BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberc...BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberculomas only in the cistern are extremely rare with only a few reported cases in the literature.We describe a unique case of isolated tuberculoma in the suprasellar cistern,with only right ocular motility disorder and upper eyelid ptosis.CASE SUMMARY A 5-year-old boy without any medical history presented with right ocular motility disorder and upper eyelid ptosis one month ago.He had no history of fever,headache,vomiting,convulsions,or limb weakness.Neurological examination showed right third cranial nerve palsy with restrictions of eye movements and ptosis,pupil dilation and negative light reflex.Imaging suggested a spaceoccupying lesion in the suprasellar cistern with calcification and ring-enhancement.Moreover,no Mycobacterium tuberculosis was found in cerebrospinal fluid by polymerase chain reaction(PCR).The lesion was initially diagnosed as a tumor,while postoperative pathology combined with PCR indicated tuberculoma.The patient continued postoperative anti-tuberculosis treatment.At present,the patient's condition is stable and the symptoms are partially relieved compared with those before surgery.CONCLUSION This case confirmed that isolated intracranial tuberculoma can occur in the suprasellar cistern.Therefore,for space-occupying lesions in the suprasellar cistern,tuberculoma should be included in the differential diagnosis even if there is no history or indication of tuberculosis infection.展开更多
Tuberculosis involving spinal cord in the form of intramedullary tuberculoma is uncommon,and the concurrent occurrence of cranial and intramedullary tuberculomas is extremely rare.We report a case of disseminated tube...Tuberculosis involving spinal cord in the form of intramedullary tuberculoma is uncommon,and the concurrent occurrence of cranial and intramedullary tuberculomas is extremely rare.We report a case of disseminated tuberculoma involving brain and spinal cord with miliary tuberculosis in a 32‑year‑old male presenting with fever,cerebellar signs and motor weakness of both upper and lower extremities.Based on magnetic resonance imaging and polymerase chain reaction,we diagnosed as tuberculoma.He completely recovered with conventional antituberculous treatment and steroids.The follow‑up of the patient showed disappearance of signs and symptoms.展开更多
文摘BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberculomas only in the cistern are extremely rare with only a few reported cases in the literature.We describe a unique case of isolated tuberculoma in the suprasellar cistern,with only right ocular motility disorder and upper eyelid ptosis.CASE SUMMARY A 5-year-old boy without any medical history presented with right ocular motility disorder and upper eyelid ptosis one month ago.He had no history of fever,headache,vomiting,convulsions,or limb weakness.Neurological examination showed right third cranial nerve palsy with restrictions of eye movements and ptosis,pupil dilation and negative light reflex.Imaging suggested a spaceoccupying lesion in the suprasellar cistern with calcification and ring-enhancement.Moreover,no Mycobacterium tuberculosis was found in cerebrospinal fluid by polymerase chain reaction(PCR).The lesion was initially diagnosed as a tumor,while postoperative pathology combined with PCR indicated tuberculoma.The patient continued postoperative anti-tuberculosis treatment.At present,the patient's condition is stable and the symptoms are partially relieved compared with those before surgery.CONCLUSION This case confirmed that isolated intracranial tuberculoma can occur in the suprasellar cistern.Therefore,for space-occupying lesions in the suprasellar cistern,tuberculoma should be included in the differential diagnosis even if there is no history or indication of tuberculosis infection.
文摘Tuberculosis involving spinal cord in the form of intramedullary tuberculoma is uncommon,and the concurrent occurrence of cranial and intramedullary tuberculomas is extremely rare.We report a case of disseminated tuberculoma involving brain and spinal cord with miliary tuberculosis in a 32‑year‑old male presenting with fever,cerebellar signs and motor weakness of both upper and lower extremities.Based on magnetic resonance imaging and polymerase chain reaction,we diagnosed as tuberculoma.He completely recovered with conventional antituberculous treatment and steroids.The follow‑up of the patient showed disappearance of signs and symptoms.