α-Synuclein causes synaptic pathologies in several neurodegenerative diseases:Parkinson’s disease(PD)is a neurodegenerative disease that impacts the lives of millions of people worldwide.A pathological hallmark o...α-Synuclein causes synaptic pathologies in several neurodegenerative diseases:Parkinson’s disease(PD)is a neurodegenerative disease that impacts the lives of millions of people worldwide.A pathological hallmark of PD,as well as dementia with Lewy bodies(DLB)and several Alzheimer’s disease variants,is the appearanceof intracellular inclusions called Lewy bodies, which contain high levels of aggregated α-synuclein,展开更多
We describe modeling the solid-state dye laser with the microcavity size comparable to light wavelength. Certain symmetry in the allocation of gain material leads to depletion of odd longitudinal modes that, in turn, ...We describe modeling the solid-state dye laser with the microcavity size comparable to light wavelength. Certain symmetry in the allocation of gain material leads to depletion of odd longitudinal modes that, in turn, increases the tunability range of the microlaser. We provide simple physical explanation for the modeling results.展开更多
基金supported by a grant from National Institutes of Health(NINDS/NIA R01NS078165 to JRM)research funds from the Marine Biological Laboratory(to JRM)a research grant from Horizon 2020 Grant No.In Cure EU Joint Programme-JPND(to LB)
文摘α-Synuclein causes synaptic pathologies in several neurodegenerative diseases:Parkinson’s disease(PD)is a neurodegenerative disease that impacts the lives of millions of people worldwide.A pathological hallmark of PD,as well as dementia with Lewy bodies(DLB)and several Alzheimer’s disease variants,is the appearanceof intracellular inclusions called Lewy bodies, which contain high levels of aggregated α-synuclein,
文摘We describe modeling the solid-state dye laser with the microcavity size comparable to light wavelength. Certain symmetry in the allocation of gain material leads to depletion of odd longitudinal modes that, in turn, increases the tunability range of the microlaser. We provide simple physical explanation for the modeling results.