With the rapid development of globalization and information technology,intellectual property has been one of the key drivers of economic growth,and the construction of intellectual property system has become an import...With the rapid development of globalization and information technology,intellectual property has been one of the key drivers of economic growth,and the construction of intellectual property system has become an important criterion for measuring the quality of business environment.This article is intended to explore the current status of intellectual property system construction in China,the challenges,and its relationship with the business environment,to propose the corresponding countermeasures and suggestions.The study finds that the legal system of intellectual property in China is gradually improving,and judicial and administrative protection are continuously strengthened.However,the challenges still remain such as frequent infringements,rights hard to protect and insufficient international cooperation.These issues not only affect the legitimate rights and interests of innovation entities,but also for the market fairness and the level of the business environment.Therefore,this article proposes that strengthening the perfection of the intellectual property legal system,enhancing intellectual property services and support capabilities,strengthening international cooperation and exchanges,and accelerating the cultivation of composite talents.It aims to provide theoretical references for the construction of intellectual property system and the optimization of the business environment,promote the high-quality development of economy and enhance the global competitiveness of the country.展开更多
This paper is part of a research into the Latin American thinking on international affairs and a continuation of a line of work on Latin American contributions to the environmental discussion installed in the global p...This paper is part of a research into the Latin American thinking on international affairs and a continuation of a line of work on Latin American contributions to the environmental discussion installed in the global political agenda in the early 70s. The premise was that Latin American contributions were initially made by professionals closely related to ECLAC, UNEP and the Bariloche Foundation. These professionals and agencies understood how poverty and backwardness were endured by the majority of the regional and world’s population was one of the main causes of environmental degradation;consequently, overcoming the environmental crisis meant that underdevelopment should be eradicated without delay. This view of the environmental problems was synthesized in the combined concept of “environment and development”, which was also understood in the region as “eco development”. Finally, the broad phenomenon they wanted to describe using the terms “environment and development” was summarized in the concept of sustainable development as defined in the 1987 World Commission on Environment and Development report “Our Common Future”.展开更多
Nam Cao and Lu Xun are among high-profile writers who gain wide appreciation. The movements of literary assert this over the latter half of recent century in our country. That reality persistently points us to an urge...Nam Cao and Lu Xun are among high-profile writers who gain wide appreciation. The movements of literary assert this over the latter half of recent century in our country. That reality persistently points us to an urgent need for researches on Nam Cao and Lu Xun. Tints of literary worldviews of Nam Cao and Lu Xun, though upon which numberless research works, both domestic and foreign, have provided multi-directional insights and exploration of artistic creativities, remain misevaluated. B ich Thu, the author of Nam Cao, His Life and Legacies, counted out 191 articles and books themed Nam Cao. They were edited by writers of Nam Cao's generation namely Nguyen Huy Tuong, Nguyen Dinh Thi, To Hoai and Nguyen Hong, and even distinguished scholars such as Ha Minh Duc, Phong Le and Nguyen Dang Manh, so on. Regarding Lu Xun, there is no denying the fact of his brilliant artistic ideology. Although Vietnamese readers have gained a late knowledge of him for just a half of century, his name is laid somewhere in the heart of our people, integrally and consistently. Vietnam's reader generations restlessly learn about and research on Lu Xun. A pioneering merit badge should be rewarded to the renowned literary critic Dang Thai Mai, for his introduction and translation of Lu Xun to Vietnamese readers since 1943. The most interesting coincidence of Nam Cao and Lu Xun is that their profiles are imbued with the characters in their compositions. Mentioning Lu Xun cannot help a reference to AQ, meanwhile the name ofNam Cao apparently recalls a Philistine Chi. AQ as well as Philistine Chi have become characters of the society's spiritual life and long live with the eternal brilliance of their two creators. That coincidence draws countless number of researchers. The "matching point", referring to the subject of farmers and intellectuals, between Nam Cao and Lu Xun's works has been explored to some certain extent. This elicitly invites us for deeper studies. The author of this article, in response to such invitation, delves into the subject with respect to characterization of intellectuals in Nam Cao and Lu Xun's short stories.展开更多
Introduction: Music therapy is a practice for helping and supporting people with intellectual and relational difficulties. This study illustrated the benefits of music therapy for young people living with intellectual...Introduction: Music therapy is a practice for helping and supporting people with intellectual and relational difficulties. This study illustrated the benefits of music therapy for young people living with intellectual disabilities (YLID) in an African context. Methodology: This study investigated six young individuals with intellectual disabilities who had undergone three years of music therapy. They were participants in the inclusive non-academic training program at the National School of Arts in Dakar from 2017 to 2019. Data collection utilized individual interviews with the youths, evaluation grids from teachers and psychiatrists. Guardians provided informed consent along with the assent of the young participants. Results: The six young were aged between 18 and 30 years old, with an average age of 24.6 years. Four of the YLID were male. Three young people with intellectual disabilities had delayed psychomotor development. Observations revealed the beneficial influence of music therapy on the health and well-being of young individuals. Music played a role in alleviating stress and anxiety among youth with intellectual disabilities (YLID), enhancing their mood and mental health. It assisted in navigating challenging situations and heightened alertness among YLID. Additionally, music therapy contributed to improvements in dyslexia, fine and gross motor skills, and memory development among intellectually disabled youth, ultimately facilitating their integration into society. Conclusion: In light of our results, music therapy makes a major contribution to the empowerment of YLID. Engaging in musical activities helps young people connect with others through instrumental expression and a sense of accomplishment. By facilitating music therapy, it becomes possible to combat discrimination and stigmatization, thus promoting the social inclusion of intellectually disabled youth. Therefore, it is important to promote music therapy in Senegal to meet the needs of YLID.展开更多
Introduction: Several studies have reported a high prevalence of dental caries among the people with intellectual disabilities. In order to identify the sociodemographic, clinical and behavioral factors associated wit...Introduction: Several studies have reported a high prevalence of dental caries among the people with intellectual disabilities. In order to identify the sociodemographic, clinical and behavioral factors associated with it, we conducted a study in specialized centers welcoming subjects with intellectual disabilities in Ouagadougou (Burkina Faso). Objectives: The objective of this study was to identify the factors associated with it among intellectually disabled in the specialized centers of Ouagadougou. Methods: The study was cross-sectional analytical. The survey took place between November 2020 and January 2021 among people with intellectual disabilities in reception centers receiving a grant from the Ministry of Women, National Solidarity, Family and Humanitarian Action. Data collection was done with a questionnaire adapted from the World Health Organization (WHO) and dental caries was recorded according to WHO criteria in decayed, missing or filled teeth generating a DMF index. Logistic regression was used to identify factors associated with the presence of dental caries. Results: A total of 193 participants were included in the study with an average age of 12.4 years ± 7.9. The overall prevalence of caries measured with the DMF index was 58.6% 95% CI [51.2 - 65.8]. It was significantly associated with female gender (OR = 4.2;95% CI [1.4 - 12.5], p = 0,01), the clinical form of mental illness (epilepsy OR = 3.8 95%;CI [1.2 - 12.7], p = 0,02, trisomy OR = 5.0;95% CI [1.1 - 22.9], p = 0,03, motor autonomy OR = 0.2 95%;CI [0.1 - 0.7], p = 0,01) and at use of toothpaste OR = 9.33;95% CI [1.05 - 82.7], p = 0,04. Conclusion: Dental caries remains a very present pathology in most people living with an intellectual disability. Also, it is necessary to put in place prevention strategies to reduce its prevalence and improve access to oral care for these people.展开更多
Background: There is limited knowledge about obsessive-compulsive disorder (OCD) in people with intellectual disabilities (IDs). This paper describes the manifestation of compulsive behaviors associated with OCD at th...Background: There is limited knowledge about obsessive-compulsive disorder (OCD) in people with intellectual disabilities (IDs). This paper describes the manifestation of compulsive behaviors associated with OCD at the behavioral level in people with ID in institutionalized settings. The aim was to gain nuanced insight into appropriate understanding and classification in this specific context, and derive implications for research and practice. Methods: Individual cases of people with ID (n = 7) were studied to assess compulsive symptoms through two days of on-site observation of the person with ID within the institution, guided group discussions (n = 28), and semi-structured interviews with key informants and caregivers of the person with ID (n = 20). Caregiver ratings of the compulsive behavior checklist were compiled. Data were analyzed using qualitative content analysis. Results: All forms of OCD were present. Characteristics of compulsive behaviors in people with ID at the behavioral level included less complex and more obvious compulsive acts, immediate responses, signs of tension, motor restlessness, facial expression changes, repetition, need for predictability, time-consuming behaviors, and aggressive reactions when these acts were interrupted. Some of the compulsive behaviors corresponded to the ICD-11 OCD code 6B20, and others to compulsions as a psychological symptom (MB23.4). Conclusions: OCD may manifest atypically at the behavioral level in people with ID, posing significant challenges for accurate classification due to symptom ambiguity. Follow-up differential diagnostic studies are needed to more accurately identify and differentiate OCD symptoms in people with ID. Further, disorder-specific guidelines for recognizing OCD in people with ID are needed for institutionalized settings without psychiatric-psychotherapeutic expertise.展开更多
The main obstacle to the open sharing of scientific data is the lack of a legal protection system for intellectual property.This article analyzes the progress of research papers on intellectual property in scientific ...The main obstacle to the open sharing of scientific data is the lack of a legal protection system for intellectual property.This article analyzes the progress of research papers on intellectual property in scientific data in China through literature search and statistics.Currently,research subjects are unbalanced,research content is uneven,research methods are intellectual single,and research depth is insufficient.It is recommended that different stakeholders engage in deep cross disciplinary cooperation,further improve China’s legal and policy protection system for scientific data intellectual property,and promote the open sharing of scientific data.展开更多
Accelerating the construction of agricultural power,further promoting the high-quality development of the Yangtze River Economic Belt,and better supporting and serving Chinese-style modernization are the key issues at...Accelerating the construction of agricultural power,further promoting the high-quality development of the Yangtze River Economic Belt,and better supporting and serving Chinese-style modernization are the key issues at present.This paper first introduces the Yangtze River Economic Belt and its ethnic areas,and studies the characteristics of the grain and oil industry in the ethnic autonomous areas of the economic belt,as well as the current situation of various types of intellectual property resources,such as industrial cultural heritage,scientific and tech-nological innovation,and brand marking intellectual property.Besides,it analyzes the main problems in the high-quality development of grain and oil in the Yangtze River Economic Belt ethnic areas.Finally,it comes up with recommendations,including protecting the intellectual prop-erty rights of cultural heritage in the field of grain and oil,leading the inheritance and development of excellent traditional Chinese culture,use scientific and technological innovation intellectual property rights to promote the innovation-driven development strategy of the grain and oil in-dustry,and providing counterpart assistance to ethnic autonomous areas in the Yangtze River Economic Belt to further promote the high-quality development of the Yangtze River Economic Belt.展开更多
Logging data and its interpretation results are one of the most important basic data for understanding reservoirs and oilfield development. Standardized and unified logging interpretation results play a decisive role ...Logging data and its interpretation results are one of the most important basic data for understanding reservoirs and oilfield development. Standardized and unified logging interpretation results play a decisive role in fine reservoir description and reservoir development. Aiming at the problem of the conflict between the development effect and the initial interpretation result of Yan 9 reservoir in Hujianshan area of Ordos Basin, by combining the current well production performance, logging, oil test, production test and other data, on the basis of making full use of core, coring, logging, thin section analysis and high pressure mercury injection data, the four characteristics of reservoir are analyzed, a more scientific and reasonable calculation model of reservoir logging parameters is established, and the reserves are recalculated after the second interpretation standard of logging is determined. The research improves the accuracy of logging interpretation and provides an effective basis for subsequent production development and potential horizons.展开更多
Nanyang pyrography is a special art from Nanyang that is important in the art world.It has a unique way of showing things with good skills.This art shows the deep culture and beauty of Nanyang and is a famous symbol o...Nanyang pyrography is a special art from Nanyang that is important in the art world.It has a unique way of showing things with good skills.This art shows the deep culture and beauty of Nanyang and is a famous symbol of its culture.展开更多
Nanyang,a city with a long history,offers many kinds of delicious food.Xinye board noodles stand out as a remarkable(显著的)one.With unique taste and local features,they have become a significant(重要的)symbol of Nany...Nanyang,a city with a long history,offers many kinds of delicious food.Xinye board noodles stand out as a remarkable(显著的)one.With unique taste and local features,they have become a significant(重要的)symbol of Nanyang cuisine.展开更多
Steelmaking plant of Fujian San Gang min Guang Co.,Ltd.is keeping pace with the trend of the times.Under the new situation that the labor cost is rising day by day.Constantly introducing intelligent technology to impr...Steelmaking plant of Fujian San Gang min Guang Co.,Ltd.is keeping pace with the trend of the times.Under the new situation that the labor cost is rising day by day.Constantly introducing intelligent technology to improve the level of automation operation and reducing labor intensity of staff and workers.Especially under the support of MES information system.Advanced and practical technology is adopted in converter,refining and continuous casting process.In recent years,production management and control,energy management and control,material tracking,cost control and equipment operation and maintenance and reducing personnel to new achieve-ments in reducing personnel.展开更多
Yan 220S, which is derived from a natural variant plant discovered among the population of Guangzhan 63S and developed by Jiangsu Agricultural Research Institute for Coastal Regions through pedigree selection over yea...Yan 220S, which is derived from a natural variant plant discovered among the population of Guangzhan 63S and developed by Jiangsu Agricultural Research Institute for Coastal Regions through pedigree selection over years, is an indica photo- and thermo-sensitive genic male sterile (PTGMS) line in rice. In 2013, it was technically identified by Jiangsu Crop Variety Appraisal Committee. Its hybrid Yan-liangyou 2208 (Yan 220S/Yanhui 888), a new two-line hybrid rice combination with high yield and good grain quality, was subsequently developed and released for commercial production by the National Crop Variety Appraisal Committee in 2013.展开更多
In 2006, the indica photoperiod- and thermo-sensitive genic male sterile (PTGMS) line Yan 161S was successful y bred by crossing the Guangzhan 63S (♀) and the medium indica breeding material Yan 229 (♂), which...In 2006, the indica photoperiod- and thermo-sensitive genic male sterile (PTGMS) line Yan 161S was successful y bred by crossing the Guangzhan 63S (♀) and the medium indica breeding material Yan 229 (♂), which was bred by the Institute of Agricultural Sciences in Coastal Region of Jiangsu Province, after years' and generations’ selection in different areas. It passed the identification by Jiangsu Provincial Crop Variety Appraisal Committee in 2013. Crossing the Yan 161S with Yanhui 888, a new high-yielding and high-quality two-line hybrid rice combination Yanliangyou 1618 was developed, and it passed the variety identification in 2014. This paper introduced the breeding processes and characteristics of Yan 161S and Yanliangyou 1618 and the cultivation and seed production techniques of Yanliangyou 1618.展开更多
The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKS...The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully understood.Research has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic spines.However,the function of CNKSR2 in the cytoplasm remains to be elucidated.In this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of CNKSR2.Through a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the centrosome.We also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker CEP290.Subsequent colocalization analysis confirmed the centrosomal localization of CNKSR2.When we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal genes.This manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and motility.Furthermore,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum disorder.Our findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.展开更多
基金Guizhou Provincial University Humanities and Social Sciences Research Project in 2024"Enhancing the Development of New Productive Forces through University Technological Innovation and Intellectual Property Management"(2024RW256)Guizhou University of Commerce Research Project in 2022"Study on the Ideas and Pathways to Drive Agricultural Powerhouse through Digital Economy"(2022XJZX315)。
文摘With the rapid development of globalization and information technology,intellectual property has been one of the key drivers of economic growth,and the construction of intellectual property system has become an important criterion for measuring the quality of business environment.This article is intended to explore the current status of intellectual property system construction in China,the challenges,and its relationship with the business environment,to propose the corresponding countermeasures and suggestions.The study finds that the legal system of intellectual property in China is gradually improving,and judicial and administrative protection are continuously strengthened.However,the challenges still remain such as frequent infringements,rights hard to protect and insufficient international cooperation.These issues not only affect the legitimate rights and interests of innovation entities,but also for the market fairness and the level of the business environment.Therefore,this article proposes that strengthening the perfection of the intellectual property legal system,enhancing intellectual property services and support capabilities,strengthening international cooperation and exchanges,and accelerating the cultivation of composite talents.It aims to provide theoretical references for the construction of intellectual property system and the optimization of the business environment,promote the high-quality development of economy and enhance the global competitiveness of the country.
文摘This paper is part of a research into the Latin American thinking on international affairs and a continuation of a line of work on Latin American contributions to the environmental discussion installed in the global political agenda in the early 70s. The premise was that Latin American contributions were initially made by professionals closely related to ECLAC, UNEP and the Bariloche Foundation. These professionals and agencies understood how poverty and backwardness were endured by the majority of the regional and world’s population was one of the main causes of environmental degradation;consequently, overcoming the environmental crisis meant that underdevelopment should be eradicated without delay. This view of the environmental problems was synthesized in the combined concept of “environment and development”, which was also understood in the region as “eco development”. Finally, the broad phenomenon they wanted to describe using the terms “environment and development” was summarized in the concept of sustainable development as defined in the 1987 World Commission on Environment and Development report “Our Common Future”.
文摘Nam Cao and Lu Xun are among high-profile writers who gain wide appreciation. The movements of literary assert this over the latter half of recent century in our country. That reality persistently points us to an urgent need for researches on Nam Cao and Lu Xun. Tints of literary worldviews of Nam Cao and Lu Xun, though upon which numberless research works, both domestic and foreign, have provided multi-directional insights and exploration of artistic creativities, remain misevaluated. B ich Thu, the author of Nam Cao, His Life and Legacies, counted out 191 articles and books themed Nam Cao. They were edited by writers of Nam Cao's generation namely Nguyen Huy Tuong, Nguyen Dinh Thi, To Hoai and Nguyen Hong, and even distinguished scholars such as Ha Minh Duc, Phong Le and Nguyen Dang Manh, so on. Regarding Lu Xun, there is no denying the fact of his brilliant artistic ideology. Although Vietnamese readers have gained a late knowledge of him for just a half of century, his name is laid somewhere in the heart of our people, integrally and consistently. Vietnam's reader generations restlessly learn about and research on Lu Xun. A pioneering merit badge should be rewarded to the renowned literary critic Dang Thai Mai, for his introduction and translation of Lu Xun to Vietnamese readers since 1943. The most interesting coincidence of Nam Cao and Lu Xun is that their profiles are imbued with the characters in their compositions. Mentioning Lu Xun cannot help a reference to AQ, meanwhile the name ofNam Cao apparently recalls a Philistine Chi. AQ as well as Philistine Chi have become characters of the society's spiritual life and long live with the eternal brilliance of their two creators. That coincidence draws countless number of researchers. The "matching point", referring to the subject of farmers and intellectuals, between Nam Cao and Lu Xun's works has been explored to some certain extent. This elicitly invites us for deeper studies. The author of this article, in response to such invitation, delves into the subject with respect to characterization of intellectuals in Nam Cao and Lu Xun's short stories.
文摘Introduction: Music therapy is a practice for helping and supporting people with intellectual and relational difficulties. This study illustrated the benefits of music therapy for young people living with intellectual disabilities (YLID) in an African context. Methodology: This study investigated six young individuals with intellectual disabilities who had undergone three years of music therapy. They were participants in the inclusive non-academic training program at the National School of Arts in Dakar from 2017 to 2019. Data collection utilized individual interviews with the youths, evaluation grids from teachers and psychiatrists. Guardians provided informed consent along with the assent of the young participants. Results: The six young were aged between 18 and 30 years old, with an average age of 24.6 years. Four of the YLID were male. Three young people with intellectual disabilities had delayed psychomotor development. Observations revealed the beneficial influence of music therapy on the health and well-being of young individuals. Music played a role in alleviating stress and anxiety among youth with intellectual disabilities (YLID), enhancing their mood and mental health. It assisted in navigating challenging situations and heightened alertness among YLID. Additionally, music therapy contributed to improvements in dyslexia, fine and gross motor skills, and memory development among intellectually disabled youth, ultimately facilitating their integration into society. Conclusion: In light of our results, music therapy makes a major contribution to the empowerment of YLID. Engaging in musical activities helps young people connect with others through instrumental expression and a sense of accomplishment. By facilitating music therapy, it becomes possible to combat discrimination and stigmatization, thus promoting the social inclusion of intellectually disabled youth. Therefore, it is important to promote music therapy in Senegal to meet the needs of YLID.
文摘Introduction: Several studies have reported a high prevalence of dental caries among the people with intellectual disabilities. In order to identify the sociodemographic, clinical and behavioral factors associated with it, we conducted a study in specialized centers welcoming subjects with intellectual disabilities in Ouagadougou (Burkina Faso). Objectives: The objective of this study was to identify the factors associated with it among intellectually disabled in the specialized centers of Ouagadougou. Methods: The study was cross-sectional analytical. The survey took place between November 2020 and January 2021 among people with intellectual disabilities in reception centers receiving a grant from the Ministry of Women, National Solidarity, Family and Humanitarian Action. Data collection was done with a questionnaire adapted from the World Health Organization (WHO) and dental caries was recorded according to WHO criteria in decayed, missing or filled teeth generating a DMF index. Logistic regression was used to identify factors associated with the presence of dental caries. Results: A total of 193 participants were included in the study with an average age of 12.4 years ± 7.9. The overall prevalence of caries measured with the DMF index was 58.6% 95% CI [51.2 - 65.8]. It was significantly associated with female gender (OR = 4.2;95% CI [1.4 - 12.5], p = 0,01), the clinical form of mental illness (epilepsy OR = 3.8 95%;CI [1.2 - 12.7], p = 0,02, trisomy OR = 5.0;95% CI [1.1 - 22.9], p = 0,03, motor autonomy OR = 0.2 95%;CI [0.1 - 0.7], p = 0,01) and at use of toothpaste OR = 9.33;95% CI [1.05 - 82.7], p = 0,04. Conclusion: Dental caries remains a very present pathology in most people living with an intellectual disability. Also, it is necessary to put in place prevention strategies to reduce its prevalence and improve access to oral care for these people.
文摘Background: There is limited knowledge about obsessive-compulsive disorder (OCD) in people with intellectual disabilities (IDs). This paper describes the manifestation of compulsive behaviors associated with OCD at the behavioral level in people with ID in institutionalized settings. The aim was to gain nuanced insight into appropriate understanding and classification in this specific context, and derive implications for research and practice. Methods: Individual cases of people with ID (n = 7) were studied to assess compulsive symptoms through two days of on-site observation of the person with ID within the institution, guided group discussions (n = 28), and semi-structured interviews with key informants and caregivers of the person with ID (n = 20). Caregiver ratings of the compulsive behavior checklist were compiled. Data were analyzed using qualitative content analysis. Results: All forms of OCD were present. Characteristics of compulsive behaviors in people with ID at the behavioral level included less complex and more obvious compulsive acts, immediate responses, signs of tension, motor restlessness, facial expression changes, repetition, need for predictability, time-consuming behaviors, and aggressive reactions when these acts were interrupted. Some of the compulsive behaviors corresponded to the ICD-11 OCD code 6B20, and others to compulsions as a psychological symptom (MB23.4). Conclusions: OCD may manifest atypically at the behavioral level in people with ID, posing significant challenges for accurate classification due to symptom ambiguity. Follow-up differential diagnostic studies are needed to more accurately identify and differentiate OCD symptoms in people with ID. Further, disorder-specific guidelines for recognizing OCD in people with ID are needed for institutionalized settings without psychiatric-psychotherapeutic expertise.
文摘The main obstacle to the open sharing of scientific data is the lack of a legal protection system for intellectual property.This article analyzes the progress of research papers on intellectual property in scientific data in China through literature search and statistics.Currently,research subjects are unbalanced,research content is uneven,research methods are intellectual single,and research depth is insufficient.It is recommended that different stakeholders engage in deep cross disciplinary cooperation,further improve China’s legal and policy protection system for scientific data intellectual property,and promote the open sharing of scientific data.
基金Supported by Special Soft Science Research Project for Hubei Province Science and Technology Innovation Talents and Services(2022EDA060).
文摘Accelerating the construction of agricultural power,further promoting the high-quality development of the Yangtze River Economic Belt,and better supporting and serving Chinese-style modernization are the key issues at present.This paper first introduces the Yangtze River Economic Belt and its ethnic areas,and studies the characteristics of the grain and oil industry in the ethnic autonomous areas of the economic belt,as well as the current situation of various types of intellectual property resources,such as industrial cultural heritage,scientific and tech-nological innovation,and brand marking intellectual property.Besides,it analyzes the main problems in the high-quality development of grain and oil in the Yangtze River Economic Belt ethnic areas.Finally,it comes up with recommendations,including protecting the intellectual prop-erty rights of cultural heritage in the field of grain and oil,leading the inheritance and development of excellent traditional Chinese culture,use scientific and technological innovation intellectual property rights to promote the innovation-driven development strategy of the grain and oil in-dustry,and providing counterpart assistance to ethnic autonomous areas in the Yangtze River Economic Belt to further promote the high-quality development of the Yangtze River Economic Belt.
文摘Logging data and its interpretation results are one of the most important basic data for understanding reservoirs and oilfield development. Standardized and unified logging interpretation results play a decisive role in fine reservoir description and reservoir development. Aiming at the problem of the conflict between the development effect and the initial interpretation result of Yan 9 reservoir in Hujianshan area of Ordos Basin, by combining the current well production performance, logging, oil test, production test and other data, on the basis of making full use of core, coring, logging, thin section analysis and high pressure mercury injection data, the four characteristics of reservoir are analyzed, a more scientific and reasonable calculation model of reservoir logging parameters is established, and the reserves are recalculated after the second interpretation standard of logging is determined. The research improves the accuracy of logging interpretation and provides an effective basis for subsequent production development and potential horizons.
文摘Nanyang pyrography is a special art from Nanyang that is important in the art world.It has a unique way of showing things with good skills.This art shows the deep culture and beauty of Nanyang and is a famous symbol of its culture.
文摘Nanyang,a city with a long history,offers many kinds of delicious food.Xinye board noodles stand out as a remarkable(显著的)one.With unique taste and local features,they have become a significant(重要的)symbol of Nanyang cuisine.
文摘Steelmaking plant of Fujian San Gang min Guang Co.,Ltd.is keeping pace with the trend of the times.Under the new situation that the labor cost is rising day by day.Constantly introducing intelligent technology to improve the level of automation operation and reducing labor intensity of staff and workers.Especially under the support of MES information system.Advanced and practical technology is adopted in converter,refining and continuous casting process.In recent years,production management and control,energy management and control,material tracking,cost control and equipment operation and maintenance and reducing personnel to new achieve-ments in reducing personnel.
基金Supported by National Key Technology R&D Program(2015BAD01B02)Strategic Forerunner Scientific Special Project of Chinese Academy of Sciences(XDA08030104)+1 种基金Special Project for"Breeding of Seven Major Crops"of National Key Research and Development Plan(2017YFD0100300)Independent Innovation Foundation for Agricultural Science and Technology in Jiangsu Province[CX(15)1005]~~
文摘Yan 220S, which is derived from a natural variant plant discovered among the population of Guangzhan 63S and developed by Jiangsu Agricultural Research Institute for Coastal Regions through pedigree selection over years, is an indica photo- and thermo-sensitive genic male sterile (PTGMS) line in rice. In 2013, it was technically identified by Jiangsu Crop Variety Appraisal Committee. Its hybrid Yan-liangyou 2208 (Yan 220S/Yanhui 888), a new two-line hybrid rice combination with high yield and good grain quality, was subsequently developed and released for commercial production by the National Crop Variety Appraisal Committee in 2013.
基金Supported by Jiangsu Agricultural Science and Technology Innovation Fund[CX(14)2047]"333 Project"of Jiangsu Province(BRA2012084)~~
文摘In 2006, the indica photoperiod- and thermo-sensitive genic male sterile (PTGMS) line Yan 161S was successful y bred by crossing the Guangzhan 63S (♀) and the medium indica breeding material Yan 229 (♂), which was bred by the Institute of Agricultural Sciences in Coastal Region of Jiangsu Province, after years' and generations’ selection in different areas. It passed the identification by Jiangsu Provincial Crop Variety Appraisal Committee in 2013. Crossing the Yan 161S with Yanhui 888, a new high-yielding and high-quality two-line hybrid rice combination Yanliangyou 1618 was developed, and it passed the variety identification in 2014. This paper introduced the breeding processes and characteristics of Yan 161S and Yanliangyou 1618 and the cultivation and seed production techniques of Yanliangyou 1618.
基金supported by the National Nature Science Foundation of China,No.32101020(to JL)the Natural Science Foundation of Shandong Province,Nos.ZR2020MC071(to JL),ZR2023MH327(to HZ)+1 种基金the Integrated Project of Major Research Plan of National Natural Science Foundation of China,No.92249303(to PL)the Natural Science Foundation of Qingdao,No.23-2-1-193-zyyd-jch(to HZ)。
文摘The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully understood.Research has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic spines.However,the function of CNKSR2 in the cytoplasm remains to be elucidated.In this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of CNKSR2.Through a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the centrosome.We also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker CEP290.Subsequent colocalization analysis confirmed the centrosomal localization of CNKSR2.When we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal genes.This manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and motility.Furthermore,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum disorder.Our findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.