期刊文献+
共找到15,995篇文章
< 1 2 250 >
每页显示 20 50 100
Advances in clinical applications of bioceramics in the new regenerative medicine era
1
作者 Noha Elshazly Fayza Eid Nasr +2 位作者 Ayat Hamdy Safa Saied Mohamed Elshazly 《World Journal of Clinical Cases》 SCIE 2024年第11期1863-1869,共7页
In this editorial,we comment on the hard and soft tissue applications of different ceramic-based scaffolds prepared by different mechanisms such as 3D printing,sol-gel,and electrospinning.The new concept of regenerati... In this editorial,we comment on the hard and soft tissue applications of different ceramic-based scaffolds prepared by different mechanisms such as 3D printing,sol-gel,and electrospinning.The new concept of regenerative medicine relies on biomaterials that can trigger in situ tissue regeneration and stem cell recruitment at the defect site.A large percentage of these biomaterials is ceramic-based as they provide the essential requirements of biomaterial principles such as tailored multisize porosity,antibacterial properties,and angiogenic properties.All these previously mentioned properties put bioceramics on top of the hierarchy of biomaterials utilized to stimulate tissue regeneration in soft and hard tissue wounds.Multiple clinical applications registered the use of these materials in triggering soft tissue regeneration in healthy and diabetic patients such as bioactive glass nanofibers.The results were promising and opened new frontiers for utilizing these materials on a larger scale.The same results were mentioned when using different forms and formulas of bioceramics in hard defect regeneration.Some bioceramics were used in combination with other polymers and biological scaffolds to improve their regenerative and mechanical properties.All this progress will enable a larger scale of patients to receive such services with ease and decrease the financial burden on the government. 展开更多
关键词 Regenerative medicine BIOCERAMICS Chronic wounds Bone defects clinical applications
下载PDF
Current Status of Clinical Application and Basic Research on Draba nemerosa Hebecarpa Jujube Lung-Diarrhoea Soup
2
作者 Yong Fan 《Journal of Biosciences and Medicines》 2024年第5期144-153,共10页
The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic r... The clinical application and basic research of Draba nemerosa Hebecarpa jujube diarrhoea lung soup focus on respiratory diseases and circulatory diseases, and its clinical application is more compared with the basic research, and Draba nemerosa Hebecarpa jujube diarrhoea lung soup is mostly used in the form of “Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup with additional subtractions or other formulas combining Draba nemerosa Hebecarpa Hebecarpa Hebecarpa jujube diarrhoea lung soup” in the clinical application. This article will focus on the main mechanisms of Draba nemerosa Hebecarpa jujube diarrhoea lung soup and its main components in the treatment of respiratory and circulatory diseases, and will give a review of the basic research on Draba nemerosa Hebecarpa Hebecarpa jujube diarrhoea lung soup as follows. 展开更多
关键词 Draba nemerosa Hebecarpa Jujube Laxative Lung Soup clinical application Basic Research
下载PDF
Study on The Current Status and Progress of Clinical Application of Ciprofol
3
作者 Lihua Liu Xiaokun Shen 《Journal of Clinical and Nursing Research》 2024年第6期166-170,共5页
Ciprofol,as a new type of short-acting intravenous anesthetic drug,belongs to the category of gamma-aminobutyric acid(GABA)receptor agonists.Its unique chemical structure,through the introduction of the cyclopropyl gr... Ciprofol,as a new type of short-acting intravenous anesthetic drug,belongs to the category of gamma-aminobutyric acid(GABA)receptor agonists.Its unique chemical structure,through the introduction of the cyclopropyl group in the isopropyl side chain of propofol,constructs a new type of chiral molecule,which significantly enhances the spatial effect,and improves the affinity for GABA receptors.Its pharmacological properties are characterized by high potency,rapid onset of action,rapid recovery,low accumulation,and minimal adverse reactions.Therefore,it has a wide range of applications in various endoscopic diagnostic and therapeutic operations,ICU sedation,and general anesthesia.In this paper,the related knowledge of ciprofol and the development of clinical application research are comprehensively sorted out and synthesized,to provide a solid theoretical basis for the rational application of ciprofol in clinical practice.At the same time,the future research direction of ciprofol will also be prospected to provide valuable references for research in related fields. 展开更多
关键词 Ciprofol clinical application application status Research progress
下载PDF
Data analysis guidelines for single‑cell RNA‑seq in biomedical studies and clinical applications
4
作者 Min Su Tao Pan +14 位作者 Qiu‑Zhen Chen Wei‑Wei Zhou Yi Gong Gang Xu Huan‑Yu Yan Si Li Qiao‑Zhen Shi Ya Zhang Xiao He Chun‑Jie Jiang Shi‑Cai Fan Xia Li Murray J.Cairns Xi Wang Yong‑Sheng Li 《Military Medical Research》 SCIE CAS CSCD 2023年第4期529-553,共25页
The application of single-cell RNA sequencing(scRNA-seq)in biomedical research has advanced our understanding of the pathogenesis of disease and provided valuable insights into new diagnostic and therapeutic strategie... The application of single-cell RNA sequencing(scRNA-seq)in biomedical research has advanced our understanding of the pathogenesis of disease and provided valuable insights into new diagnostic and therapeutic strategies.With the expansion of capacity for high-throughput scRNA-seq,including clinical samples,the analysis of these huge volumes of data has become a daunting prospect for researchers entering this field.Here,we review the workflow for typical scRNA-seq data analysis,covering raw data processing and quality control,basic data analysis applicable for almost all scRNA-seq data sets,and advanced data analysis that should be tailored to specific scientific questions.While summarizing the current methods for each analysis step,we also provide an online repository of software and wrapped-up scripts to support the implementation.Recommendations and caveats are pointed out for some specific analysis tasks and approaches.We hope this resource will be helpful to researchers engaging with scRNA-seq,in particular for emerging clinical applications. 展开更多
关键词 Single-cell RNA-sequencing(scRNA-seq) Data analysis Biomedical research clinical applications
下载PDF
Research Advances in Pharmacological Action and Clinical Application of Periplaneta americana 被引量:5
5
作者 罗廷顺 高孟婷 +2 位作者 马芳芳 刘光明 张成桂 《Agricultural Science & Technology》 CAS 2012年第4期888-892,共5页
Researches on pharmacological action and drug development of Periplane- ta americana have demonstrated that it has wide medicinal value, low side effects and rich resources, having good application prospects in medici... Researches on pharmacological action and drug development of Periplane- ta americana have demonstrated that it has wide medicinal value, low side effects and rich resources, having good application prospects in medicine field. This article reviewed the researches on pharmacological action and clinical application of Periplaneta americana in order to provide references for the further research and devel- opment of Periplaneta americana medicines. 展开更多
关键词 Periplaneta americana Inscet Pharmacological action clinical application
下载PDF
2017 Chinese expert consensus on the clinical application ofserum marker for thyroid cancer 被引量:4
6
作者 Ming Gao Minghua Ge +26 位作者 Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Wei Cui Li Gao Zairong Gao Lin Guo Zhuming Guo Tao Huang Xiaoming Huang Yansong Lin Qinjiang Liu Xin Ni Jianwu Qin Li Ren Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Bin Zhang DaiweiZhao Ying Zheng Jingqiang Zhu Xiangqian Zheng 《Cancer Biology & Medicine》 SCIE CAS CSCD 2018年第4期468-477,共10页
In recent years, the clinical incidence of thyroid cancer has been increasing year by year, and its risk assessment and clinical management methods have also been accordingly modified and constantly improved. There ar... In recent years, the clinical incidence of thyroid cancer has been increasing year by year, and its risk assessment and clinical management methods have also been accordingly modified and constantly improved. There are great differences between the clinical diagnostic and therapeutic modes and disease management of thyroid cancer employed by various medical institutions in China, particularly with regard to the clinical application of serum marker of thyroid cancer. To this end, the China Anti-Cancer Association Thyroid Cancer Specialized Committee Chinese Association of Thyroid Oncology organized this compilation of ExpertConsensus on Clinical Application of Serum Marker of Thyroid Cancer to help and impel relevant clinical institutions and professionals to standardize clinical diagnosis, treatment, and long-term management of thyroid cancer, and to properly utilize the serum marker for scientific auxiliary clinical diagnosis and assessment of thyroid cancer before and after operation. 展开更多
关键词 Chinese expert consensus on the clinical application of serum marker for thyroid cancer MTC TG
下载PDF
The Anatomical Physiology and Clinical Application of the Points Huiyang and Zhonglushu 被引量:3
7
作者 陈跃来 叶环 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第3期180-182,共3页
  Both Huiyang (BL 35) and Zhonglushu (BL 29) are the acupoints of the Bladder Meridian of Foot-Taiyang located in the sacral region. These two points are often used in combination to treat urinary dysfunction, and ...   Both Huiyang (BL 35) and Zhonglushu (BL 29) are the acupoints of the Bladder Meridian of Foot-Taiyang located in the sacral region. These two points are often used in combination to treat urinary dysfunction, and their regulatory effects are very satisfactory.1 In this article, the clinical mechanism of Huiyang and Zhonglushu is explained in accordance with the theory of Channels and neurophysiology.   …… 展开更多
关键词 BL In The Anatomical Physiology and clinical application of the Points Huiyang and Zhonglushu
下载PDF
Helicobacter pylori neutrophil-activating protein:From molecular pathogenesis to clinical applications 被引量:10
8
作者 Hua-Wen Fu 《World Journal of Gastroenterology》 SCIE CAS 2014年第18期5294-5301,共8页
Helicobacter pylori (H. pylori) neutrophil-activating protein (HP-NAP) was originally identified as a virulence factor of H. pylori for its ability to activate neutrophils to generate respiratory burst by releasing re... Helicobacter pylori (H. pylori) neutrophil-activating protein (HP-NAP) was originally identified as a virulence factor of H. pylori for its ability to activate neutrophils to generate respiratory burst by releasing reactive oxygen species. Later on, HP-NAP was also found to be involved in the protection of H. pylori from DNA damage, supporting the survival of H. pylori under oxidative stress. This protein is highly conserved and expressed by virtually all clinical isolates of H. pylori. The majority of patients infected with H. pylori produced antibodies specific for HP-NAP, suggesting its important role in immunity. In addition to acting as a pathogenic factor by activating the innate immunity through a wide range of human leukocytes, including neutrophils, monocytes, and mast cells, HP-NAP also mediates adaptive immunity through the induction of T helper cell type&#x02005;I&#x02005;responses. The pro-inflammatory and immunomodulatory properties of HP-NAP not only make it play an important role in disease pathogenesis but also make it a potential candidate for clinical use. Even though there is no convincing evidence to link HP-NAP to a disease outcome, recent findings supporting the pathogenic role of HP-NAP will be reviewed. In addition, the potential clinical applications of HP-NAP in vaccine development, clinical diagnosis, and drug development will be discussed. 展开更多
关键词 Helicobacter pylori Helicobacter pylori neutrophil-activating protein clinical application Vaccine Diagnosis Drug development Immunotherapy Immunomodulation T helper cell type  I/II
下载PDF
DNA typing of HLA by reverse PCRSSOP and clinical application
9
《中国输血杂志》 CAS CSCD 2001年第S1期371-,共1页
关键词 DNA typing of HLA by reverse PCRSSOP and clinical application HLA
下载PDF
THE CLINICAL APPLICATION OF VENTRICULAR ASSIST DEVICE
10
作者 屈根学 辛凌澎 +1 位作者 王怀军 王海新 《Academic Journal of Xi'an Jiaotong University》 2000年第1期87-89,共3页
关键词 OO THE clinical application OF VENTRICULAR ASSIST DEVICE
下载PDF
MEDICINAL VESICULATION THERAPY AND ITS CLINICAL APPLICATION
11
作者 王伟 刘海静 孙占玲 《World Journal of Acupuncture-Moxibustion》 2002年第4期33-36,共4页
In this paper, the authors introduce medicinal vesiculation therapy from its origin, points for attention in clinical application, and their individual experiences. In clinical application, the authors advocate: ① av... In this paper, the authors introduce medicinal vesiculation therapy from its origin, points for attention in clinical application, and their individual experiences. In clinical application, the authors advocate: ① avoid using drugs that are over-irritating in the property, and strictly controlling the dose of drugs and the duration of application, ② in selection of drugs, some factors as patients’ conditions, the season, the geographic location, etc. should be taken into account. In the present paper, 3 typical cases of bronchial asthma, tonsil swelling and facial paralysis treated with medicinal vesiculation therapy are introduced. Clinical practice demonstrates that this therapy is economical, simple and convenient and fairly effective in treatment of some chronic diseases. 展开更多
关键词 Medicinal vesiculation therapy clinical application
下载PDF
ACUPOINT TO ACUPOINT PENETRATIVE NEEDLING AND ITS CLINICAL APPLICATION
12
作者 汪洪明 《World Journal of Acupuncture-Moxibustion》 2001年第1期23-26,共4页
Acupoint to acupoint penetrative needling method has a long history in traditional Chinese medicine. Chinese physicians in various dynasties hold that this type of needling method can strengthen the needling sensation... Acupoint to acupoint penetrative needling method has a long history in traditional Chinese medicine. Chinese physicians in various dynasties hold that this type of needling method can strengthen the needling sensations and raise the therapeutic effect in clinical practice. This needling method can be divided into straight penetration, oblique penetration and transverse penetration. In clinical application, it can also be divided into external medial meridian penetration, a single meridian penetration, neighboring meridians penetration, and neighboring acupoints penetration, etc. in accordance with the involved acupoints and meridians. Clinical practice demonstrates that penetrative needling possesses advantages of stronger needling sensations, better therapeutic effect and fewer acupoints selection. For this reason, it is extensively applied in clinic. 展开更多
关键词 Acupoint to acupoint penetrative needling clinical application
下载PDF
Discuss on the Clinical Application of Yao Shu Acupoint
13
作者 Kang Duanqi Zhou Yuan(The Fifth Municipal Hospital,Shanghai 200240) 《中国针灸》 CAS CSCD 北大核心 1995年第S2期376-376,共1页
DiscussontheClinicalApplicationofYaoShuAcupoint¥KangDuanqi;ZhouYuan(TheFifthMunicipalHospital,Shanghai200240... DiscussontheClinicalApplicationofYaoShuAcupoint¥KangDuanqi;ZhouYuan(TheFifthMunicipalHospital,Shanghai200240)The"YaoShu"acupo... 展开更多
关键词 Discuss on the clinical application of Yao Shu Acupoint
下载PDF
EXAMPLES OF CLINICAL APPLICATION OF ACUPUNCTURE OF ZHONGWAN(CV12) WITH ELONGATED NEEDLE
14
作者 吴建华 阎莉 《World Journal of Acupuncture-Moxibustion》 2005年第1期43-45,共3页
In the present paper, the authors in troduce Professor YAN Li’s experie nce on clinical application of elongated needle for the treatment of gastralgia, migraine and hysteria by acupuncture of Zhongwan (中脘 CV 12). ... In the present paper, the authors in troduce Professor YAN Li’s experie nce on clinical application of elongated needle for the treatment of gastralgia, migraine and hysteria by acupuncture of Zhongwan (中脘 CV 12). In addition, the y also introduce its operation methods and some points for attention. During ope ration of the elongated needle, the operator should manipulate it gently, avoidi ng rude insertion and rash withdrawal; rather, utilize the elasticity of the steel wire to press the needle downward slowly, and cause the favorable needlin g sensations to spread slowly downward to the affected region along with the mov ement of the needle body. 展开更多
关键词 Elongated needle clinical application Gastralgia Migr aine Hysteria
下载PDF
Regulations governing clinical application of human organ transplant in China
15
《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2006年第2期316-316,共1页
To regulate human organ transplant, guarantee the quality and safety of the operation, protect the health of the people, the Health Ministry of China issued Regulations governing Clinical Application of Human Organ Tr... To regulate human organ transplant, guarantee the quality and safety of the operation, protect the health of the people, the Health Ministry of China issued Regulations governing Clinical Application of Human Organ Transplant on March 27, 2006, which is to be put into effect on the coming July 1. The regulations contain 5 chapters and 47 articles including general principles, registration of diagnosis and treatment, clinical management, supervision, and supplementary items. 展开更多
关键词 Regulations governing clinical application of human organ transplant in China
下载PDF
Preparation and clinical application of fibrin glue from human bloods
16
《中国输血杂志》 CAS CSCD 2001年第S1期423-,共1页
关键词 Preparation and clinical application of fibrin glue from human bloods
下载PDF
The clinical application review of apheresis platelet concentrates in Guangzhou from 1995~2000
17
《中国输血杂志》 CAS CSCD 2001年第S1期392-,共1页
关键词 The clinical application review of apheresis platelet concentrates in Guangzhou from 1995
下载PDF
China Association of Chinese Medicine Paper notice for seminar on clinical application of new technology of integrated Chinese and western medicine in treating sequelae of cerebrovascular diseases 被引量:1
18
作者 Academic Department of China Association of Chinese Medicine 《World Journal of Integrated Traditional and Western Medicine》 2018年第1期49-49,共1页
Hosted by ChinaAssociation of Chinese Medicine,and organized by World Journal of Integrated traditional and western Medicine,seminar on clinical application of new technology of integrated Chinese and western medicine... Hosted by ChinaAssociation of Chinese Medicine,and organized by World Journal of Integrated traditional and western Medicine,seminar on clinical application of new technology of integrated Chinese and western medicine in treating sequelae of cerebrovascular diseases is planned to be held in Nanning,Guangxi in August. 展开更多
关键词 China Association of Chinese Medicine Paper notice for seminar on clinical application of new technology of integrated Chinese and western medicine in treating sequelae of cerebrovascular diseases
下载PDF
X-ray photon counting detectors for preclinical and clinical applications
19
作者 REN Liqiang LIU Hong 《Instrumentation》 2016年第4期43-54,共12页
Photon counting detectors(PCDs) have attained w ide use in X-ray imaging for various preclinical and clinical applications in the past decade. This paper briefly review s the preclinical and clinical applications of P... Photon counting detectors(PCDs) have attained w ide use in X-ray imaging for various preclinical and clinical applications in the past decade. This paper briefly review s the preclinical and clinical applications of PCDs based X-ray imaging systems.Starting with an introduction of X-ray single photon detection mechanism,the brief review first describes tw o major advantages of utilizing PCDs: photon energy resolving capability and electronic noise elimination. Compared to energy integrating detectors(EIDs),the aforementioned advantages make PCDs more favorable in X-ray imaging with profound benefits such as enhanced tissue contrast,decreased image noise,increased signal to noise ratio,decreased radiation dose to the small animals and patients,and more accurate material decomposition. The utilizations of PCDs in X-ray projection radiography and computed tomography(CT)including micro-CT,dedicated breast CT,K-edge CT,and clinical CT are then review ed for the imaging applications ranging from phantoms to small animals and humans. In addition,optimization methods aiming to improve the imaging performance using PCDs are briefly review ed. PCDs are not flaw less though,and their limitations are also discussed in this review. Nevertheless,PCDs may continuously contribute to the advancement of X-ray imaging techniques in future preclinical and clinical applications. 展开更多
关键词 Photon counting detectors(PCDs) energy integrating detectors(EIDs) X-ray imaging systems preclinical and clinical application
下载PDF
A Preliminary Study and Modern Clinical Application of the Theory of“Fu Qing Zhu Nu Ke”in the Treatment of Metrorrhagia and Metrostaxis
20
作者 Yao Yuan Tao Ba +1 位作者 Yu Chun Qian Jing Cai 《Journal of Clinical and Nursing Research》 2022年第4期35-41,共7页
“Fu Qing Zhu Nu Ke”specially set seven chapters for metrorrhagia,where Fu’s treatment of metrorrhagia emphasizes the treatment of the root cause of the metrorrhagia,invisible blood hemostasis,attention to the appli... “Fu Qing Zhu Nu Ke”specially set seven chapters for metrorrhagia,where Fu’s treatment of metrorrhagia emphasizes the treatment of the root cause of the metrorrhagia,invisible blood hemostasis,attention to the application of drugs for supplementing qi,blood,liver and kidney,medication with sweet,mild,and gentle properties,and repeatedly emphasized the influence of sexual affairs on gynecological diseases.Modern doctors have applied this prescription in clinical treatment of metrorrhagia.In this paper,the author makes a preliminary discussion and analysis of Fu’s thought of stopping metrorrhagia,and summarizes its modern clinical application and expansion,to enrich clinical experience and serve the patients better. 展开更多
关键词 Fu Qing Zhu Nu Ke METRORRHAGIA METROSTAXIS THEORY Modern clinical application
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部