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Breast Thermography: A 20-Year Retrospective Review of Infra-Red Breast Thermal Imaging in New Zealand and Its Potential Role in Breast Health Management
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作者 Michael Godfrey Patricia Godfrey 《Advances in Breast Cancer Research》 2023年第4期129-141,共13页
Cases are presented to reveal how modern computerised infra-red thermal imaging has the potential to assist in early breast cancer detection. The history of thermography and some recent controversies surrounding mammo... Cases are presented to reveal how modern computerised infra-red thermal imaging has the potential to assist in early breast cancer detection. The history of thermography and some recent controversies surrounding mammography are discussed. Examples of thermal imaging combined with naturopathic interventions are described. Since 2002, more than 8000 women in New Zealand have chosen to include thermal imaging as a part of their breast health management. Breast thermal imaging combined with relevant health advice, resulted in a perceived worthwhile benefit to patients in managing overall health. 展开更多
关键词 Breast Screening MAMMOGRAPHY infra-red Thermography
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Analysis Algerian's Gallstones with Infrared Spectrum and Methods of Prevention and Treatment for Cholelithiasis in Algeria
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作者 Li Zong shan 1, Dang Zi qin 1, Li Xang qun 1, Zeng Fan qing 2, Gu Ying hong 2, Niu Fei 2, Zhang Hu sheng 3, Hung Xiao Ling 4 1. School of Medicine, Wuhan University, Wuhan 430071, Hubei, China 2. College of Chemistry and Molecular Sciences, Wuha University, Wuhan 430072, Hubei, China +1 位作者 3. School of Physics and Technology, Wuhan University, Wuhan 430072, Hubei, China 4. Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei, China 《Wuhan University Journal of Natural Sciences》 CAS 2002年第4期499-501,共3页
To analyze the type of Algerian’s gallstones and put forward relative measures of prevention and treatment, The NICOLET 170SX FT-IR spectrometer was used to measure the infra-red spectrum and analyze the feature of s... To analyze the type of Algerian’s gallstones and put forward relative measures of prevention and treatment, The NICOLET 170SX FT-IR spectrometer was used to measure the infra-red spectrum and analyze the feature of spectrum of Algerian’s gallstones. The results shown that Algerian have cholesterol gallstones. Reasons to form Algerian’s multiple cholesterol gallstones were investigated. We have put forward five suggestions to prevent and treat cholelithiasis. 展开更多
关键词 Key words Algerian GALLSTONE infra red spectrum PREVENTION TREATMENT
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Electrical Conductivity and Infra Red of CaTiO_3 Doped with CuO
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作者 F.F.Hammad and M.Sh.Khalil Department of Inorganic Chemistry, National Research Centre, Dokki, Cairo, Egypt A. H. Salama Department of Physical Chemistry, National Research Centre, Dokki, Cairo, Egypt 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2001年第6期667-669,共3页
The electrical conductivity of pure CaTiO3 and that containing 0.5~5.0 mole fraction CuO as dopant were measured in the temperature range 291~773 K. The conductivity values varied as a ... The electrical conductivity of pure CaTiO3 and that containing 0.5~5.0 mole fraction CuO as dopant were measured in the temperature range 291~773 K. The conductivity values varied as a function of temperature and dopant concentration. The activation energy in the lower temper- ature range depended on the impurity content while in the high temperature range it indicated a value of energy gap width. The infrared absorption spectra in the range of 100~4000 cm-1 revealed the presence of two main bands at 340 and 570 cm-1 which were assigned to Ti06 oc- tahedral normal mode. Bands in the range of 106~270 cm-1 were due to the vibration of anion TiO3-2. Some bands were observed at higher values due to the presence of lattice imperfections. There was a slight shift in band position with increasing dopant concentration which favors the formation of orthorhombic modification. 展开更多
关键词 Electrical Conductivity and infra red of CaTiO3 Doped with CuO TIO In
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The First Light of Beijing Infra -Red Array Camera
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《天文研究与技术》 CSCD 1999年第S1期158-158,共1页
关键词 red Array Camera The First Light of Beijing infra
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Evaluation of the Performance of Infrared Thermography for On-Line Condition Monitoring of Rotating Machines
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作者 Vincent Leemans Marie-France Destain +1 位作者 Bovic Kilundu Pierre Dehombreux 《Engineering(科研)》 2011年第10期1030-1039,共10页
This study evaluated the possibility of infrared thermography to measure accurately the temperature of elements of a rotating device, within the scope of condition monitoring. The tested machine was a blower coupled t... This study evaluated the possibility of infrared thermography to measure accurately the temperature of elements of a rotating device, within the scope of condition monitoring. The tested machine was a blower coupled to a 500 kW electric motor, that operated in multiples regimes. The thermograms were acquired by a fixed thermographic camera and were processed and recorded every 15 minutes. Because the normal temperature variations could easily mask a drift caused by a failure, a corrected temperature was computed using autorecursive models. It was shown that an efficient temperature correction should compensate for the variations of the process, and for the ambient temperatures variations, either daily or seasonal. The standard deviation of the corrected temperature was of a few tenth of degree, making possible the detection of a drift of less than one degree and the prediction of potential failure. 展开更多
关键词 infra-red THERMOGRAPHY CONDITIONAL MONITORING ARX
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Comparative Thermometery in Paediatric Age Group: Is the Non-Touch Infrared Thermometer (NTIT) Reading Comparable to Regular Mercury-in-Glass Thermometer (MIGT) Reading?
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作者 Yetunde Olasinde Moninuola Ernest +1 位作者 Gbenga Popoola Kolade Ernest 《Open Journal of Pediatrics》 2018年第4期303-310,共8页
Background: Accurate temperature measurement is a critical step in evaluating health or disease especially in children and immmunocompromised subjects;inaccurate measurement may lead to improper diagnosis, wrong treat... Background: Accurate temperature measurement is a critical step in evaluating health or disease especially in children and immmunocompromised subjects;inaccurate measurement may lead to improper diagnosis, wrong treatment or inappropriate intervention. Several methods of temperature measurements exist and comparing these gives room for choosing a near ideal method in terms of speed, safety and accuracy. The study aimed to compare the forehead non touch infra-red thermometer with the axilllary mercury-in-glass method of temperature measurement in the Paediatric age-group. Methods: Study was given ethical approval as part of a larger study. Four hundred and thirty seven children aged 1 to 24 months were studied at the well-baby/immunizationclinic of the University of Ilorin Teaching Hospital over a 6-months period. Both non-touch infrared and theregular mercury-in-glass thermometers were used to take the body temperatures. Data were analysed with SPSS version 21. Pearson correlation was used to determine the relationship between the two methods of temperature measurements, while Bland-Altman method was used to test for level of agreement between them. Results: The mean age and SD was 5.81 ± 4.04 months. Pearson correlation showed a positive correlation between the axillary mercury-in-glass and forehead non-touch infra-red thermometry readings (r = 0.281, p < 0.001). Also, Bland-Altman method revealed a good agreement between both methods of thermometry as 96% of the readings were within the limits of agreement. Mean difference was 0.09°C (95% confidence interval 0.05 - 0.13). Conclusion: Axillary mercury-in-glass thermometer and forehead non touch infra-red thermometers have a good agreement and can be used interchangeably. 展开更多
关键词 Axillary Mercury-in-Glass THERMOMETER Forehead Non-Touch infra-red THERMOMETER Bland-Altman
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Infra-red Thermal Imaging of the Inner Canthus: Correlates with the Temperature of the Injured Human Brain
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作者 Charmaine Childs Mya Myint Zu +3 位作者 Aung Phyo Wai Yeo Tseng Tsai Shiqian Wu Wang Li 《Engineering(科研)》 2012年第10期53-56,共4页
Introduction: Infra-red (IR) thermometry is a safe and valid method to determine internal and surface temperature in human subjects. Under conditions of brain damage (head injury or stroke) knowledge of changes in the... Introduction: Infra-red (IR) thermometry is a safe and valid method to determine internal and surface temperature in human subjects. Under conditions of brain damage (head injury or stroke) knowledge of changes in the temperature of intracranial tissue is justified because of the vulnerability of neurons to accelerated damage at temperatures at the upper end of the febrile range. Aim: To determine the temperature at the inner canthus (IC) of the eye as a potential surrogate for brain temperature. Methods: Invasive monitoring of deep brain structures, lateral ventricle and deep white matter. IR temperature readings obtained at right and left IC. Results: ?Strong correlations were evident between R and L IC and brain. Close, as well as poor, agreement between?? sites was shown in some patients and at some times. For right hemispheric lesions four had a better correlation between TbrV and TRIC when compared to TLIC.? When the correlation between TbrV and TLIC was better compared to TbrV and TRIC, four had a predominant right hemispheric lesion. Conclusions: Improved techniques for IR thermal imaging accuracy at the bedside has the potential to improve temperature measurement agreement. The predominant lesion side may have a bearing on maximum ipsilateral IC temperature Further studies are ongoing in this pilot study population. 展开更多
关键词 BRAIN TEMPERATURE infra-red Thermometry INNER Canthus Thermal Imaging Eye
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农作物病虫害预警蛇形机器人避障控制研究--基于超声波及红外感器 被引量:2
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作者 黄亚萍 杨冬 《农机化研究》 北大核心 2024年第5期197-200,205,共5页
首先,搭建了农作物病虫害预警蛇形机器人运动学模型,对其被动蜿蜒转弯模式进行详细分析;然后,基于超声波和红外传感器设计了蛇形机器人控制系统,采用Serpenoid曲线策略对蛇形机器人运动姿态进行了研究,并模拟蛇的蜿蜒避障运动。模拟仿... 首先,搭建了农作物病虫害预警蛇形机器人运动学模型,对其被动蜿蜒转弯模式进行详细分析;然后,基于超声波和红外传感器设计了蛇形机器人控制系统,采用Serpenoid曲线策略对蛇形机器人运动姿态进行了研究,并模拟蛇的蜿蜒避障运动。模拟仿真结果表明:蛇形机器人可以自主检测障碍物,通过对移动速度和方向进行控制,能够实现避障处理。 展开更多
关键词 蛇形机器人 病虫害预警 超声波 红外 Serpenoid 避障
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超纤革水性含浸工艺的改进 被引量:1
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作者 李琛 王冬 +2 位作者 仲鸿天 董朋 付少海 《印染》 北大核心 2024年第1期36-39,43,共5页
针对现有水性聚氨酯含浸超纤革工艺的缺点,从基布改性和传统工艺优化二方面改进了超纤革的水性含浸工艺,研究了水性聚氨酯固含量、浆料黏度、整理及烘干方式对含浸超纤革性能的影响。结果表明:当水性聚氨酯固含量为25%、浆料黏度为2000~... 针对现有水性聚氨酯含浸超纤革工艺的缺点,从基布改性和传统工艺优化二方面改进了超纤革的水性含浸工艺,研究了水性聚氨酯固含量、浆料黏度、整理及烘干方式对含浸超纤革性能的影响。结果表明:当水性聚氨酯固含量为25%、浆料黏度为2000~3000 mPa·s时,采用等离子体改性基布,含浸后盐溶液破乳,红外照射预烘后再高温热风烘干,制备的含浸超纤革符合QB/T 2888—2007中B类绒面合成革的产品标准。 展开更多
关键词 水性聚氨酯 超纤革 固含量 黏度 等离子体 破乳 红外加热
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九蒸九制对鸡头黄精理化性质及抗氧化性的影响 被引量:1
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作者 王俊楠 卢琪 +3 位作者 薛淑静 陈晓春 张春兰 杨德 《现代食品科技》 CAS 北大核心 2024年第2期231-245,共15页
为了探究蒸制处理对鸡头黄精有效成分及代谢物种类和含量影响,采用低场核磁、苯酚-浓硫酸法、高效液相色谱-蒸发光散射检测法(HPLC-ELSD)和液相色谱-质谱技术(LC-MS)等对其中的水分分布、多糖含量、单糖组成和代谢产物等进行分析。结果... 为了探究蒸制处理对鸡头黄精有效成分及代谢物种类和含量影响,采用低场核磁、苯酚-浓硫酸法、高效液相色谱-蒸发光散射检测法(HPLC-ELSD)和液相色谱-质谱技术(LC-MS)等对其中的水分分布、多糖含量、单糖组成和代谢产物等进行分析。结果表明,多次蒸制后,鸡头黄精结合水的含量、多糖含量逐渐降低,水提液pH值逐渐降低呈弱酸性达到4.07,还原糖、总酚、黄酮含量逐渐升高分别达到28.69%、10.02 mg/g和0.69%,抗氧化性逐渐增强,ABTS抗氧化能力在7制达到最高为0.73 mmol/L,较1制增加0.35 mmol/L,DPPH自由基清除率和FRAP值在8制达到最高分别为81.95%,1.97 mmol/L,较1制分别增加50.92%,1.72 mmol/L;同时蔗糖逐渐水解从18.53mg/g到7.62mg/g,葡萄糖和果糖含量提高,分别由1制0.00和11.30mg/g,达到9制17.25和230.89 mg/g。选取一制与九制黄精进行代谢物差异分析,在正离子模式下共检测到1310种代谢物,差异代谢物有176种(按其特性分为38类),在负离子模式下共检测到1841种代谢物,差异代谢物有148种(按其特性分为26类)。黄精经蒸制后有效成分差异性显著,对鸡头黄精炮制加工提供科学依据。 展开更多
关键词 鸡头黄精 九蒸九制 HPLC-ELSD LC-MS 代谢组学分析
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基于UPLC-QqQ-MS/MS测定人参属中药对甲亢大鼠类固醇激素含量的影响 被引量:1
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作者 金墨竹 刘琳琳 窦德强 《质谱学报》 EI CAS CSCD 北大核心 2024年第4期540-551,I0004,共13页
本研究利用超高效液相色谱-三重四极杆串联质谱(UPLC-QqQ-MS/MS)联用技术定量测定甲亢大鼠血清中肾上腺素和多种类固醇激素,探讨血清中类固醇激素含量与甲状腺功能亢进的相关性,以及不同药性人参属中药红参和人参叶对甲亢高代谢的改善... 本研究利用超高效液相色谱-三重四极杆串联质谱(UPLC-QqQ-MS/MS)联用技术定量测定甲亢大鼠血清中肾上腺素和多种类固醇激素,探讨血清中类固醇激素含量与甲状腺功能亢进的相关性,以及不同药性人参属中药红参和人参叶对甲亢高代谢的改善作用。采用主成分分析(PCA)、Spearman检验进行肾上腺素和类固醇激素与甲状腺功能的相关性分析。结果表明,UPLC-QqQ-MS/MS能够快速检测待测物的含量和变化,灵敏度高、重现性好、准确率高且分析速度快。与空白组相比,甲亢大鼠血清中类固醇激素含量均有不同程度的降低,给予不同药性人参属中药后均出现升高。类固醇激素水平异常在一定程度上与甲状腺激素有关,皮质酮和肾上腺素可作为中药调节类固醇激素代谢的关键指标;睾酮可作为寒性中药调节类固醇激素的生物标志物;肾上腺素和雄烯二酮可作为温性中药调节类固醇激素的生物标志物。该方法能够系统、快速、准确、高效地完成大鼠血清中类固醇激素含量的测定,为类固醇激素的分析测定提供方法参考。 展开更多
关键词 甲亢 肾上腺素 类固醇激素 超高效液相色谱-三重四极杆串联质谱(UPLC-QqQ-MS/MS) 红参 人参叶 定量测定
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花生红衣中反式白藜芦醇对HEK293T细胞抗氧化的影响
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作者 孙畅 周春田 +5 位作者 岳玉兰 吕呈蔚 李云飞 黄威 李铁柱 胡济美 《中国食品学报》 EI CAS CSCD 北大核心 2024年第5期150-160,共11页
目的:分析花生红衣中的白藜芦醇成分,探究其主要成分反式白藜芦醇(RES)对人胚胎肾细胞293(HEK293T)抗氧化的影响及其潜在的分子机制。方法:采用超声波辅助酶法提取花生红衣中的白藜芦醇,采用高效液相色谱-质谱联用(HPLC-MS)技术分析花... 目的:分析花生红衣中的白藜芦醇成分,探究其主要成分反式白藜芦醇(RES)对人胚胎肾细胞293(HEK293T)抗氧化的影响及其潜在的分子机制。方法:采用超声波辅助酶法提取花生红衣中的白藜芦醇,采用高效液相色谱-质谱联用(HPLC-MS)技术分析花生红衣中白藜芦醇粗提液的组成成分。通过测定细胞活力,检测RES对HEK293T细胞的最高毒性。通过荧光素酶报告基因试验及免疫印迹试验检测其对Keap1-Nrf2-ARE抗氧化信号通路的影响,以DPPH自由基清除率评价其体外抗氧化能力。结果:HPLC-MS结果表明,花生红衣中含有白藜芦醇苷、白皮杉醇和RES。由于白藜芦醇在自然界中主要以反式白藜芦醇形式存在,因此选择RES进行后续试验。细胞存活力检测结果表明,RES对HEK293T细胞的最高无毒浓度为50μmol/L,体外抗氧化作用呈浓度依赖性。荧光素酶报告基因分析表明,RES显著诱导了ARE介导的转录激活。免疫印迹结果显示,RES能诱导Nrf2介导的3个抗氧化蛋白表达【血红素氧合酶1(HO-1)、醌氧化还原酶1(NQO1)和谷氨酸半胱氨酸连接酶(GCLM)】表达。此外,DPPH自由基清除率测定结果表明,RES能有效清除DPPH自由基,具有体外抗氧化能力。结论:花生红衣中白藜芦醇的主要成分RES对HEK293T细胞有抗氧化作用,可通过Keap1-Nrf2-ARE信号通路激活潜在的抗氧化活性。 展开更多
关键词 花生红衣 白藜芦醇 HEK293T 高效液相色谱-质谱联用 Keap1-Nrf2-ARE信号通路 抗氧化
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飞行时间-高分辨质谱法分析红曲类食品中他汀类物质 被引量:1
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作者 段琼 马春艳 +4 位作者 赵振霞 苏建 孟珊 封淑华 刘雪莉 《河北师范大学学报(自然科学版)》 CAS 2024年第2期158-166,共9页
采用飞行时间-高分辨质谱法对22批次保健食品和普通食品中他汀类物质进行了分析,并总结了其裂解规律.利用高效液相色谱法测定了保健食品和普通食品中洛伐他汀总含量,内酯型与酸型洛伐他汀的比例.结果表明,保健食品及普通食品D1,D2中他... 采用飞行时间-高分辨质谱法对22批次保健食品和普通食品中他汀类物质进行了分析,并总结了其裂解规律.利用高效液相色谱法测定了保健食品和普通食品中洛伐他汀总含量,内酯型与酸型洛伐他汀的比例.结果表明,保健食品及普通食品D1,D2中他汀类物质含量较高,不同样品中内酯型与酸型洛伐他汀的总含量及比例不同;保健食品中洛伐他汀日服用量在国家规定的安全范围内;大部分普通食品中未检出他汀类物质. 展开更多
关键词 红曲食品 飞行时间-高分辨质谱 质谱解析 美伐他汀类似物 洛伐他汀总含量
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电子鼻结合HS-SPME-GC-MS技术解析贵州主产区红酸汤香气成分
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作者 陆敏 陈菊 +4 位作者 王雪雅 殷勇 孙小静 李文馨 何建文 《中国酿造》 CAS 北大核心 2024年第11期231-236,共6页
利用电子鼻结合顶空固相微萃取-气质联用(HS-SPME-GC-MS)技术检测红酸汤样品的挥发性风味成分,通过测色仪测定红酸汤的颜色参数,采用正交偏最小二乘法判别分析(OPLS-DA)构建模型,研究贵州主产区红酸汤的香气成分构成及差异。基于气味活... 利用电子鼻结合顶空固相微萃取-气质联用(HS-SPME-GC-MS)技术检测红酸汤样品的挥发性风味成分,通过测色仪测定红酸汤的颜色参数,采用正交偏最小二乘法判别分析(OPLS-DA)构建模型,研究贵州主产区红酸汤的香气成分构成及差异。基于气味活度值(OAV)和变量投影重要性(VIP)值筛选关键风味物质(OAV>1)和关键差异风味物质(OAV>1且VIP>1)。结果表明,4种红酸汤样品的L^(*)值、a^(*)值、b^(*)值存在显著差异(P<0.05)。电子鼻分析结果表明,4种红酸汤样品具有相似的风味轮廓,但其挥发性风味物质有所差异,对硫化物、芳香类化合物电子鼻响应值最高,基于电子鼻响应值的主成分分析(PCA)及线性判别分析(LDA)能够有效区分不同产区红酸汤样品。通过HS-SPME-GC-MS从4种红酸汤样品中共检测出132种挥发性风味物质,其中3个及以上红酸汤样品共有的香气物质26种。红酸汤样品中筛选出9种关键风味物质和2种关键差异风味物质。 展开更多
关键词 红酸汤 贵州主产区 电子鼻 顶空固相微萃取-气质联用 香气成分
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Congophilic fibrils in the glomeruli with polyclonal immunoglobulin gamma staining-another cause for diagnostic overlap:A case report
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作者 Maria Bernadette Che-Ying Chow Lucas Bushrow +3 位作者 Irmeen Siddiqui April Chiu Mirza Hamirani Anjali A Satoskar 《World Journal of Clinical Cases》 SCIE 2024年第17期3200-3205,共6页
BACKGROUND Glomerulopathy with fibrillary deposits is not uncommon in routine nephropathology practice,with amyloidosis and fibrillary glomerulonephritis being the two most frequently encountered entities.Renal amyloi... BACKGROUND Glomerulopathy with fibrillary deposits is not uncommon in routine nephropathology practice,with amyloidosis and fibrillary glomerulonephritis being the two most frequently encountered entities.Renal amyloid heavy and light chain(AHL)is relatively uncommon and its biopsy diagnosis is usually limited to cases that show strong equivalent staining for a single immunoglobulin(Ig)heavy chain and a single light chain,further supported by mass spectrometry(MS)and serum studies for monoclonal protein.But polyclonal light chain staining can pose a challenge.CASE SUMMARY Herein we present a challenging case of renal AHL with polyclonal and polytypic Ig gamma(IgG)staining pattern by immunofluorescence.The patient is a 62-yearold Caucasian male who presented to an outside institution with a serum creatinine of up to 8.1 mg/dL and nephrotic range proteinuria.Despite the finding of a polyclonal and polytypic staining pattern on immunofluorescence,ultrastructural study of the renal biopsy demonstrated the presence of fibrils with a mean diameter of 10 nm.Congo red was positive while DNAJB9 was negative.MS suggested a diagnosis of amyloid AHL type with IgG and lambda,but kappa light chains were also present supporting the immunofluorescence staining results.Serum immunofixation studies demonstrated IgG lambda monoclonal spike.The patient was started on chemotherapy.The chronic renal injury however was quite advanced and he ended up needing dialysis shortly after.CONCLUSION Tissue diagnosis of AHL amyloid can be tricky.Thorough confirmation using other available diagnostic techniques is recommended in such cases. 展开更多
关键词 Heavy and light chain amyloid Fibrillary glomerulonephritis DNAJB9 Serum immunofixation Protein electrophoresis Mass spectrometry Congo red Case report
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锆基金属有机骨架复合材料用于海水中短裸甲藻毒素的固相萃取
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作者 陈宗保 谢诗烨 +3 位作者 刘泳君 张文敏 方敏 张兰 《色谱》 CAS CSCD 北大核心 2024年第9期819-826,共8页
短裸甲藻毒素(BTX-A)是由有害藻类短裸甲藻产生的次生代谢物,检测海水中的藻毒素可以预测赤潮的发生和增长。将BTX-A含量监测作为赤潮预警的因子之一可以有效提高赤潮预警的准确性,开发一种高效富集海水中BTX-A的样品前处理方法迫在眉... 短裸甲藻毒素(BTX-A)是由有害藻类短裸甲藻产生的次生代谢物,检测海水中的藻毒素可以预测赤潮的发生和增长。将BTX-A含量监测作为赤潮预警的因子之一可以有效提高赤潮预警的准确性,开发一种高效富集海水中BTX-A的样品前处理方法迫在眉睫。研究通过溶剂热法制备了具有较大比表面积(3109 m2/g)、对BTX-A有较强吸附作用的微米级Zr-MOFs复合材料(SiO_(2)@UiO-66),并将其作为固相萃取(SPE)填料,结合高效液相色谱-串联质谱(HPLC-MS/MS)技术,建立了一种检出限低(30 pg/mL)、线性范围宽(100~2000 pg/mL)、重复性良好(RSD≤85%,n=6)的海水中BTX-A的高灵敏检测方法。所建立的分析方法成功用于实际海水样品中BTX-A含量的分析和监测,结合福建省海洋与渔业局所发布的赤潮监测预警信息,可作为赤潮预警因子有效提高赤潮的监测和预警。 展开更多
关键词 金属有机骨架 短裸甲藻毒素 固相萃取 高效液相色谱-串联质谱 赤潮
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液相色谱-串联质谱法测定禽蛋及蛋制品中的苏丹红
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作者 罗峰 余健 +2 位作者 黄亚梅 杨阳 黄立 《食品安全导刊》 2024年第5期98-104,共7页
目的:建立液相色谱-串联质谱法测定禽蛋及蛋制品中的苏丹红残留量的分析方法。方法:乙腈提取,Captiva EMR-Lipid萃取柱净化;采用Waters ACQUITYUPLCBEHC_(18)(100 mm×2.1 mm,1.7μm)色谱柱,0.2%的甲酸水+乙腈为流动相梯度洗脱,流速... 目的:建立液相色谱-串联质谱法测定禽蛋及蛋制品中的苏丹红残留量的分析方法。方法:乙腈提取,Captiva EMR-Lipid萃取柱净化;采用Waters ACQUITYUPLCBEHC_(18)(100 mm×2.1 mm,1.7μm)色谱柱,0.2%的甲酸水+乙腈为流动相梯度洗脱,流速为0.30 mL·min^(-1);电喷雾离子源,正离子扫描,多反应监测;开展方法学验证,评估了方法的线性范围、检出限、定量限、准确性、精密度和稳定性。结果:4种苏丹红残留液相色谱串联质谱法加标回收率在62.6%~110.0%,精密度相对标准偏差在1.20%~6.41%,检出限为5μg·kg^(-1),相关线性系数在0.997以上。结论:本方法通过乙腈提取萃取和Captiva EMR-Lipid萃取柱净化,有效去除干扰物质,并保证苏丹红的定量准确性,然后利用液相色谱-串联质谱仪进行分析,提高了检测灵敏度,该方法能够准确、可靠地测定禽蛋及蛋制品中苏丹红的残留量。该方法的建立为监督和控制禽蛋质量安全提供了一个重要的分析手段。 展开更多
关键词 鸡蛋 鸭蛋 咸鸭蛋 苏丹红 液相色谱-串联质谱法
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液相色谱串联质谱法测定化妆品中酸性红73和溶剂红1的含量
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作者 杨斌 《香料香精化妆品》 CAS 2024年第1期119-125,共7页
建立同时测定化妆品中酸性红73和溶剂红1含量的液相色谱串联质谱(LC-MS)检测方法。试样经四氢呋喃、氨水溶液或水、氯化钠超声分散提取后加入甲醇,再超声离心,经0.22μm的滤膜过滤,然后进行检测,采用电喷雾离子源正离子(ESI~+)多反应监... 建立同时测定化妆品中酸性红73和溶剂红1含量的液相色谱串联质谱(LC-MS)检测方法。试样经四氢呋喃、氨水溶液或水、氯化钠超声分散提取后加入甲醇,再超声离心,经0.22μm的滤膜过滤,然后进行检测,采用电喷雾离子源正离子(ESI~+)多反应监测(MRM)模式测定,保留时间和相对离子对丰度定性,外标法定量。结果表明,样品中酸性红73和溶剂红1在2.0~1 000.0μg/L呈线性关系,线性相关系数大于0.999;检出限为0.034 mg/kg,定量限为0.100 mg/kg;平均回收率为73.1%~112.8%,相对标准偏差(RSD)为1.23%~6.09%(n=6)。该方法操作简便、准确、灵敏度高、回收率和重复性好,适合于化妆品中酸性红73和溶剂红1的测定。 展开更多
关键词 化妆品 酸性红73 溶剂红1 液相色谱串联质谱法 外标法
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共振光散射光谱法和可见分光光度法测定酒石酸泰乐菌素的含量
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作者 袁莉 刘毅 +2 位作者 储文 袁嘉怡 马卫兴 《理化检验(化学分册)》 CAS CSCD 北大核心 2024年第4期358-364,共7页
将注射用酒石酸泰乐菌素样品稀释一定倍数后,分取1.20 mL样品稀释液、1.25 mL pH 3.0 Clark-Lubs(克拉克-鲁布斯)缓冲溶液和1.25 mL 1×10^(-4)mol·L^(-1)虎红溶液,室温反应20 min,用水稀释至10 mL。在315 nm处分别测量空白溶... 将注射用酒石酸泰乐菌素样品稀释一定倍数后,分取1.20 mL样品稀释液、1.25 mL pH 3.0 Clark-Lubs(克拉克-鲁布斯)缓冲溶液和1.25 mL 1×10^(-4)mol·L^(-1)虎红溶液,室温反应20 min,用水稀释至10 mL。在315 nm处分别测量空白溶液(I_(0))及样品溶液(I)的共振光散射强度,计算共振光散射强度差值ΔI=I-I_(0)。分取1.00 mL样品稀释液、0.75 mL pH 3.4 Clark-Lubs缓冲溶液和2.50 mL 5×10^(-4)mol·L^(-1)虎红溶液,室温反应30 min,用水稀释至10 mL。以水为参比,在564 nm处测量空白溶液(A_(0))和样品溶液(A)的吸光度,计算吸光度差值ΔA=A-A_(0)。结果显示:酒石酸泰乐菌素的质量浓度分别在0.3~1.2 mg·L^(-1)内和ΔI呈线性关系,在4.0~48.0 mg·L^(-1)内和ΔA呈线性关系。2种方法的检出限分别为0.022 mg·L^(-1)和0.107 mg·L^(-1),回收率分别为99.0%~101%和98.2%~101%,测定值的RSD均小于1.0%。推断了2种方法的反应机理,ΔI和ΔA随酒石酸泰乐菌素质量浓度增加而增大的现象均和形成了离子缔合型超分子聚集体有关,形成的离子缔合型超分子聚集体中酒石酸泰乐菌素和虎红的物质的量比分别为1:6和1:24。 展开更多
关键词 酒石酸泰乐菌素 虎红 离子缔合型超分子聚集体 共振光散射光谱法 可见分光光度法
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眼部彩妆类化妆品中13种禁用着色剂的使用情况
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作者 张高飞 汪晨霞 +3 位作者 丁雯倩 于玥 邱颖姮 王晓炜 《香料香精化妆品》 CAS 2024年第5期105-109,共5页
为了调查国产眼部彩妆类化妆品中禁用着色剂的使用现状,采用GB/T 34806—2017《化妆品中13种禁用着色剂的测定高效液相色谱法》对100批眼部彩妆类化妆品进行监测分析。结果共有19批样品检出禁用着色剂颜料红53,其余12种禁用着色剂均未检... 为了调查国产眼部彩妆类化妆品中禁用着色剂的使用现状,采用GB/T 34806—2017《化妆品中13种禁用着色剂的测定高效液相色谱法》对100批眼部彩妆类化妆品进行监测分析。结果共有19批样品检出禁用着色剂颜料红53,其余12种禁用着色剂均未检出,样品不合格率为19.0%。通过配方成分比对与结果分析,推测颜料红53可能作为原料颜料红57的杂质被引入到产品中,建议加强对眼部彩妆类化妆品中禁用着色剂的质量安全监管和原料质量控制研究。 展开更多
关键词 眼部彩妆 禁用着色剂 高效液相色谱-串联质谱 颜料红53 颜料红57
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