Tissue Doppler Study before and after PCI in Patients with Chronic Stable Angina and Apparent Normal Ventricular Function for Evaluation of Myocardial Function

Background: This study aimed to determine the impact of the percutaneous coronary intervention (PCI) on myocardial function assessed by tissue Doppler echocardiography. Methods: Conventional two-dimensional echocardiography and Myocardial tissue peak velocities were recorded at the lateral, ant.septal, post.septal, posterior, ant. and inferior angles of the mitral annulus as well as at the lateral tricuspid annulus by pulsed-wave tissue Doppler echocardiography before PCI, as well as 1 day and 6 weeks after intervention. Results: Fifty consecutive patients with chronic stable angina and preserved systolic left ventricular function (mean age, 58.3 ± 6.594 years;32 men) undergoing PCI were studied. Conventional echocardiographic revealed no statistically significant difference between pre- and post-PCI (1 day after PCI and 6 weeks after PCI) as regarding trans-mitral and trans-tricuspid flow velocities except as regarding LVEDD, LVESD and LVEF which showed a significant improvement post-PCI. Compared with pre-interventional values, systolic peak velocity and early diastolic velocities improved at all sites (P ≤ 0.05 for each). The most pronounced improvement occurred in the septal area. Similarly, late diastolic velocities improved at all sites (P ≤ 0.05 for each) except at post Wall A’. Also, there was a significant improvement of E’DT & E’/A’ ratio after PCI (P value is significant <0.05 for each) but there was insignificant difference between pre & post PCI for E/E’ (P-value = 0.154). There was a significant improvement in tissue Doppler measures of early, late diastolic function and E’/A’ at the lateral tricuspid annulus after PCI compared with baseline values (P value is significant <0.05) but there was an insignificant change in tissue Doppler measures at the lateral tricuspid annulus of E’DT & E/E’ after PCI (repeated measures ANOVA P-value is >0.05 for each). There were significant reductions in IVRT, IVCT & MPI after PCI (P value is significant <0.05 for each) but there was insignificant change in ET after PCI (P-value = 0.09) at the septal angle of the mitral annulus and the lateral angle of the tricuspid annulus. Conclusions: Tissue Doppler parameters of diastolic and systolic function improve early after successful PCI, and this effect persists to 6 weeks after the intervention that emphasizes its value in the improvement of regional and global LV functions and myocardial contractility.

The Treatment of Essential Hypertension Based on Health Education

Objective: To investigate the treatment effect of essential hypertension based on health education. Methods: A randomized controlled field intervention trial was used in this study, patients with essential hypertension treated in community health services were subjects investigated, and psychological intervention should be carried out based on pharmaceutical services, to evaluate the effect of psychological intervention model based on pharmaceutical care on blood pressure control and overall health improvement in patients with essential hypertension. Results: Before treatment, systolic and diastolic blood pressure had no significant difference between two groups, P > 0.05. After treatment, SBP and DBP in two groups were significantly decreased compared to that before treatment in the same group. After treatment, SBP and DBP in the intervention group were significantly decreased compared with normal group, P 0.05). After treatment, the scores of the physiological health subscale and the total scale of the control group, the scores of each subscale and the total amount of the intervention group were significantly higher than those before the same group, the difference was statistically significant (P Conclusion: Under the background of the new round of medical and health system reforms, this model will help health workers and community residents establish new types of doctor-patient relationship and improve the quality of life of chronic diseases such as hypertension.