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Free-space measurement-device-independent quantum-key-distribution protocol using decoy states with orbital angular momentum 被引量:18
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作者 王乐 赵生妹 +1 位作者 巩龙延 程维文 《Chinese Physics B》 SCIE EI CAS CSCD 2015年第12期238-245,共8页
In this paper, we propose a measurement-device-independent quantum-key-distribution(MDI-QKD) protocol using orbital angular momentum(OAM) in free space links, named the OAM-MDI-QKD protocol. In the proposed protoc... In this paper, we propose a measurement-device-independent quantum-key-distribution(MDI-QKD) protocol using orbital angular momentum(OAM) in free space links, named the OAM-MDI-QKD protocol. In the proposed protocol,the OAM states of photons, instead of polarization states, are used as the information carriers to avoid the reference frame alignment, the decoy-state is adopted to overcome the security loophole caused by the weak coherent pulse source, and the high efficient OAM-sorter is adopted as the measurement tool for Charlie to obtain the output OAM state. Here, Charlie may be an untrusted third party. The results show that the authorized users, Alice and Bob, could distill a secret key with Charlie's successful measurements, and the key generation performance is slightly better than that of the polarization-based MDI-QKD protocol in the two-dimensional OAM cases. Simultaneously, Alice and Bob can reduce the number of flipping the bits in the secure key distillation. It is indicated that a higher key generation rate performance could be obtained by a high dimensional OAM-MDI-QKD protocol because of the unlimited degree of freedom on OAM states. Moreover,the results show that the key generation rate and the transmission distance will decrease as the growth of the strength of atmospheric turbulence(AT) and the link attenuation. In addition, the decoy states used in the proposed protocol can get a considerable good performance without the need for an ideal source. 展开更多
关键词 measurement-device-independent quantum key distribution orbital angular momentum atmospheric turbulence decoy states
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Security of a practical semi-device-independent quantum key distribution protocol against collective attacks 被引量:1
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作者 汪洋 鲍皖苏 +2 位作者 李宏伟 周淳 李源 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第8期256-260,共5页
Similar to device-independent quantum key distribution (DI-QKD), semi-device-independent quantum key distribu- tion (SDI-QKD) provides secure key distribution without any assumptions about the internal workings of... Similar to device-independent quantum key distribution (DI-QKD), semi-device-independent quantum key distribu- tion (SDI-QKD) provides secure key distribution without any assumptions about the internal workings of the QKD devices. The only assumption is that the dimension of the Hilbert space is bounded. But SDI-QKD can be implemented in a one- way prepare-and-measure configuration without entanglement compared with DI-QKD. We propose a practical SDI-QKD protocol with four preparation states and three measurement bases by considering the maximal violation of dimension witnesses and specific processes of a QKD protocol. Moreover, we prove the security of the SDI-QKD protocol against collective attacks based on the min-entropy and dimension witnesses. We also show a comparison of the secret key rate between the SDI-QKD protocol and the standard QKD. 展开更多
关键词 quantum key distribution semi-device-independent collective attacks secret key rate
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Measurement Device Independent Quantum Key Distribution Based on Orbital Angular Momentum under Parametric Light Source
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作者 Meng Wang Hong Lai Lei Pan 《Computers, Materials & Continua》 SCIE EI 2020年第4期369-387,共19页
On the one hand,existing measurement device independent quantum key distribution(MDI-QKD)protocols have usually adopted single photon source(SPS)and weak coherent photon(WCP),however,these protocols have suffered from... On the one hand,existing measurement device independent quantum key distribution(MDI-QKD)protocols have usually adopted single photon source(SPS)and weak coherent photon(WCP),however,these protocols have suffered from multi-photon problem brought from photon splitter number attacks.On the other hand,the orbital angular momentum(OAM)-MDI-QKD protocol does not need to compare and adjust the reference frame,solving the dependency of the base in the MDI-QKD protocol.Given that,we propose the OAM-MDI-QKD protocol based on the parametric light sources which mainly include single-photon-added-coherent(SPACS)and heralded single-photon sources(HSPS).Due to the stability of OAM and the participation of parametric light sources,the performance of MDI-QKD protocol gradually approaches the ideal situation.Numerical simulation shows that compared with WCP scheme,HSPS and SPACS schemes have increased the maximum secure transmission distance by 30 km and 40 km respectively. 展开更多
关键词 Measurement device independent orbital angular momentum parametric light sources single-photon-added coherent state heralded single-photon sources
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Measurement-device-independent quantum cryptographic conferencing with an untrusted source
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作者 陈瑞柯 鲍皖苏 +4 位作者 汪洋 包海泽 周淳 江木生 李宏伟 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第1期115-124,共10页
Measurement-device-independent quantum cryptographic conferencing(MDI-QCC) protocol puts MDI quantum key distribution(MDI-QKD) forwards to multi-party applications, and suggests a significant framework for practic... Measurement-device-independent quantum cryptographic conferencing(MDI-QCC) protocol puts MDI quantum key distribution(MDI-QKD) forwards to multi-party applications, and suggests a significant framework for practical multi-party quantum communication. In order to mitigate the experimental complexity of MDI-QCC and remove the key assumption(the sources are trusted) in MDI-QCC, we extend the framework of MDI-QKD with an untrusted source to MDI-QCC and give the rigorous security analysis of MDI-QCC with an untrusted source. What is more, in the security analysis we clearly provide a rigorous analytical method for parameters' estimation, which with simple modifications can be applied to not only MDI-QKD with an untrusted source but also arbitrary multi-party communication protocol with an untrusted source. The simulation results show that at reasonable distances the asymptotic key rates for the two cases(with trusted and untrusted sources) almost overlap, which indicates the feasibility of our protocol. 展开更多
关键词 quantum cryptographic conferencing measurement-device-independent quantum key distribution untrusted source
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Performance analysis of continuous-variable measurement-device-independent quantum key distribution under diverse weather conditions
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作者 张淑静 肖晨 +4 位作者 周淳 汪翔 要建姝 张海龙 鲍皖苏 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第2期100-106,共7页
The effects of weather conditions are ubiquitous in practical wireless quantum communication links.Here in this work,the performances of atmospheric continuous-variable measurement-device-independent quantum key distr... The effects of weather conditions are ubiquitous in practical wireless quantum communication links.Here in this work,the performances of atmospheric continuous-variable measurement-device-independent quantum key distribution(CV-MDI-QKD)under diverse weather conditions are analyzed quantitatively.According to the Mie scattering theory and atmospheric CV-MDI-QKD model,we numerically simulate the relationship between performance of CV-MDI-QKD and the rainy and foggy conditions,aiming to get close to the actual combat environment in the future.The results show that both rain and fog will degrade the performance of the CV-MDI-QKD protocol.Under the rainy condition,the larger the raindrop diameter,the more obvious the extinction effect is and the lower the secret key rate accordingly.In addition,we find that the secret key rate decreases with the increase of spot deflection distance and the fluctuation of deflection.Under the foggy condition,the results illustrate that the transmittance decreases with the increase of droplet radius or deflection distance,which eventually yields the decrease in the secret key rate.Besides,in both weather conditions,the increase of transmission distance also leads the secret key rate to deteriorate.Our work can provide a foundation for evaluating the performance evaluation and successfully implementing the atmospheric CV-MDI-QKD in the future field operation environment under different weather conditions. 展开更多
关键词 weather conditions atmospheric continuous-variable measurement-device-independent quantum key distribution(CV-MDI-QKD) performance
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Hong–Ou–Mandel interference with two independent weak coherent states 被引量:3
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作者 陈华 安雪碧 +4 位作者 伍娟 银振强 王双 陈巍 韩正甫 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第2期76-81,共6页
Recently, the Hong-Ou-Mandel (HOM) interference between two independent weak coherent pulses (WCPs) has been paid much attention due to the measurement-device-independent (MDI) quantum key distribution (QKD). ... Recently, the Hong-Ou-Mandel (HOM) interference between two independent weak coherent pulses (WCPs) has been paid much attention due to the measurement-device-independent (MDI) quantum key distribution (QKD). Using classical wave theory, articles reported before show that the visibility of this kind of HOM-type interference is 〈 50%. In this work, we analyze this kind of interference using quantum optics, which reveals more details compared to the wave theory. Analyses confirm the maximum visibility of 50%. And we conclude that the maximum visibility of 50% comes from the two single-photon states in WCPs, without considering the noise. In the experiment, we successfully approach the visibility of 50% by using WCPs splitting from the single pico-second laser source and phase scanning. Since this kind of HOM interference is immune to slow phase fluctuations, both the realized and proposed experiment designs can provide stable ways of high-resolution optical distance detection. 展开更多
关键词 Hong-Ou-Mandel interference weak coherent states measurement-device-independent quantumkey distribution
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Realization of a source-device-independent quantum random number generator secured by nonlocal dispersion cancellation
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作者 Ji-Ning Zhang Ran Yang +7 位作者 Xinhui Li Chang-Wei Sun Yi-Chen Liu Ying Wei Jia-Chen Duan Zhenda Xie Yan-Xiao Gong Shi-Ning Zhu 《Advanced Photonics》 SCIE EI CAS CSCD 2023年第3期108-117,共10页
Quantum random number generators(QRNGs)can provide genuine randomness by exploiting the intrinsic probabilistic nature of quantum mechanics,which play important roles in many applications.However,the true randomness a... Quantum random number generators(QRNGs)can provide genuine randomness by exploiting the intrinsic probabilistic nature of quantum mechanics,which play important roles in many applications.However,the true randomness acquisition could be subjected to attacks from untrusted devices involved or their deviations from the theoretical modeling in real-life implementation.We propose and experimentally demonstrate a source-device-independent QRNG,which enables one to access true random bits with an untrusted source device.The random bits are generated by measuring the arrival time of either photon of the time–energy entangled photon pairs produced from spontaneous parametric downconversion,where the entanglement is testified through the observation of nonlocal dispersion cancellation.In experiment,we extract a generation rate of 4 Mbps by a modified entropic uncertainty relation,which can be improved to gigabits per second by using advanced single-photon detectors.Our approach provides a promising candidate for QRNGs with no characterization or error-prone source devices in practice. 展开更多
关键词 source device independence quantum randomness nonlocal dispersion cancellation time-energy entanglement
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基于BP神经网络的测量设备无关协议参数预测
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作者 周江平 周媛媛 +1 位作者 周学军 李洁琼 《电子科技大学学报》 EI CAS CSCD 北大核心 2024年第4期611-616,共6页
针对传统参数优化方法计算开销大,不能满足实时性要求高、计算量大等应用场景的问题,结合当今主流的机器学习方法,提出了一种改进的基于BP神经网络的参数优化方法,利用本地搜索算法的数据训练网络并对参数进行预测,替代传统的查找算法,... 针对传统参数优化方法计算开销大,不能满足实时性要求高、计算量大等应用场景的问题,结合当今主流的机器学习方法,提出了一种改进的基于BP神经网络的参数优化方法,利用本地搜索算法的数据训练网络并对参数进行预测,替代传统的查找算法,从而获得更好的实时性和更低的计算复杂度,随后与基于随机森林和XGBoost的方法进行了比较。仿真结果表明,BP神经网络预测所得各参数的均方误差数量级为10~(-6)或更小,由该参数计算所得密钥生成率与最优密钥生成率比值的均值为0.998 8,且该应用中BP神经网络相对随机森林和XGBoost具有更好的预测性能。 展开更多
关键词 量子光学 量子密钥分发 BP神经网络 参数优化 测量设备无关
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测量设备无关量子密钥分发中的改进型诱骗态方法
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作者 白峻林 尹华磊 《信息网络安全》 CSCD 北大核心 2024年第6期926-936,共11页
测量设备无关量子密钥分发协议作为量子网络的候选组件之一,消除了探测端的所有漏洞,提升了系统安全性。目前的测量设备无关量子密钥分发协议采用非理想单光子源,并引入了诱骗态方法来提高密钥率。最近,一种整合在诱骗态方法中的数据后... 测量设备无关量子密钥分发协议作为量子网络的候选组件之一,消除了探测端的所有漏洞,提升了系统安全性。目前的测量设备无关量子密钥分发协议采用非理想单光子源,并引入了诱骗态方法来提高密钥率。最近,一种整合在诱骗态方法中的数据后处理方法双扫描法在统计波动方面表现出色。使用诱骗态方法估算单光子对成分时,引入双扫描法能获得更高的密钥率。然而,双扫描法需要耗时的优化过程。在此,文章提出了一种新颖的改进型诱骗态方法,以实现比原始诱骗态方法更好的性能,同时避免了类似双扫描法优化时间的出现。在文章所有的实验参数值模拟中,改进型诱骗态方法均比原始诱骗态方法的密钥率更高;相较于双扫描法,文章所提方法具有速度快、兼容性好的优点。 展开更多
关键词 量子密钥分发 测量设备无关 诱骗态方法
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基于深度学习的第三类独立医用软件产品现状分析和展望
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作者 王士博 陈校云 +1 位作者 李政隆 李庆 《中国数字医学》 2024年第5期83-90,共8页
目的:根据人工智能医疗器械中的第三类深度学习独立软件及其企业的相关情况,分析二者的特征和内在原因,为产业发展提供参考。方法:根据国家药品监督管理局网站和国家企业信用信息公示系统网站的公开信息,整理第三类深度学习独立软件及... 目的:根据人工智能医疗器械中的第三类深度学习独立软件及其企业的相关情况,分析二者的特征和内在原因,为产业发展提供参考。方法:根据国家药品监督管理局网站和国家企业信用信息公示系统网站的公开信息,整理第三类深度学习独立软件及企业信息,并做描述性统计分析。结果:2020年以来,我国有53项第三类深度学习独立软件通过了注册审批,审评数量逐年增加,主要集中在肺和心脏等部位。这些产品分别属于26家企业,在成立时间和地域分布上呈现一定的集中趋势。结论:人工智能医疗器械的健康发展,需持续以临床应用为导向,加强配套政策支持,重视技术和人才的创新作用。 展开更多
关键词 人工智能 医疗器械 深度学习 独立软件
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Measurement-device-independent quantum communication without encryption 被引量:22
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作者 Peng-Hao Niu Zeng-Rong Zhou +3 位作者 Zai-Sheng Lin Yu-Bo Sheng Liu-Guo Yin Gui-Lu Long 《Science Bulletin》 SCIE EI CAS CSCD 2018年第20期1345-1350,共6页
Security in communication is vital in modern life. At present, security is realized by an encryption process in cryptography. It is unbelievable if a secure communication is achievable without encryption. In quantum c... Security in communication is vital in modern life. At present, security is realized by an encryption process in cryptography. It is unbelievable if a secure communication is achievable without encryption. In quantum cryptography, there is a unique form of quantum communication, quantum secure direct communication, where secret information is transmitted directly over a quantum channel. Quantum secure direct communication is drastically distinct from our conventional concept of secure communication, because it does not require key distribution, key storage and ciphertext transmission, and eliminates the encryption procedure completely. Hence it avoids in principle all the security loopholes associated with key and ciphertext in traditional secure communications. For practical implementation, defects always exist in real devices and it may downgrade the security. Among the various device imperfections, those with the measurement devices are the most prominent and serious ones. Here we report a measurementdevice-independent quantum secure direct communication protocol using Einstein-Podolsky-Rosen pairs. This protocol eradicates the security vulnerabilities associated with the measurement device,and greatly enhances the practical security of quantum secure direct communication. In addition to the security advantage, this protocol has an extended communication distance, and a high communication capacity. 展开更多
关键词 QUANTUM secure direct communication Measurement-device-independent QUANTUM dialogue ENCRYPTION Cryptography
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Loss-tolerant measurement device independent quantum key distribution with reference frame misalignment 被引量:1
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作者 王吉鹏 李振华 +6 位作者 孙仲齐 窦天琦 屈文秀 周芬 韩艳鑫 黄雨晴 马海强 《Chinese Optics Letters》 SCIE EI CAS CSCD 2022年第9期61-67,共7页
Reference frame independent and measurement device independent quantum key distribution(RFI-MDI-QKD)has the advantages of being immune to detector side loopholes and misalignment of the reference frame.However,several... Reference frame independent and measurement device independent quantum key distribution(RFI-MDI-QKD)has the advantages of being immune to detector side loopholes and misalignment of the reference frame.However,several former related research works are based on the unrealistic assumption of perfect source preparation.In this paper,we merge a loss-tolerant method into RFI-MDI-QKD to consider source flaws into key rate estimation and compare it with quantum coin method.Based on a reliable experimental scheme,the joint influence of both source flaws and reference frame misalignment is discussed with consideration of the finite-key effect.The results show that the loss-tolerant RFI-MDI-QKD protocol can reach longer key rate performance while considering the existence of source flaws in a real-world implementation. 展开更多
关键词 quantum key distribution source flaw measurement device independence
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Measurement-device-independent quantum key distribution with hyper-encoding 被引量:7
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作者 Zheng-Xia Cui Wei Zhong +1 位作者 Lan Zhou Yu-Bo Sheng 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS CSCD 2019年第11期47-56,共10页
Measurement device-independent quantum key distribution(MDI-QKD) protocols are immune to all possible attacks on the photon detectors during quantum communication, but their key generation rates are low compared with ... Measurement device-independent quantum key distribution(MDI-QKD) protocols are immune to all possible attacks on the photon detectors during quantum communication, but their key generation rates are low compared with those of other QKD schemes.Increasing each individual photon’s channel capacity is an efficient way to increase the key generation rate, and high-dimensional(HD) encoding is a powerful tool for increasing the channel capacity of photons. In this paper, we propose an HD MDI-QKD protocol with qudits hyper-encoded in spatial mode and polarization degrees of freedom(DOFs). In the proposed protocol, keys can be generated using the spatial mode and polarization DOFs simultaneously. The proposed protocol is unconditionally secure,even for weak coherent pulses with decoy states. The proposed MDI-QKD protocol may be useful for future quantum secure communication applications. 展开更多
关键词 QUANTUM communication measurement device-independent QUANTUM key distribution high-dimensional HYPER ENCODING
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Practical Reference-Frame-Independent Measurement-Device-Independent Quantum Key Distribution Systems Against the Worst Relative Rotation of Reference Frames
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作者 张春梅 朱建荣 王琴 《Communications in Theoretical Physics》 SCIE CAS CSCD 2018年第10期379-383,共5页
Reference-frame-independent measurement-device-independent QKD(RFI-MDI-QKD), immune to both the slow unknown drift of reference frames and detector side channel attacks, can generate information-theoretic secure keys.... Reference-frame-independent measurement-device-independent QKD(RFI-MDI-QKD), immune to both the slow unknown drift of reference frames and detector side channel attacks, can generate information-theoretic secure keys. Despite its natural resistance to the slow drift of reference frames, the performance of practical RFI-MDI-QKD systems descends with the increasing drift of reference frames. In this paper, we demonstrate the worst relative rotation of reference frames for practical RFI-MDI-QKD systems, and investigate their performance against the worst-case scenario,both of which are unclear to date. Simulation results show that, practical RFI-MDI-QKD systems can achieve quite good performance even against the worst-case scenario, which clearly demonstrates that it is possible to implement practical MDI-QKD systems with freely drifting reference frames. 展开更多
关键词 分发系统 相对旋转 框架 安全钥匙 信息理论 QKD 飘移 参考书
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Tomographic Approach in Reference-Frame-Independent Measurement-Device-Independent Quantum Key Distribution
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作者 方茜 王超 +3 位作者 韩云光 银振强 陈巍 韩正甫 《Communications in Theoretical Physics》 SCIE CAS CSCD 2016年第11期496-500,共5页
Recently, a novel reference-frame-independent measurement-device-independent quantum key distribution protocol was proposed, which can remove all detector side channels as well as tolerate unknown and slow variance of... Recently, a novel reference-frame-independent measurement-device-independent quantum key distribution protocol was proposed, which can remove all detector side channels as well as tolerate unknown and slow variance of reference frame without active alignment. In this paper, we propose a new tomographic method to estimate the key rate in that protocol. We estimate the key rate using conventional method and tomographic method respectively and compare the two methods by numerical simulation. The numerical simulation results show that tomographic approach is equivalent to the conventional approach, which can be used as an alternative method. 展开更多
关键词 quantum key distribution tomographic reference-frame-independent measurement-deviceindependent
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Fluctuations of Internal Transmittance in Security of Measurement-Device-Independent Quantum Key Distribution with an Untrusted Source
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作者 汪洋 鲍皖苏 +3 位作者 陈瑞柯 周淳 江木生 李宏伟 《Communications in Theoretical Physics》 SCIE CAS CSCD 2017年第8期206-214,共9页
Measurement-device-independent quantum key distribution(MDI-QKD) is immune to detector side channel attacks, which is a crucial security loophole problem in traditional QKD. In order to relax a key assumption that the... Measurement-device-independent quantum key distribution(MDI-QKD) is immune to detector side channel attacks, which is a crucial security loophole problem in traditional QKD. In order to relax a key assumption that the sources are trusted in MDI-QKD, an MDI-QKD protocol with an untrusted source has been proposed. For the security of MDI-QKD with an untrusted source, imperfections in the practical experiment should also be taken into account. In this paper, we analyze the effects of fluctuations of internal transmittance on the security of a decoy-state MDI-QKD protocol with an untrusted source. Our numerical results show that both the secret key rate and the maximum secure transmission distance decrease when taken fluctuations of internal transmittance into consideration. Especially, they are more sensitive when Charlie's mean photon number per pulse is smaller. Our results emphasize that the stability of correlative optical devices is important for practical implementations. 展开更多
关键词 量子密钥分发 测量设备 透射率 信任 波动 量子密钥分配 安全漏洞 平均光子数
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Improving the Performance of Practical Decoy-State Measurement-Device-Independent Quantum Key Distribution with Biased Basis Choice
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作者 张春辉 张春梅 王琴 《Communications in Theoretical Physics》 SCIE CAS CSCD 2018年第9期331-336,共6页
Statistical fluctuations are unavoidable in realistic quantum key distribution (QKD) due to finite-size effect. Based on the four-intensity proposal on measurement-device-independent QKD (MDI-QKD) in [Phys. Rev. A93 (... Statistical fluctuations are unavoidable in realistic quantum key distribution (QKD) due to finite-size effect. Based on the four-intensity proposal on measurement-device-independent QKD (MDI-QKD) in [Phys. Rev. A93 (2016) 042324], we particularly analyze the scenario that only three intensities are used, namely a three-intensity decoy-state MDI-QKD with biased basis choice. After performing full parameter optimization method, simulations results demonstrate that this scenario can obtain distinct enhancement compared with the conventional unbiased threeintensity decoy-state method, e.g. Xu et al.’s [Phys. Rev. A 89 (2014) 052333]. Furthermore, results also show that it works more efficiently by using HSPS than using WCS at longer transmission distance. 展开更多
关键词 状态 基础 偏导 分发 表演 参数优化方法 现实主义 有限尺寸
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标记单光子源下探测器死时间的量子密钥分配 被引量:1
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作者 何业锋 李丽娜 +2 位作者 白倩 陈思昊 强雨薇 《量子电子学报》 CAS CSCD 北大核心 2023年第1期112-119,共8页
考虑到当光子传输速率过高时,量子密钥分配协议在实际应用中会受到探测器死时间的影响,因此对基于标记单光子源协议的安全密钥生成速率和探测器死时间之间的关系进行了探究。首先,在考虑和不考虑探测器死时间这两种情况下,探究了安全密... 考虑到当光子传输速率过高时,量子密钥分配协议在实际应用中会受到探测器死时间的影响,因此对基于标记单光子源协议的安全密钥生成速率和探测器死时间之间的关系进行了探究。首先,在考虑和不考虑探测器死时间这两种情况下,探究了安全密钥生成速率和探测器死时间之间的关系。结果表明:当光子传输速率过高时,探测器死时间的存在的确会影响安全密钥生成速率。进一步分析了不同探测器死时间下安全密钥速率的生成情况。结果表明:探测器死时间的取值越大,得到的安全密钥生成速率就越低,安全密钥生成速率的极限值和探测器死时间τ之间的关系为4.2/τ。 展开更多
关键词 量子光学 量子密钥分配 测量设备无关 标记单光子源 探测器死时间
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一种微流控芯片进样主通道密封装置
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作者 宋满仓 孙宇 刘军山 《微纳电子技术》 CAS 北大核心 2023年第7期1132-1138,共7页
为了满足高密度阵列薄膜微流控芯片在使用过程中,当反应液离心进入微反应腔室后需要进行独立密封的要求,研制了一种机械密封装置。微流控芯片由铝箔盖片、聚丙烯(PP)基片和PP支架组成。通过采用密封装置对微流控芯片进样主通道进行密封... 为了满足高密度阵列薄膜微流控芯片在使用过程中,当反应液离心进入微反应腔室后需要进行独立密封的要求,研制了一种机械密封装置。微流控芯片由铝箔盖片、聚丙烯(PP)基片和PP支架组成。通过采用密封装置对微流控芯片进样主通道进行密封来实现微反应腔室的隔绝密封。通过实验发现,机械密封装置刀头的结构与尺寸会对密封结果产生较大影响。通过增加刀头厚度和使用圆刀头,不仅能大大降低对铝箔盖片的破坏,而且可以避免产生空腔现象。实验结果表明,改进刀头后,铝箔通道底端粗糙度平均值降低了38.7%,通道最低处的铝箔厚度破坏量减少了85%。 展开更多
关键词 微流控芯片 独立密封 密封装置 主通道 刀头
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基于深度学习算法的新一代人工智能独立软件研究的伦理审查重点 被引量:1
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作者 杨千粟 白楠 +1 位作者 曹江 王瑾 《中国医学伦理学》 2023年第2期186-192,共7页
通过整理2017年1月至2021年11月北京市某三甲医院医学伦理委员会审查的新一代人工智能独立软件研究,对其方案设计的完整性、受试者权益保护、数据利用与存储等多个维度涉及的共性问题进行分析归纳,提出伦理委员会在审查此类研究时应特... 通过整理2017年1月至2021年11月北京市某三甲医院医学伦理委员会审查的新一代人工智能独立软件研究,对其方案设计的完整性、受试者权益保护、数据利用与存储等多个维度涉及的共性问题进行分析归纳,提出伦理委员会在审查此类研究时应特别关注其在方案设计、数据安全性、风险评估、跟踪审查等不同于常规临床研究的方面,从而为新一代人工智能独立软件研究的伦理审查提供思路。 展开更多
关键词 深度学习 人工智能 医疗器械 独立软件 伦理审查
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