基于MARS的岩石抗拉强度预测模型

将无损检测技术与机器学习相结合,通过建立预测模型来快速确定岩石抗拉强度已经成为热门研究方向之一。为了建立预测模型,提出一种基于多元自适应回归样条(MARS)的数据驱动建模技术,用于岩石抗拉强度预测。共收集了80组试验数据,包括施密特回弹数、干密度、点荷载强度指数以及巴西抗拉强度。所有数据被随机分为2个部分,其中70%的数据用于训练模型,剩余30%的数据用于测试模型性能。同时开发了人工神经网络、支持向量机和决策树3种数据驱动模型。选择了4种常用的模型性能评价指标,分别为均方根误差、平均绝对误差、相关系数和决定系数,以此来对所开发模型的预测性能进行比较。结果表明:所开发的智能模型均能够提供较高的预测精度,其中MARS模型性能优于其他3种模型,支持向量机和人工神经网络模型次之,决策树模型相对较差。值得一提的是,MARS模型能够通过方差分析来评估每个变量的相对重要性。研究成果有助于快速确定岩石抗拉强度。

Snow and regolith albedo variations using CRISM data at McMurdo crater,Mars

The cryosphere component provides the most reliable and insightful indications of any planet’s climate dynamics.Using data from the Compact Reconnaissance Imaging Spectrometer for Mars(CRISM),we develop a novel approach to determining the broadband Visible and Near Infrared(VNIR)albedo of the Martian surface.This study focuses on albedo changes in the McMurdo crater,part of Mars’s south polar layer deposits.We compare seasonal and interannual variations of the McMurdo surface albedo before,during,and after the Global Dust Storm(GDS)of Martian Year(MY)34.As the seasons progressed from spring to summer,the mean albedo in MY 32 and 34 plunged by over 40%,by about 35%in MY 33,and by slightly more than 30%in MY 35.Compared interannually,however,mean albedo values within both seasons(spring and summer)exhibited no significant differences in those same years.Notably,interannual albedo difference maps reveal albedo variation of more than±0.3 in certain regions of the crater.Considering only snow-covered pixels,interannual albedo differences suggest that Mars dust had a pervasive impact on Mars’s cryosphere.Variations in maximum and minimum albedo values as high as 0.5 were observed,depending upon differences in the dust levels in Martian snow/ice.The maximum and the minimum snow albedo values were lowest in MY 34,indicating the effect of the intense dust storm event that year.The average snow albedo decreased from 0.45 in MY 32 to 0.40 in MY 33 and to 0.33 in MY 34,and then rose back to 0.40 in MY 35.This trajectory suggests a temporary deposition of dust,partially reversed after the GDS by self-cleaning mechanisms(local aeolian process and CO_(2)sublimation/deposition cycle).

MARS模型在渭河流域参考作物蒸散量计算中的适应性研究

为有效提高气象资料缺失时渭河流域参考作物蒸散量(ET_(0))计算精度,选取流域及附近20个气象站58 a(1960-2017年)逐日气象资料,基于不同气象要素组合,构建16种基于多元自适应回归样条(MARS)的ET_(0)计算模型,并将计算结果与Hargreaves-Samani、Makkink和Irmark-Allen模型进行对比,评价MARS模型在渭河流域的适应性及可移植性。结果表明:MARS模型能很好地甄别ET_(0)与各输入因子间的非线性关系,MARS2(T_(max)、T_(min)、R_(a))计算精度(平均MAE为0.225 mm/d,平均RMSE为0.327 mm/d,平均R2为0.897)能满足应用要求,模型精度随输入气象要素数量的增加而升高;输入因子中引入地球外辐射R_(a),可明显提高MARS模型精度;在输入因子相同时,MARS模型精度高于Hargreaves-Samani、Irmark-Allen和Makkink模型;MARS模型在渭河流域具有很强的泛化能力和可移植性。因此,气象资料缺失时基于MARS建立的ET_(0)计算模型可作为渭河流域ET_(0)计算的推荐模型。

Response of InSight resonance modes to environmental factors on Mars

The InSight(Interior Exploration using Seismic Investigations,Geodesy,and Heat Transport)mission has recorded continuous ambient noise signals with many spectral peaks since its landing in 2018.The majority of these peaks are modes produced by instrumental vibrations and are associated with environmental factors,such as temperature and wind energy fluctuations.Understanding how these modes react under various conditions is crucial because it aids in identifying their origins.In this study,we analyzed the three-component spectra of InSight recordings from sols 184–738 and obtained the horizontal-to-vertical spectral ratio(HVSR,also known as H/V)curves for different time intervals.The primary modes,such as those at 3.3 and 4.1 Hz,exhibited different behaviors,suggesting diverse origins.Some modes were sensitive to low temperature and some were sensitive to high temperature.Additionally,we investigated the influence of wind and temperature on the H/V curve.The peak frequency was mainly affected by temperature,whereas the H/V value was not associated with the temperature or wind only.Characterizing these modes and elucidating their origins are significant for processing signals from InSight and can provide valuable guidance for designing future planetary seismometers.

Opinion consensus incorporating higher-order interactions in individual-collective networks

In the current information society, the dissemination mechanisms and evolution laws of individual or collective opinions and their behaviors are the research hot topics in the field of opinion dynamics. First, in this paper, a two-layer network consisting of an individual-opinion layer and a collective-opinion layer is constructed, and a dissemination model of opinions incorporating higher-order interactions(i.e. OIHOI dissemination model) is proposed. Furthermore, the dynamic equations of opinion dissemination for both individuals and groups are presented. Using Lyapunov's first method,two equilibrium points, including the negative consensus point and positive consensus point, and the dynamic equations obtained for opinion dissemination, are analyzed theoretically. In addition, for individual opinions and collective opinions,some conditions for reaching negative consensus and positive consensus as well as the theoretical expression for the dissemination threshold are put forward. Numerical simulations are carried to verify the feasibility and effectiveness of the proposed theoretical results, as well as the influence of the intra-structure, inter-connections, and higher-order interactions on the dissemination and evolution of individual opinions. The main results are as follows.(i) When the intra-structure of the collective-opinion layer meets certain characteristics, then a negative or positive consensus is easier to reach for individuals.(ii) Both negative consensus and positive consensus perform best in mixed type of inter-connections in the two-layer network.(iii) Higher-order interactions can quickly eliminate differences in individual opinions, thereby enabling individuals to reach consensus faster.

Exploration of cardiac rehabilitation nursing for elderly patients with myocardial infarction based on individualized cardiac rehabilitation

BACKGROUND Myocardial infarction is a high-risk condition prevalent among the elderly population,often leading to adverse clinical manifestations such as reduced cardiopulmonary function,anxiety,and depression post-surgery.Consequently,cardiac rehabilitation holds immense importance in mitigating these complications.AIM To evaluate the effect of individualized cardiac rehabilitation on blood pressure variability(BPV)and baroreflex sensitivity(BRS)in elderly patients with myocardial infarction.METHODS A cohort of 74 elderly patients diagnosed with myocardial infarction and admitted to our hospital between January 2021 and January 2022 were subjected to random selection.Subsequently,all patients were divided into two groups,namely the research group(n=37)and the control group(n=37),utilizing the number table method.The control group received conventional drug treatment and nursing guidance intervention,while the study group underwent individualized cardiac rehabilitation in addition to the interventions received by the control group.All patients were continuously intervened for 12 wk,and the BPV of these two groups in the 1st wk(T0),the 4th wk(T1)and the 12th wk(T2)were compared,BRS,changes in cardiopulmonary function measures,and adverse cardiovascular events.RESULTS Of 24 h diastolic BPV,24 h systolic BPV,carbon dioxide ventilation equivalent slope of the research group were lower than those of the control group at T1 and T2,BRS,peak heart rate and systolic blood pressure product,1 min heart rate recovery were higher than those of the control group,and the incidence of adverse events in the research group was lower than that of the control group,the difference was statistically significant(P<0.05).CONCLUSION In this study,we found that after individualized cardiac rehabilitation in elderly patients with myocardial infarction,BPV and BRS can be effectively improved,cardiac function is significantly enhanced,and a better prognosis is obtained.

Application of patient-derived tumor models in anticancer drug development and individualized medicine

Malignant tumor is the second leading cause of death due to its high incidence, lack of effective treatment and poor prognosis. The evaluation of anticancer drugs used to based on NCI-60 cell line models, but the limited heterogeneity and the divorce from clinical practice of models lead to extremely low success rate of novel anticancer drugs during clinical trials (less than 10%). In recent years, because of the high heterogeneity and human derived tumor matrix, patient-derived tumor models have been gradually applied to the preclinical evaluation of various antitumor drugs, which shows certain advantages in predicting the clinical efficacy of antitumor drugs. Optimize the drug combination through patient-derived tumor models to achieve individualized medicine has gradually become an indispensable strategy in clinical cancer therapy. The current review summarized the development of patient-derived tumor models, characterized the application, advantages and challenges of them in preclinical antitumor drug evaluation and clinical precise medicine, which will provide a scientific basis and novel insights for further basic research, drug development and clinical application.

The Conflict between Individuals and Society in Seize the Day

This paper explores the existential problem in Seize the Day-the conflict between individuals and society in modern society.With a brief introduction of Saul Bellow and the novel,the paper emphasizes the analysis of the conflict and the sources of the conflict.Besides,Saul Bellow uses many rhetorical devices to intensify the conflict.The analysis of these rhetorical devices is beneficial for us to interpret and understand the true meaning of the novel.Through the study of Bellow’s vision and the novel’s metaphorical meaning,we may find an effective solution to the conflict that our human being is involved in,and realize the social values of this novel.

Research Progress on Individualized Treatment of Splenic Aneurysm

Splenic artery aneurysm has a hidden onset and atypical symptoms.There are various diagnostic methods for splenic aneurysms,among which ultrasound is the first choice for aneurysm screening.The diagnostic rate of CTA and DSA reaches 100%.In clinical practice,it is necessary to integrate medical history,symptoms and signs,and multiple imaging results to improve the diagnostic rate.In terms of treatment plans,both intervention and surgical procedures have their strengths,and the application of intervention will be more extensive.We need to adhere to the principle of individualization and choose a reasonable treatment plan for patients.At present,there are many reports on pregnant women with large splenic aneurysms both domestically and internationally.Some scholars believe that large splenic aneurysms may be related to hormonal imbalances during pregnancy,and the specific pathogenic mechanism will become a hot topic in future research.

The Impersonal Theory of Poetry in “Tradition and the Individual Talent” by TS Eliot

Eliot,an important poet,playwright,and literary critic of the nineteenth century in the United States,was the founder of Western modernism.He pioneered the modern poetic criticism.His practice of modernist poetry is the transition from traditionalist poetics to modernist poetics in the 20th century.His famous poetics theory declaration“Tradition and the Individual Talent”is an immortal classic in the field of poetics theory,in which he proposed the concept of“Traditional,”the theory of“Impersonal”poetry,“Objective Correlative,”and so on.All had a profound influence on the 20th-century poetry creation.This paper aims to analyze and discuss the important“Impersonal”theory from the three aspects of its connotation,the relationship between“Personality”and its intertextuality with New Criticism,so as to further understand Eliot’s poetic concepts.

Analysis and Innovative Strategies of Tax Preferential Policies to Promote the Sustainable Development of Small-Scale Individual Businesses

This study conducted an in-depth analysis of the current tax preferential policies for small-scale individual businesses and compared them with similar policies both domestically and internationally,aiming to reveal the advantages and disadvantages of the current system.After examining the impact of these tax preferential policies on the economic status of individual business owners and the broader social economy,this article proposes a set of innovative tax preferential strategies based on theoretical foundations.By developing these innovative strategies and clarifying their implementation paths,the aim is to promote the sustainable and healthy development of small-scale individual businesses,thereby fostering comprehensive socio-economic progress.The conclusion of this study not only summarizes policy recommendations with practical significance but also provides theoretical support for the optimization and innovation of future related systems.

能谱CT结合MARs技术对不同材质义齿伪影去除的临床价值

目的研究能谱CT单能量成像及单能量+多伪影去除系统(MARs)去除义齿周围伪影的临床价值,并比较不同材质义齿对影像质量的影响。方法纳入100例有义齿植入的患者,义齿种类包括镍铬合金(30例)、烤瓷(30例)、胶托+不锈钢托(40例)。在相同CT扫描参数条件下进行能谱成像技术(GSI)扫描,获得混合能量(QC)影像、70~140 keV的单能量影像及单能量+MARs影像。在每例患者义齿伪影最严重层面和邻近无伪影的软组织区域划定2个感兴趣区(ROI):ROI1选取在同层无伪影的头夹肌处;ROI2选取在口腔中部舌部软组织明暗相间伪影区,ROI面积150~200 mm^(2),分别测量噪声(SD)、CT平均值,并计算伪影指数(AI),以SD和AI作为客观评价参数。由2名高年资放射科医师对各组影像质量进行主观评分。结果镍铬合金、烤瓷、胶托+不锈钢托3种材质义齿邻近组织的SD、AI随着管电压的增加而降低,在90 keV及以上时明显低于QC影像;单能量+MARs影像的SD和AI均明显低于同参数单能量影像;随着管电压的增加,口腔软组织的对比度明显降低,在110 keV+MARs时对比度最佳,主观评分最高。镍铬合金、烤瓷、胶托+不锈钢托3种材质义齿最佳成像参数比较,烤瓷的SD和AI最小。结论能谱扫描联合MARs技术能有效减少镍铬合金、烤瓷、胶托+不锈钢托的金属伪影,可作为去除口腔修复体伪影的有效方法。

基于Mars2000的船舶中剖面通用快速优化方法

[目的]船舶中剖面优化具有设计变量多、约束条件复杂的特点。相关研究多采用智能优化算法直接嵌套规范校核软件(如Mars2000)的优化方法,计算量较大。为此,提出基于敏度排序的中剖面快速优化方法。[方法]首先计算各个约束特征量关于各设计变量的敏度,根据敏度信息得到各特征量不满足约束时的设计变量调整次序,并判断各特征量是否只与局部构件相关。优化迭代时,根据当前方案的约束不满足情况,结合敏度信息做变量调整,并进行周期性的敏度更新。最后引入基于坐标轮换法的小范围调整方法进一步提升优化效果。[结果]某油船中剖面算例优化结果表明,所提方法可实现结构减重5.195%。[结论]与直接嵌套Mars2000的智能优化算法相比,本方法在优化效果相当的情况下,计算量仅为前者的5.58%左右,成本优势明显。

Determining the moment of inertia of triaxial Mars with updated global gravity models

The principal moments of inertia(PMIs)with the principal axes are usually taken as the dynamic figure parameters of Mars;they can be deduced from satellite-observed degree-two gravitational potentials in recent global gravity models and from the dynamic ellipticities resulting from precession observations.These PMIs are natural and significant for the geodetic,geophysical,and geodynamic problems of Mars,which are functions of internal density distributions.In this study,a closed and concise formula for determining the PMIs of the entire planet and its core was developed based on the second invariants of gravity and a multipole expansion.We deduced the polar oblateness J^(2)and the equatorial ellipticity J_(22)of Mars to be 1.9566×10^(−3)and 6.3106×10^(−5),respectively.The preferred principal moments of inertia of Mars are A=2.66589×1036 kg·m^(2),B=2.66775×10^(36)kg·m^(2),and C=2.68125×10^(36)kg·m^(2).These values indicate that Mar is slightly triaxial.The equatorial principal moment of inertia of the Martian core is 1.46008×10^(35)kg·m^(2),accounting for~5.47%of the planet’s PMI;this result is critical for investigating the density and size of the core of Mars,and the planet’s free core nutation.

The Mars orbiter magnetometer of Tianwen-1:in-flight performance and first science results

The Mars Orbiter MAGnetometer(MOMAG)is a scientific instrument onboard the orbiter of China’s first mission for Mars—Tianwen-1.Since November 13,2021,it has been recording magnetic field data from the solar wind to the magnetic pile-up region surrounding Mars.Here we present its in-flight performance and first science results,based on its first one and one-half months’data.Comparing these early MOMAG observations to the magnetic field data in the solar wind from NASA’s Mars Atmosphere and Volatile EvolutioN(MAVEN)mission,we report that the MOMAG magnetic field data are at the same level in magnitude,and describe the same magnetic structures with similar variations in three components.We recognize 158 clear bow shock(BS)crossings in these MOMAG data;their locations match well statistically with the modeled average BS.We also identify and compare five pairs of datasets collected when Tianwen-1’s orbiter and the MAVEN probe made simultaneous BS crossings.These BS crossings confirm the global shape of modeled BS,as well as the south-north asymmetry of the Martian BS.Two cases presented in this paper suggest that the BS is probably more dynamic at flank than near the nose.So far,MOMAG performs well,and provides accurate magnetic field vectors.MOMAG is continuously scanning the magnetic field surrounding Mars.Data from MOMAG’s measurements complement data from MAVEN and will undoubt edly advance our understanding of the plasma environment of Mars.

Establishment of organoid models for pancreatic ductal adenocarcinoma and screening of individualized therapy strategy

Background:Patients with pancreatic ductal adenocarcinoma(PDAC)who undergo surgical resection and receive effective chemotherapy have the best chance for longterm survival.Unfortunately,because of the heterogeneity of pancreatic cancer,it is difficult to find a personalized treatment strategy for patients.Organoids are ideal preclinical models for personalized medicine.Therefore,we explore the cultivation conditions and construction methods of PDAC organoid models to screen the individualized therapy strategy.Methods:Fresh PDAC tissues from surgical resection were collected and digested with digestive enzymes;then the tumor cells were embedded in Matrigel with a suitable medium to establish the PDAC organoid models.The genetic stability of the organoids was analyzed using whole exon sequencing;hematoxylin and eosin staining and immunohistochemistry of organoids were performed to analyze their consistency with the pathological morphology of the patient's tumor tissue;After 2 days of organoid culture,we selected four commonly used clinical chemotherapy drugs for single or combined treatment to analyze drug sensitivity.Results:Two cases of PDAC organoid models were successfully established,and the results of their pathological characteristics and exome sequencing were consistent with those of the patient's tumor tissue.Both PDAC organoids showed more sensitivity to gemcitabine and cisplatin,and the combined treatment was more effective than monotherapy.Conclusion:Both organoids better retained the pathological characteristics,genomic stability,and heterogeneity with the original tumor.Individual PDAC organoids exhibited different sensitivities to the same drugs.Thus,this study provided ideal experimental models for screening individualized therapy strategy for patients with PDAC.

Effect of individualized nutrition interventions on clinical outcomes of pregnant women with gestational diabetes mellitus

BACKGROUND Gestational diabetes mellitus(GDM)can lead to excessive pregnancy weight gain(PWG),abnormal glucolipid metabolism,and delayed lactation.Therefore,it is necessary to provide appropriate and effective interventions for pregnant women with GDM.AIM To clarify the effects of individualized nutrition interventions on PWG,glucolipid metabolism,and lactation in pregnant women with GDM.METHODS The study population consisted of 410 pregnant women with GDM who received treatment at the Northern Jiangsu People's Hospital of Jiangsu Provinceand Yangzhou Maternal and Child Health Hospital between December 2020 and December 2022,including 200 who received routine in-terventions[control(Con)group]and 210 who received individualized nutrition interventions[research(Res)group].Data on PWG,glucolipid metabolism[total cholesterol,(TC);triglycerides(TGs);fasting blood glucose(FPG);glycosylated hemoglobin(HbA1c)],lactation time,perinatal complications(cesarean section,premature rupture of membranes,postpartum hemorrhage,and pregnancy-induced hypertension),and neonatal adverse events(premature infants,fetal macrosomia,hypo-glycemia,and respiratory distress syndrome)were collected for comparative analysis.RESULTS The data revealed markedly lower PWG in the Res group vs the Con group,as well as markedly reduced TG,TC,FPG and HbA1c levels after the intervention that were lower than those in the Con group.In addition,obviously earlier lactation and statistically lower incidences of perinatal complications and neonatal adverse events were observed in the Res group.CONCLUSION Individualized nutrition interventions can reduce PWG in pregnant women with GDM,improve their glucolipid metabolism,and promote early lactation,which deserves clinical promotion.

The personal protective equipment(PPE)based on individual combat:A systematic review and trend analysis

With the development of ordnance technology,the survival and safety of individual combatants in hightech warfare are under serious threat,and the Personal Protective Equipment(PPE),as an important guarantee to reduce casualties and maintain military combat effectiveness,is widely developed.This paper systematically reviewed various PPE based on individual combat through literature research and comprehensive discussion,and introduced in detail the latest application progress of PPE in terms of material and technology from three aspects:individual integrated protection system,traditional protection equipment,and intelligent protection equipment,respectively,and discussed in depth the functional improvement and optimization status brought by advanced technology for PPE,focusing on the achievements of individual equipment technology application.Finally,the problems and technical bottlenecks in the development of PPE were analyzed and summarized,and the development trend of PPE were pointed out.The results of the review will provide a forward-looking reference for the current development of individual PPE,and are important guidance for the design and technological innovation of advanced equipment based on the future technological battlefield.

基于MARS和概率规划的离群值检测算法

为提高物联网数据质量,提出一种基于MARS模型和概率规划的多变量离群值检测方法。该方法能够将多个变量结合起来,通过一个模型检测离群值。创建一个多元自适应回归样条模型产生研究化的残差,将残差作为输入,采用概率规划方法,建立基于全贝叶斯推理的一般单变量离群点检测模型。实验结果表明,概率规划模型能检测出更准确的离群点,该模型提供了具有可信区间的概率分布。

Child Neurodevelopment on Mars

This review article aims to gather differences and similarities between planet Mars and planet Earth to determine the necessities for the proper growth and development of the neonatal brain. Factors such as Environmental, Nutritional, Social, Stress, and Education are juxtaposed to understand the difference between pediatric neurodevelopment on both planets. The variation between each factor was analyzed to determine how significant the impact is on neurodevelopment for children. The factors to be discussed were generated based on extensive research on what is most important for proper early neurodevelopment. The five factors are the main categories branched out into subcategories to delve into more detail regarding neurodevelopment. Factors may vary based on the location on each planet, but the best average was cultivated to create a fair evaluation of the differences. Although each factor influences a different part of the brain, each factor (Environmental, Nutritional, Social, Stress, and Education) is equally vital for development anatomy and physiology of the brain.