Clinical Study of Poria-Polyporus Anti-Diarrhea Oral Liquor in Treating Infantile Rotavirus Diarrhea

Objective: To evaluate the efficacy of Poria-Polyporus anti-diarrhea oral liquor (PPAOL) in treating infantile rotavirus diarrhea. Methods: PPAOL was administered to treat 30 cases of infantile rotavirus diarrhea, the effect was observed and compared with that of Smecta. And human rotavirus RNA of patients was detected. Results: The effective rate of the PPAOL group was 83. 33 % and that of Smecta group was 90. 00 %.There was no significant difference between the effect of the two groups in respect of the duration of fever and diarrhea. Human rotavirus RNA showed positive result in 13 patients of PPAOL group and 19 in Smecta group.The duration of virus excretion in both groups was 2 ～7 days, which was much shorter than 9～ 21 days in the previous report. Conclusion: PPAOL is effective in treating infantile rotavirus diarrhea.

双苓止泻口服液治疗小儿轮状病毒性肠炎的临床研究

本研究对双苓止泻口服液（治疗组）与思密达（对照组）治疗小儿轮状病毒性肠炎各３０例的疗效进行了对照观察。治疗组、对照组总有效率分别为８３．３３％、９０．００％，两组比较无显著性差异（Ｐ＞０．０５）；两组退热和止泻时间比较均无显著性差异（Ｐ＞０．０５）。所有病例均检测了粪ＨＲＶ－ＲＮＡ（ＰＡＧＥ法），治疗前治疗组１３例阳性，对照组１９例阳性；终止排毒时间前者为４．４±１．２天（±Ｓ），后者为４．８±１．５天，两者比较无显著性差异（Ｐ＞０．５０）。