Experimental study on the effect of flexible joints of a deep-buried tunnel across an active fault under high in-situ stress conditions

During dislocation,a tunnel crossing the active fault will be damaged to varying degrees due to its permanent stratum displacement.Most previous studies did not consider the influence of the tunnel’s deep burial and the high in-situ stress,so the results were not entirely practical.In this paper,the necessity of solving the anti-dislocation problem of deep-buried tunnels is systemically discussed.Through the model test of tunnels across active faults,the differences in failures between deep-buried tunnels and shallow-buried tunnels were compared,and the dislocation test of deep-buried segmental tunnels was carried out to analyze the external stress change,lining strain,and failure mode of tunnels.The results are as follows.(1)The overall deformation of deep-buried and shallow-buried tunnels is both Sshaped.The failure mode of deep-buried tunnels is primarily characterized by shear and tensile failure,resulting in significant compressive deformation and a larger damaged area.In contrast,shallow-buried tunnels mainly experience shear failure,with the tunnel being sheared apart at the fault crossing,leading to more severe damage.(2)After the segmental structure design of the deep-buried tunnel,the “S”deformation pattern is transformed into a “ladder”pattern,and the strain of the tunnel and the peak stress of the external rock mass are reduced;therefore,damages are significantly mitigated.(3)Through the analysis of the distribution of cracks in the tunnel lining,it is found that the tunnel without a segmental structure design has suffered from penetrating failure and that cracks affect the entire lining.The cracks in a flexible segmental tunnel affect about 66.6% of the entire length of the tunnel,and cracks in a tunnel with a short segmental tunnel only affect about 33.3% of the entire length of the tunnel.Therefore,a deep-buried tunnel with a short segmental tunnel can yield a better anti-dislocation effect.(4)By comparing the shallow-buried segmental tunnel in previous studies,it is concluded that the shallow-buried segmental tunnel will also suffer from deformation outside the fault zone,while the damages to the deep-buried segmental tunnel are concentrated in the fault zone,so the anti-dislocation protection measures of the deep-buried tunnel shall be provided mainly in the fault zone.The results of the above study can provide theoretical reference and technical support for the design and reinforcement measures of the tunnel crossing active fault under high in-situ stress conditions.

A continuous and long-term in-situ stress measuring method based on fiber optic. Part I: Theory of inverse differential strain analysis

A method for in-situ stress measurement via fiber optics was proposed. The method utilizes the relationship between rock mass elastic parameters and in-situ stress. The approach offers the advantage of long-term stress measurements with high spatial resolution and frequency, significantly enhancing the ability to measure in-situ stress. The sensing casing, spirally wrapped with fiber optic, is cemented into the formation to establish a formation sensing nerve. Injecting fluid into the casing generates strain disturbance, establishing the relationship between rock mass properties and treatment pressure.Moreover, an optimization algorithm is established to invert the elastic parameters of formation via fiber optic strains. In the first part of this paper series, we established the theoretical basis for the inverse differential strain analysis method for in-situ stress measurement, which was subsequently verified using an analytical model. This paper is the fundamental basis for the inverse differential strain analysis method.

Support design method for deep soft-rock tunnels in non-hydrostatic high in-situ stress field

Due to the long-term plate tectonic movements in southwestern China,the in-situ stress field in deep formations is complex.When passing through deep soft-rock mass under non-hydrostatic high in-situ stress field,tunnels will suffer serious asymmetric deformation.There is no available support design method for tunnels under such a situation in existing studies to clarify the support time and support stiffness.This study first analyzed the mechanical behavior of tunnels in non-hydrostatic in-situ stress field and derived the theoretical equations of the ground squeezing curve(GSC)and ground loosening curve(GLC).Then,based on the convergence confinement theory,the support design method of deep soft-rock tunnels under non-hydrostatic high in-situ stress field was established considering both squeezing and loosening pressures.In addition,this method can provide the clear support time and support stiffness of the second layer of initial support.The proposed design method was applied to the Wanhe tunnel of the China-Laos railway in China.Monitoring data indicated that the optimal support scheme had a good effect on controlling the tunnel deformation in non-hydrostatic high in-situ stress field.Field applications showed that the secondary lining could be constructed properly.

Performance of water-coupled charge blasting under different in-situ stresses

Water-coupled charge blasting is a promising technique to efficiently break rock masses.In this study,numerical models of double boreholes with water-coupled charge are established using LS-DYNA and are calibrated by the tests of rock masses subjected to explosion loads to examine its performance.The crack levels of rock mass induced by water-coupled charge blasting and air-coupled charge blasting are first compared.It is found that water-coupled charge blasting is more appropriate to fracture deep rock mass than air-coupled charge blasting.In addition,the effects of rock properties,water-coupled charge coefficients,and borehole connection angles on the performance of water-coupled charge blasting are investigated.The results show that rock properties and water-coupled charge coefficients can greatly influence the crack and fragmentation levels of rock mass induced by water-coupled charge blasting under uniform and non-uniform in-situ stresses.However,changing borehole-connection angles can only affect crack and fragmentation levels of rock mass under non-uniform in-situ stresses but barely affect those under uniform in-situ stresses.A formula is finally proposed by considering the above-mentioned factors to provide the design suggestion of water-coupled charge blasting to fracture rock mass with different in-situ stresses.

Influences of clean fracturing fluid viscosity and horizontal in-situ stress difference on hydraulic fracture propagation and morphology in coal seam

The viscosity of fracturing fluid and in-situ stress difference are the two important factors that affect the hydraulic fracturing pressure and propagation morphology. In this study, raw coal was used to prepare coal samples for experiments, and clean fracturing fluid samples were prepared using CTAB surfactant. A series of hydraulic fracturing tests were conducted with an in-house developed triaxial hydraulic fracturing simulator and the fracturing process was monitored with an acoustic emission instrument to analyze the influences of fracturing fluid viscosity and horizontal in-situ stress difference on coal fracture propagation. The results show that the number of branched fractures decreased, the fracture pattern became simpler, the fractures width increased obviously, and the distribution of AE event points was concentrated with the increase of the fracturing fluid viscosity or the horizontal in-situ stress difference. The acoustic emission energy decreases with the increase of fracturing fluid viscosity and increases with the increase of horizontal in situ stress difference. The low viscosity clean fracturing fluid has strong elasticity and is easy to be compressed into the tip of fractures, resulting in complex fractures. The high viscosity clean fracturing fluids are the opposite. Our experimental results provide a reference and scientific basis for the design and optimization of field hydraulic fracturing parameters.

Conditional Generative Adversarial Network Enabled Localized Stress Recovery of Periodic Composites

Structural damage in heterogeneousmaterials typically originates frommicrostructures where stress concentration occurs.Therefore,evaluating the magnitude and location of localized stress distributions within microstructures under external loading is crucial.Repeating unit cells(RUCs)are commonly used to represent microstructural details and homogenize the effective response of composites.This work develops a machine learning-based micromechanics tool to accurately predict the stress distributions of extracted RUCs.The locally exact homogenization theory efficiently generates the microstructural stresses of RUCs with a wide range of parameters,including volume fraction,fiber/matrix property ratio,fiber shapes,and loading direction.Subsequently,the conditional generative adversarial network(cGAN)is employed and constructed as a surrogate model to establish the statistical correlation between these parameters and the corresponding localized stresses.The stresses predicted by cGAN are validated against the remaining true data not used for training,showing good agreement.This work demonstrates that the cGAN-based micromechanics tool effectively captures the local responses of composite RUCs.It can be used for predicting potential crack initiations starting from microstructures and evaluating the effective behavior of periodic composites.

Effect of boundary conditions on shakedown analysis of heterogeneous materials

The determination of the ultimate load-bearing capacity of structures made of elastoplastic heterogeneous materials under varying loads is of great importance for engineering analysis and design. Therefore, it is necessary to accurately predict the shakedown domains of these materials. The static shakedown theorem, also known as Melan's theorem, is a fundamental method used to predict the shakedown domains of structures and materials. Within this method, a key aspect lies in the construction and application of an appropriate self-equilibrium stress field(SSF). In the structural shakedown analysis, the SSF is typically constructed by governing equations that satisfy no external force(NEF) boundary conditions. However, we discover that directly applying these governing equations is not suitable for the shakedown analysis of heterogeneous materials. Researchers must consider the requirements imposed by the Hill-Mandel condition for boundary conditions and the physical significance of representative volume elements(RVEs). This paper addresses this issue and demonstrates that the sizes of SSFs vary under different boundary conditions, such as uniform displacement boundary conditions(DBCs), uniform traction boundary conditions(TBCs), and periodic boundary conditions(PBCs). As a result, significant discrepancies arise in the predicted shakedown domain sizes of heterogeneous materials. Built on the demonstrated relationship between SSFs under different boundary conditions, this study explores the conservative relationships among different shakedown domains, and provides proof of the relationship between the elastic limit(EL) factors and the shakedown loading factors under the loading domain of two load vertices. By utilizing numerical examples, we highlight the conservatism present in certain results reported in the existing literature. Among the investigated boundary conditions, the obtained shakedown domain is the most conservative under TBCs.Conversely, utilizing PBCs to construct an SSF for the shakedown analysis leads to less conservative lower bounds, indicating that PBCs should be employed as the preferred boundary conditions for the shakedown analysis of heterogeneous materials.

Least Square Finite Element Model for Analysis of Multilayered Composite Plates under Arbitrary Boundary Conditions

Laminated composites are widely used in many engineering industries such as aircraft, spacecraft, boat hulls, racing car bodies, and storage tanks. We analyze the 3D deformations of a multilayered, linear elastic, anisotropic rectangular plate subjected to arbitrary boundary conditions on one edge and simply supported on other edge. The rectangular laminate consists of anisotropic and homogeneous laminae of arbitrary thicknesses. This study presents the elastic analysis of laminated composite plates subjected to sinusoidal mechanical loading under arbitrary boundary conditions. Least square finite element solutions for displacements and stresses are investigated using a mathematical model, called a state-space model, which allows us to simultaneously solve for these field variables in the composite structure’s domain and ensure that continuity conditions are satisfied at layer interfaces. The governing equations are derived from this model using a numerical technique called the least-squares finite element method (LSFEM). These LSFEMs seek to minimize the squares of the governing equations and the associated side conditions residuals over the computational domain. The model is comprised of layerwise variables such as displacements, out-of-plane stresses, and in- plane strains, treated as independent variables. Numerical results are presented to demonstrate the response of the laminated composite plates under various arbitrary boundary conditions using LSFEM and compared with the 3D elasticity solution available in the literature.

Numerical analysis on mechanical difference of sandstone under in-situ stress,pore pressure preserved environment at depth

Deep in-situ rock mechanics considers the influence of the in-situ environment on mechanical properties,differentiating it from traditional rock mechanics.To investigate the effect of in-situ stress,pore pressure preserved environment on the mechanical difference of sandstone,four tests are numerically modeled by COMSOL:conventional triaxial test,conventional pore pressure test,in-situ stress restoration and reconstruction test,and in-situ pore pressure-preserved test(not yet realized in the laboratory).The in-situ stress restoration parameter is introduced to characterize the recovery effect of in-situ stress on elastic modulus and heterogeneous distribution of sandstone at different depths.A random function and nonuniform pore pressure coefficient are employed to describe the non-uniform distribution of pore pressure in the in-situ environment.Numerical results are compared with existing experimental data to validate the models and calibrate the numerical parameters.By extracting mechanical parameters from numerical cores,the stress-strain curves of the four tests under different depths,in-situ stress and pore pressure are compared.The influence of non-uniform pore pressure coefficient and depth on the peak strength of sandstone is analyzed.The results show a strong linear relationship between the in-situ stress restoration parameter and depth,effectively characterizing the enhanced effect of stress restoration and reconstruction methods on the elastic modulus of conventional cores at different depths.The in-situ pore pressurepreserved test exhibits lower peak stress and peak strain compared to the other three tests,and sandstone subjected to non-uniform pore pressure is more prone to plastic damage and failure.Moreover,the influence of non-uniform pore pressure on peak strength gradually diminished with increasing depth.

Prediction Research of Deformation Modulus of Weak Rock Zone under In-situ Conditions

Weak rock zone (soft interlayer, fault zone and soft rock) is the highlight of large-scale geological engineering research. It is an important boundary for analysis of rock mass stability. Weak rock zone has been formed in a long geological period, and in this period, various rocks have undergone long-term consolidation of geostatic stress and tectonic stress; therefore, under in-situ conditions, their density and modulus of deformation are relatively high. Due to its fragmentary nature, once being exposed to the earth's surface, the structure of weak rock zone will soon be loosened, its density will be reduced, and its modulus of deformation will also be reduced significantly. Generally, weak rock zone can be found in large construction projects, especially in the dam foundation rocks of hydropower stations. These rocks cannot be eliminated completely by excavation. Furthermore, all tests nowadays are carried out after the exposure of weak rock zone, modulus of deformation under in-situ conditions cannot be revealed. In this paper, a test method explored by the authors has been introduced. This method is a whole multilayered medium deformation method. It is unnecessary to eliminate the relatively complete rocks covering on weak rock zone. A theoretical formula to obtain the modulus of deformation in various mediums has also been introduced. On-site comparative trials and indoor deformation modulus tests under equivalent density conditions have been carried out. We adopted several methods for the prediction researches of the deformation modulus of weak rock zone under in-situ conditions, and revealed a fact that under in-situ conditions, the deformation modulus of weak rock zone are several times higher than the test results obtained after the exposure. In a perspective of geological engineering, the research findings have fundamentally changed peoples' concepts on the deformation modulus of weak rock zone, provided important theories and methods for precise definition of deformation modulus of deep weak rock zone under cap rock conditions, as well as for reasonable engineering applications.

Discrete Stress-strength Interference Model of Reliability Analysis under Multi-operating Conditions

The conventional stress-strength interference（SSI） model is a basic model for reliability analysis of mechanical components. In this model, the component reliability is defined as the probability of the strength being larger than the stress, where the component stress is generally represented by a single random variable（RV）. But for a component under multi-operating conditions, its reliability can not be calculated directly by using the SSI model. The problem arises from that the stress on a component under multi-operating conditions can not be described by a single RV properly. Current research concerning the SSI model mainly focuses on the calculation of the static or dynamic reliability of the component under single operation condition. To evaluate the component reliability under multi-operating conditions, this paper uses multiple discrete RVs based on the actual stress range of the component firstly. These discrete RVs have identical possible values and different corresponding probability value, which are used to represent the multi-operating conditions of the component. Then the component reliability under each operating condition is calculated, respectively, by employing the discrete SSI model and the universal generating function technique, and from this the discrete SSI model under multi-operating conditions is proposed. Finally the proposed model is applied to evaluate the reliability of a transmission component of the decelerator installed in an aeroengine. The reliability of this component during taking-off, cruising and landing phases of an aircraft are calculated, respectively. With this model, a basic method for reliability analysis of the component under complex load condition is provided, and the application range of the conventional SSI model is extended.

A critical review on the developments of rock support systems in high stress ground conditions

Extreme ground behaviour in high-stress rock masses such as rockburst prone and squeezing ground conditions are encountered in a range of underground projects both in civil and mining applications.The occurrence of such ground behaviour types are difficult to predict and special design and construction measures must be taken to control them.Determining the most appropriate support system in such grounds is one of the major challenges for ground control engineers because there are many contributing factors to be considered,such as the rock mass parameters,the stress condition,the type and performance of the support systems,the condition of major geological structures and the size and geometry of the underground excavation.The main characteristics and support requirements of rockburst-prone and squeezing ground conditions are herein critically reviewed and characteristics of support functions are discussed.Different types of energy-absorbing rockbolts and other support elements applicable for ground support in burst-prone and squeezing grounds are introduced.Important differences in the choice and economics of ground support strategies in high-stress ground conditions between civil tunnels and mining excavations are discussed.Ground support benchmarking data and mitigation measures for mines and civil tunnels in burst-prone,squeezing and heavily swelling grounds conditions are briefly presented by some examples in practice.

Effects of imperfect experimental conditions on stress waves in SHPB experiments

Experimental and numerical simulations were undertaken to estimate the effects of imperfect conditions on stress waves in split Hopkinson pressure bar （SHPB） experiments. The photonic Doppler velocimetry （PDV） measurement results show that the rise and fall times of an incident wave increases with an increasing inclination angle; also, the fluctuations of the incident wave disappear gradually with the increase of inclination angle. The following characteristics for various defects in the SHPB were obtained by numerical simulation： （1） the influence of a curved bar was negligible; （2） misalignment modestly affects the fluctuation characteristics, and bending waves were generated at this condition; （3） inclination and indentation of the impact end- surface had a great impact on the incident waves, and both of them increase the rise time of the incident wave by increasing the degree of defects. In view of the results, misalignment, inclination, and indentation in SHPB experiments should be minimized.

Stiffness Degradation of Undisturbed Saturated Soft Clay in the Yangtze Estuary Under Complex Stress Conditions

Stiffness degradation will occur due to the generation of accumulated pore pressure in saturated soft clays under cyclic loading. The soil static-dynamic multi-purpose triaxial and torsional shear apparatus in Dalian University of Technology was employed to perform different types of test on the saturated soft marine clay in the Yangtze Estuary. Undisturbed samples of the clay were subjected to undrained cyclic vertical and torsional coupling shear and cyclic torsional shear after three-directional anisotropic consolidation with different initial consolidation parameters. Investigated were the effects of the initial orientation angle of the major principal stress, initial ratio of deviatoric stress, initial coefficient of intermediate principal stress and continuous rotation of principal stress axes on the stiffness degradation. It is found that the degradation index decreases （or degradation degree increases） significantly with increasing initial orientation angle of the major principal stress and initial ratio of deviatoric stress. Compared with the effects of the initial orientation angle of the major principal stress and initial ratio of deviatoric stress, the effect of initial coefficient of intermediate principal stress is less evident and this trend is more clearly reflected by the results of the cyclic torsional shear tests than those of the cyclic coupling shear tests. At the same cycle number, the degradation index obtained from the cyclic torsional shear test is higher than that from the cyclic coupling shear test. The main reason is that the continuous rotation in principal stress directions during cyclic coupling shear damages the original structure of the soil more than the cyclic torsional shear does.Based on a series of experiments, a mathematical model for stiffness degradation is proposed and the relevant parameters are determined.

Effects of stress conditions on rheological properties of granular soil in large triaxial rheology laboratory tests

In order to study the rheological properties of red stone granular soil,a series of rheological experiments were executed on large tri-axial rheological apparatus.Under 100,200 and 300 kPa confining stress conditions,the rheological tests were carried out.These experiment results showed that the stress conditions,especially the stress level were the critical influencing factors of the rheological deformation properties.Under the low stress level(S=0.1),the granular soil showed the elastic properties,and there was no obvious rheological deformation.Under the middle stress level(0.2<S≤0.6),creep curves showed the linear viscoelastic rheological properties.However,under the high stress level(S>0.8) creep curves showed the non-linear viscous plastic rheological properties.Especially,under the stress level of S=1.0,the accelerated rheological phase of creep curves occurred at early time with a trend of failure.The stress level had obvious effects on the final rheological deformation of the soil sample,and the final rheological deformation increments nonlinearly increased with stress level.The final rheological deformation increment and step was little under low stress level,while it became large under high stress level,which showed the nonlinearly rheological properties of the granular soil.The confining pressure also had direct effects on final rheological deformation,and the final rheological deformation linearly increased with confining pressure increments.

Stress redistribution of simply supported reinforced concrete beams under fire conditions

This study presents experimental and numerical investigations of simply supported steel reinforced concrete(RC)beams under fire.The temperature field of cross sections,the vertical deflection at mid-span,and specifically the axial expansion displacement at beam-ends were measured during the fire tests.A novel finite element(FE)model of a RC beam under fire was developed,in which the water loss in the heat transfer analysis and the concrete transient strain in the mechanical analysis were considered.Based on the validated FE model proposed in this study,parametric studies were conducted to investigate the effects of the beam type,the protective layer thickness,and the load ratio on the thermal and mechanical behavior of simply supported RC beams.It was found that greater fire resistance and fire performance of girder beams in comparison to secondary beams contributed to the non-structural reinforcements,which effectively compensated for the reduced tensile capacities of structural reinforcements because of the degradation of the material properties.In addition,the history of normal stress distributions of concrete under fire can be divided into three phases:expansion,stress redistribution and plateau phases.

Measures for controlling large deformations of underground caverns under high in-situ stress condition--A case study of JinpingⅠhydropower station

The Jinping I hydropower station is a huge water conservancy project consisting of the highest concrete arch dam to date in the world and a highly complex and large underground powerhouse cavern. It is located on the right bank with extremely high in-situ stress and a few discontinuities observed in surrounding rock masses. The problems of rock mass deformation and failure result in considerable challenges related to project design and construction and have raised a wide range of concerns in the fields of rock mechanics and engineering. During the excavation of underground caverns, high in-situ stress and relatively low rock mass strength in combination with large excavation dimensions lead to large deformation of the surrounding rock mass and support. Existing experiences in excavation and support cannot deal with the large deformation of rock mass effectively, and further studies are needed. In this paper, the geological conditions, layout of caverns, and design of excavation and support are first introduced, and then detailed analyses of deformation and failure characteristics of rocks are presented. Based on this, the mechanisms of deformation and failure are discussed, and the support adjustments for controlling rock large deformation and subsequent excavation procedures are proposed. Finally, the effectiveness of support and excavation adjustments to maintain the stability of the rock mass is verified. The measures for controlling the large deformation of surrounding rocks enrich the practical experiences related to the design and construction of large underground openings, and the construction of caverns in the Jinping I hydropower station provides a good case study of large-scale excavation in highly stressed ground with complex geological structures, as well as a reference case for research on rock mechanics.

Effects of displacement boundary conditions on thermal deformation in thermal stress problems

Most computational structural engineers are paying more attention to applying loads rather than to DBCs （Displacement Boundary Conditions） because most static stable mechanical structures are working under already prescribed displacement boundary conditions. In all of the computational analysis of solving a system of algebraic equations, such as FEM （Finite Element Method）, three translational and three rotational degrees of freedom （DOF） should be constrained （by applying DBCs） before solving the system of algebraic equation in order to prevent rigid body motions of the analysis results （singular problem）. However, it is very difficult for an inexperienced engineer or designer to apply proper DBCs in the case of thermal stress analysis where no prescribed DBCs or constraints exist, for example in water quenching for heat treatment. Moreover, improper DBCs cause incorrect solutions in thermal stress analysis, such as stress concentration or unreasonable deformation phases. To avoid these problems, we studied a technique which performs the thermal stress analysis without any DBCs; and then removes rigid body motions from the deformation results in a post process step as the need arises. The proposed technique makes it easy to apply DBCs and prevent the error caused by improper DBCs. We proved it was mathematically possible to solve a system of algebraic equations without a step of applying DBCs. We also compared the analysis results with those of a traditional procedure for real castings.

<i>In Vitro</i>Germination and Early Vegetative Growth of Five Tomato (<i>Solanum lycopersicum</i>L.) Varieties under Water Stress Conditions

Water is the main limiting factor in the cultivation of tomato (Solanum lycopersicum L.) in Senegal. Thus, the selection of varieties tolerant to water stress would be an alternative solution for their production. In vitro germination, growth, total chlorophyll and proline levels were studied in five varieties of tomato subjected to increasing osmotic pressures (0, 5, 10 and 15 kPa) thanks to the PEG-8000 incorporated in an MS/2 medium for 30 days. A strong sensitivity to water stress for in vitro seed germination in the Rodeo variety (41%) is recorded at 5 kPa and maintained at 15 kPa (20.83%) while it was only noticed at 15 kPa in the other tomato varieties. The Xewel and Lady Nema varieties obtained the smallest reductions in the number of leaves of vitroplants, with 30.79% and 27.97% at 15 kPa, respectively, and the Rodeo variety recorded a reduction of 35.97%. From 5 kPa, the varieties record reductions in the number of secondary roots of more than 15%. The effect of osmotic pressures on decreasing the taproot height and length is not significant. The Xewel variety had the highest average fresh (0.483 g) and dry (0.082 g) weights of the aerial part at 15 kPa and the Rodeo variety had the lowest ones (0.308 g and 0.0501 g). The Lady Nema variety had the highest average fresh (0.171 g) and dry (0.039 g) root weights and the Rodeo variety had the lowest ones (0.086 and 0.020 g). The vitroplants of Rodeo variety recorded the highest decreases in total chlorophyll contents at all osmotic pressures and the lowest increase in proline content (53.37%) at 15 kPa. A contrario, the Xewel variety recorded the greatest increase in proline content (116.26%). Ultimately, the vitroplants of Lady Nema and Xewel varieties were more tolerant to water stress, the Ganila and Mongal varieties were moderately tolerant and the Rodeo variety was the most sensitive.

Optimization of Extraction Conditions of Pomegranate Peel Polyphenols and Its Protective Effect on Acute Alcoholic Liver Injury in Mice

[Objectives]This study was conducted to explore the optimization of ultrasonic-assisted organic solvent extraction of pomegranate peel polyphenols(PPPs),and to study the protective effect of PPPs on acute alcoholic liver injury in mice.[Methods]The optimal extraction conditions of PPPs were determined by single factor and orthogonal experiments,and an acute alcoholic liver injury model in mice was established.Bifendate was used as the positive control group to investigate the protective effect of low,medium and high doses of PPPs on acute alcoholic liver injury.[Results]The optimum extraction process parameters were followed as 60%ethanol concentration,solid-liquid ratio of 1:40(w/v),extraction temperature of 50℃,and extraction time of 1.5 h,and the yield was 1.42%.The results of animal experiments showed that PPPs could effectively reduce the degree of alcoholic liver injury in mice,reduce the levels of serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST),and reduce the inflammation and necrosis of liver tissue in mice.Meanwhile,the total polyphenols from pomegranate peel also significantly reduced the expression levels of malondialdehyde(MDA),tumor necrosis factor(TNF-α)and interleukin-6(IL-6)in mice,and increased the levels of superoxide dismutase(SOD)and reduced glutathione(GSH)in liver tissue of mice,indicating its antioxidant and anti-inflammatory effects,further illustrating its protective effect on alcoholic liver injury.[Conclusions]PPPs could reduce the expression levels of TNF-α,IL-6 and MDA in mice,and increase the expression levels of SOD and GSH to achieve the protective effect on acute alcoholic liver injury in mice.This study will provide new ideas for the development of new anti-alcoholic liver injury drug resources.