Due to increased penetration of renewable energies,DC links and other emerging technologies,power system operation and planning have to cope with various uncertainties and risks.In order to solve the problems of excee...Due to increased penetration of renewable energies,DC links and other emerging technologies,power system operation and planning have to cope with various uncertainties and risks.In order to solve the problems of exceeding short circuit current and multi-infeed DC interaction,a coordinated optimization method is presented in this paper.Firstly,a branch selection strategy is proposed by analyzing the sensitivity relationship between current limiting measures and the impedance matrix.Secondly,the impact of network structure changes on the multi-infeed DC system is derived.Then the coordinated optimization model is established,which considers the cost and effect of current limiting measures,the tightness of network structure and the voltage support capability of AC system to multiple DCs.Finally,the non-dominated sorting genetic algorithm II combining with the branch selection strategy,is used to find the Pareto optimal schemes.Case studies on a planning power system demonstrated the feasibility and speediness of this method.展开更多
HVDC auxiliary power control can significantly improve the transient stability of AC/DC power grid.An HVDC adaptive emergency power support method based on unbalanced power on line estimation is proposed in this paper...HVDC auxiliary power control can significantly improve the transient stability of AC/DC power grid.An HVDC adaptive emergency power support method based on unbalanced power on line estimation is proposed in this paper.By establishing the extended state equation of the system,the on line dynamic estimation of unbalanced power of the system was realized.On this basis,power support was realized based on the principle of the ladder increment.The optimal DC was selected by the power support factor,and the emergency power support controller was installed on the DC.This emergency power support method can realize dynamic optimal power support with minimized control cost.The three infeed HVDC system was built on PSCAD.The simulation results show the effectiveness of the proposed method.展开更多
Intestinal alkaline phosphatase(IAP) plays an essential role in intestinal homeostasis and health through interactions with the resident microbiota, diet and the gut. IAP's role in the intestine is to dephosphoryl...Intestinal alkaline phosphatase(IAP) plays an essential role in intestinal homeostasis and health through interactions with the resident microbiota, diet and the gut. IAP's role in the intestine is to dephosphorylate toxic microbial ligands such as lipopolysaccharides, unmethylated cytosine-guanosine dinucleotides and flagellin as well as extracellular nucleotides such as uridine diphosphate. IAP's ability to detoxify these ligands is essential in protecting the host from sepsis during acute inflammation and chronic inflammatory conditions such as inflammatory bowel disease. Also important in these complications is IAP's ability to regulate the microbial ecosystem by forming a complex relationship between microbiota, diet and the intestinal mucosal surface. Evidence reveals that diet alters IAP expression and activity and this in turn can influence the gut microbiota and homeostasis. IAP's ability to maintain a healthygastrointestinal tract has accelerated research on its potential use as a therapeutic agent against a multitude of diseases.Exogenous IAP has been shown to have beneficial effects when administered during ulcerative colitis,coronary bypass surgery and sepsis.There are currently a handful of human clinical trials underway investigating the effects of exogenous IAP during sepsis,rheumatoid arthritis and heart surgery.In light of these findings IAP has been marked as a novel agent to help treat a variety of other inflammatory and infectious diseases.The purpose of this review is to highlight the essential characteristics of IAP in protection and maintenance of intestinal homeostasis while addressing the intricate interplay between IAP,diet,microbiota and the intestinal epithelium.展开更多
Adenomyosis (AD) refers to the endometrium (including glands and stroma) into myometrium gr owth of pathological changes, with the delay of women's childbea ring age, the pa ti ents with AD-associated infertility ...Adenomyosis (AD) refers to the endometrium (including glands and stroma) into myometrium gr owth of pathological changes, with the delay of women's childbea ring age, the pa ti ents with AD-associated infertility increased significantly. Although scholars disagreed about the effect of AD on infertility, more and more evidence showed that AD was closely related to the str uct ural and func ti onal defects of the eutopic endomet rium and myomet rial junc tional zone (MJZ), which may lead to embryo implantation failure and infertility. With the rapid development of imaging technology, the accuracy of diagnose AD has been enhanced, more and more infertility patients were diagnosed with AD. At the same time, a series of pathogenic hypothesis have been proposed to explain the relationship between AD. In addition, AD may influence the patient's reproductive function by affecting sperm transport, embryo implantation, altering uterine peristalsis, influencing the structure and function of endometrium, and changing the intrauterine environment. At present, the treatment of AD-associated infertility is similar to the treatment of AD. The commonly used treatment methods include drug therapy, conservative operative treatment, drug combination surgery, and Chinese medicine treatment and so on. The clinical and experimental studies of AD complicated with infertility and its possible pathogenesis and treatment in recent years are reviewed in this article.展开更多
基金This work was supported by State Grid Corporation of China,Major Projects on Planning and Operation Control of Large Scale Grid under Grant SGCC-MPLG020-2012.
文摘Due to increased penetration of renewable energies,DC links and other emerging technologies,power system operation and planning have to cope with various uncertainties and risks.In order to solve the problems of exceeding short circuit current and multi-infeed DC interaction,a coordinated optimization method is presented in this paper.Firstly,a branch selection strategy is proposed by analyzing the sensitivity relationship between current limiting measures and the impedance matrix.Secondly,the impact of network structure changes on the multi-infeed DC system is derived.Then the coordinated optimization model is established,which considers the cost and effect of current limiting measures,the tightness of network structure and the voltage support capability of AC system to multiple DCs.Finally,the non-dominated sorting genetic algorithm II combining with the branch selection strategy,is used to find the Pareto optimal schemes.Case studies on a planning power system demonstrated the feasibility and speediness of this method.
基金the National Natural Science Foundation of China(Grant No.51607158)the Key Scientific Technological Project in Henan Province(Grant No.192102210075)。
文摘HVDC auxiliary power control can significantly improve the transient stability of AC/DC power grid.An HVDC adaptive emergency power support method based on unbalanced power on line estimation is proposed in this paper.By establishing the extended state equation of the system,the on line dynamic estimation of unbalanced power of the system was realized.On this basis,power support was realized based on the principle of the ladder increment.The optimal DC was selected by the power support factor,and the emergency power support controller was installed on the DC.This emergency power support method can realize dynamic optimal power support with minimized control cost.The three infeed HVDC system was built on PSCAD.The simulation results show the effectiveness of the proposed method.
基金Supported by Crohn’s and Colitis Foundation of Canada,No.11883 1486 RR 0001Natural Science and Engineering Re-search Council and the Intestinal Diseases Education Awareness Society,No.86435 5557 RR0001
文摘Intestinal alkaline phosphatase(IAP) plays an essential role in intestinal homeostasis and health through interactions with the resident microbiota, diet and the gut. IAP's role in the intestine is to dephosphorylate toxic microbial ligands such as lipopolysaccharides, unmethylated cytosine-guanosine dinucleotides and flagellin as well as extracellular nucleotides such as uridine diphosphate. IAP's ability to detoxify these ligands is essential in protecting the host from sepsis during acute inflammation and chronic inflammatory conditions such as inflammatory bowel disease. Also important in these complications is IAP's ability to regulate the microbial ecosystem by forming a complex relationship between microbiota, diet and the intestinal mucosal surface. Evidence reveals that diet alters IAP expression and activity and this in turn can influence the gut microbiota and homeostasis. IAP's ability to maintain a healthygastrointestinal tract has accelerated research on its potential use as a therapeutic agent against a multitude of diseases.Exogenous IAP has been shown to have beneficial effects when administered during ulcerative colitis,coronary bypass surgery and sepsis.There are currently a handful of human clinical trials underway investigating the effects of exogenous IAP during sepsis,rheumatoid arthritis and heart surgery.In light of these findings IAP has been marked as a novel agent to help treat a variety of other inflammatory and infectious diseases.The purpose of this review is to highlight the essential characteristics of IAP in protection and maintenance of intestinal homeostasis while addressing the intricate interplay between IAP,diet,microbiota and the intestinal epithelium.
文摘Adenomyosis (AD) refers to the endometrium (including glands and stroma) into myometrium gr owth of pathological changes, with the delay of women's childbea ring age, the pa ti ents with AD-associated infertility increased significantly. Although scholars disagreed about the effect of AD on infertility, more and more evidence showed that AD was closely related to the str uct ural and func ti onal defects of the eutopic endomet rium and myomet rial junc tional zone (MJZ), which may lead to embryo implantation failure and infertility. With the rapid development of imaging technology, the accuracy of diagnose AD has been enhanced, more and more infertility patients were diagnosed with AD. At the same time, a series of pathogenic hypothesis have been proposed to explain the relationship between AD. In addition, AD may influence the patient's reproductive function by affecting sperm transport, embryo implantation, altering uterine peristalsis, influencing the structure and function of endometrium, and changing the intrauterine environment. At present, the treatment of AD-associated infertility is similar to the treatment of AD. The commonly used treatment methods include drug therapy, conservative operative treatment, drug combination surgery, and Chinese medicine treatment and so on. The clinical and experimental studies of AD complicated with infertility and its possible pathogenesis and treatment in recent years are reviewed in this article.
