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A continuous and long-term in-situ stress measuring method based on fiber optic. Part I: Theory of inverse differential strain analysis
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作者 Kun-Peng Zhang Mian Chen +2 位作者 Chang-Jun Zhao Su Wang Yong-Dong Fan 《Petroleum Science》 SCIE EI CAS CSCD 2024年第2期1171-1189,共19页
A method for in-situ stress measurement via fiber optics was proposed. The method utilizes the relationship between rock mass elastic parameters and in-situ stress. The approach offers the advantage of long-term stres... A method for in-situ stress measurement via fiber optics was proposed. The method utilizes the relationship between rock mass elastic parameters and in-situ stress. The approach offers the advantage of long-term stress measurements with high spatial resolution and frequency, significantly enhancing the ability to measure in-situ stress. The sensing casing, spirally wrapped with fiber optic, is cemented into the formation to establish a formation sensing nerve. Injecting fluid into the casing generates strain disturbance, establishing the relationship between rock mass properties and treatment pressure.Moreover, an optimization algorithm is established to invert the elastic parameters of formation via fiber optic strains. In the first part of this paper series, we established the theoretical basis for the inverse differential strain analysis method for in-situ stress measurement, which was subsequently verified using an analytical model. This paper is the fundamental basis for the inverse differential strain analysis method. 展开更多
关键词 in-situ stress Fiber optic Orthotropic elastic Differential evolution ABAQUS
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Influences of clean fracturing fluid viscosity and horizontal in-situ stress difference on hydraulic fracture propagation and morphology in coal seam
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作者 Gang Wang Shuxin Wang +5 位作者 Yixin Liu Qiming Huang Shengpeng Li Shuliang Xie Jinye Zheng Jiuyuan Fan 《International Journal of Coal Science & Technology》 EI CAS CSCD 2024年第3期159-175,共17页
The viscosity of fracturing fluid and in-situ stress difference are the two important factors that affect the hydraulic fracturing pressure and propagation morphology. In this study, raw coal was used to prepare coal ... The viscosity of fracturing fluid and in-situ stress difference are the two important factors that affect the hydraulic fracturing pressure and propagation morphology. In this study, raw coal was used to prepare coal samples for experiments, and clean fracturing fluid samples were prepared using CTAB surfactant. A series of hydraulic fracturing tests were conducted with an in-house developed triaxial hydraulic fracturing simulator and the fracturing process was monitored with an acoustic emission instrument to analyze the influences of fracturing fluid viscosity and horizontal in-situ stress difference on coal fracture propagation. The results show that the number of branched fractures decreased, the fracture pattern became simpler, the fractures width increased obviously, and the distribution of AE event points was concentrated with the increase of the fracturing fluid viscosity or the horizontal in-situ stress difference. The acoustic emission energy decreases with the increase of fracturing fluid viscosity and increases with the increase of horizontal in situ stress difference. The low viscosity clean fracturing fluid has strong elasticity and is easy to be compressed into the tip of fractures, resulting in complex fractures. The high viscosity clean fracturing fluids are the opposite. Our experimental results provide a reference and scientific basis for the design and optimization of field hydraulic fracturing parameters. 展开更多
关键词 Clean fracturing fluid Hydraulic fracturing VISCOSITY Horizontal in-situ stress difference Hydraulic fracture morphology Acoustic emission
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Accurate models and nutritional strategies for specific oxidative stress factors: Does the dose matter in swine production?
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作者 Changming Hong Yujian Huang +6 位作者 Shuting Cao Li Wang Xuefen Yang Shenglan Hu Kaiguo Gao Zongyong Jiang Hao Xiao 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第2期519-534,共16页
Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxid... Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxidant strategies in relation to oxidative stress-induced pig production,it remains so far largely unsuccessful to develop accurate models and nutritional strategies for specific oxidative stress factors.Here,we discuss the dose and dose intensity of the causes of oxidative stress involving physiological,environmental and dietary factors,recent research models and the antioxidant strategies to provide theoretical guidance for future oxidative stress research in swine. 展开更多
关键词 Accurate models DOSE Nutritional strategies Oxidative stress SWINE
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Economic Stress, Precariousness and Risk of High Blood Pressure: A Descriptive Survey of Life Models within Households of the Central Region of Cameroon
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作者 Jean Ndibi Abanda Ulrich Dama +5 位作者 Viviane Foussouo Ndoungue Anicet Onana Akoa Melkior Fobasso Dzeuta Alphonse Tedonge Asobochia Arsène Emilien Messi Ndzengue Désiré Tchoffo 《Health》 2024年第2期118-130,共13页
Context/Objective: High blood pressure (HBP) currently represents the most widespread chronic non-communicable disease in Cameroon. The increase in its prevalence in the country is the result of multiple factors inclu... Context/Objective: High blood pressure (HBP) currently represents the most widespread chronic non-communicable disease in Cameroon. The increase in its prevalence in the country is the result of multiple factors including economic stress imposed by precariousness, poor living conditions, sources of anxiety, anguish, depression and other behavioral disorders. Economic stress is a globalizing concept that integrates into a purely hermeneutic approach, a particular functioning of the nervous system of an individual who faces employment problems and precarious remuneration conditions. The non-satisfaction by an individual of his basic needs due to insufficient financial means can cause him to become irritable, aggressive, and socially and symbolically isolated, thereby increasing the desire to resort to morbid life models such as excessive consumption of narcotics and other psychoactive substances often associated with high blood pressure. The fight against the emergence of BPH is a complex, multifaceted and multifactorial reality that requires taking into account economic stress. The main objective of this survey is to describe the situation of economic stress within the Cameroonian population, which imposes precariousness and life models at risk of high blood pressure. Specifically, we determined the level of household income and the sources of income. Methods: A cross-sectional survey with a descriptive aim among five hundred households in the Central Region of Cameroon was conducted. A probabilistic technique called simple randomness was used. The number of households to be surveyed was determined indirectly using the Cochrane formula. Data collection in face-to-face mode using a physical questionnaire took place from July 1 to August 31, 2023, after obtaining ethical clearance from the Regional Health Research Ethics Committee, Human from the Center and an administrative authorization for data collection. Regarding their processing, the data was grouped during processing in Excel sheets. Normality and reliability tests of the collected data were carried out. For this, the Chi-square test was used for data with a qualitative value and that of Kolmogorov-Sminorf for data with a quantitative value. Descriptive analysis was possible using R software version 3.2, SPSS version 25.0, XLSTAT 2016, PAST and EXCEL programs from Microsoft Office 2013. Results: The main results highlight economic stress, with 45.60% of households surveyed earning less than US$154 per month;55% of household heads were women in single-parent families;14% of household heads were unemployed, 22% worked in the private sector and 19% were self-employed. This general economic situation leads to precarious living conditions, thereby increasing the risk of high blood pressure among the Cameroonian population. 展开更多
关键词 Economic stress PRECARIOUSNESS High Blood Pressure Life models Households
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U-Net Models for Representing Wind Stress Anomalies over the Tropical Pacific and Their Integrations with an Intermediate Coupled Model for ENSO Studies
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作者 Shuangying Du Rong-Hua Zhang 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第7期1403-1416,共14页
El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been develope... El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been developed to simulate and predict it.In some simplified coupled ocean-atmosphere models,the relationship between sea surface temperature(SST)anomalies and wind stress(τ)anomalies can be constructed by statistical methods,such as singular value decomposition(SVD).In recent years,the applications of artificial intelligence(AI)to climate modeling have shown promising prospects,and the integrations of AI-based models with dynamical models are active areas of research.This study constructs U-Net models for representing the relationship between SSTAs andτanomalies in the tropical Pacific;the UNet-derivedτmodel,denoted asτUNet,is then used to replace the original SVD-basedτmodel of an intermediate coupled model(ICM),forming a newly AI-integrated ICM,referred to as ICM-UNet.The simulation results obtained from ICM-UNet demonstrate their ability to represent the spatiotemporal variability of oceanic and atmospheric anomaly fields in the equatorial Pacific.In the ocean-only case study,theτUNet-derived wind stress anomaly fields are used to force the ocean component of the ICM,the results of which also indicate reasonable simulations of typical ENSO events.These results demonstrate the feasibility of integrating an AI-derived model with a physics-based dynamical model for ENSO modeling studies.Furthermore,the successful integration of the dynamical ocean models with the AI-based atmospheric wind model provides a novel approach to ocean-atmosphere interaction modeling studies. 展开更多
关键词 U-Net models wind stress anomalies ICM integration of AI and physical components
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Stress wave analysis of high-voltage pulse discharge rock fragmentation based on plasma channel impedance model 被引量:1
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作者 黄仕杰 刘毅 +5 位作者 赵勇 徐尤来 林福昌 李化 张钦 李柳霞 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第6期52-64,共13页
High-voltage pulse discharge(HVPD)rock fragmentation controls a plasma channel forming inside the rock by adjusting the electrical parameters,electrode type,etc.In this work,an HVPD rock fragmentation test platform wa... High-voltage pulse discharge(HVPD)rock fragmentation controls a plasma channel forming inside the rock by adjusting the electrical parameters,electrode type,etc.In this work,an HVPD rock fragmentation test platform was built and the test waveforms were measured.Considering the effects of temperature,channel expansion and electromagnetic radiation,the impedance model of the plasma channel in the rock was established.The parameters and initial values of the model were determined by an iterative computational process.The model calculation results can reasonably characterize the development of the plasma channel in the rock and estimate the shock wave characteristics.Based on the plasma channel impedance model,the temporal and spatial distribution characteristics of the radial stress and tangential stress in the rock were calculated,and the rock fragmentation effect of the HVPD was analyzed. 展开更多
关键词 stress wave shock wave plasma channel impedance model rock fragmentation high-voltage pulse discharge
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Numerical modeling of destress blasting for strata separation 被引量:1
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作者 Petr Konicek Tuo Chen Hani S.Mitri 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第9期2238-2249,共12页
Destress blasting(DB)implemented along the perimeter of safety pillars is a special application of destressing in coal longwall mining.The goal is to separate relatively more deformed mined areas from safety pillars,s... Destress blasting(DB)implemented along the perimeter of safety pillars is a special application of destressing in coal longwall mining.The goal is to separate relatively more deformed mined areas from safety pillars,such as shaft pillars or cross-cut pillars,to reduce the transfer of high stresses to the protective pillar.This case study aims to numerically simulate selected destress blasts in the Czech part of the Upper Silesian Coal Basin and examine its impact on stress transfer to the safety pillar area.To separate the area between the protective pillar and the longwall(LW),two fans of five 93-mm blast holes(length of 93e100 m)were drilled from the gate roads into the overburden strata.Each set of blast holes was fired separately in two stages without time delay.The explosive charge(gelatin-type of explosive)of each stage is 3450 kg.The two DB stages were fired when the longwall face was approximately 158 m and 152 m away from the blast.A 3D mine-wide model is built and validated with in situ stress measured with hydrofracturing.Mining and destressing in three 5-m thick coal seams are simulated in the region.Numerical modeling of DB is successfully conducted using a rock fragmentation factor a of 0.05 and a stress reduction/dissipation factor β of 0.95.Buffering of transfer of additional stress from the mining area into the safety pillar is evaluated by comparison of yielding volume before and after DB.It is shown that yielding volume drops after DB by nearly 80%in the area of the destressing panel and near the safety shaft pillar. 展开更多
关键词 Rockburst hazard Destress blasting(DB) Strata separation Safety pillar Numerical modeling Fragmentation factor stress dissipation factor Longwall mining
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Numerical analysis on mechanical difference of sandstone under in-situ stress,pore pressure preserved environment at depth
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作者 Hongwei Zhou Mingyuan Lu +5 位作者 Heping Xie Wenhao Jia Ruidong Peng Yimeng Wang Bocen Chen Pengfei Jing 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第11期1339-1350,共12页
Deep in-situ rock mechanics considers the influence of the in-situ environment on mechanical properties,differentiating it from traditional rock mechanics.To investigate the effect of in-situ stress,pore pressure pres... Deep in-situ rock mechanics considers the influence of the in-situ environment on mechanical properties,differentiating it from traditional rock mechanics.To investigate the effect of in-situ stress,pore pressure preserved environment on the mechanical difference of sandstone,four tests are numerically modeled by COMSOL:conventional triaxial test,conventional pore pressure test,in-situ stress restoration and reconstruction test,and in-situ pore pressure-preserved test(not yet realized in the laboratory).The in-situ stress restoration parameter is introduced to characterize the recovery effect of in-situ stress on elastic modulus and heterogeneous distribution of sandstone at different depths.A random function and nonuniform pore pressure coefficient are employed to describe the non-uniform distribution of pore pressure in the in-situ environment.Numerical results are compared with existing experimental data to validate the models and calibrate the numerical parameters.By extracting mechanical parameters from numerical cores,the stress-strain curves of the four tests under different depths,in-situ stress and pore pressure are compared.The influence of non-uniform pore pressure coefficient and depth on the peak strength of sandstone is analyzed.The results show a strong linear relationship between the in-situ stress restoration parameter and depth,effectively characterizing the enhanced effect of stress restoration and reconstruction methods on the elastic modulus of conventional cores at different depths.The in-situ pore pressurepreserved test exhibits lower peak stress and peak strain compared to the other three tests,and sandstone subjected to non-uniform pore pressure is more prone to plastic damage and failure.Moreover,the influence of non-uniform pore pressure on peak strength gradually diminished with increasing depth. 展开更多
关键词 in-situ pore pressure-preserved ENVIRONMENT Numerical simulation approach Deep in-situ rock mechanics in-situ stress restoration and reconstruction
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Strength Model of Soda Residue Soil Considering Consolidation Stress and Structural Influence
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作者 GONG Xiaolong WANG Yuanzhan CHEN Tong 《Journal of Ocean University of China》 SCIE CAS CSCD 2023年第5期1216-1226,共11页
Soda residue(SR)is a type of industrial waste produced in the soda process with the ammonia-soda method.Applying SR to backfilling solves the land occupation and environmental pollution problems in coastal areas and s... Soda residue(SR)is a type of industrial waste produced in the soda process with the ammonia-soda method.Applying SR to backfilling solves the land occupation and environmental pollution problems in coastal areas and saves material costs for foundation engineering.The strength characteristics of soda residue soil(SRS)under different consolidation conditions are the key points to be solved in the engineering application of SRS.Triaxial compression tests were performed on the undisturbed SRS of Tianjin Port.The shear properties of SRS under different consolidation conditions were then discussed.Meanwhile,a structural strength model(SSM)based on Mohr-Coulomb theory was proposed.SSM reflects the influence of soil structure on undrained strength(Cu)and divides the Cu into the following two parts:friction strength(C_(uf))and original structural strength(C_(u0)).C_(uf)characterizes the magnitude of friction between soil particles,which is related to the consolidation stress.Meanwhile,C_(u0)represents the structural effect on soil strength,which is related to the soil deposition and consolidation processes.SSM was validated by the test data of undisturbed soils.Results reveal that the undisturbed soil generally had a certain C_(u0).Therefore,the SRS strength model was established by combining the experimental law of SRS with SSM.Error analysis shows that the SRS strength model can effectively predict the Cu of undisturbed SRS in Tianjin Port under different consolidation conditions. 展开更多
关键词 soda residue soil triaxial test strength model soil structure consolidation stress
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Stiffness and Shear Stress Distribution of Glulam Beams in Elastic-Plastic Stage:Theory,Experiments and Numerical Modelling
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作者 Lisheng Luo Xinran Xie +2 位作者 Yongqiang Zhang Xiaofeng Zhang Xinyue Cui 《Journal of Renewable Materials》 SCIE EI 2023年第2期791-809,共19页
Traditional methods focus on the ultimate bending moment of glulam beams and the fracture failure of materials with defects,which usually depends on empirical parameters.There is no systematic theoretical method to pr... Traditional methods focus on the ultimate bending moment of glulam beams and the fracture failure of materials with defects,which usually depends on empirical parameters.There is no systematic theoretical method to predict the stiffness and shear distribution of glulam beams in elastic-plastic stage,and consequently,the failure of such glulam beams cannot be predicted effectively.To address these issues,an analytical method considering material nonlinearity was proposed for glulam beams,and the calculating equations of deflection and shear stress distribution for different failure modes were established.The proposed method was verified by experiments and numerical models under the corresponding conditions.Results showed that the theoretical calculations were in good agreement with experimental and numerical results,indicating that the equations proposed in this paper were reliable and accurate for such glulam beams with wood material in the elastic-plastic stage ignoring the influence of mechanic properties in radial and tangential directions of wood.Furthermore,the experimental results reported by the previous studies indicated that the method was applicable and could be used as a theoretical reference for predicting the failure of glulam beams. 展开更多
关键词 Glulam beams load-deflection relationship shear stress distribution elastic-plastic stage numerical model
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Micro sliding friction model considering periodic variation stress distribution of contact surface and experimental verification
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作者 卢晟昊 韩靖宇 阎绍泽 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第4期452-466,共15页
Micro sliding phenomenon widely exists in the operation process of mechanical systems,and the micro sliding friction mechanism is always a research hotspot.In this work,based on the total reflection method,a measuring... Micro sliding phenomenon widely exists in the operation process of mechanical systems,and the micro sliding friction mechanism is always a research hotspot.In this work,based on the total reflection method,a measuring device for interface contact behavior under two-dimensional(2D)vibration is built.The stress distribution is characterized by the light intensity distribution of the contact image,and the interface contact behavior in the 2D vibration process is studied.It is found that the vibration angle of the normal direction of the contact surface and its fluctuation affect the interface friction coefficient,the tangential stiffness,and the fluctuation amplitude of the stress distribution.Then they will affect the change of friction state and energy dissipation in the process of micro sliding.Further,an improved micro sliding friction model is proposed based on the experimental analysis,with the nonlinear change of contact parameters caused by the normal contact stress distribution fluctuation taken into account.This model considers the interface tangential stiffness fluctuation,friction coefficient hysteresis,and stress distribution fluctuation,whose simulation results are consistent well with the experimental results.It is found that considering the nonlinear effect of a certain contact parameter alone may bring a greater error to the prediction of friction behavior.Only by integrating multiple contact parameters can the accuracy of friction prediction is improved. 展开更多
关键词 periodic variation stress distribution micro sliding friction model tangential stiffness experimental analysis STICK-SLIP
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Mechanical stress and deformation analyses of pressurized cylindrical shells based on a higher-order modeling
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作者 S.Mannani L.Collini M.Arefi 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第2期24-33,共10页
In this research,mechanical stress,static strain and deformation analyses of a cylindrical pressure vessel subjected to mechanical loads are presented.The kinematic relations are developed based on higherorder sinusoi... In this research,mechanical stress,static strain and deformation analyses of a cylindrical pressure vessel subjected to mechanical loads are presented.The kinematic relations are developed based on higherorder sinusoidal shear deformation theory.Thickness stretching formulation is accounted for more accurate analysis.The total transverse deflection is divided into bending,shear and thickness stretching parts in which the third term is responsible for change of deflection along the thickness direction.The axisymmetric formulations are derived through principle of virtual work.A parametric study is presented to investigate variation of stress and strain components along the thickness and longitudinal directions.To explore effect of thickness stretching model on the static results,a comparison between the present results with the available results of literature is presented.As an important output,effect of micro-scale parameter is studied on the static stress and strain distribution. 展开更多
关键词 Principle of virtual work Thickness-stretched and shear deformable model stress and strain analyses Cylindrical pressure vessel
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Triaxial creep damage characteristics of sandstone under high crustal stress and its constitutive model for engineering application
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作者 Dongxu Chen Laigui Wang +1 位作者 Pierre Darry Versaillot Chuang Sun 《Deep Underground Science and Engineering》 2023年第3期262-273,共12页
The creep characteristics of rock under high crustal stress are of important influence on the long‐term stability of deep rock engineering.To study the creep characteristics and engineering application of sandstone u... The creep characteristics of rock under high crustal stress are of important influence on the long‐term stability of deep rock engineering.To study the creep characteristics and engineering application of sandstone under high crustal stress,this study constructed nonlinear creep damage(NCD)constitutive mode based on the triaxial graded loading‒unloading creep test of sandstone in the Yuezhishan Tunnel.A numerical NCD constitutive model and a breakable lining(BL)model were developed based on FLAC3D and then applied to the stability analysis of the Yuezhishan Tunnel.Based on the creep test results of sandstone,a power function of creep rate and stress level was constructed,by which the long‐term strength was solved.The results show that the long‐term strength of the red sandstone based on the related function of the steady‐state creep rate and stress level is close to the measured stress value in engineering.The NCD model considering damage factors reflects the instantaneous and viscoelastic plasticity deformation characteristics of the red sandstone.The numerical NCD constitutive model and the BL model can reflect surrounding rock deformation characteristics and lining failure characteristics in practical engineering.The research results provide theoretical references for long‐term stability analysis of rock engineering and the deformation control of surrounding rock under high crustal stress. 展开更多
关键词 creep damage model high stress long‐term strength secondary development tunnel engineering
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In-situ stress of coal reservoirs in the Zhengzhuang area of the southern Qinshui Basin and its effects on coalbed methane development
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作者 Peng Zhang Ya Meng +4 位作者 Chaoying Liu Yuanling Guo Xiangbin Yan Lixue Cai Zhe Cheng 《Energy Geoscience》 2023年第2期17-27,共11页
In-situ stress is a critical factor influencing the permeability of coal reservoirs and the production capacity of coalbed methane(CBM)wells.Accurate prediction of in-situ stress and investigation of its influence on ... In-situ stress is a critical factor influencing the permeability of coal reservoirs and the production capacity of coalbed methane(CBM)wells.Accurate prediction of in-situ stress and investigation of its influence on coal reservoir permeability and production capacity are significant for CBM development.This study investigated the CBM development zone in the Zhengzhuang area of the Qinshui Basin.According to the low mechanical strength of coal reservoirs,this study derived a calculation model of the in-situ stress of coal reservoirs based on the multi-loop hydraulic fracturing method and analyzed the impacts of initial fractures on the calculated results.Moreover,by combining the data such as the in-situ stress,permeability,and drainage and recovery data of CBM wells,this study revealed the spatial distribution patterns of the current in-situ stress of the coal reservoirs and discussed the impacts of the insitu stress on the permeability and production capacity.The results are as follows.(1)Under given fracturing pressure,longer initial fractures are associated with higher calculated maximum horizontal principal stress values.Therefore,ignoring the effects of the initial fractures will cause the calculated values of the in-situ stress to be less than the actual values.(2)As the burial depth increases,the fracturing pressure,closure pressure,and the maximum and minimum horizontal principal stress of the coal reservoirs in the Zhengzhuang area constantly increase.The average gradients of the maximum and minimum horizontal principal stress are 3.17 MPa/100 m and 2.05 MPa/100 m,respectively.(3)Coal reservoir permeability is significantly controlled by the magnitude and state of the current in-situ stress.The coal reservoir permeability decreases exponentially with an increase in the effective principal stress.Moreover,a low lateral pressure coefficient(less than 1)is associated with minor horizontal compressive effects and high coal reservoir permeability.(4)Under similar conditions,such as resource endowments,CBM well capacity is higher in primary structural coal regions with moderate paleotectonic stress modification,low current in-situ stress,and lateral pressure coefficient of less than 1. 展开更多
关键词 in-situ stress Coal reservoir Multi-loop hydraulic fracturing method PERMEABILITY Production capacity
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Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior
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作者 Man Han Deyang Zeng +7 位作者 Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen Wei Yufei Mei Yan Zeng 《Neural Regeneration Research》 SCIE CAS 2025年第1期159-173,共15页
Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral response.Recent studies have shown that brain-derived neurotrophic factor expression in stressed mice ... Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral response.Recent studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and hippocampus.Determining how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress psychopathology.In this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of depression.We focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine circuit.We determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic system.Therefore,BDNF might be a biological indicator regulating stress-related processes in various brain regions. 展开更多
关键词 AMYGDALA chronic mild stress chronic social defeat stress corticolimbic system DEPRESSION HIPPOCAMPUS medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area
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Nonlinear constitutive models of rock structural plane and their applications
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作者 Wenlin Feng Shuangjian Niu +1 位作者 Chunsheng Qiao Dujian Zou 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第3期790-806,共17页
Structural planes play an important role in controlling the stability of rock engineering,and the influence of structural planes should be considered in the design and construction process of rock engineering.In this ... Structural planes play an important role in controlling the stability of rock engineering,and the influence of structural planes should be considered in the design and construction process of rock engineering.In this paper,mechanical properties,constitutive theory,and numerical application of structural plane are studied by a combination method of laboratory tests,theoretical derivation,and program development.The test results reveal the change laws of various mechanical parameters under different roughness and normal stress.At the pre-peak stage,a non-stationary model of shear stiffness is established,and threedimensional empirical prediction models for initial shear stiffness and residual stage roughness are proposed.The nonlinear constitutive models are established based on elasto-plastic mechanics,and the algorithms of the models are developed based on the return mapping algorithm.According to a large number of statistical analysis results,empirical prediction models are proposed for model parameters expressed by structural plane characteristic parameters.Finally,the discrete element method(DEM)is chosen to embed the constitutive models for practical application.The running programs of the constitutive models have been compiled into the discrete element model library.The comparison results between the proposed model and the Mohr-Coulomb slip model show that the proposed model can better describe nonlinear changes at different stages,and the predicted shear strength,peak strain and shear stiffness are closer to the test results.The research results of the paper are conducive to the accurate evaluation of structural plane in rock engineering. 展开更多
关键词 Structural plane Engineering stability ROUGHNESS Normal stress Elasto-plastic constitutive model Discrete element method
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Bayesian partial pooling to reduce uncertainty in overcoring rock stress estimation
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作者 Yu Feng Ke Gao Suzanne Lacasse 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1192-1201,共10页
The state of in situ stress is a crucial parameter in subsurface engineering,especially for critical projects like nuclear waste repository.As one of the two ISRM suggested methods,the overcoring(OC)method is widely u... The state of in situ stress is a crucial parameter in subsurface engineering,especially for critical projects like nuclear waste repository.As one of the two ISRM suggested methods,the overcoring(OC)method is widely used to estimate the full stress tensors in rocks by independent regression analysis of the data from each OC test.However,such customary independent analysis of individual OC tests,known as no pooling,is liable to yield unreliable test-specific stress estimates due to various uncertainty sources involved in the OC method.To address this problem,a practical and no-cost solution is considered by incorporating into OC data analysis additional information implied within adjacent OC tests,which are usually available in OC measurement campaigns.Hence,this paper presents a Bayesian partial pooling(hierarchical)model for combined analysis of adjacent OC tests.We performed five case studies using OC test data made at a nuclear waste repository research site of Sweden.The results demonstrate that partial pooling of adjacent OC tests indeed allows borrowing of information across adjacent tests,and yields improved stress tensor estimates with reduced uncertainties simultaneously for all individual tests than they are independently analysed as no pooling,particularly for those unreliable no pooling stress estimates.A further model comparison shows that the partial pooling model also gives better predictive performance,and thus confirms that the information borrowed across adjacent OC tests is relevant and effective. 展开更多
关键词 Overcoring stress measurement Uncertainty reduction Partial pooling Bayesian hierarchical model Nuclear waste repository
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An Innovative Finite Element Geometric Modeling of Single-Layer Multi-Bead WAAMed Part
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作者 Xiangman Zhou Jingping Qin +5 位作者 Zichuan Fu Min Wang Youlu Yuan Junjian Fu Haiou Zhang Seyed Reza Elmi Hosseini 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期2383-2401,共19页
Finite element (FE) coupled thermal-mechanical analysis is widely used to predict the deformation and residualstress of wire arc additive manufacturing (WAAM) parts. In this study, an innovative single-layermulti-bead... Finite element (FE) coupled thermal-mechanical analysis is widely used to predict the deformation and residualstress of wire arc additive manufacturing (WAAM) parts. In this study, an innovative single-layermulti-bead profilegeometric modeling method through the isosceles trapezoid function is proposed to build the FE model of theWAAMprocess. Firstly, a straight-line model for overlapping beads based on the parabola function was establishedto calculate the optimal center distance. Then, the isosceles trapezoid-based profile was employed to replace theparabola profiles of the parabola-based overlapping model to establish an innovative isosceles trapezoid-basedmulti-bead overlapping geometric model. The rationality of the isosceles trapezoid-based overlapping model wasconfirmed by comparing the geometric deviation and the heat dissipation performance index of the two overlappingmodels. In addition, the FE-coupled thermal-mechanical analysis, as well as a comparative experiment of thesingle-layer eight-bead deposition process show that the simulation results of the above two models agree with theexperimental results. At the same time, the proposed isosceles trapezoid-based overlappingmodels are all straightlineprofiles, which can be divided into high-quality FE elements. It can improve the modeling efficiency andshorten the simulation calculation time. The innovative modeling method proposed in this study can provide anefficient and high-precision geometricmodelingmethod forWAAMpart FE coupled thermal-mechanical analysis. 展开更多
关键词 WAAM FE coupled thermal-mechanical analysis the isosceles trapezoid-based model residual stress
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Experimental and simulation study on shear stress-induced erythrocyte damage based on vortex oscillator
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作者 Xu Mei Li-Pu Zhao +1 位作者 Lian Hou Ying-Ying Zhong 《Biomedical Engineering Communications》 2024年第1期23-30,共8页
Background:Shear stress-induced erythrocyte damage,namely hemolysis,is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support devices.Computational fluid dyn... Background:Shear stress-induced erythrocyte damage,namely hemolysis,is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support devices.Computational fluid dynamics simulation combined with hemolysis prediction models have been widely used to predict hemolysis.With the development of hemolysis prediction models,the new hemolysis prediction model requires more experimental data to verify.In addition,the difference of in vitro blood-shearing device also affect the accuracy of hemolysis prediction.Methods:To address these problems,a new in vitro blood-shearing device(vortex oscillator)was used to further verify the accuracy of the hemolysis prediction models,and to guide the optimal design of blood-contacting medical devices such as mechanical circulatory support devices.Firstly,the flow field information such as wall stress and velocity of the vortex oscillator under different speeds was analyzed.Secondly,different hemolysis prediction models were used to calculate hemolysis,and the predicted data was compared with the experimental data.Results and Conclusion:In this study,the flow field information inside the vortex oscillator at high rotational speeds was systematically investigated,and the prediction of hemolysis was carried out.The results showed that the predicted data of hemolysis was significantly different from the experimental data,which indicated that it was urgent to establish a standardized in vitro blood-shearing platform to provide a reference for accurate hemolysis prediction. 展开更多
关键词 CFD Hemolysis prediction model Vortex oscillator Shear stress
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Mode-I-crack compression modeling and numerical simulation for evaluation of in-situ stress around advancing coal workfaces
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作者 LIU Wei-qun ZHU Li 《Mining Science and Technology》 EI CAS 2009年第5期569-573,共5页
The relatively high stress probably leads to generation of a fractured or even instable area around a working coalface. Also, the generated weak area often evolves into an easy-infiltrating field of water/gas to great... The relatively high stress probably leads to generation of a fractured or even instable area around a working coalface. Also, the generated weak area often evolves into an easy-infiltrating field of water/gas to greatly increase probability of accident occurrence. To reveal the distribution of high stress around working faces, we put forward the mode-I-crack compression model. In this model, the goaf following a working face is regarded as a mode-I crack in an infinite plate, and the self-gravity of overlaying strata is transformed into an uniform pressure applied normal to the upper edge of the model crack. Solving this problem is based on the Westergaard complex stress function. For comparison, the software RFPA-2D is also employed to simulate the same mining problem, and furthermore extendedly to calculate the stress interference induced by the simultaneous advances of two different working faces. The results show that, the area close to a working face or the goaf tail has the maximum stress, and the stress is distributed directly proportional to the square root of the advance and inversely proportional to the square root of the distance to the working face. The simultaneous advances of two neighboring working faces in different horizontals can lead to extremely high resultant stress in an interference area. 展开更多
关键词 数值模拟 压缩模式 地应力 裂纹 压力分布 评价 煤炭 建模
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