Purpose:The removal of small foreign bodies embedded within the deep soft tissues of the maxillofacial region is a complex and challenging task for maxillofacial surgeons.The purpose of this study was to explore the e...Purpose:The removal of small foreign bodies embedded within the deep soft tissues of the maxillofacial region is a complex and challenging task for maxillofacial surgeons.The purpose of this study was to explore the efficacy of the combination of intraoperative CT and surgical navigation for the removal of small foreign objects in the maxillofacial region.Methods:A serial case study was conducted involving all consecutive patients who underwent surgical removal of small foreign bodies in the maxillofacial region.The combination of intraoperative CT and a surgical navigation system was used at a single medical institution from January 2018 to December 2022.Comprehensive data,including patient demographics,characteristics of the foreign bodies,previous surgical interventions,duration of the surgical procedure,and removal success rate were collected for this study.Relevant data were recorded into Microsoft Excel sheet and analyzed using SPSS version 22.0.Results:Nine patients(6 males and 3 females)were included in this study,with an average age of 37 years.Each patient had previously undergone an unsuccessful removal attempt utilizing conventional surgical methods based on preoperative CT imaging or C-arm guidance at a local healthcare facility.Four patients also experienced unsuccessful attempts with preoperative CT image-based navigation systems.However,by employing the combined approach of intraoperative CT and surgical navigation,the foreign bodies were successfully removed in all 9 patients.The mean duration of the surgical procedure was 59 min,and the average size of the foreign bodies was approximately 26 mm^(3).Postoperative follow-up exceeding 6 months revealed no complications.Conclusion:The combined use of a surgical navigation system and intraoperative CT represents a potent and effective strategy for the precise localization and subsequent removal of small foreign bodies from the soft tissue structures of the maxillofacial region.This integrative approach appears to increase the success rate of surgical interventions in such cases.展开更多
Cholangiocellular cancer(CCC)is an oncological disease of the bile ducts characterized by a high mortality rate.To date,the use of standard methods for the diagnosis and treatment of CCC has not been able to reduce mo...Cholangiocellular cancer(CCC)is an oncological disease of the bile ducts characterized by a high mortality rate.To date,the use of standard methods for the diagnosis and treatment of CCC has not been able to reduce mortality from this disease.This work presents the results of fluorescence diagnostics(FD),which consists in using a modified optical fiber and photodynamic therapy(PDT)using a therapeutic laser instead of a low-intensity laser.This technique was tested on 43 patients in a clinical setting.The results obtained indicate a direct correlation between spectroscopic and video FD methods.Furthermore,a direct correlation was found between the photobleaching of a chlorin e6-based photosensitizer,with the commercial names of PhotoIon Radachlorin and Photoran and stricture regression.Our findings demonstrate the possibility of using a therapeutic laser with a wavelength of 660 nm for both diagnosis and treatment of bile ducts cancer,which results in a significant reduction of the operation time without decreasing its effectiveness.展开更多
基金funded by the Technological Innovation Plan and Innovation Team Project of PLA(2023YXKY005).
文摘Purpose:The removal of small foreign bodies embedded within the deep soft tissues of the maxillofacial region is a complex and challenging task for maxillofacial surgeons.The purpose of this study was to explore the efficacy of the combination of intraoperative CT and surgical navigation for the removal of small foreign objects in the maxillofacial region.Methods:A serial case study was conducted involving all consecutive patients who underwent surgical removal of small foreign bodies in the maxillofacial region.The combination of intraoperative CT and a surgical navigation system was used at a single medical institution from January 2018 to December 2022.Comprehensive data,including patient demographics,characteristics of the foreign bodies,previous surgical interventions,duration of the surgical procedure,and removal success rate were collected for this study.Relevant data were recorded into Microsoft Excel sheet and analyzed using SPSS version 22.0.Results:Nine patients(6 males and 3 females)were included in this study,with an average age of 37 years.Each patient had previously undergone an unsuccessful removal attempt utilizing conventional surgical methods based on preoperative CT imaging or C-arm guidance at a local healthcare facility.Four patients also experienced unsuccessful attempts with preoperative CT image-based navigation systems.However,by employing the combined approach of intraoperative CT and surgical navigation,the foreign bodies were successfully removed in all 9 patients.The mean duration of the surgical procedure was 59 min,and the average size of the foreign bodies was approximately 26 mm^(3).Postoperative follow-up exceeding 6 months revealed no complications.Conclusion:The combined use of a surgical navigation system and intraoperative CT represents a potent and effective strategy for the precise localization and subsequent removal of small foreign bodies from the soft tissue structures of the maxillofacial region.This integrative approach appears to increase the success rate of surgical interventions in such cases.
基金This work was funded by RFBR according to the research project(Nos.17-00-00162 and 17-00-00159).
文摘Cholangiocellular cancer(CCC)is an oncological disease of the bile ducts characterized by a high mortality rate.To date,the use of standard methods for the diagnosis and treatment of CCC has not been able to reduce mortality from this disease.This work presents the results of fluorescence diagnostics(FD),which consists in using a modified optical fiber and photodynamic therapy(PDT)using a therapeutic laser instead of a low-intensity laser.This technique was tested on 43 patients in a clinical setting.The results obtained indicate a direct correlation between spectroscopic and video FD methods.Furthermore,a direct correlation was found between the photobleaching of a chlorin e6-based photosensitizer,with the commercial names of PhotoIon Radachlorin and Photoran and stricture regression.Our findings demonstrate the possibility of using a therapeutic laser with a wavelength of 660 nm for both diagnosis and treatment of bile ducts cancer,which results in a significant reduction of the operation time without decreasing its effectiveness.