The South China Sea is a hotspot for regional climate research.Over the past 40 years,considerable improvement has been made in the development and utilization of the islands in the South China Sea,leading to a substa...The South China Sea is a hotspot for regional climate research.Over the past 40 years,considerable improvement has been made in the development and utilization of the islands in the South China Sea,leading to a substantial change in the land-use of the islands.However,research on the impact of human development on the local climate of these islands is lacking.This study analyzed the characteristics of local climate changes on the islands in the South China Sea based on data from the Yongxing Island Observation Station and ERA5 re-analysis.Furthermore,the influence of urbanization on the local climate of the South China Sea islands was explored in this study.The findings revealed that the 10-year average temperature in Yongxing Island increased by approximately 1.11℃from 1961 to 2020,and the contribution of island development and urbanization to the local warming rate over 60 years was approximately 36.2%.The linear increasing trend of the annual hot days from 1961–2020 was approximately 14.84 days per decade.The diurnal temperature range exhibited an increasing trend of 0.05℃per decade,whereas the number of cold days decreased by 1.06days per decade.The rapid increase in construction on Yongxing Island from 2005 to 2021 led to a decrease in observed surface wind speed by 0.32 m s^(-1)per decade.Consequently,the number of days with strong winds decreased,whereas the number of days with weak winds increased.Additionally,relative humidity exhibited a rapid decline from 2001 to 2016 and then rebounded.The study also found substantial differences between the ERA5 re-analysis and observation data,particularly in wind speed and relative humidity,indicating that the use of re-analysis data for climate resource assessment and climate change evaluation on island areas may not be feasible.展开更多
In the present study, the radioreceptor binding method was used to determine the changes of IP3 content in rat brain and dorsal spinal cord of high frequency (100 Hz) electroacupuncture (EA) analgesia and EA tolerance...In the present study, the radioreceptor binding method was used to determine the changes of IP3 content in rat brain and dorsal spinal cord of high frequency (100 Hz) electroacupuncture (EA) analgesia and EA tolerance rat. The control levels of IP3 in rat brain (less cerebellum and cortex) and dorsal spinal cord were 6.3± 0.78 pmol / mg protein and 3.4± 0.60 pmol / mg protein, respectively. The results showed that IP, in brain increased gradually within 45 min after stimulation in EA analgesia rat. Meanwhile, the dorsal spinal cord IP, content decreased significantly 15 min, 30 min after EA stimulation and recovered to control level 45 min after EA stimulation. In EA tolerance rat, IP3 contents markedly increased in brain. And IP3 content in the spinal cord also increased dramatically within 30 min, but decreased rapidly to control level 45 min after EA stimulation. The IP3 level in EA tolerance rat brain and spinal cord was much higher than that in EA analgesia rat (P<0.01). The studies first reported that high frequency (100 Hz) EA may be linked to PI system in its signal transduction pathways.展开更多
Alzheimer’s disease(AD)is a neurodegenerative disorder which is remarkably characterized by pathological hallmarks that include neurofibrillary tangles,neuronal loss extracellular senile plaques containing aggregat...Alzheimer’s disease(AD)is a neurodegenerative disorder which is remarkably characterized by pathological hallmarks that include neurofibrillary tangles,neuronal loss extracellular senile plaques containing aggregated amyloid beta(Aβ),and neurofibrillary tangles composed of the hyperphosphorylated form of the microtubule protein tau.It is the most common form of dementia which is characterized by severe neurodegenerative changes such as loss of neurons and synapses in brain(Kamat et al.,2014).展开更多
With the advent of modern techniques, drugs, and monitoring, general anesthesia has come to be considered an unlikely cause of harm, particularly for healthy patients. While this is largely true, newly emerging clinic...With the advent of modern techniques, drugs, and monitoring, general anesthesia has come to be considered an unlikely cause of harm, particularly for healthy patients. While this is largely true, newly emerging clinical and laboratory studies have sug- gested that exposure to anesthetic agents during early childhood may have long-lasting adverse effects on cognitive function. This concern has been the focus of intense study in the field of anesthesia research. A recent high-profile review by Rappaport et al. (2015) concluded that while many questions remain un- answered, there is strong evidence from laboratory studies that commonly used anesthetics interfere with brain development and that clinical studies suggest a correlation between early childhood exposure to these agents and subsequent effects on learning and cognition. The issue is of sufficient public health importance that a public-private partnership known as Smar- Tots (Strategies for Mitigating Anesthesia-Related Neurotoxicity in Tots) was developed by the FDA to study pediatric anesthetic neurotoxicity. The mechanism of injury underlying this phe- nomenon has yet to be fully elucidated, and there is evidence to suggest that anesthetics may have direct cytotoxic effects on neurons leading to cell death or suppressed neurogenesis (Strat- mann et al., 2010) and that they may interfere with key pro- cesses in neuronal growth and development that underlie brain circuit development (Wagner et al., 2014).展开更多
Dear Sir, I'm Boris Severinsky from the New England College of Optometry, Boston, USA. I write you to present an interesting case of extreme refractive and corneal topography changes induced by daily wearing of Acuv...Dear Sir, I'm Boris Severinsky from the New England College of Optometry, Boston, USA. I write you to present an interesting case of extreme refractive and corneal topography changes induced by daily wearing of Acuvue Advance (Johnson&Johnson, Vision Care) contact lens (CL).展开更多
BACKGROUND: Morphological data have shown that the most important afferent fibers of papillary body come from hippocampal structure.OBJECTIVE: To observe the changes of evoked potential in hippocampus and the signif...BACKGROUND: Morphological data have shown that the most important afferent fibers of papillary body come from hippocampal structure.OBJECTIVE: To observe the changes of evoked potential in hippocampus and the significance after electrostimulation at medial mamillary nucleus. DESIGN: An observational control experiment.SETTING: Department of Physiology, Shenyang Medical College.MATERIALS : Twenty-three male or female Wistar rats, 3-4 months old, weighing 270-350 g, were provided by bhe animal room of Shenyang Medical College [the license number was scxk(Liao)2003-0016]. METHODS: The Wistar rats were anaesthetized by intraperintoneal injection of 20% urethane (1 g/kg), tracheal intubation was also given. The self-made double-pole metal stimulating electrode with the point diameter of 1 mm was inserted into medial mamillary nucleus, the wanted hippocampal guidance spot was found within the rang of the hippocampal region at the same side of tee mamillary body range (CA1-CA4), inserted with same-core guidance electrode, a sole square-wave stimulation of wave wide 0.2 ms stimulated with electrodes at the applied intensity of 7-9 V, the evoked potential was induced through guidance electrodes, and then input to the ATAC-350 data-processing machine for memory showing wave processing, the memory recorded wave recording graph was separately drawn up by the X-Y recording instrument to observe the latency, time procedure and amplitude of the evoked potential in each hippocampal region of the rats and calculate the percentage of the evoked potential in each hippocampal region. Totally 78 guidance spots in hippocampus were recorded, including 30 positive reaction spots and 48 negative ones. MAIN OUTCOME MEASURES: ① Latency, time procedure and amplitude of the evoked potentials in each hippocampal region of rats; ②percentage of the evoked potentials in each hippocampal region; ③ the wave shapes of the evoked potentials in each hippocampal region from different arrangement in the same positive reaction spot. RESULTS :① Of the 30 recorded positive reactions, 9 positive spots fused into the stimulated false marks because of the short latency. The analysis of variance showed that the latency had significant difference (P 〈 0.05), time procedure had highly significant difference (P 〈 0.01 ), but there was no significant difference in the amplitude (P 〉 0.05) among the hippampal regions.② Among the 30 positive spots, the percentage of evoked potential in the hippocampal regions were 34.5% for CA1, 2.0% for CA2, 24.1% for CA3 and 22.4% for CA4. ③ In different levels of the same positive spot, different changes of the evoked potential wave shapes could be observed, and the most obvious change was that of positive wave amplitude. At different positive spots, evoked potentials of positive phase, negative and the double-phase could be observed. CONCLUSION: There are nerve associations between mamillary body and hippocampus, afferent fibers of mamillary body come from hippocampal CA1 region are a little more.展开更多
Various spectroscopic experiments performed on the AIRBUS ZERO G—located in Bordeaux, France—in the years 2002 to 2012 exhibit minute optical reflection/absorption changes (GIACs) as a result of gravitational change...Various spectroscopic experiments performed on the AIRBUS ZERO G—located in Bordeaux, France—in the years 2002 to 2012 exhibit minute optical reflection/absorption changes (GIACs) as a result of gravitational changes between 0 and 1.8 g in various biological species such as maize, oats, Arabidopsis and particularly Phycomyces sporangiophores. During a flight day, the AIRBUS ZERO G conducts 31 parabolas, each of which lasts about three minutes including a period of 22 s of weightlessness. So far, we participated in 11 parabolic flight campaigns including more than 1000 parabolas performing various kinds of experiments. During our campaigns, we observed an unexplainable variability of the measuring signals (GIACs). Using GPS-positioning systems and three dimensional magnetic field sensors, these finally were traced back to the changing earth’s magnetic field associated with the various flight directions. This is the first time that the interaction of gravity and the Earth’ magnetic field in the primary induction process in living system has been observed.展开更多
Trichloroethylene (TCE) is a major pollutant that affects both occupational and general environments. The liver is an important target organ of TCEE. Substantial efforts and remarkable progress into understanding TC...Trichloroethylene (TCE) is a major pollutant that affects both occupational and general environments. The liver is an important target organ of TCEE. Substantial efforts and remarkable progress into understanding TCE cytotoxicity have been made in cultured liver cells. However, the molecular mechanisms by which TCE induces hepatotoxicity are not well understood. SET (also known as protein phosphatase 2A inhibitor, 12PP2A, or template-activating factor-I, TAF-D is a nuclear protein that regulates histone modification, gene transcription, DNA replication, nucleosome assembly,展开更多
The calculation of Ecological Footprint (EF) on the basis of Input-Output model (I-O model) was advanced by Bicknell, and modified and improved hy Ferng who corrected the footprint's aggregation to each sectors. ...The calculation of Ecological Footprint (EF) on the basis of Input-Output model (I-O model) was advanced by Bicknell, and modified and improved hy Ferng who corrected the footprint's aggregation to each sectors. For the lack of sufficient teehnique to deal with the trade between the research areas and the rest of the world, it it necessary to improve this method. And a dynamic analysis of the change of footprint based on I-O model, which could explore the factor impacting the footprint using the ,special advantage of I-O model, ought to be put into practice. After introducing the new method in detail, we calculate and compare the EF and the change of Gansu Province in the northwest of China in 1997 and 2002. The result shows that there was an increase of EF in 2002 caused by final domestic demand. Further; the inerement in EF export was 2.0 × 10^5 ha and 1.6 × 10^6 ha in import. The out-of- region support dropped from 22.6% to 18. 6%. We introduce three factors causing the EF change based on the character of I-O model: the productivity of the resourve which is explained by the change of resource used to obtain one unit output in a sector, the improvement of the economics and the final demand. Finally, we find that the effects of the three factors on the EF change are not identical except the industry sectors and the change of factors in the agriculture and the industry sectors works notably.展开更多
The changes of holographic characteristics of photopolymer induced by temperature are studied experi-mentally. The results show that the exposure sensitivity increases with the increase of temperature. Themaximum diff...The changes of holographic characteristics of photopolymer induced by temperature are studied experi-mentally. The results show that the exposure sensitivity increases with the increase of temperature. Themaximum diffraction efficiency and the final maximum diffraction efficiency increase with the increaseof temperature when the temperature is lower than Tg (glass transition temperature), while they decreasewith the increase of temperature when the temperature is higher than Tg. The effect of the change oftemperature on the saturation refractive index modulation is very weak.展开更多
Subject Code:D05Under support of the National Natural Science Foundation of China,a concerted study by Dr.Huang Gang(黄刚)from the Institute of Atmospheric Physics,Chinese Academy of Sciences,climate scientist Jing-Ji...Subject Code:D05Under support of the National Natural Science Foundation of China,a concerted study by Dr.Huang Gang(黄刚)from the Institute of Atmospheric Physics,Chinese Academy of Sciences,climate scientist Jing-Jia Luo from the Australian Bureau of Meteorology,Dr.Yao Shuailei(姚帅磊)from the Institute展开更多
To assess the relationship between cochlear blood flow (CBF) and auditory function, a procedure of intravital microscopy for observations of the lateral wall vessels of the cochlea coupled with the simultaneous measur...To assess the relationship between cochlear blood flow (CBF) and auditory function, a procedure of intravital microscopy for observations of the lateral wall vessels of the cochlea coupled with the simultaneous measurement of the endocochlear potential (EP) was established in guinea pigs with gradual ischemia of the cochlea. It was found that occlusions of both common carotid arteries and one of the vertebral arteries produced a minor reduction in CBF with no significant alteration in the EP. When intravenous infusion of ATP induced sharp and severe decreases in CBF, the EP varied only slightly from the baseline in some animals while there were no alteration in others. Furthermore, ATP infusions combined with arterial occlusions caused even more severe declines in CBF and a moderate decrease in the EP. The results indicate that not only does the CBF satisfy the basic needs of the processes of cochlear function, but also has a regulatory mechanism to ensure the normal function of the cochlea in the ischemia condition. It was also found that the changes in the stria vascularis vessels induced by decreases in blood pressure (BP) and heart rates were more severe than those of the spiral ligament vessels. This phenomenon indicated that the stria vascularis vessels were more sensitive to decreases of BP and heart rates.展开更多
It has long been known that human activities such as waste fluid disposal and reservoir impoundment may cause earthquakes. Recently, anthropogenic activities to tackle the increasing energy demand and to address clima...It has long been known that human activities such as waste fluid disposal and reservoir impoundment may cause earthquakes. Recently, anthropogenic activities to tackle the increasing energy demand and to address climate change issues are also reported to induce earthquakes. These activities have a common attribute in that fluids are injected and extracted underground and induce spatiotemporal changes of pore pressure and stress, which may cause slip on faults. Induced earthquakes not only pose significant impacts on seismic hazard assessment and preparation, but also raise the question to the society as how to balance the economic needs of resources development and the public's concerns about potential environmental impacts. Here we review the observations of fluid-injection/extraction induced earthquakes, ground deformation associated with these activities, and their physical mechanisms. Furthermore, we discuss the influences of induced earthquakes on seismic hazard models, regulatory policies on these anthropogenic activities, and current development of academic, industrial and government initiatives and collaborations in order to understand this intriguing phenomenon and address associated challenges.展开更多
During the past twenty years,higher education institutions in China have gained enormous rights due to both the streamlining of administration and the decentralization of the government.Their legal status has hence ch...During the past twenty years,higher education institutions in China have gained enormous rights due to both the streamlining of administration and the decentralization of the government.Their legal status has hence changed dramatically.However,the expansion of their rights has also brought about the possibility of higher education institutions profiting by pursuing development.The influence of the market has begun to permeate higher education institutions,and this change has shown some characteristics of induced institutional changes.Accordingly,higher education institutions should be regulated from the perspective of public law,so as to ensure their public nature.展开更多
CRISPR-Cas system has been widely adapted as a platform for genome editing in various eukaryotic organisms, including zebrafish(Cong et al., 2013; Hwang et al., 2013). One of the important applications of CRISPR-Cas...CRISPR-Cas system has been widely adapted as a platform for genome editing in various eukaryotic organisms, including zebrafish(Cong et al., 2013; Hwang et al., 2013). One of the important applications of CRISPR-Cas9 system is to produce double-strand DNA breaks(DSBs) at targeted sites with guide RNA(gRNA).展开更多
The refractive index change and color centers formation in LiYF4 crystal at room temperature are induced by a femtosecond laser irradiation. A mechanism for refractive index change and color centers formation is propo...The refractive index change and color centers formation in LiYF4 crystal at room temperature are induced by a femtosecond laser irradiation. A mechanism for refractive index change and color centers formation is proposed.展开更多
Samarium monosulfide(SmS)is a promising material for creating thermoelectric generators(TEG),gas sensors and strain gauges.Despite the high values of the generated thermo electromotive force(TEMF)(α≈170-350μV/K),me...Samarium monosulfide(SmS)is a promising material for creating thermoelectric generators(TEG),gas sensors and strain gauges.Despite the high values of the generated thermo electromotive force(TEMF)(α≈170-350μV/K),methods for increasing the efficiency of TEGs based on SmS are of considerable interest.One of these methods can be short-term effects of magnetic fields,including pulsed ones,on these materials.The action of a pulsed magnetic field(PMF)leading to an increase in TEMF(U)of SmS ceramic samples is found.Samples that are not subjected to high frequency currents(HFC)annealing show an increase in UT of 44.54%-62.18%(from 11.9 to 17.2-19.3 mV).The conductivity(σ)of the samples is~22 Q/cm and is insensitive to short-term exposure to a PMF.Samples that undergo HFC annealing show an increase in Uof 23.47%-41.31%(from 21.3 to 26.3-30.1 mV)after exposure to a PMF.The conductivity of the samples is~15Ω^(-1)/cm and after a short exposure to the PMF is changing nonmo notonically,with an increase in the overall instability.The difference in the values of Uand a can be explained by presence of an ordered grain structure and a significant amount of the Sm_(2)O_(2)S phase in the samples subjected to HFC annealing.Possible mechanisms of the observed changes are discussed.展开更多
Nd1-xSrxMnO3 (x : 0.3, 0.5) ceramics containing a secondary phase are synthesized by high-energy ball milling and post heat-treatment method. The 4-wire and 2-wire measuring modes are used to investigate the transp...Nd1-xSrxMnO3 (x : 0.3, 0.5) ceramics containing a secondary phase are synthesized by high-energy ball milling and post heat-treatment method. The 4-wire and 2-wire measuring modes are used to investigate the transport character of the grain/phase boundary (inner interface) and electrode-bulk interface (outer interface), respectively, and the results indicate that there is a similar nonlinear I-V behaviour for both of the inner and outer interfaces, however, the electric pulse induced resistance change (EPIR) effect can only be observed at the outer interface.展开更多
基金National Natural Science Foundation of China(U21A6001,42075059)Specific Research Fund of The Innovation Platform for Academicians of Hainan Province(YSPTZX202143)+1 种基金Guangdong Major Project of Basic and Applied Basic Research(2020B0301030004)Science and Technology Project of Guangdong Meteorological Service(GRMC2020M29)。
文摘The South China Sea is a hotspot for regional climate research.Over the past 40 years,considerable improvement has been made in the development and utilization of the islands in the South China Sea,leading to a substantial change in the land-use of the islands.However,research on the impact of human development on the local climate of these islands is lacking.This study analyzed the characteristics of local climate changes on the islands in the South China Sea based on data from the Yongxing Island Observation Station and ERA5 re-analysis.Furthermore,the influence of urbanization on the local climate of the South China Sea islands was explored in this study.The findings revealed that the 10-year average temperature in Yongxing Island increased by approximately 1.11℃from 1961 to 2020,and the contribution of island development and urbanization to the local warming rate over 60 years was approximately 36.2%.The linear increasing trend of the annual hot days from 1961–2020 was approximately 14.84 days per decade.The diurnal temperature range exhibited an increasing trend of 0.05℃per decade,whereas the number of cold days decreased by 1.06days per decade.The rapid increase in construction on Yongxing Island from 2005 to 2021 led to a decrease in observed surface wind speed by 0.32 m s^(-1)per decade.Consequently,the number of days with strong winds decreased,whereas the number of days with weak winds increased.Additionally,relative humidity exhibited a rapid decline from 2001 to 2016 and then rebounded.The study also found substantial differences between the ERA5 re-analysis and observation data,particularly in wind speed and relative humidity,indicating that the use of re-analysis data for climate resource assessment and climate change evaluation on island areas may not be feasible.
文摘In the present study, the radioreceptor binding method was used to determine the changes of IP3 content in rat brain and dorsal spinal cord of high frequency (100 Hz) electroacupuncture (EA) analgesia and EA tolerance rat. The control levels of IP3 in rat brain (less cerebellum and cortex) and dorsal spinal cord were 6.3± 0.78 pmol / mg protein and 3.4± 0.60 pmol / mg protein, respectively. The results showed that IP, in brain increased gradually within 45 min after stimulation in EA analgesia rat. Meanwhile, the dorsal spinal cord IP, content decreased significantly 15 min, 30 min after EA stimulation and recovered to control level 45 min after EA stimulation. In EA tolerance rat, IP3 contents markedly increased in brain. And IP3 content in the spinal cord also increased dramatically within 30 min, but decreased rapidly to control level 45 min after EA stimulation. The IP3 level in EA tolerance rat brain and spinal cord was much higher than that in EA analgesia rat (P<0.01). The studies first reported that high frequency (100 Hz) EA may be linked to PI system in its signal transduction pathways.
基金supported in part by the Council of Scientific and Industrial Research (CSIR), Indiafinancial support to Pradip Kumar Kamat
文摘Alzheimer’s disease(AD)is a neurodegenerative disorder which is remarkably characterized by pathological hallmarks that include neurofibrillary tangles,neuronal loss extracellular senile plaques containing aggregated amyloid beta(Aβ),and neurofibrillary tangles composed of the hyperphosphorylated form of the microtubule protein tau.It is the most common form of dementia which is characterized by severe neurodegenerative changes such as loss of neurons and synapses in brain(Kamat et al.,2014).
文摘With the advent of modern techniques, drugs, and monitoring, general anesthesia has come to be considered an unlikely cause of harm, particularly for healthy patients. While this is largely true, newly emerging clinical and laboratory studies have sug- gested that exposure to anesthetic agents during early childhood may have long-lasting adverse effects on cognitive function. This concern has been the focus of intense study in the field of anesthesia research. A recent high-profile review by Rappaport et al. (2015) concluded that while many questions remain un- answered, there is strong evidence from laboratory studies that commonly used anesthetics interfere with brain development and that clinical studies suggest a correlation between early childhood exposure to these agents and subsequent effects on learning and cognition. The issue is of sufficient public health importance that a public-private partnership known as Smar- Tots (Strategies for Mitigating Anesthesia-Related Neurotoxicity in Tots) was developed by the FDA to study pediatric anesthetic neurotoxicity. The mechanism of injury underlying this phe- nomenon has yet to be fully elucidated, and there is evidence to suggest that anesthetics may have direct cytotoxic effects on neurons leading to cell death or suppressed neurogenesis (Strat- mann et al., 2010) and that they may interfere with key pro- cesses in neuronal growth and development that underlie brain circuit development (Wagner et al., 2014).
文摘Dear Sir, I'm Boris Severinsky from the New England College of Optometry, Boston, USA. I write you to present an interesting case of extreme refractive and corneal topography changes induced by daily wearing of Acuvue Advance (Johnson&Johnson, Vision Care) contact lens (CL).
文摘BACKGROUND: Morphological data have shown that the most important afferent fibers of papillary body come from hippocampal structure.OBJECTIVE: To observe the changes of evoked potential in hippocampus and the significance after electrostimulation at medial mamillary nucleus. DESIGN: An observational control experiment.SETTING: Department of Physiology, Shenyang Medical College.MATERIALS : Twenty-three male or female Wistar rats, 3-4 months old, weighing 270-350 g, were provided by bhe animal room of Shenyang Medical College [the license number was scxk(Liao)2003-0016]. METHODS: The Wistar rats were anaesthetized by intraperintoneal injection of 20% urethane (1 g/kg), tracheal intubation was also given. The self-made double-pole metal stimulating electrode with the point diameter of 1 mm was inserted into medial mamillary nucleus, the wanted hippocampal guidance spot was found within the rang of the hippocampal region at the same side of tee mamillary body range (CA1-CA4), inserted with same-core guidance electrode, a sole square-wave stimulation of wave wide 0.2 ms stimulated with electrodes at the applied intensity of 7-9 V, the evoked potential was induced through guidance electrodes, and then input to the ATAC-350 data-processing machine for memory showing wave processing, the memory recorded wave recording graph was separately drawn up by the X-Y recording instrument to observe the latency, time procedure and amplitude of the evoked potential in each hippocampal region of the rats and calculate the percentage of the evoked potential in each hippocampal region. Totally 78 guidance spots in hippocampus were recorded, including 30 positive reaction spots and 48 negative ones. MAIN OUTCOME MEASURES: ① Latency, time procedure and amplitude of the evoked potentials in each hippocampal region of rats; ②percentage of the evoked potentials in each hippocampal region; ③ the wave shapes of the evoked potentials in each hippocampal region from different arrangement in the same positive reaction spot. RESULTS :① Of the 30 recorded positive reactions, 9 positive spots fused into the stimulated false marks because of the short latency. The analysis of variance showed that the latency had significant difference (P 〈 0.05), time procedure had highly significant difference (P 〈 0.01 ), but there was no significant difference in the amplitude (P 〉 0.05) among the hippampal regions.② Among the 30 positive spots, the percentage of evoked potential in the hippocampal regions were 34.5% for CA1, 2.0% for CA2, 24.1% for CA3 and 22.4% for CA4. ③ In different levels of the same positive spot, different changes of the evoked potential wave shapes could be observed, and the most obvious change was that of positive wave amplitude. At different positive spots, evoked potentials of positive phase, negative and the double-phase could be observed. CONCLUSION: There are nerve associations between mamillary body and hippocampus, afferent fibers of mamillary body come from hippocampal CA1 region are a little more.
基金supported by grant BW 1025 from the DLR/BMBF(Deutsches Zentrum für Luftund Raumfahrt,and Bundesministerium für Bildung und Forschung).
文摘Various spectroscopic experiments performed on the AIRBUS ZERO G—located in Bordeaux, France—in the years 2002 to 2012 exhibit minute optical reflection/absorption changes (GIACs) as a result of gravitational changes between 0 and 1.8 g in various biological species such as maize, oats, Arabidopsis and particularly Phycomyces sporangiophores. During a flight day, the AIRBUS ZERO G conducts 31 parabolas, each of which lasts about three minutes including a period of 22 s of weightlessness. So far, we participated in 11 parabolic flight campaigns including more than 1000 parabolas performing various kinds of experiments. During our campaigns, we observed an unexplainable variability of the measuring signals (GIACs). Using GPS-positioning systems and three dimensional magnetic field sensors, these finally were traced back to the changing earth’s magnetic field associated with the various flight directions. This is the first time that the interaction of gravity and the Earth’ magnetic field in the primary induction process in living system has been observed.
基金supported by NSFC (the National Natural Science Foundation of China) [81273126, 30972454]the Key Project of Guangdong Natural Science Foundation [S2012020010903]+2 种基金the Project of Shenzhen Basic Research Plan [JCYJ20120616 154222545]the Upgrade Scheme of Shenzhen Municipal Key Laboratory [CXB201005260068A]Medical Scientific Research Foundation of Guangdong Province (A2012577)
文摘Trichloroethylene (TCE) is a major pollutant that affects both occupational and general environments. The liver is an important target organ of TCEE. Substantial efforts and remarkable progress into understanding TCE cytotoxicity have been made in cultured liver cells. However, the molecular mechanisms by which TCE induces hepatotoxicity are not well understood. SET (also known as protein phosphatase 2A inhibitor, 12PP2A, or template-activating factor-I, TAF-D is a nuclear protein that regulates histone modification, gene transcription, DNA replication, nucleosome assembly,
基金supported by National Natural Science Foundation of China (Grant No.40671076)CAS (Chinese Academy of Sciences) Action Plan for West Development Project (Grant No.KZCX2-XB2-04-04)
文摘The calculation of Ecological Footprint (EF) on the basis of Input-Output model (I-O model) was advanced by Bicknell, and modified and improved hy Ferng who corrected the footprint's aggregation to each sectors. For the lack of sufficient teehnique to deal with the trade between the research areas and the rest of the world, it it necessary to improve this method. And a dynamic analysis of the change of footprint based on I-O model, which could explore the factor impacting the footprint using the ,special advantage of I-O model, ought to be put into practice. After introducing the new method in detail, we calculate and compare the EF and the change of Gansu Province in the northwest of China in 1997 and 2002. The result shows that there was an increase of EF in 2002 caused by final domestic demand. Further; the inerement in EF export was 2.0 × 10^5 ha and 1.6 × 10^6 ha in import. The out-of- region support dropped from 22.6% to 18. 6%. We introduce three factors causing the EF change based on the character of I-O model: the productivity of the resourve which is explained by the change of resource used to obtain one unit output in a sector, the improvement of the economics and the final demand. Finally, we find that the effects of the three factors on the EF change are not identical except the industry sectors and the change of factors in the agriculture and the industry sectors works notably.
文摘The changes of holographic characteristics of photopolymer induced by temperature are studied experi-mentally. The results show that the exposure sensitivity increases with the increase of temperature. Themaximum diffraction efficiency and the final maximum diffraction efficiency increase with the increaseof temperature when the temperature is lower than Tg (glass transition temperature), while they decreasewith the increase of temperature when the temperature is higher than Tg. The effect of the change oftemperature on the saturation refractive index modulation is very weak.
文摘Subject Code:D05Under support of the National Natural Science Foundation of China,a concerted study by Dr.Huang Gang(黄刚)from the Institute of Atmospheric Physics,Chinese Academy of Sciences,climate scientist Jing-Jia Luo from the Australian Bureau of Meteorology,Dr.Yao Shuailei(姚帅磊)from the Institute
文摘To assess the relationship between cochlear blood flow (CBF) and auditory function, a procedure of intravital microscopy for observations of the lateral wall vessels of the cochlea coupled with the simultaneous measurement of the endocochlear potential (EP) was established in guinea pigs with gradual ischemia of the cochlea. It was found that occlusions of both common carotid arteries and one of the vertebral arteries produced a minor reduction in CBF with no significant alteration in the EP. When intravenous infusion of ATP induced sharp and severe decreases in CBF, the EP varied only slightly from the baseline in some animals while there were no alteration in others. Furthermore, ATP infusions combined with arterial occlusions caused even more severe declines in CBF and a moderate decrease in the EP. The results indicate that not only does the CBF satisfy the basic needs of the processes of cochlear function, but also has a regulatory mechanism to ensure the normal function of the cochlea in the ischemia condition. It was also found that the changes in the stria vascularis vessels induced by decreases in blood pressure (BP) and heart rates were more severe than those of the spiral ligament vessels. This phenomenon indicated that the stria vascularis vessels were more sensitive to decreases of BP and heart rates.
基金supported by the NSFC/RGC Joint Research Scheme sponsored by the Research Grants Council of the Hong Kong Special Administrative Region, China (Grant Nos. N_CUHK418/15, N_CUHK430/16)CUHK-University of Manchester Research Fund (Grant No. 4930227)+4 种基金United States National Science Foundation (Grant No. OCE-1357433)Natural Sciences and Engineering Research Council of Canada (Grant No. STPGP 494141-16)Japan Society for the Promotion of Science (Grant Nos. KAKENHI 2624004, 26280006)National Natural Science Foundation of China (Grant No. 41474033)the Summer School Program of Peking University
文摘It has long been known that human activities such as waste fluid disposal and reservoir impoundment may cause earthquakes. Recently, anthropogenic activities to tackle the increasing energy demand and to address climate change issues are also reported to induce earthquakes. These activities have a common attribute in that fluids are injected and extracted underground and induce spatiotemporal changes of pore pressure and stress, which may cause slip on faults. Induced earthquakes not only pose significant impacts on seismic hazard assessment and preparation, but also raise the question to the society as how to balance the economic needs of resources development and the public's concerns about potential environmental impacts. Here we review the observations of fluid-injection/extraction induced earthquakes, ground deformation associated with these activities, and their physical mechanisms. Furthermore, we discuss the influences of induced earthquakes on seismic hazard models, regulatory policies on these anthropogenic activities, and current development of academic, industrial and government initiatives and collaborations in order to understand this intriguing phenomenon and address associated challenges.
文摘During the past twenty years,higher education institutions in China have gained enormous rights due to both the streamlining of administration and the decentralization of the government.Their legal status has hence changed dramatically.However,the expansion of their rights has also brought about the possibility of higher education institutions profiting by pursuing development.The influence of the market has begun to permeate higher education institutions,and this change has shown some characteristics of induced institutional changes.Accordingly,higher education institutions should be regulated from the perspective of public law,so as to ensure their public nature.
基金supported by the funding from the Science and Technology Program of Shenzhen (JCYJ20150924110425180 and JCYJ20151030170755264)
文摘CRISPR-Cas system has been widely adapted as a platform for genome editing in various eukaryotic organisms, including zebrafish(Cong et al., 2013; Hwang et al., 2013). One of the important applications of CRISPR-Cas9 system is to produce double-strand DNA breaks(DSBs) at targeted sites with guide RNA(gRNA).
文摘The refractive index change and color centers formation in LiYF4 crystal at room temperature are induced by a femtosecond laser irradiation. A mechanism for refractive index change and color centers formation is proposed.
基金Project supported by the Ministry of Science and Higher Education within the State assignment FSRC"Crystallography and Photonics"RAS。
文摘Samarium monosulfide(SmS)is a promising material for creating thermoelectric generators(TEG),gas sensors and strain gauges.Despite the high values of the generated thermo electromotive force(TEMF)(α≈170-350μV/K),methods for increasing the efficiency of TEGs based on SmS are of considerable interest.One of these methods can be short-term effects of magnetic fields,including pulsed ones,on these materials.The action of a pulsed magnetic field(PMF)leading to an increase in TEMF(U)of SmS ceramic samples is found.Samples that are not subjected to high frequency currents(HFC)annealing show an increase in UT of 44.54%-62.18%(from 11.9 to 17.2-19.3 mV).The conductivity(σ)of the samples is~22 Q/cm and is insensitive to short-term exposure to a PMF.Samples that undergo HFC annealing show an increase in Uof 23.47%-41.31%(from 21.3 to 26.3-30.1 mV)after exposure to a PMF.The conductivity of the samples is~15Ω^(-1)/cm and after a short exposure to the PMF is changing nonmo notonically,with an increase in the overall instability.The difference in the values of Uand a can be explained by presence of an ordered grain structure and a significant amount of the Sm_(2)O_(2)S phase in the samples subjected to HFC annealing.Possible mechanisms of the observed changes are discussed.
基金the Project of Hubei Polytechnic University (No.12xjz01R)The Natural Science Foundation of Hubei Province(No.2012FFB01001)the Program of Ministry of Education of China(for New Century Excellent Talents in University, No.NCET-08-0674)for their financial supports
文摘Nd1-xSrxMnO3 (x : 0.3, 0.5) ceramics containing a secondary phase are synthesized by high-energy ball milling and post heat-treatment method. The 4-wire and 2-wire measuring modes are used to investigate the transport character of the grain/phase boundary (inner interface) and electrode-bulk interface (outer interface), respectively, and the results indicate that there is a similar nonlinear I-V behaviour for both of the inner and outer interfaces, however, the electric pulse induced resistance change (EPIR) effect can only be observed at the outer interface.