We devoloped an efficient and simple method to synthesize fluorene derivatives via intramolecular Friedel-Crafts alkylation of chalcones.The transform is catalyzed by TfOH in CH_(3)NO_(2)at 80℃and the yield is up to ...We devoloped an efficient and simple method to synthesize fluorene derivatives via intramolecular Friedel-Crafts alkylation of chalcones.The transform is catalyzed by TfOH in CH_(3)NO_(2)at 80℃and the yield is up to 99%.展开更多
Supramolecular chemistry has received considerable attention in host-guest recognition.The structureresponse relationship of host-guest recognition system is a meaningful issue.Herein,a series of tripodal nitrogen mus...Supramolecular chemistry has received considerable attention in host-guest recognition.The structureresponse relationship of host-guest recognition system is a meaningful issue.Herein,a series of tripodal nitrogen mustard derivatives(TMs)have been developed in this paper.By rationally design the intramolecular alkyl chain lengths of host,the host-guest binding model have been successfully tuned,which underwent a transformation fromπ-πto multiple hydrogen bonds.This process enhances the host-guest binding force and recognition efficiency.展开更多
Zigzag hydrocarbon belts have been fascinating chemists and materials scientists for decades because of their aesthetically appealing molecular structures,outstanding physical properties and intriguing chemical reacti...Zigzag hydrocarbon belts have been fascinating chemists and materials scientists for decades because of their aesthetically appealing molecular structures,outstanding physical properties and intriguing chemical reactivities predicted by theoretical calculations,and potential applications as unique macrocyclic hosts in supramolecular chemistry.They may also serve as templates or seeds to grow structurally well-defined uniform zigzag carbon nanotubes.While there have been continuous computational studies on the structures and properties of belt[n]arenes or[n]cyclacenes since they were proposed as hypothetical molecules in 1954,the synthesis of(partially)conjugated zigzag hydrocarbon belts remains a great challenge,with no progress being reported in the past 20 years.Very recently,we have been witnessing the renaissance of synthetic interest in zigzag hydrocarbon belts,and the formation of the first fully conjugated one is on the horizon.This minireview focuses on the understanding of belt[n]arenes based on theoretical calculations and the synthesis and structure of zigzag hydrocarbon belts.Perspectives on the strategies to isolate and characterize the fully conjugated belt[n]arenes and on the applications of zigzag hydrocarbon belts are also discussed.展开更多
文摘We devoloped an efficient and simple method to synthesize fluorene derivatives via intramolecular Friedel-Crafts alkylation of chalcones.The transform is catalyzed by TfOH in CH_(3)NO_(2)at 80℃and the yield is up to 99%.
基金the support from the National Natural Science Foundation of China(Nos.22165027,22061039,22001214)Key R&D program of Gansu Province(No.21YF5GA066)Gansu Provincial Department of Education:Excellent Postgraduate“Innovation Star”Project(No.2021CXZX-184)。
文摘Supramolecular chemistry has received considerable attention in host-guest recognition.The structureresponse relationship of host-guest recognition system is a meaningful issue.Herein,a series of tripodal nitrogen mustard derivatives(TMs)have been developed in this paper.By rationally design the intramolecular alkyl chain lengths of host,the host-guest binding model have been successfully tuned,which underwent a transformation fromπ-πto multiple hydrogen bonds.This process enhances the host-guest binding force and recognition efficiency.
基金the National Science Foundation of China(grant nos.21732004,21821001,and 91427301)Tsinghua University Initiative Scientific Research Program for financial support.
文摘Zigzag hydrocarbon belts have been fascinating chemists and materials scientists for decades because of their aesthetically appealing molecular structures,outstanding physical properties and intriguing chemical reactivities predicted by theoretical calculations,and potential applications as unique macrocyclic hosts in supramolecular chemistry.They may also serve as templates or seeds to grow structurally well-defined uniform zigzag carbon nanotubes.While there have been continuous computational studies on the structures and properties of belt[n]arenes or[n]cyclacenes since they were proposed as hypothetical molecules in 1954,the synthesis of(partially)conjugated zigzag hydrocarbon belts remains a great challenge,with no progress being reported in the past 20 years.Very recently,we have been witnessing the renaissance of synthetic interest in zigzag hydrocarbon belts,and the formation of the first fully conjugated one is on the horizon.This minireview focuses on the understanding of belt[n]arenes based on theoretical calculations and the synthesis and structure of zigzag hydrocarbon belts.Perspectives on the strategies to isolate and characterize the fully conjugated belt[n]arenes and on the applications of zigzag hydrocarbon belts are also discussed.
