Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders

Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in mice.The cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)proteins.The cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).

Quantum information processing with nitrogen–vacancy centers in diamond

Nitrogen-vacancy （NV） center in diamond is one of the most promising candidates to implement room temperature quantum computing. In this review, we briefly discuss the working principles and recent experimental progresses of this spin qubit. These results focus on understanding and prolonging center spin coherence, steering and probing spin states with dedicated quantum control techniques, and exploiting the quantum nature of these multi-spin systems, such as superposition and entanglement, to demonstrate the superiority of quantum information processing. Those techniques also stimulate the fast development of NV-based quantum sensing, which is an interdisciplinary field with great potential applications.

Single-channel vector magnetic information detection method based on diamond NV color center

A method of detecting the single channel triaxial magnetic field information based on diamond nitrogen-vacancy(NV)color center is introduced.Firstly,the incident angle of the bias magnetic field which can achieve the equal frequency difference optically-detected magnetic resonance(ODMR)spectrum of diamond NV color center is calculated theoretically,and the triaxial magnetic information solution model is also constructed.Secondly,the microwave time-controlled circuit module is designed to generate equal timing and equal frequency difference microwave pulse signals in one channel.Combining with the optical detection magnetic resonance technology,the purpose of sequentially locking and detecting the four formant signals on one side of the diamond NV color center(m_(s)=-1 state signal)is achieved,and the vector magnetic field information detection is accomplished by combining the triaxial magnetic information solution model.The system can obtain magnetic field detection in a range of 0 mT-0.82 mT.The system's magnetic noise sensitivity is 14.2 nT/Hz^(1/2),and the deviation angle errors of magnetic field detectionθ_(x) andθ_(y) are 1.3° and 8.2° respectively.

Scalable Quantum Information Transfer between Individual Nitrogen-Vacancy Centers by a Hybrid Quantum Interface

We develop a design of a hybrid quantum interface for quantum information transfer （QIT）, adopting a nanome- chanical resonator as the intermedium, which is magnetically coupled with individual nitrogen-vacancy centers as the solid qubits, while eapacitively coupled with a coplanar waveguide resonator as the quantum data bus. We describe the Hamiltonian of the model, and analytically demonstrate the QIT for both the resonant interaction and large detuning cases. The hybrid quantum interface allows for QIT between arbitrarily selected individual nitrogen-vacancy centers, and has advantages of the sealability and controllability. Our methods open an alter- native perspective for implementing QIT, which is important during quantum storing or processing procedures in quantum computing.

Development of Information Triangulation Method for Prediction of Earthquake Center Zone Using Distributed Measurements of Emitted Electromagnetic Radiation

The new method for prediction of earthquake center zone is suggested. The method is based on feature of amount of registered information to reach its maximum upon some condition regulating interrelation of major parameters of used distributed measuring system. The mathematical basis of suggested is based on known integrated Shannon formula of amount of information and integral limitation condition, expressing fixed position of used sensors. As a result of held researches, new method of information trangulation method for determination of earthquake center zone is suggested. The mathematical grounding and the operational algorithm of the method are given.

Self-cognition and self-education at ecomuseum：From ＂Information Center＂ to ＂Cognition Center＂

Anji Ecomuseum is the kind of ＂grown-up ecomuseum＂ which differs from the traditional eco-museum in the sense of those originating in 1970s France, and transferred to China （Via Norway） inGuizhou and later in Guangxi. Anji Ecomuseum created the ＂cognition center＂ instead of ＂informationcenter＂. Cognition center adds more values to the community, encourages the locals and audiences fromoutside to understand （not only learn from） Eco-community as a whole, emphasizing the living heritage,self-cognition and self-education. Graburn discussed this evolution was closer to the root of Eco.

China National Engineering Research Center for Information Technology in Agriculture

China National Engineering Research Center for Information Technology in Agriculture （NERCITA） was established in 2001 with the approval of the Ministry of Science and Technology of China. As a national research institution, it mainly engages in research and development of agricultural and rural informatization engineering technology. Based on the requirements of agricultural and rural development of China, the major mission of NERCITA is to make key technology innovation, establish technical platform and develop significant products for agriculture, which focus on five aspects： intelligent information processing technology, remote sensing and geographic information system, precision agriculture, biological environment control engineering and automation technology as well as fast detection techniques of agricultural product security and the monitoring technology of farmland environmental quality. The ultimate goal is to provide a powerful technological support for agricultural modernization and rural development.

Design and Key Technology of Gardening Information Management System Based on Data Center

To provide scientific management basis for the garden planning, project construction, maintenance, social service, this paper prompted that the urban gardening administration sectors need to construct gardening information management system. On the basis of fully requirements analysis of gardening sectors, this paper discussed the key technology for system construction. It also proposed to flexibly and smartly build up the system by using the secondary development design environment and running environment based on data center integration development platform. This system greatly helps the daily management and plays very important role in improving urban ecological environment and investment environment.

CAS COMPUTER NETWORK INFORMATION CENTER

The Computer Network Information Center(CNIC) is a newly-established CAS institute,which is engaged in the research and development of network and scientific databases.At present the Center is in charge of two key projects:a scientific database project and a national computing and networking facility of China (NCFC).

CHINA RARE EARTH INFORMATION CENTER

China Rare Earth——1995 In 1995 both domestic and overseas RE markets were unprecedentedly brisk. The Chinese rare earth industry seized the opportunity and its efforts on developing the both markets were rewarded by overfulfilling the set Eighth-Five Year Plan. And the new record highs were set in rare earth production,application and export. In the year, the country’s rare earth mineral products reached 48002 ton REO, up 56.6％, rare earth commercial products after metallurgical pro-

Influence of initial check, information exchange, final accuracy check, reaction information nursing on the psychology of elderly with lung cancer

BACKGROUND As one of the fatal diseases with high incidence,lung cancer has seriously endangered public health and safety.Elderly patients usually have poor self-care and are more likely to show a series of psychological problems.AIM To investigate the effectiveness of the initial check,information exchange,final accuracy check,reaction(IIFAR)information care model on the mental health status of elderly patients with lung cancer.METHODS This study is a single-centre study.We randomly recruited 60 elderly patients with lung cancer who attended our hospital from January 2021 to January 2022.These elderly patients with lung cancer were randomly divided into two groups,with the control group taking the conventional propaganda and education and the observation group taking the IIFAR information care model based on the conventional care protocol.The differences in psychological distress,anxiety and depression,life quality,fatigue,and the locus of control in psychology were compared between these two groups,and the causes of psychological distress were analyzed.RESULTS After the intervention,Distress Thermometer,Hospital Anxiety and Depression Scale(HADS)for anxiety and the HADS for depression,Revised Piper’s Fatigue Scale,and Chance Health Locus of Control scores were lower in the observation group compared to the pre-intervention period in the same group and were significantly lower in the observation group compared to those of the control group(P<0.05).After the intervention,Quality of Life Questionnaire Core 30(QLQ-C30),Internal Health Locus of Control,and Powerful Others Health Locus of Control scores were significantly higher in the observation and the control groups compared to the pre-intervention period in their same group,and QLQ-C30 scores were significantly higher in the observation group compared to those of the control group(P<0.05).CONCLUSION The IIFAR information care model can help elderly patients with lung cancer by reducing their anxiety and depression,psychological distress,and fatigue,improving their tendencies on the locus of control in psychology,and enhancing their life qualities.

Attribute Reduction of Hybrid Decision Information Systems Based on Fuzzy Conditional Information Entropy

The presence of numerous uncertainties in hybrid decision information systems(HDISs)renders attribute reduction a formidable task.Currently available attribute reduction algorithms,including those based on Pawlak attribute importance,Skowron discernibility matrix,and information entropy,struggle to effectively manages multiple uncertainties simultaneously in HDISs like the precise measurement of disparities between nominal attribute values,and attributes with fuzzy boundaries and abnormal values.In order to address the aforementioned issues,this paper delves into the study of attribute reduction withinHDISs.First of all,a novel metric based on the decision attribute is introduced to solve the problem of accurately measuring the differences between nominal attribute values.The newly introduced distance metric has been christened the supervised distance that can effectively quantify the differences between the nominal attribute values.Then,based on the newly developed metric,a novel fuzzy relationship is defined from the perspective of“feedback on parity of attribute values to attribute sets”.This new fuzzy relationship serves as a valuable tool in addressing the challenges posed by abnormal attribute values.Furthermore,leveraging the newly introduced fuzzy relationship,the fuzzy conditional information entropy is defined as a solution to the challenges posed by fuzzy attributes.It effectively quantifies the uncertainty associated with fuzzy attribute values,thereby providing a robust framework for handling fuzzy information in hybrid information systems.Finally,an algorithm for attribute reduction utilizing the fuzzy conditional information entropy is presented.The experimental results on 12 datasets show that the average reduction rate of our algorithm reaches 84.04%,and the classification accuracy is improved by 3.91%compared to the original dataset,and by an average of 11.25%compared to the other 9 state-of-the-art reduction algorithms.The comprehensive analysis of these research results clearly indicates that our algorithm is highly effective in managing the intricate uncertainties inherent in hybrid data.

Establishment of a National Biomedical Information Center Proposed

Bioinformatics research institutes or centers have made their debut in China in recent years. However, their capacity and academic build-up are not satisfactory. In order to keep abreast with the advanced international level in terms of scholarship, a well-known Chinese scientist has called on the central authorities to set up a national biomedical information center. Duplicate construction of bioinformatics institutions would be a waste of scarce resources,

Business Process Analysis and Simulation: The Contact Center of a Public Health and Social Information Office

This article proposes a framework, called BP-M* which includes: 1) a methodology to analyze, engineer, restructure and implement business processes, and 2) a process model that extends the process diagram with the specification of resources that execute the process activities, allocation policies, schedules, times of activities, management of queues in input to the activities and workloads so that the same model can be simulated by a discrete event simulator. The BP-M* framework has been applied to a real case study, a public Contact Center which provides different typologies of answers to users’ requests. The simulation allows to study different system operating scenarios (“What-If” analysis) providing useful information for analysts to evaluate restructuring actions.

Robust Information Hiding Based on Neural Style Transfer with Artificial Intelligence

This paper proposes an artificial intelligence-based robust information hiding algorithm to address the issue of confidential information being susceptible to noise attacks during transmission.The algorithm we designed aims to mitigate the impact of various noise attacks on the integrity of secret information during transmission.The method we propose involves encoding secret images into stylized encrypted images and applies adversarial transfer to both the style and content features of the original and embedded data.This process effectively enhances the concealment and imperceptibility of confidential information,thereby improving the security of such information during transmission and reducing security risks.Furthermore,we have designed a specialized attack layer to simulate real-world attacks and common noise scenarios encountered in practical environments.Through adversarial training,the algorithm is strengthened to enhance its resilience against attacks and overall robustness,ensuring better protection against potential threats.Experimental results demonstrate that our proposed algorithm successfully enhances the concealment and unknowability of secret information while maintaining embedding capacity.Additionally,it ensures the quality and fidelity of the stego image.The method we propose not only improves the security and robustness of information hiding technology but also holds practical application value in protecting sensitive data and ensuring the invisibility of confidential information.

Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis

BACKGROUND Acute liver failure(ALF)has a high mortality with widespread hepatocyte death involving ferroptosis and pyroptosis.The silent information regulator sirtuin 1(SIRT1)-mediated deacetylation affects multiple biological processes,including cellular senescence,apoptosis,sugar and lipid metabolism,oxidative stress,and inflammation.AIM To investigate the association between ferroptosis and pyroptosis and the upstream regulatory mechanisms.METHODS This study included 30 patients with ALF and 30 healthy individuals who underwent serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)testing.C57BL/6 mice were also intraperitoneally pretreated with SIRT1,p53,or glutathione peroxidase 4(GPX4)inducers and inhibitors and injected with lipopolysaccharide(LPS)/D-galactosamine(D-GalN)to induce ALF.Gasdermin D(GSDMD)^(-/-)mice were used as an experimental group.Histological changes in liver tissue were monitored by hematoxylin and eosin staining.ALT,AST,glutathione,reactive oxygen species,and iron levels were measured using commercial kits.Ferroptosis-and pyroptosis-related protein and mRNA expression was detected by western blot and quantitative real-time polymerase chain reaction.SIRT1,p53,and GSDMD were assessed by immunofluorescence analysis.RESULTS Serum AST and ALT levels were elevated in patients with ALF.SIRT1,solute carrier family 7a member 11(SLC7A11),and GPX4 protein expression was decreased and acetylated p5,p53,GSDMD,and acyl-CoA synthetase long-chain family member 4(ACSL4)protein levels were elevated in human ALF liver tissue.In the p53 and ferroptosis inhibitor-treated and GSDMD^(-/-)groups,serum interleukin(IL)-1β,tumour necrosis factor alpha,IL-6,IL-2 and C-C motif ligand 2 levels were decreased and hepatic impairment was mitigated.In mice with GSDMD knockout,p53 was reduced,GPX4 was increased,and ferroptotic events(depletion of SLC7A11,elevation of ACSL4,and iron accumulation)were detected.In vitro,knockdown of p53 and overexpression of GPX4 reduced AST and ALT levels,the cytostatic rate,and GSDMD expression,restoring SLC7A11 depletion.Moreover,SIRT1 agonist and overexpression of SIRT1 alleviated acute liver injury and decreased iron deposition compared with results in the model group,accompanied by reduced p53,GSDMD,and ACSL4,and increased SLC7A11 and GPX4.Inactivation of SIRT1 exacerbated ferroptotic and pyroptotic cell death and aggravated liver injury in LPS/D-GalNinduced in vitro and in vivo models.CONCLUSION SIRT1 activation attenuates LPS/D-GalN-induced ferroptosis and pyroptosis by inhibiting the p53/GPX4/GSDMD signaling pathway in ALF.

Distribution area demarcation for logistic centers under geographical information system decision support system

Demarcating distribution area of goods is often guided by the rule of thumb by business proprietors. However, this method seems to be unsuitable when the demand points increase to a certain large extent. The present work attempted to convert the problem of distribution area demarcation into a localized problem of warehouseing and networking, and tried to establish district-based planning mode based on location based heuristic (LBH). Two methods were used in this study: 1) the manual method to construct the mathematical model and conduct simulation; 2) the automatic method using TransCAD software of geographical information system (GIS) for simulation. By comparing the effects of the two methods, the research provides theoretical support for business proprietors to demarcate the distribution area rationally with the application of GIS system. The results show that GIS has very good graphics construction function to replace complex text, and the automatic demarcating mode with human-machine interaction provides a good business decision-making support.

Groundbreaking Ceremony for the Building of Informationε-Commercial Center of Textileε-Clothing China

A new textile commercial center is being built in Hangzhou, capital city of Zhejiang province. The groundbreaking on April 20th was more ceremonious for this event than it was many a time before, as the project marks the shift for an innovation-led direction in this world’s largest textile province.