying auxiliary control methods are effective strategies for mitigating cracks.To promote the application of nickel-based superalloys,further research on the combination impact of multiple elements on cracking prevention and specific quantitative criteria for liquation cracking is necessary.

Preliminary discussion on the ignition mechanism of exploding foil initiators igniting boron potassium nitrate

Exploding foil initiator(EFI)is a kind of advanced device for initiating explosives,but its function is unstable when it comes to directly igniting pyrotechnics.To solve the problem,this research aims to reveal the ignition mechanism of EFIs directly igniting pyrotechnics.An oscilloscope,a photon Doppler velocimetry,and a plasma spectrum measurement system were employed to obtain information of electric characteristics,impact pressure,and plasma temperature.The results of the electric characteristics and the impact pressure were inconsistent with ignition results.The only thing that the ignition success tests had in common was that their plasma all had a relatively long period of high-temperature duration(HTD).It eventually concludes that the ignition mechanism in this research is the microconvection heat transfer rather than the shock initiation,which differs from that of exploding foil initiators detonating explosives.Furthermore,the methods for evaluating the ignition success of semiconductor bridge initiators are not entirely applicable to the tests mentioned in this paper.The HTD is the critical parameter for judging the ignition success,and it is influenced by two factors:the late time discharge and the energy of the electric explosion.The longer time of the late time discharge and the more energy of the electric explosion,the easier it is to expand the HTD,which improves the probability of the ignition success.

Efficient Unsupervised Image Stitching Using Attention Mechanism with Deep Homography Estimation

Traditional feature-based image stitching techniques often encounter obstacles when dealing with images lackingunique attributes or suffering from quality degradation. The scarcity of annotated datasets in real-life scenesseverely undermines the reliability of supervised learning methods in image stitching. Furthermore, existing deeplearning architectures designed for image stitching are often too bulky to be deployed on mobile and peripheralcomputing devices. To address these challenges, this study proposes a novel unsupervised image stitching methodbased on the YOLOv8 (You Only Look Once version 8) framework that introduces deep homography networksand attentionmechanisms. Themethodology is partitioned into three distinct stages. The initial stage combines theattention mechanism with a pooling pyramid model to enhance the detection and recognition of compact objectsin images, the task of the deep homography networks module is to estimate the global homography of the inputimages consideringmultiple viewpoints. The second stage involves preliminary stitching of the masks generated inthe initial stage and further enhancement through weighted computation to eliminate common stitching artifacts.The final stage is characterized by adaptive reconstruction and careful refinement of the initial stitching results.Comprehensive experiments acrossmultiple datasets are executed tometiculously assess the proposed model. Ourmethod’s Peak Signal-to-Noise Ratio (PSNR) and Structure Similarity Index Measure (SSIM) improved by 10.6%and 6%. These experimental results confirm the efficacy and utility of the presented model in this paper.

An Underwater Target Detection Algorithm Based on Attention Mechanism and Improved YOLOv7

For underwater robots in the process of performing target detection tasks,the color distortion and the uneven quality of underwater images lead to great difficulties in the feature extraction process of the model,which is prone to issues like error detection,omission detection,and poor accuracy.Therefore,this paper proposed the CER-YOLOv7(CBAM-EIOU-RepVGG-YOLOv7)underwater target detection algorithm.To improve the algorithm’s capability to retain valid features from both spatial and channel perspectives during the feature extraction phase,we have added a Convolutional Block Attention Module(CBAM)to the backbone network.The Reparameterization Visual Geometry Group(RepVGG)module is inserted into the backbone to improve the training and inference capabilities.The Efficient Intersection over Union(EIoU)loss is also used as the localization loss function,which reduces the error detection rate and missed detection rate of the algorithm.The experimental results of the CER-YOLOv7 algorithm on the UPRC(Underwater Robot Prototype Competition)dataset show that the mAP(mean Average Precision)score of the algorithm is 86.1%,which is a 2.2%improvement compared to the YOLOv7.The feasibility and validity of the CER-YOLOv7 are proved through ablation and comparison experiments,and it is more suitable for underwater target detection.