A novel notion of self-organization whose major property is that it brings about the execution of semantic intelligence as spontaneous physico-chemical processes in an unspecified ever-changing non-uniform environment...A novel notion of self-organization whose major property is that it brings about the execution of semantic intelligence as spontaneous physico-chemical processes in an unspecified ever-changing non-uniform environment is introduced. Its greatest advantage is that the covariance of causality encapsulated in any piece of semantic intelligence is provided with a great diversity of its individuality viewed as the properties of the current response and its reproducibility viewed as causality encapsulated in any of the homeostatic patterns. Alongside, the consistency of the functional metrics, which is always Euclidean, with any metrics of the space-time renders the proposed notion of self-organization ubiquitously available.展开更多
As a powerful paradigm,artificial intelligence(AI)is rapidly impacting every aspect of our day-to-day life and scientific research through interdisciplinary transformations.Living human organoids(LOs)have a great pote...As a powerful paradigm,artificial intelligence(AI)is rapidly impacting every aspect of our day-to-day life and scientific research through interdisciplinary transformations.Living human organoids(LOs)have a great potential for in vitro reshaping many aspects of in vivo true human organs,including organ development,disease occurrence,and drug responses.To date,AI has driven the revolutionary advances of human organoids in life science,precision medicine and pharmaceutical science in an unprecedented way.Herein,we provide a forward-looking review,the frontiers of LOs,covering the engineered construction strategies and multidisciplinary technologies for developing LOs,highlighting the cutting-edge achievements and the prospective applications of AI in LOs,particularly in biological study,disease occurrence,disease diagnosis and prediction and drug screening in preclinical assay.Moreover,we shed light on the new research trends harnessing the power of AI for LO research in the context of multidisciplinary technologies.The aim of this paper is to motivate researchers to explore organ function throughout the human life cycle,narrow the gap between in vitro microphysiological models and the real human body,accurately predict human-related responses to external stimuli(cues and drugs),accelerate the preclinical-to-clinical transformation,and ultimately enhance the health and well-being of patients.展开更多
Organic chemistry is undergoing a major paradigm shift,moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence(AI).This transformative shift is being driven by technolog...Organic chemistry is undergoing a major paradigm shift,moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence(AI).This transformative shift is being driven by technological advances,the ever-increasing demand for greater research efficiency and accuracy,and the burgeoning growth of interdisciplinary research.AI models,supported by computational power and algorithms,are drastically reshaping synthetic planning and introducing groundbreaking ways to tackle complex molecular synthesis.In addition,autonomous robotic systems are rapidly accelerating the pace of discovery by performing tedious tasks with unprecedented speed and precision.This article examines the multiple opportunities and challenges presented by this paradigm shift and explores its far-reaching implications.It provides valuable insights into the future trajectory of organic chemistry research,which is increasingly defined by the synergistic interaction of automation and AI.展开更多
BACKGROUND Machine learning(ML),a major branch of artificial intelligence,has not only demonstrated the potential to significantly improve numerous sectors of healthcare but has also made significant contributions to ...BACKGROUND Machine learning(ML),a major branch of artificial intelligence,has not only demonstrated the potential to significantly improve numerous sectors of healthcare but has also made significant contributions to the field of solid organ transplantation.ML provides revolutionary opportunities in areas such as donorrecipient matching,post-transplant monitoring,and patient care by automatically analyzing large amounts of data,identifying patterns,and forecasting outcomes.AIM To conduct a comprehensive bibliometric analysis of publications on the use of ML in transplantation to understand current research trends and their implications.METHODS On July 18,a thorough search strategy was used with the Web of Science database.ML and transplantation-related keywords were utilized.With the aid of the VOS viewer application,the identified articles were subjected to bibliometric variable analysis in order to determine publication counts,citation counts,contributing countries,and institutions,among other factors.RESULTS Of the 529 articles that were first identified,427 were deemed relevant for bibliometric analysis.A surge in publications was observed over the last four years,especially after 2018,signifying growing interest in this area.With 209 publications,the United States emerged as the top contributor.Notably,the"Journal of Heart and Lung Transplantation"and the"American Journal of Transplantation"emerged as the leading journals,publishing the highest number of relevant articles.Frequent keyword searches revealed that patient survival,mortality,outcomes,allocation,and risk assessment were significant themes of focus.CONCLUSION The growing body of pertinent publications highlights ML's growing presence in the field of solid organ transplantation.This bibliometric analysis highlights the growing importance of ML in transplant research and highlights its exciting potential to change medical practices and enhance patient outcomes.Encouraging collaboration between significant contributors can potentially fast-track advancements in this interdisciplinary domain.展开更多
Organization intelligence is an important index for evaluating competition ability of organization. This paper applies the Entropy concept to evaluate the level of organization intelligence and set up the framework of...Organization intelligence is an important index for evaluating competition ability of organization. This paper applies the Entropy concept to evaluate the level of organization intelligence and set up the framework of entropy evaluation theory related to the environment, inter-structure and behavior fields.展开更多
Converting thermal energy into mechanical work by means of Organic Rankine Cycle is a validated technology to exploit low-grade waste heat.The typical design process of Organic Rankine Cycle system,which commonly in-v...Converting thermal energy into mechanical work by means of Organic Rankine Cycle is a validated technology to exploit low-grade waste heat.The typical design process of Organic Rankine Cycle system,which commonly in-volves working fluid selection,cycle configuration selection,operating parameters optimization,and component selection and sizing,is time-consuming and highly dependent on engineer’s experience.Thus,it is difficult to achieve the optimal design in most cases.In recent decades,artificial intelligence has been gradually introduced into the design of energy system to overcome above shortcomings.In order to clarify the research field of arti-ficial intelligence technique in Organic Rankine Cycle design and guide artificial intelligence technique to assist Organic Rankine Cycle design better,this study presents a preliminary literature summary on recent progresses of artificial intelligence technique in organic Rankine cycle systems design.First,this study analyzes four main procedures which constitute a typical design process of Organic Rankine Cycle systems and finds that design problems encountered during design process can be divided into three categories:decision making,parameter optimization and parameter prediction.In the second section,a detailed literature review on each design proce-dures using artificial intelligence algorithms is presented.At last,the state of art in this field and the prospects for the future work are provided.展开更多
A simple but illustrative survey is given on various approaches of computational intelligence with their features, applications and the mathematical tools involved, among which the simulated annealing, neural networks...A simple but illustrative survey is given on various approaches of computational intelligence with their features, applications and the mathematical tools involved, among which the simulated annealing, neural networks, genetic and evolutionary programming, self-organizing learning and adapting algorithms, hidden Markov models are recommended intensively. The common mathematical features of various computational intelligence algorithms are exploited.Finally, two common principles of concessive strategies implicated in many computational intelligence algorithms are discussed.展开更多
Information networks are becoming more and more complex to accommodate a continuously increasing amount of traffic and networked devices,as well as having to cope with a growing diversity of operating environments and...Information networks are becoming more and more complex to accommodate a continuously increasing amount of traffic and networked devices,as well as having to cope with a growing diversity of operating environments and applications. Therefore,it is foreseeable that future information networks will frequently face unexpected problems,some of which could lead to the complete collapse of a network. To tackle this problem,recent attempts have been made to design novel network architectures which achieve a high level of scalability,adaptability,and robustness by taking inspiration from self-organizing biological systems. The objective of this paper is to discuss biologically inspired networking technologies.展开更多
Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest d...Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest developments in critical care,highlighting key areas of innovation.Recent advancements in critical care include Precision Medicine:Tailoring treatments based on individual patient characteristics,genomics,and biomarkers to enhance the effectiveness of therapies.The objective is to describe the recent advancements in Critical Care Medicine.Telemedicine:The integration of telehealth technologies for remote patient monitoring and consultation,facilitating timely interventions.Artificial intelligence(AI):AI-driven tools for early disease detection,predictive analytics,and treatment optimization,enhancing clinical decision-making.Organ Support:Advanced life support systems,such as Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy provide better organ support.Infection Control:Innovative infection control measures to combat emerging pathogens and reduce healthcare-associated infections.Ventilation Strategies:Precision ventilation modes and lung-protective strategies to minimize ventilatorinduced lung injury.Sepsis Management:Early recognition and aggressive management of sepsis with tailored interventions.Patient-Centered Care:A shift towards patient-centered care focusing on psychological and emotional wellbeing in addition to medical needs.We conducted a thorough literature search on PubMed,EMBASE,and Scopus using our tailored strategy,incorporating keywords such as critical care,telemedicine,and sepsis management.A total of 125 articles meeting our criteria were included for qualitative synthesis.To ensure reliability,we focused only on articles published in the English language within the last two decades,excluding animal studies,in vitro/molecular studies,and non-original data like editorials,letters,protocols,and conference abstracts.These advancements reflect a dynamic landscape in critical care medicine,where technology,research,and patient-centered approaches converge to improve the quality of care and save lives in ICUs.The future of critical care promises even more innovative solutions to meet the evolving challenges of modern medicine.展开更多
文摘A novel notion of self-organization whose major property is that it brings about the execution of semantic intelligence as spontaneous physico-chemical processes in an unspecified ever-changing non-uniform environment is introduced. Its greatest advantage is that the covariance of causality encapsulated in any piece of semantic intelligence is provided with a great diversity of its individuality viewed as the properties of the current response and its reproducibility viewed as causality encapsulated in any of the homeostatic patterns. Alongside, the consistency of the functional metrics, which is always Euclidean, with any metrics of the space-time renders the proposed notion of self-organization ubiquitously available.
基金supported by the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Projects(TSBICIP-CXRC-008)Strategic Priority Research Program of the Chinese Academy of Sciences(XDC 0110300)+2 种基金Major Project of Haihe Laboratory of Synthetic Biology(E2M9560201)National Natural Science Foundation of China(32301210&31200035)the China Postdoctoral Science Foundation(No.2022M713330).
文摘As a powerful paradigm,artificial intelligence(AI)is rapidly impacting every aspect of our day-to-day life and scientific research through interdisciplinary transformations.Living human organoids(LOs)have a great potential for in vitro reshaping many aspects of in vivo true human organs,including organ development,disease occurrence,and drug responses.To date,AI has driven the revolutionary advances of human organoids in life science,precision medicine and pharmaceutical science in an unprecedented way.Herein,we provide a forward-looking review,the frontiers of LOs,covering the engineered construction strategies and multidisciplinary technologies for developing LOs,highlighting the cutting-edge achievements and the prospective applications of AI in LOs,particularly in biological study,disease occurrence,disease diagnosis and prediction and drug screening in preclinical assay.Moreover,we shed light on the new research trends harnessing the power of AI for LO research in the context of multidisciplinary technologies.The aim of this paper is to motivate researchers to explore organ function throughout the human life cycle,narrow the gap between in vitro microphysiological models and the real human body,accurately predict human-related responses to external stimuli(cues and drugs),accelerate the preclinical-to-clinical transformation,and ultimately enhance the health and well-being of patients.
基金supported by the National Natural Science Foundation of China(22071004,21933001 and 22150013)
文摘Organic chemistry is undergoing a major paradigm shift,moving from a labor-intensive approach to a new era dominated by automation and artificial intelligence(AI).This transformative shift is being driven by technological advances,the ever-increasing demand for greater research efficiency and accuracy,and the burgeoning growth of interdisciplinary research.AI models,supported by computational power and algorithms,are drastically reshaping synthetic planning and introducing groundbreaking ways to tackle complex molecular synthesis.In addition,autonomous robotic systems are rapidly accelerating the pace of discovery by performing tedious tasks with unprecedented speed and precision.This article examines the multiple opportunities and challenges presented by this paradigm shift and explores its far-reaching implications.It provides valuable insights into the future trajectory of organic chemistry research,which is increasingly defined by the synergistic interaction of automation and AI.
文摘BACKGROUND Machine learning(ML),a major branch of artificial intelligence,has not only demonstrated the potential to significantly improve numerous sectors of healthcare but has also made significant contributions to the field of solid organ transplantation.ML provides revolutionary opportunities in areas such as donorrecipient matching,post-transplant monitoring,and patient care by automatically analyzing large amounts of data,identifying patterns,and forecasting outcomes.AIM To conduct a comprehensive bibliometric analysis of publications on the use of ML in transplantation to understand current research trends and their implications.METHODS On July 18,a thorough search strategy was used with the Web of Science database.ML and transplantation-related keywords were utilized.With the aid of the VOS viewer application,the identified articles were subjected to bibliometric variable analysis in order to determine publication counts,citation counts,contributing countries,and institutions,among other factors.RESULTS Of the 529 articles that were first identified,427 were deemed relevant for bibliometric analysis.A surge in publications was observed over the last four years,especially after 2018,signifying growing interest in this area.With 209 publications,the United States emerged as the top contributor.Notably,the"Journal of Heart and Lung Transplantation"and the"American Journal of Transplantation"emerged as the leading journals,publishing the highest number of relevant articles.Frequent keyword searches revealed that patient survival,mortality,outcomes,allocation,and risk assessment were significant themes of focus.CONCLUSION The growing body of pertinent publications highlights ML's growing presence in the field of solid organ transplantation.This bibliometric analysis highlights the growing importance of ML in transplant research and highlights its exciting potential to change medical practices and enhance patient outcomes.Encouraging collaboration between significant contributors can potentially fast-track advancements in this interdisciplinary domain.
文摘Organization intelligence is an important index for evaluating competition ability of organization. This paper applies the Entropy concept to evaluate the level of organization intelligence and set up the framework of entropy evaluation theory related to the environment, inter-structure and behavior fields.
基金The work described in this paper was supported by the National Key Research and Development Plan under Grant No.2018YFB1501004.
文摘Converting thermal energy into mechanical work by means of Organic Rankine Cycle is a validated technology to exploit low-grade waste heat.The typical design process of Organic Rankine Cycle system,which commonly in-volves working fluid selection,cycle configuration selection,operating parameters optimization,and component selection and sizing,is time-consuming and highly dependent on engineer’s experience.Thus,it is difficult to achieve the optimal design in most cases.In recent decades,artificial intelligence has been gradually introduced into the design of energy system to overcome above shortcomings.In order to clarify the research field of arti-ficial intelligence technique in Organic Rankine Cycle design and guide artificial intelligence technique to assist Organic Rankine Cycle design better,this study presents a preliminary literature summary on recent progresses of artificial intelligence technique in organic Rankine cycle systems design.First,this study analyzes four main procedures which constitute a typical design process of Organic Rankine Cycle systems and finds that design problems encountered during design process can be divided into three categories:decision making,parameter optimization and parameter prediction.In the second section,a detailed literature review on each design proce-dures using artificial intelligence algorithms is presented.At last,the state of art in this field and the prospects for the future work are provided.
文摘A simple but illustrative survey is given on various approaches of computational intelligence with their features, applications and the mathematical tools involved, among which the simulated annealing, neural networks, genetic and evolutionary programming, self-organizing learning and adapting algorithms, hidden Markov models are recommended intensively. The common mathematical features of various computational intelligence algorithms are exploited.Finally, two common principles of concessive strategies implicated in many computational intelligence algorithms are discussed.
文摘Information networks are becoming more and more complex to accommodate a continuously increasing amount of traffic and networked devices,as well as having to cope with a growing diversity of operating environments and applications. Therefore,it is foreseeable that future information networks will frequently face unexpected problems,some of which could lead to the complete collapse of a network. To tackle this problem,recent attempts have been made to design novel network architectures which achieve a high level of scalability,adaptability,and robustness by taking inspiration from self-organizing biological systems. The objective of this paper is to discuss biologically inspired networking technologies.
文摘Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest developments in critical care,highlighting key areas of innovation.Recent advancements in critical care include Precision Medicine:Tailoring treatments based on individual patient characteristics,genomics,and biomarkers to enhance the effectiveness of therapies.The objective is to describe the recent advancements in Critical Care Medicine.Telemedicine:The integration of telehealth technologies for remote patient monitoring and consultation,facilitating timely interventions.Artificial intelligence(AI):AI-driven tools for early disease detection,predictive analytics,and treatment optimization,enhancing clinical decision-making.Organ Support:Advanced life support systems,such as Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy provide better organ support.Infection Control:Innovative infection control measures to combat emerging pathogens and reduce healthcare-associated infections.Ventilation Strategies:Precision ventilation modes and lung-protective strategies to minimize ventilatorinduced lung injury.Sepsis Management:Early recognition and aggressive management of sepsis with tailored interventions.Patient-Centered Care:A shift towards patient-centered care focusing on psychological and emotional wellbeing in addition to medical needs.We conducted a thorough literature search on PubMed,EMBASE,and Scopus using our tailored strategy,incorporating keywords such as critical care,telemedicine,and sepsis management.A total of 125 articles meeting our criteria were included for qualitative synthesis.To ensure reliability,we focused only on articles published in the English language within the last two decades,excluding animal studies,in vitro/molecular studies,and non-original data like editorials,letters,protocols,and conference abstracts.These advancements reflect a dynamic landscape in critical care medicine,where technology,research,and patient-centered approaches converge to improve the quality of care and save lives in ICUs.The future of critical care promises even more innovative solutions to meet the evolving challenges of modern medicine.