期刊文献+
共找到1,127篇文章
< 1 2 57 >
每页显示 20 50 100
Genesis of LCT Pegmatites during Early Paleozoic Orogeny of the North Qinling Orogenic Belt,China:Emplacement Conditions and Structural Control 被引量:1
1
作者 CEN Jubiao FENG Yonggang +6 位作者 LIANG Ting WANG Mengxi ZHANG Jianxin TAN Xijuan ZHANG Jie GAO Jinggang HE Lei 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第5期1226-1243,共18页
The Guanpo pegmatite field in the North Qinling orogenic belt(NQB),China,hosts the most abundant LCT pegmatites.However,their emplacement conditions and structural control remain unexplored.In this contribution,we inv... The Guanpo pegmatite field in the North Qinling orogenic belt(NQB),China,hosts the most abundant LCT pegmatites.However,their emplacement conditions and structural control remain unexplored.In this contribution,we investigated it combining pegmatite orientation measurement with oxygen isotope geothermometry and fluid inclusion study.The orientations of type A1 pegmatites(P_(f)<σ_(2))are predominantly influenced by P-and T-fractures due to simple shearing in Shiziping dextral thrust shear zone during D_(2)deformation,whereas type A2 pegmatites(contemporaneous with D_(4))are governed by hydraulic fractures aligned with S_(0)and S_(0+1)stemming from fluid pressure(P_(f)<σ_(2)).Additionally,type B pegmatites(P_(f)≤σ_(2))exhibit orientations shaped by en echelon extensional fractures in local ductile shear zones(contemporaneous with D_(3)).The albite-quartz oxygen isotope geothermometry and microthermometric analysis of fluid inclusions in elbaites from the latest pegmatites(including types B and A2)suggest that the crystallization P-T for late magmatic and hydrothermal stages are 527.5-559.2℃,320℃,3.1-3.6 kbar and 2.0 kbar,respectively.Our observations along with previous studies suggest that the genesis of the LCT pegmatites was a long-term,multi-stage event during early Paleozoic orogeny(including the collision stage)of the NQB,and was facilitated by various local fractures. 展开更多
关键词 LCT pegmatite emplacement mechanism emplacement condition oxygen isotope geothermometry fluid inclusion North Qinling orogenic belt
下载PDF
A novel method for simulating nuclear explosion with chemical explosion to form an approximate plane wave: Field test and numerical simulation 被引量:1
2
作者 Wei Ming Xiaojie Yang +3 位作者 Yadong Mao Xiang Wang Manchao He Zhigang Tao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2137-2153,共17页
A nuclear explosion in the rock mass medium can produce strong shock waves,seismic shocks,and other destructive effects,which can cause extreme damage to the underground protection infrastructures.With the increase in... A nuclear explosion in the rock mass medium can produce strong shock waves,seismic shocks,and other destructive effects,which can cause extreme damage to the underground protection infrastructures.With the increase in nuclear explosion power,underground protection engineering enabled by explosion-proof impact theory and technology ushered in a new challenge.This paper proposes to simulate nuclear explosion tests with on-site chemical explosion tests in the form of multi-hole explosions.First,the mechanism of using multi-hole simultaneous blasting to simulate a nuclear explosion to generate approximate plane waves was analyzed.The plane pressure curve at the vault of the underground protective tunnel under the action of the multi-hole simultaneous blasting was then obtained using the impact test in the rock mass at the site.According to the peak pressure at the vault plane,it was divided into three regions:the stress superposition region,the superposition region after surface reflection,and the approximate plane stress wave zone.A numerical simulation approach was developed using PFC and FLAC to study the peak particle velocity in the surrounding rock of the underground protective cave under the action of multi-hole blasting.The time-history curves of pressure and peak pressure partition obtained by the on-site multi-hole simultaneous blasting test and numerical simulation were compared and analyzed,to verify the correctness and rationality of the formation of an approximate plane wave in the simulated nuclear explosion.This comparison and analysis also provided a theoretical foundation and some research ideas for the ensuing study on the impact of a nuclear explosion. 展开更多
关键词 Approximate plane wave Multi-hole simultaneous blasting Chemical explosion Nuclear explosion Pressure sensor inclusion
下载PDF
Evolution of nonmetallic inclusions in 80-t 9CrMoCoB large-scale ingots during electroslag remelting process
3
作者 Shengchao Duan Min Joo Lee +3 位作者 Yao Su Wangzhong Mu Dong Soo Kim Joo Hyun Park 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第7期1525-1539,共15页
In combination with theoretical calculations,experiments were conducted to investigate the evolution behavior of nonmetallic inclusions(NMIs)during the manufacture of large-scale heat-resistant steel ingots using 9CrM... In combination with theoretical calculations,experiments were conducted to investigate the evolution behavior of nonmetallic inclusions(NMIs)during the manufacture of large-scale heat-resistant steel ingots using 9CrMoCoB heat-resistant steel and CaF_(2)–CaO–Al_(2)O_(3)–SiO_(2)–B_(2)O_(3)electroslag remelting(ESR)-type slag in an 80-t industrial ESR furnace.The main types of NMI in the consumable electrode comprised pure alumina,a multiphase oxide consisting of an Al_(2)O_(3)core and liquid CaO–Al_(2)O_(3)–SiO_(2)–MnO shell,and M_(23)C_(6)carbides with an MnS core.The Al_(2)O_(3)and MnS inclusions had higher precipitation temperatures than the M_(23)C_(6)-type carbide under equilibrium and nonequilibrium solidification processes.Therefore,inclusions can act as nucleation sites for carbide layer precipitation.The ESR process completely removed the liquid CaO–Al_(2)O_(3)–SiO_(2)–MnO oxide and MnS inclusion with a carbide shell,and only the Al_(2)O_(3)inclusions and Al_(2)O_(3)core with a carbide shell occupied the remelted ingot.The M_(23)C_(6)-type carbides in steel were determined as Cr_(23)C_(6)based on the analysis of transmission electron microscopy results.The substitution of Cr with W,Fe,or/and Mo in the Cr_(23)C_(6)lattice caused slight changes in the lattice parameter of the Cr_(23)C_(6)carbide.Therefore,Cr_(21.34)Fe_(1.66)C_(6),(Cr_(19)W_(4)C_(6),Cr_(18.4)Mo_(4.6)C_(6),and Cr_(16)Fe_(5)Mo_(2)C_(6)can match the fraction pattern of Cr_(23)C_(6)carbide.The Al_(2)O_(3)inclusions in the remelted ingot formed due to the reduction of CaO,SiO_(2),and MnO components in the liquid inclusion.The increased Al content in liquid steel or the higher supersaturation degree of Al_(2)O_(3)precipitation in the remelted ingot than that in the electrode can be attributed to the evaporation of CaF_(2)and the increase in CaO content in the ESR-type slag. 展开更多
关键词 nonmetallic inclusion heat-resistant steel electroslag remelting M_(23)C_(6) carbide MnS inclusion supersaturation degree
下载PDF
Effect of hafnium and molybdenum addition on inclusion characteristics in Co-based dual-phase high-entropy alloys
4
作者 Yong Wang Wei Wang +1 位作者 Joo Hyun Park Wangzhong Mu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第7期1639-1650,共12页
Specific grades of high-entropy alloys(HEAs)can provide opportunities for optimizing properties toward high-temperature applications.In this work,the Co-based HEA with a chemical composition of Co_(47.5)Cr_(30)Fe_(7.5... Specific grades of high-entropy alloys(HEAs)can provide opportunities for optimizing properties toward high-temperature applications.In this work,the Co-based HEA with a chemical composition of Co_(47.5)Cr_(30)Fe_(7.5)Mn_(7.5)Ni_(7.5)(at%)was chosen.The refractory metallic elements hafnium(Hf)and molybdenum(Mo)were added in small amounts(1.5at%)because of their well-known positive effects on high-temperature properties.Inclusion characteristics were comprehensively explored by using a two-dimensional cross-sectional method and extracted by using a three-dimensional electrolytic extraction method.The results revealed that the addition of Hf can reduce Al_(2)O_(3)inclusions and lead to the formation of more stable Hf-rich inclusions as the main phase.Mo addition cannot influence the inclusion type but could influence the inclusion characteristics by affecting the physical parameters of the HEA melt.The calculated coagulation coefficient and collision rate of Al_(2)O_(3)inclusions were higher than those of HfO_(2)inclusions,but the inclusion amount played a larger role in the agglomeration behavior of HfO_(2)and Al_(2)O_(3)inclusions.The impurity level and active elements in HEAs were the crucial factors affecting inclusion formation. 展开更多
关键词 high-entropy alloy non-metallic inclusion AGGLOMERATION thermodynamics ALLOYING
下载PDF
Critical precipitation behavior of MnTe inclusions in resulfurized steels during solidification
5
作者 Xiangyu Xu Lu Zhang +3 位作者 Zifei Wang Qianren Tian Jianxun Fu Xuemin Wang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第8期1849-1857,共9页
Te treatment is an effective method for modifying sulfide inclusions,and MnTe precipitation has an important effect on thermal brittleness and steel corrosion resistance.In most actual industrial applications of Te tr... Te treatment is an effective method for modifying sulfide inclusions,and MnTe precipitation has an important effect on thermal brittleness and steel corrosion resistance.In most actual industrial applications of Te treatment,MnTe precipitation is unexpected.The critical precipitation behavior of MnTe inclusions was investigated through scanning electron microscopy,transmission electron microscopy,machine learning,and first-principles calculation.MnTe preferentially precipitated at the container mouth for sphere-like sulfides and at the interface between MnS grain boundaries and steel matrix for rod-like sulfides.The MnS/MnTe interface was semicoherent.A composition transition zone with a rock-salt structure exhibiting periodic changes existed to maintain the semicoherent interface.The critical precipitation behavior of MnTe inclusions in resulfurized steels involved three stages at varying temperatures.First,Mn(S,Te)precipitated during solidification.Second,MnTe with a rock-salt structure precipitated from Mn(S,Te).Third,MnTe with a hexagonal NiAs structure transformed from the rock-salt structure.The solubility of Te in MnS decreased with decreasing temperature.The critical precipitation behavior of MnTe inclusions in resulfurized steels was related to the MnS precipitation temperature.With the increase in MnS precipitation temperature,the critical Te/S weight ratio decreased.In consideration of the cost-effectiveness of Te addition for industrial production,the Te content in resulfurized steels should be controlled in accordance with MnS precipitation temperature and S content. 展开更多
关键词 resulfurized steels modification of inclusion manganese telluride precipitation
下载PDF
Infrared microthermometry of fluid inclusion in sphalerite:A case study of the Xinqiao deposit in the Middle-Lower Yangtze metallogenic belt
6
作者 Yangyang Wang Yilin Xiao 《中国科学技术大学学报》 CAS CSCD 北大核心 2024年第5期10-21,I0006,共13页
Infrared microthermometry allows direct measurement of fluid inclusions hosted in opaque ore minerals and can provide direct constraints on the evolution of ore-forming fluids.This study presents infrared microthermom... Infrared microthermometry allows direct measurement of fluid inclusions hosted in opaque ore minerals and can provide direct constraints on the evolution of ore-forming fluids.This study presents infrared microthermometry of spherite-hosted fluid inclusions from the Xinqiao deposit in the Middle-Lower Yangtze Metallogenic Belt and sheds new light on the ore genesis of the deposit.Considering that infrared light may lead to non-negligible temperature deviations during microthermometry,some tests were first conducted to ensure the accuracy of the microthermometric measurements.The measurement results indicated that using the lowest light intensity of the microscope and inserting an optical filter were effective in minimizing the possible temperature deviations of infrared microthermometry.All sphalerite-hosted fluid inclusions from the Xinqiao deposit were aqueous.They show homogenization temperature ranging from~200 to 350℃,but have two separate salinity groups(1.0 wt%-10 wt%and 15.1 wt%-19.2 wt%NaCl equivalent).The low-salinity group represents sedimentary exhalative(SEDEX)-associated fluids,whereas the high-salinity group results from modification by later magmatic hydrothermal fluids.Combined with published fluid inclusion data,the four-stage fluid evolution of the Xinqiao deposit was depicted.Furthermore,our data suggest that the Xinqiao deposit was formed by twostage metallogenic events including SEDEX and magmatic-hydrothermal mineralization. 展开更多
关键词 infrared microthermometry fluid inclusion SPHALERITE Xinqiao deposit
下载PDF
Oscillatory Dynamics of a Spherical Solid in a Liquid in an Axisymmetric Variable Cross Section Channel
7
作者 Ivan Karpunin 《Fluid Dynamics & Materials Processing》 EI 2024年第6期1219-1232,共14页
The dynamics of a solid spherical body in an oscillating liquid flow in a vertical axisymmetric channel of variable cross section is experimentally studied.It is shown that the oscillating liquid leads to the generati... The dynamics of a solid spherical body in an oscillating liquid flow in a vertical axisymmetric channel of variable cross section is experimentally studied.It is shown that the oscillating liquid leads to the generation of intense averaged flows in each of the channel segments.The intensity and direction of these flows depend on the dimensionless oscillating frequency.In the region of studied frequencies,the dynamics of the considered body is examined when the primary vortices emerging in the flow occupy the whole region in each segment.For a fixed frequency,an increase in the oscillation amplitude leads to a phase-inclusion holding effect,i.e.,the body occupies a quasi-stationary position in one of the cells of the vertical channel,while oscillating around its average position.It is also shown that the oscillating motion of a liquid column generates an averaged force acting on the body,the magnitude of which depends on the properties of the body and its position in the channel.The quasi-stationary position is determined by the relative density and size of the body,as well as the dimensionless frequency.The behavior of the body as a function of the amplitude and frequency of fluid oscillation and relative size is discussed in detail.Such findings may be used in the future to control the position of a phase inclusion and/or to strengthen mass transfer effects in a channel of variable cross section by means of fluid oscillations. 展开更多
关键词 Phase inclusion axisymmetric channel variable cross section oscillations dimensionless frequency averaged force viscous boundary layer
下载PDF
Study on the effective elastic performance of composites containing decagonal symmetric two-dimensional quasicrystal coatings
8
作者 Yurun WU Lu LI Lianhe LI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第9期1655-1664,共10页
On account of the Mori-Tanaka approach,the effective elastic performance of composites containing decagonal symmetric two-dimensional(2D)quasicrystal(QC)coatings is studied.Explicit expressions for the effective elast... On account of the Mori-Tanaka approach,the effective elastic performance of composites containing decagonal symmetric two-dimensional(2D)quasicrystal(QC)coatings is studied.Explicit expressions for the effective elastic constants of rare-earth QC reinforced magnesium-based composites are provided.Detailed discussion is presented on the effects of the volume fraction of the inclusions,the aspect ratio of the inclusions,the coating thickness,and the coating material parameters on the effective elastic constants of the composites.The results indicate that considering the coating increases the effective elastic constants of the composites to some extent. 展开更多
关键词 Mori-Tanaka approach coated inclusion decagonal symmetric twodimensional(2D)quasicrystal(QC)
下载PDF
Sustainable Water Management Through Pani Panchayats: Stakeholder Perspectives from Angul and Dhenkanal Districts of Odisha
9
作者 Debadatta Das Pallavi Mishra Aishwarya Jojo 《Journal of Water Resource and Protection》 CAS 2024年第10期605-626,共22页
This study evaluates the impact of the Pani Panchayat initiative, a community-based water management program, in the Angul and Dhenkanal districts of Odisha. Utilizing a mixed-methods approach, we gathered qualitative... This study evaluates the impact of the Pani Panchayat initiative, a community-based water management program, in the Angul and Dhenkanal districts of Odisha. Utilizing a mixed-methods approach, we gathered qualitative and quantitative data through structured interviews with diverse stakeholders, focus group discussions, and surveys. The findings indicate that the Angul district exhibited higher levels of fair elections and improved water access due to better canal maintenance, while the Dhenkanal district faced challenges from industrial water usage. The study also examines the potential of technological advancements, such as real-time water monitoring, to enhance governance. By identifying synergies and gaps with existing water policies, the research provides policy recommendations to promote sustainable water management in alignment with the Sustainable Development Goals 2030. 展开更多
关键词 Water Policy Pani Panchayats Impact Assessment Social Inclusion SUSTAINABILITY TECHNOLOGY
下载PDF
Understanding the Link:Emotional Attention in Italian Families and Children’s Social Development
10
作者 Catalda Corvasce Juan Pedro Martínez-Ramón +3 位作者 Francisco Manuel Morales-Rodríguez Lidia Pellicer-García Inmaculada Méndez Cecilia Ruiz-Esteban 《International Journal of Mental Health Promotion》 2024年第9期709-718,共10页
Background:Emotional attention refers to the capacity to recognize and properly respond to one’s and others’emotional states.On another note,family is a primary source of socialization that influences the developmen... Background:Emotional attention refers to the capacity to recognize and properly respond to one’s and others’emotional states.On another note,family is a primary source of socialization that influences the development of various social skills.In another line,adolescence is a complex stage that has been associated with emotional difficulties that could be related to competences such as prosociability and inclusion.It is inferred that through the family context and the attention that is processed,a series of competencies are transmitted to the youngsters,but this relationship is still unclear.For this reason,the study’s purpose was to examine the relationship between the emotional attention of mothers and fathers and the social and prosocial competencies of their children.Methods:To accomplish this,a cross-sectional study and ex post facto design were conducted.The Trait-Meta Mood Scale(TMMS-24)-to assess emotional attention-,the Strengths and Difficulties Questionnaire(SDQ)-to determine the prosociality dimension-,and the Test on Passing Developmental Tasks in Adolescence(TCS-A)-to measure social inclusionwere administered.The participants were N=228 families composed of n=114 mothers/fathers(67.5%females)and n=114 daughters/sons(38.5%females)selected through non-probabilistic sampling using a convenience sample in the Bari region of Italy.A descriptive and inferential analysis-Student’s test and Pearson’s correlation-was performed with the statistic package SPSS version 28(significance level p<0.05).Results:The findings showed that the families possessed an adequate background in emotional attention and that their daughters and sons were also generally well-adjusted in social inclusion and prosociality.It also found certain signs that the prosocial competence of the children could be related to the behavior of their mothers and fathers.Conclusion:In conclusion,social inclusion is related to prosocial behavior,and maybe primarily cultivated within families where parents’emotional self-regulation serves as a model for children although further research is necessary.Comparative studies between different cultures are also proposed. 展开更多
关键词 Educational style coping strategies stress social inclusion emotional attention PROSOCIALITY
下载PDF
Similarity evaluation model for the internal defect detection of strip steel
11
作者 ZHANG Yalin WANG Yaojie WANG Xuemin 《Baosteel Technical Research》 CAS 2024年第1期8-13,共6页
An internal defect meter is an instrument to detect the internal inclusion defects of cold-rolled strip steel.The detection accuracy of the equipment can be evaluated based on the similarity of the multiple detection ... An internal defect meter is an instrument to detect the internal inclusion defects of cold-rolled strip steel.The detection accuracy of the equipment can be evaluated based on the similarity of the multiple detection data obtained for the same steel coil.Based on the cosine similarity model and eigenvalue matrix model,a comprehensive evaluation method to calculate the weighted average of similarity is proposed.Results show that the new method is consistent with and can even replace artificial evaluation to realize the automatic evaluation of strip defect detection results. 展开更多
关键词 internal defect INCLUSION similarity evaluation model REPEATABILITY detection equipment strip steel
下载PDF
Utility of fluid inclusion paleo-temperature in petroleum system modelling:A case study from western offshore,India
12
作者 V.Nandakumar S.Shivapriya Silpa Thankan 《Energy Geoscience》 EI 2024年第2期101-119,共19页
The paleo-temperature(Th)data from fluid inclusions are utilized for thermal history modelling using PetroMod software.Generally,bottom hole temperature(BHT)and vitrinite reflectance(Ro)measurements are widely used in... The paleo-temperature(Th)data from fluid inclusions are utilized for thermal history modelling using PetroMod software.Generally,bottom hole temperature(BHT)and vitrinite reflectance(Ro)measurements are widely used in petroleum system modelling(PSM)in the oil industry for calibration purposes.Th representing the minimum temperature of fluid entrapment estimated from fluid-inclusion study provides extra support to build the thermal models for PSM.Fluid inclusion parameters along with Rock-Eval pyrolysis analysis have been used to predict the maturity of oil in terms of API gravity as well as the maturity of source rocks respectively.Two exploratory wells RV-1(Mumbai Offshore Basin)and KK4C-A-1(Kerala-Konkan Offshore Basin),India were examined and the T_(h)from most of the fluid inclusions of wells RV-1 and KK4C-A-1 fell in the oil window range of 60-140℃suggesting thermal conditions favourable for oil generation in both of the wells.T_(h)of coeval aqueous inclusions along with the Hydrocarbon Fluid inclusions(HCFIs)was used to calibrate PSM.Vital parameters show that source rocks of well RV-1 are mature and that of well KK4C-A-1 are immature.Two sets of PSM are created in terms of generation and expulsion for the dry wells RV-1 and KK4C-A-1 and calibrated each well using fluid inclusion Th and BHT.From the fluid inclusion analysis method,it is evident that hydrocarbon generation happened in both wells and the paleo-temperature indicates that the formations of both wells were subjected to temperatures in the oil window range,even though it was designated as dry wells in the present scenario.The present study highlights the application of fluid inclusion paleo-temperature(Th)during calibration instead of commonly used methods.We could obtain desirable and accurate data output from PSM using T_(h) calibration. 展开更多
关键词 Paleo-temperature(T_(h)) Hydrocarbon fluid inclusion Petroleum system modelling Petroleum generation and expulsion Western offshore basin
下载PDF
Disparities across the CREOG Districts —Variations of Wellness and Inclusivity Efforts in Obstetrics & Gynecology Residency Websites between Two Consecutive Years
13
作者 Taylor Gatson Mark Alvarez +2 位作者 Malik Mays Rachel Coleman Dani Zoorob 《Advances in Reproductive Sciences》 CAS 2024年第1期14-22,共9页
Background: Few studies have focused on the geographic and chronologic assessment of inclusivity and wellness in Obstetrics and Gynecology residency websites across the US. Objective: To identify variations in wellnes... Background: Few studies have focused on the geographic and chronologic assessment of inclusivity and wellness in Obstetrics and Gynecology residency websites across the US. Objective: To identify variations in wellness and inclusivity website depictions across CREOG districts over the past two years. Methods: This is a cross-sectional analysis of the websites of ACGME-accredited OB/GYN residency programs across the United States between April 2022 and April 2023. The assessment was based on a compilation of 22 attributes devised and piloted by 49 medical students. A racially, geographically, and gender-diverse cohort of 11 students performed data collection. Results: A total of 560 websites were analyzed over two years. Wellness efforts remained unchanged in both years (website content, dedicated support personnel, and group activities). In 2023, a reduction in referencing of wellness (22%) and inclusivity (30%) occurred in leadership messaging. However, a 7% increase in the use of inclusive pronouns was noted. A reduction in gender diversity was identified (9% in faculty, 5% in residents), with programs favoring female-only teams. Similarly, a 7% reduction in the number of underrepresented in medicine faculty and residents was noted. A 15% reduction was noted in curricula referencing inclusivity in their mission statement and inclusivity focused research. Conclusions: This study suggests the variations across websites relative to inclusivity and wellness over the past two years. Updated websites may provide an accurate reflection of the offerings of programs and their investment in wellness and inclusivity across the nation. 展开更多
关键词 Diversity GYNECOLOGY Inclusion OBSTETRICS RESIDENCY
下载PDF
Effect of Freeze-Thaw and Urea in Solubility of GPC3-Csub Protein Expressed in Escherichia coli
14
作者 Xuan-Truc Chu-Dao Kim-Tuyen Huynh-Dam +2 位作者 Dang-Thuc Ngo-Luong Quang-Luan Le Thanh-Thao Vo-Nguyen 《Journal of Biosciences and Medicines》 2024年第4期288-297,共10页
Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential ... Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential target molecule for liver cancer treatments because of its over-expression and growth effects on hepatocellular carcinoma (HCC). This study examined the expression and purification of a C-terminal subunit of Glypican-3 protein (GPC3-Csub) due to its application in both diagnosis and therapy for hepatocellular carcinoma. The gene encoding for GPC3-Csub was successfully cloned into plasmid pET28a fused with an affinity tag composed of six consecutive histidine residues (His-tag). Recombinant protein GPC3-Csub was expressed in Escherichia coli BL21 (DE3) in the condition of adding 3% ethanol with IPTG induction. GPC3-Csub was extracted using repeated freeze-thaw cycles with lysozyme, and inclusion bodies were solubilized by 8M Urea, SDS 10% in pH 12. His-tag fused GPC3-Csub proteins allowed it to be purified by affinity chromatography method using the Nickel-nitrilotriacetic acid (Ni-NTA) column. High expression of GPC3-Csub was confirmed by Coomassie staining and western-blot. GPC3-Csub could be isolated with a Ni-NTA column and have a purity of about 90%. 展开更多
关键词 GLYPICAN-3 Affinity Chromatography Inclusion Body Liver Cancer
下载PDF
Blockchain-Based System for Secure and Efficient Cross-Border Remittances: A Potential Alternative to SWIFT
15
作者 Omoshola S. Owolabi Emmanuel Hinneh +6 位作者 Prince C. Uche Nathaniel T. Adeniken Jennifer A. Ohaegbulem Samuel Attakorah Oluwabukola G. Emi-Johnson Chinaza S. Belolisa Harold Nwariaku 《Journal of Software Engineering and Applications》 2024年第8期664-712,共49页
This paper proposes a blockchain-based system as a secure, efficient, and cost-effective alternative to SWIFT for cross-border remittances. The current SWIFT system faces challenges, including slow settlement times, h... This paper proposes a blockchain-based system as a secure, efficient, and cost-effective alternative to SWIFT for cross-border remittances. The current SWIFT system faces challenges, including slow settlement times, high transaction costs, and vulnerability to fraud. Leveraging blockchain technology’s decentralized, transparent, and immutable nature, the proposed system aims to address these limitations. Key features include modular architecture, implementation of microservices, and advanced cryptographic protocols. The system incorporates Proof of Stake consensus with BLS signatures, smart contract execution with dynamic pricing, and a decentralized oracle network for currency conversion. A sophisticated risk-based authentication system utilizes Bayesian networks and machine learning for enhanced security. Mathematical models are presented for critical components, including transaction validation, currency conversion, and regulatory compliance. Simulations demonstrate potential improvements in transaction speed and costs. However, challenges such as regulatory hurdles, user adoption, scalability, and integration with legacy systems must be addressed. The paper provides a comparative analysis between the proposed blockchain system and SWIFT, highlighting advantages in transaction speed, costs, and security. Mitigation strategies are proposed for key challenges. Recommendations are made for further research into scaling solutions, regulatory frameworks, and user-centric designs. The adoption of blockchain-based remittances could significantly impact the financial sector, potentially disrupting traditional models and promoting financial inclusion in underserved markets. However, successful implementation will require collaboration between blockchain innovators, financial institutions, and regulators to create an enabling environment for this transformative system. 展开更多
关键词 INTEROPERABILITY Tokens AML/KYC Compliance Peer-to-Peer Transfers Financial Inclusion
下载PDF
Let’s Talk LGBTQIA+:Strategies and Activities for Teaching Diversity and Inclusion in the Foreign Language Classroom at the College Level
16
作者 Joseph Abraham Levi 《Sino-US English Teaching》 2024年第4期143-170,共28页
In this presentation,the author explores strategies and activities that create a welcoming and nurturing environment for LGBTQIA+foreign language students at the college level in the United States.Indeed,as it is comm... In this presentation,the author explores strategies and activities that create a welcoming and nurturing environment for LGBTQIA+foreign language students at the college level in the United States.Indeed,as it is commonly stated,there is a clear lack of visibility,acceptance/tolerance,and inclusion of LGBTQIA+voices(active and proactive)in foreign language teaching and learning(pedagogical material as well as in-class attitudes and delivery).The reasons for this deficiency are diverse since they cover not only outward discrimination against and/or indifference(passive-aggressive behavior)toward the LGBTQIA+community and its plight,but they also illustrate the sheer,physical inexistence of quality material that can be used to create,present,and foster a welcoming and all-encompassing classroom environment that addresses the diverse spectrum of the LGBTQIA+community while its members try to learn a foreign language and(positively)negotiate how to express their very identity in their new language of choice.Moreover,the scant material that is available in the United States as well as in other Western countries where the LGBTQIA+community by and large is accepted-at least from the legal point of view-hardly represents and covers the subject matter in a satisfactory way.To address this gap,the author will provide some examples in European Portuguese(EP)and Italian(IT),followed by a courtesy translation in English,to illustrate some positive activities and strategies for including LGBTQIA+-related subject matter in the foreign language classroom at the college level.It is his desire that instructors of other foreign languages duplicate in their respective vernaculars the strategies and activities herein presented in order to create a welcoming and safe classroom environment that embraces the LGBTQIA+community as it goes through the enjoyable journey of learning a new language and culture. 展开更多
关键词 DIVERSITY foreign language (trans-)gender INCLUSION LGBTQIA+community
下载PDF
Research on the Constitutional,Historical and Practical Logic of the Chinese Path of Human Rights Development——From the Perspective of the Inclusion of Human Rights Clause in the Constitution
17
作者 FAN Jinxue 《The Journal of Human Rights》 2024年第3期521-547,共27页
The inclusion of the human rights clause in the Chi-nese Constitution is a concern and expression of the spirit of the Con-stitution,which has laid the institutional regulations of the fundamen-tal law for the develop... The inclusion of the human rights clause in the Chi-nese Constitution is a concern and expression of the spirit of the Con-stitution,which has laid the institutional regulations of the fundamen-tal law for the development of human rights in China,provided the principles and value norms of the highest level of effectiveness for the legal protection of human rights,and built a profound constitutional basis for the formation and improvement of the Chinese path of human rights development.The human rights clause is not only a summariza-tion and affirmation of the historical practice of Chinese human rights development under the leadership of the Communist Party of China,but also a new starting point for the development of human rights in China under the leadership of the Communist Party of China.It marks that the development of human rights in China has entered a new era.The Party and the state have finally embarked on a path of human rights development with Chinese characteristics by formulating and implementing the Human Rights Action Plan of China,eliminating ab-solute poverty through the national poverty alleviation campaign,and promoting human rights protection through the rule of law. 展开更多
关键词 inclusion of the human rights clause in the Consti-tution regulations on fundamental rights Chinese path of human rights development historical logic practice logic
下载PDF
A Deep Dive into the Trajectory and Transformation of Fintech in Colombia Through the Case of PTM Colombia-A Secondary Publication
18
作者 Yanni Gabriel GuacanemeÁlvarez Catalina Medina Ardila +1 位作者 Nadeska Gallardo Licháa Otilia Miladys Gil Hoyos 《Proceedings of Business and Economic Studies》 2024年第2期234-244,共11页
This research focuses on analyzing and understanding the evolution and impact of fintech companies in Colombia,using PTM Colombia as a case study,a company that has undergone a significant transformation from its begi... This research focuses on analyzing and understanding the evolution and impact of fintech companies in Colombia,using PTM Colombia as a case study,a company that has undergone a significant transformation from its beginnings as a provider of physical recharges to its current position.as a comprehensive platform for digital financial services.The current research uses a qualitative descriptive approach and emphasizes understanding the perceptions and experiences in the field of Fintech in Colombia,particularly in the case of PTM Colombia.The study revealed that adaptability and customer orientation have been fundamental in the evolution of PTM,allowing the company to expand its range of services by actively listening to the needs of its users and adjusting its strategies accordingly.In addition,an accelerated and diversified growth of Fintech will be observed in Colombia,particularly in sectors such as credit and payments,driven by a constantly advancing technological environment and a regulatory framework that,although it presents challenges,also offers opportunities for financial innovation.This growth has impacted the traditional banking sector,which,instead of being replaced by Fintech,is finding new forms of collaboration and coexistence that benefit both parties and,above all,the end consumer.In conclusion,the study highlights how Fintech in Colombia,represented by cases such as PTM,is redefining the financial landscape through the adoption of advanced technologies,collaboration with traditional banking,and strong customer orientation. 展开更多
关键词 Financial technology Financial inclusion Fintech ecosystem Financial transformation
下载PDF
Experienced Involvement (ExIn) in Social-Psychiatric Care of Germany-Challenges and Chances
19
作者 Susanne Iris Bauer 《Sociology Study》 2024年第3期129-142,共14页
This study explores the integration of Experienced Involvement(ExIn)in social-psychiatric care in Germany,emphasizing both the challenges and opportunities it presents.The European Leonardo da Vinci Project(2005-2007)... This study explores the integration of Experienced Involvement(ExIn)in social-psychiatric care in Germany,emphasizing both the challenges and opportunities it presents.The European Leonardo da Vinci Project(2005-2007)established a curriculum for ExIn,promoting participatory structures in psychiatric services.While peer support is well-established in other European countries,Germany’s experience is still developing.This research uses a mixed methods design,combining quantitative surveys and qualitative interviews,to investigate the professional experiences of ExIn recovery companions and team colleagues in German clinics and support services.The findings reveal numerous benefits:for social-psychiatric services,ExIn enhances service quality,inclusivity,and accessibility;for team colleagues,it fosters reflexivity,hope,and trust,and improves self-care;for service users,it provides empowerment,easy access to support,trust,and hope,and offers credible role models.Despite these benefits,challenges such as stigmatization,lack of recognition,and financial constraints remain and require to be addressed.The study highlights the need and provides implications for a dedicated and inclusive approach to effectively implementing ExIn,ultimately enriching psychiatric care through experiential knowledge and reducing prejudice within mental health services. 展开更多
关键词 peer involvement professionalized peer support social psychiatry INCLUSION education of social works
下载PDF
The Commitment to Promoting a Culture of Equity in Quebec Secondary Schools: Insights from School Stakeholders - A Secondary Publication
20
作者 Corina Borri-Anadon Geneviève Audet Eve Lemaire 《Journal of Contemporary Educational Research》 2024年第3期161-172,共12页
This paper presents the results of a research project on the intercultural climate in schools and the academic success of immigrant students in Quebec.The intercultural climate in eight secondary public schools is doc... This paper presents the results of a research project on the intercultural climate in schools and the academic success of immigrant students in Quebec.The intercultural climate in eight secondary public schools is documented from the standpoint of various school and community stakeholders,students,and parents.More specifically,the paper focuses on the commitment to promoting cultural equity,which is identified through interviews with the targeted stakeholders on exclusionary practices and processes and the practices implemented to counter them.The results identify five areas of vulnerability among certain minoritized groups of students:the transition from welcoming to regular classes for those students learning French,evaluation and support for those experiencing learning or behavioral difficulties,the referral of these students to adult education programs or work-oriented training programs,their participation in extracurricular activities,and their access to special school projects.Nonetheless,some schools do report the introduction of many equity practices in response to the exclusionary ones.However,these initiatives are mostly occasional and voluntary and pertain to interactions between individuals.These findings call for a discussion on the importance of systemic and concerted initiatives towards achieving equity. 展开更多
关键词 Educational inclusion and exclusion Educational inequalities Immigration and ethnicity Canada
下载PDF
上一页 1 2 57 下一页 到第
使用帮助 返回顶部