In this issue of Journal of Biomedical Research,3review articles are published that cover a broad range of topics addressing current understanding on regulation of nutrient metabolism through protein phosphatases,home...In this issue of Journal of Biomedical Research,3review articles are published that cover a broad range of topics addressing current understanding on regulation of nutrient metabolism through protein phosphatases,homeostatic regulation of cellular lipid droplets by small GTPases,and mechanisms by which hepatic assembly and secretion of triglyceride-rich lipoproteins are regulated.展开更多
This paper aims to explore RLC equivalent circuit synthesis method forreduced-order models of interconnect circuits obtained by Krylov subspace basedmodel order reduction (MOR) methods. To guarantee pure RLC equivalen...This paper aims to explore RLC equivalent circuit synthesis method forreduced-order models of interconnect circuits obtained by Krylov subspace basedmodel order reduction (MOR) methods. To guarantee pure RLC equivalent circuitscan be synthesized, both the structures of input and output incidence matrices and theblock structure of the circuit matrices should be preserved in the reduced-order models.Block structure preserving MOR methods have been well established. In this paper,we propose an embeddable Input-Output structure Preserving Order Reduction(IOPOR) technique to further preserve the structures of input and output incidencematrices. By combining block structure preserving MOR methods and IOPOR technique,we develop an RLC equivalent circuit synthesis method RLCSYN (RLC SYNthesis).Inline diagonalization and regularization techniques are specifically proposedto enhance the robustness of inductance synthesis. The pure RLC model, high modelingaccuracy, passivity guaranteed property and SPICE simulation robustness makeRLCSYN more applicable in interconnect analysis, either for digital IC design ormixedsignal IC simulation.展开更多
文摘In this issue of Journal of Biomedical Research,3review articles are published that cover a broad range of topics addressing current understanding on regulation of nutrient metabolism through protein phosphatases,homeostatic regulation of cellular lipid droplets by small GTPases,and mechanisms by which hepatic assembly and secretion of triglyceride-rich lipoproteins are regulated.
基金NSFC research project 90307017 and 60676018partly by the National Basic Research Program of China under the grant 2005CB321701+2 种基金partly by Cross-Century Outstanding Scholar’s fund of Ministry of Education of China,partly by the doctoral program foundation of Ministry of Education of China 20050246082partly by Shanghai Dawn Project 200601partly by the National Science Foundation(NSF)under Grant CCR-0306298.
文摘This paper aims to explore RLC equivalent circuit synthesis method forreduced-order models of interconnect circuits obtained by Krylov subspace basedmodel order reduction (MOR) methods. To guarantee pure RLC equivalent circuitscan be synthesized, both the structures of input and output incidence matrices and theblock structure of the circuit matrices should be preserved in the reduced-order models.Block structure preserving MOR methods have been well established. In this paper,we propose an embeddable Input-Output structure Preserving Order Reduction(IOPOR) technique to further preserve the structures of input and output incidencematrices. By combining block structure preserving MOR methods and IOPOR technique,we develop an RLC equivalent circuit synthesis method RLCSYN (RLC SYNthesis).Inline diagonalization and regularization techniques are specifically proposedto enhance the robustness of inductance synthesis. The pure RLC model, high modelingaccuracy, passivity guaranteed property and SPICE simulation robustness makeRLCSYN more applicable in interconnect analysis, either for digital IC design ormixedsignal IC simulation.