AIM: To determine the correlation of Adjusted Blood Requirement Index (ABRI) with the 7th day outcome in patients presenting with acute variceal bleeding.METHODS: All patients presenting with acute variceal hemorr...AIM: To determine the correlation of Adjusted Blood Requirement Index (ABRI) with the 7th day outcome in patients presenting with acute variceal bleeding.METHODS: All patients presenting with acute variceal hemorrhage (AVH) were included. Patients with previous band ligation, sclerotherapy, gastrointestinal or hepatic malignancies were excluded. Patients were managed as per standard protocol for AVH with terlipressin and band ligation. ABRI scores were calculated using the formula outcome of alive or expired up to the 7th day after treatment. The correlation between ABRI and mortality was estimated and a receiver operative characteristic (ROC) curve was plotted.RESULTS: A total of 113 patients (76 male; 37 female) were included. On assessment, 18 were in Child's Pugh Class A, 82 in Class B and 13 were in Class C. The median number of blood units transfused ± inter-quartile range was 3.0 ± 2.0. The median ± inter-quartile range for ABRI was 1.3 ± 1.1. The ROC curve of ABRI for expiry showed a significantly large area of 0.848 (P 〈 0.0001; 95% CI: 0.75-0.95). A significant correlation of log transformation of ABRI with an outcome of mortality was present (P 〈 0.0001).展开更多
Based on the characteristics of the complex system, this paper presents a novel method, the monotonic indexes space method, for the effectiveness analysis of the complex system. First, it presents some basic concepts ...Based on the characteristics of the complex system, this paper presents a novel method, the monotonic indexes space method, for the effectiveness analysis of the complex system. First, it presents some basic concepts and assumption such as the monotonic indexes space, monotonic indexes requirement locus, etc. Second, based on the assumption that indexes are monotonic for the requirements, an algorithm is proposed and applied to numerical approximation of monotonic indexes requirement locus with hyperboxes. Third, this paper proposes two algorithms for acquiring intersection of several monotonic indexes requirement locus. Fourth, this paper proposes the monotonic-indexspace based system analysis model such as the system evaluation model, the sensitivity analysis model for indexes. Based on the practical requirement, the concept of fuzzy monotonic indexes requirement locus and the corresponding analysis model are introduced. Finally, this paper applies the above-mentioned models to analyze the effectiveness of a notional anti-stealth-air-defense information system. And the outputs show that the method is promising.展开更多
文摘AIM: To determine the correlation of Adjusted Blood Requirement Index (ABRI) with the 7th day outcome in patients presenting with acute variceal bleeding.METHODS: All patients presenting with acute variceal hemorrhage (AVH) were included. Patients with previous band ligation, sclerotherapy, gastrointestinal or hepatic malignancies were excluded. Patients were managed as per standard protocol for AVH with terlipressin and band ligation. ABRI scores were calculated using the formula outcome of alive or expired up to the 7th day after treatment. The correlation between ABRI and mortality was estimated and a receiver operative characteristic (ROC) curve was plotted.RESULTS: A total of 113 patients (76 male; 37 female) were included. On assessment, 18 were in Child's Pugh Class A, 82 in Class B and 13 were in Class C. The median number of blood units transfused ± inter-quartile range was 3.0 ± 2.0. The median ± inter-quartile range for ABRI was 1.3 ± 1.1. The ROC curve of ABRI for expiry showed a significantly large area of 0.848 (P 〈 0.0001; 95% CI: 0.75-0.95). A significant correlation of log transformation of ABRI with an outcome of mortality was present (P 〈 0.0001).
文摘Based on the characteristics of the complex system, this paper presents a novel method, the monotonic indexes space method, for the effectiveness analysis of the complex system. First, it presents some basic concepts and assumption such as the monotonic indexes space, monotonic indexes requirement locus, etc. Second, based on the assumption that indexes are monotonic for the requirements, an algorithm is proposed and applied to numerical approximation of monotonic indexes requirement locus with hyperboxes. Third, this paper proposes two algorithms for acquiring intersection of several monotonic indexes requirement locus. Fourth, this paper proposes the monotonic-indexspace based system analysis model such as the system evaluation model, the sensitivity analysis model for indexes. Based on the practical requirement, the concept of fuzzy monotonic indexes requirement locus and the corresponding analysis model are introduced. Finally, this paper applies the above-mentioned models to analyze the effectiveness of a notional anti-stealth-air-defense information system. And the outputs show that the method is promising.