Objective: To evaluate the effect of domestic human menopausal gonadotropin (HMG) in treat-ment of anovulatory infertility Method:Sequential regimen with HMG and hCG were used in 110 cases with a total of 198 treat-me...Objective: To evaluate the effect of domestic human menopausal gonadotropin (HMG) in treat-ment of anovulatory infertility Method:Sequential regimen with HMG and hCG were used in 110 cases with a total of 198 treat-ment cycles, average 1. 8 cycles per patent and 33. 8 ampules of HMG per cycle. The dosage of hCG for induction of ovulation was divided into three groups: 10 000IU, 15 000IU, and 25 000IU. Methods used for monitoring ovulation were BBT,cervical mucus score,ultrasonography and hormone assays.Results: The ovulation rate per case was 99. 1 % and percycle was 94%; the pregnancy rate per case was 50% (37% for primary amenorrhea and 58% for secondary amenorrhea) and per cycle was 27%.Among the 55 pregnant women 44 delivered and 11 aborted. There were 8 twin pregnancies The compli-caton of ovarian hyperstimulation syndrome (OHSS) was encountered in 38 cases (34% ): mild in 12 (10.9%), moderate in 21 (19.0%) and severe in 5 (4. 5%).Conclusion:Domestic HMG showed satisfactory results in the treatment of hypogonadotrophic a-menorrhea or anovulatory infertility.展开更多
文摘Objective: To evaluate the effect of domestic human menopausal gonadotropin (HMG) in treat-ment of anovulatory infertility Method:Sequential regimen with HMG and hCG were used in 110 cases with a total of 198 treat-ment cycles, average 1. 8 cycles per patent and 33. 8 ampules of HMG per cycle. The dosage of hCG for induction of ovulation was divided into three groups: 10 000IU, 15 000IU, and 25 000IU. Methods used for monitoring ovulation were BBT,cervical mucus score,ultrasonography and hormone assays.Results: The ovulation rate per case was 99. 1 % and percycle was 94%; the pregnancy rate per case was 50% (37% for primary amenorrhea and 58% for secondary amenorrhea) and per cycle was 27%.Among the 55 pregnant women 44 delivered and 11 aborted. There were 8 twin pregnancies The compli-caton of ovarian hyperstimulation syndrome (OHSS) was encountered in 38 cases (34% ): mild in 12 (10.9%), moderate in 21 (19.0%) and severe in 5 (4. 5%).Conclusion:Domestic HMG showed satisfactory results in the treatment of hypogonadotrophic a-menorrhea or anovulatory infertility.
