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Therapeutic Effects of Integrated Traditional Chinese Medicine and Western Medicine in Treating Severe Acute Respiratory Syndrome 被引量:2
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作者 王融冰 刘军民 +5 位作者 江宇泳 吴云忠 王晓静 池频频 孙凤霞 高连印 《Chinese Journal of Integrated Traditional and Western Medicine》 2003年第4期259-262,共4页
Objective: To improve the effects of treatment of severe acute re spiratory syndrome (SARS) and to explore the clinical significance of integrate d traditional Chinese medicine and western medicine (ICWM) in the treat... Objective: To improve the effects of treatment of severe acute re spiratory syndrome (SARS) and to explore the clinical significance of integrate d traditional Chinese medicine and western medicine (ICWM) in the treatment of S ARS and its influence on the chief indexes in the process of the disease. Methods: The clinical study involving observation of 135 patients of SARS was conducted in the randomized, synchronously controlled and open way. The patients were divided into two groups, 68 in the ICWM group and 67 in the c ontrol group, all of whom were treated with the same basic treatment of western medicine, but to the ICWM group, Chinese drugs for clearing Heat, detoxifying an d removing Dampness were given additionally. The comprehensive effect on relievi ng fever, cell mediated immunity, pulmonary inflammation and secondary infect ion was compared between the two groups. Results: The therapeutic effect in the ICWM group was better than that in the control group in such aspects as steadily lowering body temperature, alleviating general symptoms, accelerating the absorption of pulmonary infiltra tion and easing cellular immunity suppression. Conclusion: The therapeutic effect of ICWM is better in treating SARS than that of western medicine alone. 展开更多
关键词 integrated traditional chinese and weste rn medicinal therapy severe acute respiratory syndrome synchronous controlled study
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Analysis on the therapeutic effects of integrated traditional Chinese and Western medicine on ulcerative colitis and its effects on coagulation function and inflammatory factors
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作者 Qiong Wang Han-Ting Zhu +1 位作者 Guo-Rong Wu Wen Chen 《Journal of Hainan Medical University》 2019年第1期5-9,共5页
Objective:To analyze the therapeutic effects of Integrated Traditional Chinese and Western Medicine on ulcerative colitis (UC) and its effects on coagulation function and inflammatory factors.Methods: 220 cases of pat... Objective:To analyze the therapeutic effects of Integrated Traditional Chinese and Western Medicine on ulcerative colitis (UC) and its effects on coagulation function and inflammatory factors.Methods: 220 cases of patients with UC were selected as the research subjects and randomly divided into the observation group and the control group, 110 cases were included into each group. The patients in the control group were treated with single western medicine, while the patients in the observation group were treated with enema treatment of traditional Chinese Medicine. The clinical therapeutic effects of the two groups were evaluated and compared. The blood coagulation indexes of the activated partial thromboplastin time (APTT), prothrombin time (PT), the plasma fibrinogen (Fib), the D dimer (D-D) of two groups patients who in the treatment were detected and compared. The serum tumor necrosis factor (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8) levels of the patients in the two groups were measured and compared.Results: The clinical efficiencies of the observation group and the control group were 97% and 75%, the clinical efficiencies and the therapeutic effects of the observation group were better than those in the control group, there were statistically significant differences between the two groups. The plasma Fib levels and the plasma D-D levels after the treatment of the patients in the two groups were significantly lower than those before the treatment, the difference was statistically significant. The plasma Fib levels and the plasma D-D levels after the treatment of the patients in the observation group were lower than those in the control group, the difference was statistically significant. The serum inflammatory factors levels after the treatment of the patients in the two groups were significantly lower than those before the treatment, the difference was statistically significant. The serum inflammatory factors levels after the treatment of the patients in the observation group were lower than those in the control group, the difference is powerful and have statistically significant.Conclusion: The application of Integrated Traditional Chinese and Western Medicine in the treatment of UC can improve the therapeutic effect significantly, correct imbalance of the patients' coagulation dissolution function, reduce the degree of inflammatory reaction, which benefits to promote of the patients' rehabilitation, reduce the incidence of complications and improve the prognosis of patients. 展开更多
关键词 integrated chinese and Western Medicine ULCERATIVE COLITIS Experimental therapy COAGULATION and FIBRINOLYSIS Inflammatory factor
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A Survey on Treatment of Dry Eye by Traditional Chinese Medicine and Integrative Chinese and Western Medicine 被引量:2
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作者 周婉瑜 李越虹 《Chinese Journal of Integrated Traditional and Western Medicine》 2006年第2期154-159,共6页
Dry eye is now one of the most common superficial disorders in ophthalmology at home and abroad, and more and more people attach importance to the study. The ideal approach for treatment of dry eye is to normalize the... Dry eye is now one of the most common superficial disorders in ophthalmology at home and abroad, and more and more people attach importance to the study. The ideal approach for treatment of dry eye is to normalize the condition by rebuilding the superficial circumstance of the eye, and to make tear film work as well as possible so as to relieve the irritating symptoms in the eye. The authors are making a comprehensive discussion on the methods and curative effects of treating dry eye by traditional Chinese medicine and by integrative Chinese and Western medicine in recent years, so as to introduce the distinctive features of the traditional Chinese medicine and integrative Chinese and Western medicine in this field. 展开更多
关键词 dry eye traditional chinese medicine therapy integrative chinese and Western medicine therapy
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Clinical Evaluation of Integrative Chinese and Western Medicine in Treating SARS 被引量:2
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作者 李秀惠 张可 +4 位作者 胡建华 郭新会 胡中杰 杨宇 梁连春 《Chinese Journal of Integrated Traditional and Western Medicine》 2003年第3期181-184,共4页
Objective:To evaluate the effective treatment with integrative Chinese and western medicine (ICWM) of severe acute respiratory syndrome (SARS). Methods: The 65 cases of SARS patients were treated with ICWM and 37 case... Objective:To evaluate the effective treatment with integrative Chinese and western medicine (ICWM) of severe acute respiratory syndrome (SARS). Methods: The 65 cases of SARS patients were treated with ICWM and 37 cases with western medicine (WM) alone as the control in our hospital from March 11 to April 30, 2003. The results were analyzed, with T subset profile tested for all the 102 patients. Results: Sixty-five cases of SARS patients treated with ICWM included 52 mild cases of whom 51 cases were cured (98.1%) and no patient died. As to the 13 severe cases in this group, 9 were cured (69. 2%) and 2 died (15. 4%). Of the 37 cases treated with WM alone, 16 out of the 18 common cases were cured (88. 9%) and 10 out of the 19 severe cases were cured (52. 6%), with the other 9 died (47. 4%). Comparison between the two groups (P=0. 061) showed the difference was close to the value for statistical significance. But considering that the number of samples was small, more cases are needed for further study. The immune function examination: in cases of the common type, after ICWM treatment, CD4 + T lymphocytes were increased from 360±247 cell/mm3 to 563±479 cell/mm3 (P<0. 05). In the group treated with WM alone, CD4+ T lymphocytes were increased from 331 ±193 cell/mm3 to 772±354 cell/mm3 (P<0. 05). As to the severe cases after ICWM treatment, CD4+ T lymphocytes increased from 352±279 cell/mm3 to 525±490 cell/mm3 (P>0. 05). In the group of severe cases treated with WM alone, CD4+ T lymphocytes reduced from 229±69 cell/mm3 to 205±108 cell/mm3 (P>0. 05). While after ICWM treatment, CD4+ T lymphocytes were significantly higher than that of the group treated with WM alone (P< 0. 05). Conclusion: Compared with the group treated with WM alone, ICWM can significantly improve the prognosis, reduce the mortality as well as improve the immune function of SARS patients. 展开更多
关键词 integrative chinese and western medicine severe acute respiratory syndrome therapy T lymphocyte subsets
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半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病肝胃郁热证疗效及安全性 被引量:1
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作者 陈丽 张江春 +1 位作者 郭洁 万媛 《河北中医》 2024年第9期1455-1459,共5页
目的观察半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病(NERD)肝胃郁热证的疗效及安全性。方法选择NERD肝胃郁热证患者98例,按随机数字表法分为2组,对照组(n=49)予艾司奥美拉唑镁肠溶片,治疗组(n=49)在对照组基础上... 目的观察半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗非糜烂性胃食管反流病(NERD)肝胃郁热证的疗效及安全性。方法选择NERD肝胃郁热证患者98例,按随机数字表法分为2组,对照组(n=49)予艾司奥美拉唑镁肠溶片,治疗组(n=49)在对照组基础上辅以半夏泻心汤加减,连续治疗8周。比较2组疗效及治疗前后中医证候总积分、食管动力[下食管括约肌静息压(LESP)、上食管括约肌静息压(UESP)]、胃肠激素[胃动素、胃泌素、胃促生长素(Ghrelin)、血管活性肠肽(VIP)]、汉密尔顿抑郁量表-17(HAMD-17)评分变化,并观察2组治疗期间不良反应发生情况。结果治疗组总有效率为95.92%(47/49),对照组为73.47%(36/49),治疗组临床疗效优于对照组(P<0.05)。2组治疗后中医证候总积分、HAMD-17评分均较本组治疗前降低(P<0.05),且治疗组均低于对照组(P<0.05)。2组治疗后LESP均较本组治疗前升高(P<0.05),UESP均较本组治疗前降低(P<0.05);治疗后治疗组LESP高于对照组(P<0.05),UESP低于对照组(P<0.05)。2组治疗后胃动素、胃泌素、Ghrelin均较本组治疗前升高(P<0.05),VIP均较本组治疗前降低(P<0.05);治疗后治疗组胃动素、胃泌素、Ghrelin高于对照组(P<0.05),VIP低于对照组(P<0.05)。2组治疗期间均未发生不良反应。结论半夏泻心汤加减联合艾司奥美拉唑镁肠溶片治疗NERD肝胃郁热证疗效肯定,能改善食管动力及抑郁状态,调节胃肠激素,且安全性高。 展开更多
关键词 胃食管反流 中西医结合疗法
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Advances in the management of arteriosclerosis of the lower extremity:Integrating Western and Chinese medicine approaches
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作者 Sha Cheng Jia-Xin Xu Wen-Jie Long 《World Journal of Clinical Cases》 SCIE 2024年第36期6871-6876,共6页
This editorial provides a commentary on the recent article.The paper reviews current literature and explores innovative treatment strategies for lower extremity arteriosclerosis obliterans(LEASO)through an integrative... This editorial provides a commentary on the recent article.The paper reviews current literature and explores innovative treatment strategies for lower extremity arteriosclerosis obliterans(LEASO)through an integrative approach.It highlights the effectiveness of combination therapies that merge traditional Chinese medicine(TCM)with Western medical practices,suggesting that such integrative methods may improve patient compliance and outcomes through personalized care.This paper stresses the importance of rigorous clinical trials to evaluate the efficacy and safety of TCM interventions within LEASO treatment protocols,advocating for evidence-based validation of these combined therapies.Our recommendations emphasize accurate diagnosis,appropriate pharmacological in-terventions,the use of advanced surgical and endovascular techniques,and the inclusion of TCM to address underlying dysfunctions.Additionally,continuous monitoring,patient education,and lifestyle modifications are essential to slow disease progression and achieve optimal patient outcomes.The paper concludes by calling for further research to develop standardized treatment protocols that effectively integrate both Western and Chinese medical approaches in managing LEASO. 展开更多
关键词 Lower extremity arteriosclerosis obliterans Traditional chinese medicine integrative healthcare Vascular therapy Combination therapies
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异位妊娠中西医结合保守治疗的现状和展望 被引量:1
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作者 纪诚 陈雪 +1 位作者 叶聪 杨依玲 《长春中医药大学学报》 2024年第3期340-344,共5页
异位妊娠作为一种常见的妇科急症,其治疗策略的优化对于提升育龄女性生殖健康具有重要意义。该文综合分析了中西医结合在异位妊娠保守治疗中的应用现状,并探讨了其未来发展趋势。通过对甲氨蝶呤单药治疗和腹腔镜手术等西医传统方法的评... 异位妊娠作为一种常见的妇科急症,其治疗策略的优化对于提升育龄女性生殖健康具有重要意义。该文综合分析了中西医结合在异位妊娠保守治疗中的应用现状,并探讨了其未来发展趋势。通过对甲氨蝶呤单药治疗和腹腔镜手术等西医传统方法的评估,与中医药治疗如中药、针灸和推拿等方法的综合疗效进行对比,揭示了中西医结合治疗在提高治疗效果和降低副作用方面的潜力。展望未来,个体化治疗方案、微创技术的进步和中药新药的开发,预计将为异位妊娠的保守治疗提供更广阔的视野。本综述强调了中西医结合治疗异位妊娠的优势,并为其在临床实践中的深入应用提供了科学依据。 展开更多
关键词 异位妊娠 中西医结合 保守治疗 药物治疗 针灸疗法 手术治疗
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身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征的临床观察 被引量:1
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作者 杜青 宁倩 +5 位作者 徐栋 李鑫 顾宝东 王英超 马先军 赵晓慧 《河北中医》 2024年第1期25-28,共4页
目的观察身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征(RLS)患者的临床疗效。方法将50名痰瘀痹阻型RLS患者按照随机数字表法分为2组,对照组25例予盐酸普拉克索片治疗,治疗组25例在对照组基础上联合身痛逐瘀汤加味治疗。... 目的观察身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型不宁腿综合征(RLS)患者的临床疗效。方法将50名痰瘀痹阻型RLS患者按照随机数字表法分为2组,对照组25例予盐酸普拉克索片治疗,治疗组25例在对照组基础上联合身痛逐瘀汤加味治疗。2组均治疗1周为1个疗程,治疗2个疗程后统计疗效,比较2组治疗前后国际RLS严重程度评分量表(IRLS)评分、匹兹堡睡眠质量指数量表(PSQI)评分及中医症状评分变化情况。结果治疗组总有效率92.00%(23/25),对照组总有效率60.00%(15/25),治疗组总有效率高于对照组(P<0.05)。与本组治疗前比较,2组治疗后IRLS评分、PSQI评分及中医症状评分均降低(P<0.05),且治疗组治疗后IRLS评分、PSQI评分及中医症状评分均低于对照组(P<0.05)。结论身痛逐瘀汤加味联合盐酸普拉克索片治疗痰瘀痹阻型RLS疗效确切,可有效改善患者临床症状及中医症状,改善患者睡眠质量,操作简便,临床疗效显著,安全性良好。 展开更多
关键词 不宁腿综合征 普拉克索 身痛逐瘀汤 痰瘀痹阻 中西医结合疗法
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扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床研究 被引量:1
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作者 刘兴国 聂晨 +3 位作者 付明洁 曹繁华 杜冬琛 冯定华 《河北中医》 2024年第1期51-55,共5页
目的观察扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床疗效。方法将108例复发性尿路感染患者按照随机数字表方法分为3组,中药组36例予扶正通淋散治疗,西药组36例予临床常规西医治疗,联合组36例予扶正通淋散联合临床常规西医... 目的观察扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染的临床疗效。方法将108例复发性尿路感染患者按照随机数字表方法分为3组,中药组36例予扶正通淋散治疗,西药组36例予临床常规西医治疗,联合组36例予扶正通淋散联合临床常规西医治疗。3组均治疗3个月,随访6个月。比较3组治疗前后尿常规[白细胞计数(WBC)、红细胞计数(RBC)]、尿细菌培养结果、血清炎症相关指标[肿瘤坏死因子α(TNF-α)、降钙素原(PCT)、白细胞介素6(IL-6)],治疗前及治疗结束后1个月健康调查简表(SF-36)评分,并统计临床疗效及复发率。结果联合组总有效率91.67%(33/36),中药组总有效率72.22%(26/36),西药组总有效率66.67%(24/36),联合组疗效优于中药组、西药组(P<0.05)。3组治疗后尿常规WBC、RBC均较本组治疗前降低(P<0.05),且联合组治疗后均低于中药组、西药组(P<0.05),中药组均低于西药组(P<0.05)。3组治疗后血清TNF-α、PCT、IL-6水平均较本组治疗前降低(P<0.05),且联合组治疗后均低于中药组、西药组(P<0.05),中药组均低于西药组(P<0.05)。3组治疗后SF-36量表各维度评分均较本组治疗前升高(P<0.05),且联合组均高于中药组、西药组(P<0.05)。联合组尿路感染复发率显著低于中药组、西药组(P<0.05)。结论扶正通淋散治疗脾肾两虚湿热内蕴型复发性尿路感染有较好疗效,可以显著改善患者炎症水平和生活质量,降低复发率。 展开更多
关键词 复发性尿路感染 中西医结合疗法
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解痉汤联合地佐辛注射液治疗自发性蛛网膜下腔出血的疗效及对血清可溶性血管内皮生长因子受体-1、可溶性细胞间黏附分子-1的影响
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作者 丁奇 高永荣 +4 位作者 刘熙鹏 曹兵 张艺 王鹏飞 乔建新 《河北中医》 2024年第7期1102-1106,共5页
目的观察解痉汤联合地佐辛注射液治疗自发性蛛网膜下腔出血(SAH)的疗效及对血清可溶性血管内皮生长因子受体-1(sFlt-1)、可溶性细胞间黏附分子-1(sICAM-1)的影响。方法将88例SAH患者按照随机数字表法分为2组,对照组44例予地佐辛注射液治... 目的观察解痉汤联合地佐辛注射液治疗自发性蛛网膜下腔出血(SAH)的疗效及对血清可溶性血管内皮生长因子受体-1(sFlt-1)、可溶性细胞间黏附分子-1(sICAM-1)的影响。方法将88例SAH患者按照随机数字表法分为2组,对照组44例予地佐辛注射液治疗,治疗组44例在对照组治疗基础上加解痉汤治疗,2组均治疗14天。比较2组疗效;比较2组治疗前、治疗7天、治疗后大脑中动脉平均血流速度(MBF)、脑血管痉挛发生情况;比较2组治疗前后氧化应激指标变化;比较2组治疗前后血管内皮损伤因子水平;比较2组治疗前后美国国立卫生研究院卒中量表(NIHSS)、格拉斯哥昏迷量表(GCS)、简易智力状态检查量表(MMSE)评分;比较2组不良反应发生率。结果治疗组总有效率95.45%(42/44),对照组总有效率79.55%(35/44),治疗组疗效优于对照组(P<0.05)。治疗组治疗7天、治疗后MBF、脑血管痉挛发生率均低于对照组治疗同期(P<0.05)。2组治疗后血清还原型谷胱甘肽(GSH)、超氧化物歧化酶(SOD)水平均较本组治疗前升高(P<0.05),丙二醛(MDA)水平较本组治疗前降低(P<0.05);治疗后治疗组血清GSH、SOD水平均高于对照组(P<0.05),MDA水平低于对照组(P<0.05)。2组治疗后血清sFlt-1、sICAM-1水平均较本组治疗前降低(P<0.05),且治疗组降低更明显(P<0.05)。2组治疗后NIHSS评分均较本组治疗前降低(P<0.05),GCS、MMSE评分均较本组治疗前升高(P<0.05);治疗后治疗组NIHSS评分低于对照组(P<0.05),GCS、MMSE评分均高于对照组(P<0.05)。2组不良反应发生率比较差异无统计学意义(P>0.05)。结论解痉汤联合地佐辛注射液治疗SAH,能降低脑血管痉挛发生率,改善患者脑部血流、氧化应激及血管内皮损伤,促进神经功能恢复。 展开更多
关键词 蛛网膜下腔出血 中药疗法 中西医结合疗法
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耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛临床观察 被引量:2
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作者 于涓 《中国中医药现代远程教育》 2024年第12期136-138,共3页
目的分析耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛(PHN)的临床效果。方法经随机方式把80例带状疱疹(HZ)住院患者归入对照组、治疗组,分别实施常规治护+普瑞巴林胶囊口服止痛疗法、常规治护+中医耳穴压豆+普瑞巴林胶... 目的分析耳穴疗法联合普瑞巴林胶囊治疗气滞血瘀型带状疱疹后遗神经痛(PHN)的临床效果。方法经随机方式把80例带状疱疹(HZ)住院患者归入对照组、治疗组,分别实施常规治护+普瑞巴林胶囊口服止痛疗法、常规治护+中医耳穴压豆+普瑞巴林胶囊口服止痛疗法,对比两组神经痛改善状况。结果在疼痛缓解方面,相较对照组,治疗组具有显著优势(P<0.05)。治疗组总有效率为90.00%(36/40),高于对照组的77.50%(31/40);治疗组的复发率为10.00%(4/40),低于对照组的22.50%(9/40)(P<0.05)。结论耳穴压豆+普瑞巴林胶囊疗法对于气滞血瘀型PHN的缓解有着积极作用,同时止痛效果相较单用普瑞巴林胶囊更具优势。 展开更多
关键词 蛇串疮 带状疱疹后遗神经痛 气滞血瘀证 耳穴压豆疗法 普瑞巴林 中西医结合疗法
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中西医结合法治疗小儿阑尾周围脓肿的疗效
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作者 刘瑜 王城 +3 位作者 周柯均 邓琳 郑蕾 蒲娟 《川北医学院学报》 CAS 2024年第6期807-810,共4页
目的:探究中西医结合法治疗小儿阑尾周围脓肿的临床疗效。方法:选取161例阑尾周围脓肿患儿作为研究对象,根据不同治疗方案分为西医组(n=82)及中西医结合组(n=79)。西医组患儿予以西医常规治疗;中西医结合组在西医组治疗的基础上应用中... 目的:探究中西医结合法治疗小儿阑尾周围脓肿的临床疗效。方法:选取161例阑尾周围脓肿患儿作为研究对象,根据不同治疗方案分为西医组(n=82)及中西医结合组(n=79)。西医组患儿予以西医常规治疗;中西医结合组在西医组治疗的基础上应用中药外敷治疗。比较两组患儿的临床疗效、不同时间点空腹静脉血中白细胞(WBC)、C-反应蛋白(CRP)及腹腔脓肿直径的变化情况。结果:中西医结合组的总体有效率为89.87%,高于西医组的71.95%(P<0.05)。治疗3、7、14 d后,两组WBC均降低,且中西医结合组低于西医组(P<0.05);治疗3、7、14 d后,两组CRP均降低,且治疗7、14 d后中西医结合组低于西医组(P<0.05)。中西医结合组腹腔脓肿直径小于西医组(P<0.05)。结论:中西医结合治疗小儿阑尾周围脓肿较常规的西医治疗更加有效,安全性高,值得在临床推广。 展开更多
关键词 儿童阑尾脓肿 中西医结合疗法 外敷
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复方丹参滴丸联合雷米普利片对糖尿病肾病患者肾功能、P选择素水平及糖脂代谢的影响
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作者 黄秀丽 吴艳 +2 位作者 付彩雯 喻荷淋 周艳君 《河北中医》 2024年第5期713-716,721,共5页
目的观察复方丹参滴丸联合雷米普利片对糖尿病肾病(DN)患者肾功能、P选择素水平及糖脂代谢的影响。方法将88例DN患者按照随机数字表法分为2组,对照组44例予雷米普利片治疗,治疗组44例在对照组治疗基础上予复方丹参滴丸治疗。2组均治疗4... 目的观察复方丹参滴丸联合雷米普利片对糖尿病肾病(DN)患者肾功能、P选择素水平及糖脂代谢的影响。方法将88例DN患者按照随机数字表法分为2组,对照组44例予雷米普利片治疗,治疗组44例在对照组治疗基础上予复方丹参滴丸治疗。2组均治疗4周。比较2组治疗前后中医证候评分、肾功能[血尿素氮(BUN)、血肌酐(SCr)及尿蛋白排泄率]、糖脂代谢[餐后2 h血糖(2 hPG)、空腹血糖(FPG)、甘油三酯(TG)、总胆固醇(TC)]、炎症因子[超敏C反应蛋白(hs-CRP)、P选择素、肿瘤坏死因子α(TNF-α)]水平及不良反应发生率。结果2组治疗后中医证候各项评分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后BUN、SCr、尿蛋白排泄率均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后FPG、2 hPG、TG、TC水平均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后血清hs-CRP、P选择素、TNF-α水平均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。治疗组不良反应发生率11.36%(5/44),对照组不良反应发生率4.55%(2/44),2组比较差异无统计学意义(P>0.05)。结论复方丹参滴丸联合雷米普利片治疗DN可有效提高肾功能,改善糖脂代谢,减轻炎症反应,降低P选择素水平,安全有效。 展开更多
关键词 糖尿病肾病 中西医结合疗法
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二天养胎汤联合低分子量肝素治疗复发性自然流产血栓前状态的临床研究
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作者 向丽娟 戴海青 +2 位作者 戴小萍 曾根 周意 《河北中医》 2024年第10期1617-1622,共6页
目的观察二天养胎汤联合低分子量肝素对复发性自然流产(RSA)血栓前状态的治疗效果。方法选取2021年10月至2022年11月海南省中医院妇产科门诊就诊及住院的RSA血栓前状态早期妊娠,中医辨证为肾虚血瘀患者80例,采用随机数字法将符合纳入标... 目的观察二天养胎汤联合低分子量肝素对复发性自然流产(RSA)血栓前状态的治疗效果。方法选取2021年10月至2022年11月海南省中医院妇产科门诊就诊及住院的RSA血栓前状态早期妊娠,中医辨证为肾虚血瘀患者80例,采用随机数字法将符合纳入标准患者分为2组,二天养胎汤联合低分子量肝素治疗组(联合治疗组)和低分子量肝素治疗组(肝素治疗组)。其中肝素治疗组入院后给予患者脐周皮下注射低分子量肝素4100 U,每日1次,用药至孕12周。联合治疗组同期予中药二天养胎汤口服。观察各组患者用药前后的治疗效果、中医证候评分改善情况、凝血指标及生长因子和Rho相关卷曲螺旋形成蛋白激酶/LIM激酶1/丝切蛋白(ROCK/LIMK1/Cofilin)通路相关基因表达情况。结果联合治疗组与肝素治疗组相比,其总有效率及活产率均较高,差异有统计学意义(P<0.05)。2组患者治疗前,中医证候积分无明显差别(P>0.05);2组患者治疗后与治疗前相比中医证候积分均有改善(P<0.05),但联合治疗组与肝素治疗组相比,其中医证候评分较低,差异有统计学意义(P<0.05)。2组患者治疗前,各凝血指标无明显差别(P>0.05);联合治疗组治疗后与治疗前相比各凝血指标均有改善(P<0.05);肝素治疗组治疗后与治疗前相比,其纤维蛋白原(FIB)、D-二聚体(D-D)、抗凝血酶Ⅲ(ATⅢ)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)有改善(P<0.05)。联合治疗组与肝素治疗组相比,其凝血功能指标均有不同程度的改善,差异有统计学意义(P<0.05)。2组患者治疗前,孕激素及血清相关因子无明显差别(P>0.05);联合治疗组治疗后与治疗前相比各凝血指标均有改善(P<0.05);肝素治疗组治疗后与治疗前相比,其孕酮(P)、人绒毛膜促性腺激素(β-HCG)、一氧化氮(NO)、透明质酸(HA)、血管内皮生长因子A(VEGFA)、胰岛素样生长因子-1(IGF-1)、转化生长因子β1(TGF-β1)有改善(P<0.05)。联合治疗组与肝素治疗组相比,孕激素及血清相关因子均有不同程度的改善,差异有统计学意义(P<0.05)。联合治疗组与肝素治疗组相比,其ROCK、LIMK1表达有所升高(P<0.05),其中LIMK1升高最明显。结论二天养胎汤能够有效改善RSA血栓前状态患者的活产率,维持凝血功能的正常;除此作用外,还可以通过改善血清生长因子VEGFA、IGF-1、TGF-β1以及血管功能保护因子NO、HA调节血栓前状态RSA患者的血管生长及维持血管正常功能,而这些作用可能与二天养胎汤能够通过促进Cofilin的磷酸化激酶ROCK、LIMK1的表达相关。 展开更多
关键词 复发性流产 低分子量肝素 中西医结合疗法
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1例肾阳虚型高血压患者的“双心护理”体会
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作者 崔淑节 胡瑶瑶 +2 位作者 章玲群 徐蒙 任鹏娜 《中西医结合护理》 2024年第2期83-86,共4页
本文总结了1例肾阳虚型高血压患者的“双心护理”体会。护理要点包括病情观察、血压监测、用药护理、中医特色护理等,并在此基础上给予心理评估、“双心”教育等干预措施。基于“双心护理”模式开展中西医结合护理,有助于改善患者症状,... 本文总结了1例肾阳虚型高血压患者的“双心护理”体会。护理要点包括病情观察、血压监测、用药护理、中医特色护理等,并在此基础上给予心理评估、“双心”教育等干预措施。基于“双心护理”模式开展中西医结合护理,有助于改善患者症状,缓解心理压力,提高治疗依从性,促进患者康复。 展开更多
关键词 高血压 中西医结合护理 刮痧 艾灸 认知行为干预 双心护理
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石建华中西医结合治疗甲状腺结节治法经验
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作者 赵琳 石建华 翟丽娜 《长春中医药大学学报》 2024年第10期1091-1094,共4页
石建华教授治疗甲状腺结节积累着丰富的临床经验。石建华认为,甲状腺结节的病机核心在于气血瘀滞,因此,治疗的关键在于调和气血。在临床实践中,他根据患者的具体病情,灵活采用药物治疗或手术治疗,并创新性地将中西医结合,以期达到最佳... 石建华教授治疗甲状腺结节积累着丰富的临床经验。石建华认为,甲状腺结节的病机核心在于气血瘀滞,因此,治疗的关键在于调和气血。在临床实践中,他根据患者的具体病情,灵活采用药物治疗或手术治疗,并创新性地将中西医结合,以期达到最佳治疗效果。在用药方面,其善于运用中药化瘀散结,同时结合西药调节内分泌,旨在全面改善患者病情,提高其生活质量。石建华坚持个体化治疗方案、注重整体调理与局部治疗并重的治疗原则,力求在根治疾病的同时,最大限度地提升患者的生活质量。 展开更多
关键词 甲状腺结节 中西医结合疗法 石建华
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清咳平喘颗粒对COPD急性加重期的临床疗效
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作者 李冬生 秦艺榕 +3 位作者 乔曼 迟航 崔青敏 李晓秋 《天津医药》 CAS 2024年第8期854-857,共4页
目的探讨清咳平喘颗粒对慢性阻塞性肺疾病急性加重期(AECOPD)患者临床疗效的影响。方法选取80例呼吸科住院治疗的AECOPD患者,其中常规组和联合组各40例,分别于治疗前、治疗第2周末、治疗1个月后观察2组患者自我评估测试(CAT)评分、疗效... 目的探讨清咳平喘颗粒对慢性阻塞性肺疾病急性加重期(AECOPD)患者临床疗效的影响。方法选取80例呼吸科住院治疗的AECOPD患者,其中常规组和联合组各40例,分别于治疗前、治疗第2周末、治疗1个月后观察2组患者自我评估测试(CAT)评分、疗效指数、白细胞介素(IL)-6水平、C-反应蛋白(CRP)水平、第1秒用力呼气容积(FEV1)/用力肺活量(FVC)、FEV1占预计值百分比(FEV1%pred)的差异。结果联合组总有效率高于常规组(92.5%vs.75.0%,P<0.05)。治疗第2周末,2组FEV1%pred、FEV1/FVC、IL-6水平、CRP水平与治疗前比较均有所改善,且联合组改善程度优于常规组(P<0.05),2组患者呼吸衰竭比例均较治疗前明显好转;随访1个月,联合组CAT评分回弹率低于常规组(P<0.05);2组不良反应发生率差异无统计学意义(12.5%vs.2.5%,P>0.05)。结论清咳平喘颗粒能有效改善AECOPD患者的临床症状及肺功能,提高生活质量。 展开更多
关键词 肺疾病 慢性阻塞性 痰浊阻肺 中西医结合疗法 清咳平喘颗粒
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柴胡加龙骨牡蛎汤联合艾司西酞普兰对卒中后抑郁患者神经功能、抑郁状态和血清脑源性神经营养因子、5-羟色胺水平的影响
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作者 凌志香 张兰坤 刘元月 《河北中医》 2024年第9期1472-1474,1479,共4页
目的观察柴胡加龙骨牡蛎汤联合艾司西酞普兰对卒中后抑郁(PSD)患者神经功能、抑郁状态及血清脑源性神经营养因子(BDNF)、5-羟色胺(5-HT)水平的影响。方法将98例PSD患者按照随机数字表法分为治疗组和对照组,各49例。对照组予草酸艾司西... 目的观察柴胡加龙骨牡蛎汤联合艾司西酞普兰对卒中后抑郁(PSD)患者神经功能、抑郁状态及血清脑源性神经营养因子(BDNF)、5-羟色胺(5-HT)水平的影响。方法将98例PSD患者按照随机数字表法分为治疗组和对照组,各49例。对照组予草酸艾司西酞普兰片治疗6周,治疗组在对照组治疗基础上加柴胡加龙骨牡蛎汤治疗6周。比较2组疗效及治疗前、治疗3周和治疗6周美国国立卫生研究院卒中量表(NIHSS)评分和血清5-HT、BDNF水平。结果治疗组总有效率87.76%(43/49),对照组总有效率69.39%(34/49),治疗组总有效率高于对照组(P<0.05)。2组治疗3、6周NIHSS、HAMD评分均显著低于本组治疗前(P<0.05),治疗6周NIHSS和HAMD评分均显著低于本组治疗3周(P<0.05);治疗3、6周治疗组NIHSS和HAMD评分均显著低于对照组同期(P<0.05)。2组治疗3、6周5-HT、BDN水平均显著高于本组治疗前(P<0.05),治疗6周5-HT、BDNF水平均显著高于本组治疗3周(P<0.05);治疗3、6周治疗组5-HT和BDNF水平显著高于对照组同期(P<0.05)。结论柴胡加龙骨牡蛎汤联合艾司西酞普兰能改善PSD抑郁状态、神经功能及血清BDNF、5-HT水平。 展开更多
关键词 卒中 抑郁 中西医结合疗法
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中药联合聚焦超声消融手术治疗子宫肌瘤临床观察
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作者 张代碧 吴敏 +7 位作者 雷婷婷 李晓辉 何玉春 冉峰 代艳 周义杰 张亚楠 王幸栓 《山西中医》 2024年第1期15-18,共4页
目的:观察中药联合聚焦超声消融手术治疗子宫肌瘤的近期和远期疗效,以及对生殖激素的影响。方法:选取拟行聚焦超声消融手术(FUAS)的子宫肌瘤患者86例为研究对象,治疗组45例予FUAS联合中药治疗,对照组41例单纯予FUAS。另选行全子宫切除... 目的:观察中药联合聚焦超声消融手术治疗子宫肌瘤的近期和远期疗效,以及对生殖激素的影响。方法:选取拟行聚焦超声消融手术(FUAS)的子宫肌瘤患者86例为研究对象,治疗组45例予FUAS联合中药治疗,对照组41例单纯予FUAS。另选行全子宫切除术的子宫肌瘤患者29例为切除术组。比较对照组与切除术组治疗前后生殖激素变化,比较治疗组与对照组子宫肌瘤体积变化、PBAC评分。结果:术后对照组FSH、LH、E2水平与术前比较无统计学差异(P>0.05),切除术组FSH、LH水平较术前有所升高(P<0.05)。术后治疗组与对照组子宫肌瘤总体积较术前均明显缩小,治疗组较对照组肌瘤缩小更显著;两组月经PBAC评分较术前均有明显降低(P<0.05)。结论:聚焦超声消融手术治疗子宫肌瘤能有效缩小肌瘤体积,对患者卵巢内分泌功能无明显影响。中药联合FUAS能够更有效缩小肌瘤体积,改善月经量和临床症状。 展开更多
关键词 子宫肌瘤 聚焦超声消融术 中西医结合疗法
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Analysis of Clinical Evaluation of Response to Treatment of Parkinson's Disease with Integrated Chinese and Western Medicine Therapy 被引量:7
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作者 李敏 杨明会 +3 位作者 刘毅 雒晓东 陈建宗 史恒军 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2015年第1期17-21,共5页
Objective: To analyze the clinical evaluation of Parkinson's disease (PD) patients receiving integrated Chinese and Western medicine therapy. Methods: One hundred and twenty patients were enrolled and randomly al... Objective: To analyze the clinical evaluation of Parkinson's disease (PD) patients receiving integrated Chinese and Western medicine therapy. Methods: One hundred and twenty patients were enrolled and randomly allocated to a control group or treatment group. Patients in the two groups received placebo and Bushen Huoxue Granule (补肾活血颗粒, BHG), respectively. Both groups received baseline levodopa and benserazide (Madopar). The effects of treatment were assessed monthly during the 9-month treatment. Means of evaluation included Unified PD Rating Scale (UPDRS) scores (Ⅱ and Ⅲ), sleep scale score, 10 m turn back test (getting up time, 10 m × 2 times, and turning time), timing motor test (TMT)-Ieft and TMT-right, which were treated as the dependent variables; and age, sex, duration of PD, Hoehn and Yahr (H-Y) stage and Madopar dosage of admitted PD patients were as the independent variables. Multiple linear regression was used to analyze these factors. Results: H-Y stage significantly affected UPDRSⅡ score, UPDRS Ⅲ score, and getting up time (P〈0.01). Madopar dosage and H-Y stage significantly affected the 10 m × 2 times (P〈0.05 or P〈0.01). Madopar dosage significantly affected the sleep scale score (P〈0.05). There were also significant correlations between age and TMT-left or TMT-right (P〈0.01), and duration of PD and TMT-right (P〈0.05). Conclusions: The six assessed means of clinical evaluation (including UPDRS Ⅱ and UPDRS Ⅲ scores, sleep scale score, getting up time, 10 m × 2 times, and turning time) are sensitive indexes in all PD patients. H-Y stage and Madopar dosage are the major factors influencing means of clinical assessment of PD treatment. 展开更多
关键词 Parkinson's disease integrated chinese and Western medicine therapy means of clinicalevaluation
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