Effects of intradermal needle therapy plus pinaverium bromide on gastrointestinal hormone levels in irritable bowel syndrome-diarrhea patients

Objective:To observe the clinical efficacy difference in treating irritable bowel syndrome-diarrhea(IBS-D)of liver-qi stagnation and spleen-deficiency pattern with different treatment protocols,and the effects on serum levels of 5-hydroxytryptamine(5-HT),substance P(SP)and vasoactive intestinal peptide(VIP),for unveiling the mechanism of intradermal needle therapy plus pinaverium bromide in treating IBS-D.Methods:A total of 123 IBS-D patients were divided into an observation group,a Western medication group and an integrated Western and Chinese medication group using the random number table method,with 41 cases in each group.The Western medication group was given oral pinaverium bromide,50 mg each time and 3 times a day.The integrated Western and Chinese medication group was given additional Chinese herbal medicine Tong Xie Yao Fang,one dose each day.The observation group was given additional intradermal needle therapy on the basis of the Western medication group.The whole intervention lasted for 6 weeks.Before and after treatment,the scores of gastrointestinal symptoms,traditional Chinese medicine(TCM)symptoms,irritable bowel syndrome(IBS)symptom severity scale(IBS-SSS)and IBS quality of life(IBS-QOL)questionnaire,as well as the serum levels of 5-HT,SP and VIP were observed.The clinical efficacy was estimated.Results:The total effective rate was 92.7%in the observation group,68.3%in the Western medication group and 78.1%in the integrated Western and Chinese medication group.The total effective rate was higher in the observation group than in the other two groups,and higher in the integrated Western and Chinese medication group than in the Western medication group,showing statistical significance(all P<0.05).After treatment,the scores of gastrointestinal symptoms,TCM symptoms and IBS-SSS showed significant decreases in the three groups,presenting statistical significance compared with the baseline(all P<0.05);the scores of gastrointestinal symptoms,TCM symptoms and IBS-SSS were notably lower in the observation group than in the other two groups(all P<0.05),and lower in the integrated Western and Chinese medication group than in the Western medication group(all P<0.05).After treatment,the eight component scores of IBS-QOL showed significant increases in the three groups compared with the baseline(all P<0.05);the eight component scores in IBS-QOL were significantly higher in the observation group than in the other two groups(all P<0.05),and higher in the integrated Western and Chinese medication group than in the Western medication group(all P<0.05).After treatment,the serum levels of 5-HT,SP and VIP decreased markedly in the three groups compared with the baseline(all P<0.05);the serum levels of 5-HT,SP and VIP were significantly lower in the observation group than in the other two groups(all P<0.05),and lower in the integrated Western and Chinese medication group than in the Western medication group(P<0.05).Conclusion:Treatment with intradermal needle therapy plus pinaverium bromide results in significant improvements in the gastrointestinal symptoms and quality of life in patients with IBS-D of liver-qi stagnation and spleen deficiency pattern,and effectively regulates the gastrointestinal hormone production.

Clinical study on intradermal needle therapy in treating urinary retention after cervical cancer surgery

Objective:To observe the clinical efficacy of intradermal needle therapy for urinary retention after cervical cancer surgery.Methods:A total of 100 patients with urinary retention after cervical cancer surgery were randomized into a control group and an observation group,with 50 cases in each group.The control group was treated with basic nursing only,and the observation group was treated with additional intradermal needle therapy.Both groups were treated for 2 courses of treatment.The main symptom scores and residual urine volume of the two groups were observed before and after treatment,and the inpatient time,catheter indwelling time and the clinical efficacy were compared between the two groups.Results:The total effective rate was 96.0%in the observation group and 88.0% in the control group,and the difference between the two groups was statistically significant(P<0.05).After treatment,the main symptom scores and residual urine volume in both groups decreased significantly(all P<0.0S),and the scores and residual urine volume in the observation group were significantly lower than those in the control group(all P<0.05).The inpatient time and catheter indwelling time in the observation group were significantly shorter than those in the control group(both P<0.05).Conclusion:Intradermal needle therapy has an obvious effect in improving symptoms of urinary retention after cervical cancer surgery,and the effect is significantly more persistent than that of simple basic nursing.

Clinical observation of auricular needle-embedding therapy for primary insomnia

Objective:To observe the clinical efficacy of auricular needle-embedding therapy for treating primary insomnia.Methods:A total of 63 patients were randomly divided into a conventional acupuncture group and an auricular needleembedding group.The conventional acupuncture group received acupuncture at meridian points,while the auricular needle-embedding group received acupuncture at auricular points.Treatments were given once a day for 6 consecutive days,followed by a 1-day break,as a course of treatment.Both groups were treated for 2 courses.Before treatment,and after 1 course and 2 courses of treatment,the Pittsburgh sleep quality index(PSQI)score was assessed,and the efficacy was evaluated.Results:The cured and markedly effective rate and total effective rate of the auricular needle-embedding group were higher than those of the conventional acupuncture group,but there was no significant difference between the two groups(P>0.05).After 1 course of treatment,the PSQI global score and the scores of subjective sleep quality,sleep latency,sleep duration,habitual sleep efficiency,and daytime dysfunction of both groups decreased compared with those before treatment(P<0.01);there was no statistical significance in comparing the PSQI global score and individual component scores between the two groups(P>0.05).After 2 courses of treatment,the PSQI global score and the scores of sleep latency and habitual sleep efficiency of the auricular needle-embedding group decreased compared with those after 1 course of treatment(P<0.01 or P<0.05),while only the score of sleep latency of the conventional acupuncture group decreased compared with that after 1 course of treatment(P<0.05);the PSQI global score and the scores of subjective sleep quality and sleep latency of the auricular needle-embedding group were lower than those of the conventional acupuncture group(P<0.05).Conclusion:Both therapies can improve insomnia.Compared to conventional acupuncture,auricular needleembedding therapy demonstrates a therapeutic advantage in improving sleep latency and sleep quality,making it worthy of clinical promotion.

Clinical study of thumb-tack needle therapy for cervical radiculopathy based onmeridian differentiation

Objective:To observe the clinical efficacy and eligibility of thumb-tack needle therapy based on meridian differentiation in treating cervical radiculopathy.Methods:A total of 70 patients with cervical radiculopathy were randomized into an observation group and a control group,with 35 cases in each group.Patients in the control group received thumb-tack needle based on conventional point selection,while those in the observation group received thumb-tack needle according to meridian differentiation.The visual analog scale(VAS)and clinical symptom scores in the two groups were compared before and after treatment,and the clinical efficacy of the two treatments was observed.Results:After treatment,the VAS score in both groups dropped significantly(both P<0.01),and the VAS score in the observation group was lower than that in the control group(P<0.01).The clinical symptoms score in both groups dropped significantly(all P<0.01),and the clinical symptoms score in the observation group was lower than that in the control group(P<0.01).The total effective rate in the observation group was higher than that in the control group(P<0.05).Conclusion:Thumb-tack needle therapy based on meridian differentiation can reduce pain score,improve clinical symptoms in patients with cervical radiculopathy,and produce more significant efficacy compared with conventional thumb-tack needle therapy.

Therapeutic observation of needle embedding for constipation after thoracolumbar vertebral fracture

Objective： To observe the clinical efficacy of point needle embedding in treating constipation after thoracolumbar vertebral fracture. Methods： By random number table based on the admission sequence, 85 patients with constipation after thoracolumbar vertebral fracture were randomized into an observation group of 43 cases and a control group of 42 cases. The observation group was intervened by point needle embedding with intradermal needles, while the control group was by point application with Chinese medication. The clinical efficacies were compared between the two groups after intervention. Results： After treatment, the initial defecation time and bowel movement condition were compared. Despite the residual feeling in the initial defecation, the initial defecation time and bowel movements of the observation group were significantly superior to those of the control group （P〈0.05, P〈0.01）; the total effective rate was 90.7% in the observation group versus 73.8% in the control group, and the difference was statistically significant （P〈0.05）. Conclusion： Point needle embedding can produce a better therapeutic efficacy than Chinese medicinal application in treating constipation after thoracolumbar vertebral fracture; besides, it＇s easy-to-operate.

Observation on efficacy of thumbtack needle combined with pediatric Tuina for constipation in children caused by liver depression and Qi stagnation

Objective To observe the clinical effect of thumbtack needles combined with pediatric Tuina(Chinese therapeutic massage)for constipation in children caused by liver depression and Qi stagnation.Methods A total of 60 children with constipation caused by liver depression and Qi stagnation were randomly divided into a combined group and a Tuina group,with 30 cases in each group.The cases in the Tuina group were treated with pediatric Tuina,while those in the combined group were treated with additional thumbtack needle therapy.We observed the clinical efficacy and the change in the number of spontaneous bowel movements per week before and after treatment.Results After treatment,the cure rate and the total effective rate in the combined group were higher than in the Tuina group,showing statistical significance(P<0.05).Compared with the same group before treatment,the number of spontaneous bowel movements per week in both groups increased after treatment(P<0.05).With the progression of treatment,the number of spontaneous bowel movements per week increased in both groups,and the number in the combined group was more than that in the Tuina group,showing statistical significance(P<0.01).Conclusion Thumbtack needles combined with pediatric Tuina is more effective than pediatric Tuina alone in the treatment of constipation in children caused by liver depression and Qi stagnation.